Download or read book Hepatotoxicity written by Hyman J. Zimmerman and published by Lippincott Williams & Wilkins. This book was released on 1999 with total page 850 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by the foremost authority in the field, this volume is a comprehensive review of the multifaceted phenomenon of hepatotoxicity. Dr. Zimmerman examines the interface between chemicals and the liver; the latest research in experimental hepatotoxicology; the hepatotoxic risks of household, industrial, and environmental chemicals; and the adverse effects of drugs on the liver. This thoroughly revised, updated Second Edition features a greatly expanded section on the wide variety of drugs that can cause liver injury. For quick reference, an appendix lists these medications and their associated hepatic injuries. Also included are in-depth discussions of drug metabolism and factors affecting susceptibility to liver injury.

Download or read book Coronary Primary Prevention Trial written by and published by . This book was released on 1984 with total page 2 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Statin Associated Muscle Symptoms written by Paul D. Thompson and published by Springer Nature. This book was released on 2020-01-25 with total page 191 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an overview of statin-associated muscle symptoms (SAMS) from clinical presentation to treatment and possible metabolic causes. It examines the risk factors, presentations, diagnosis and differential diagnosis, clinical management, and financial costs of SAMS. The book also highlights patients’ perspectives on SAMS such as the psychosocial, emotional, and societal factors influencing their perceptions and experiences. Finally, the book presents the results of observational and clinical trials on the prevalence of SAMS, clinical trials for treatments, and potential future research approaches for improving the understanding and treatment of SAMS. A key addition to the Contemporary Cardiology series, Statin-Associated Muscle Symptoms is an essential resource for physicians, medical students, residents, fellows, and allied health professionals in cardiology, endocrinology, pharmacotherapy, primary care, and health promotion and disease prevention.

Download or read book Antilipidemic Drugs written by Donald T. Witiak and published by Elsevier Publishing Company. This book was released on 1991 with total page 624 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clearly, a major disorder of these times is Coronary Heart Disease (CHD) with atherosclerosis being the underlying cause. The biochemistry of this multifaceted disease of lipid and lipoprotein metabolism, our understanding of atherogenesis, and the medicinal chemical basis of antilipidemic and antiatherogenic organic chemicals have recently undergone major advances. These advances, the major epidemiological studies and drug trials involved, are well reflected in this book, along with information demonstrating treatment efficacy of diet and pharmaceuticals in both animal and clinical trials and a mechanism-based understanding of these treatment modalities. The physiology and pathophysiology of lipid and lipoprotein metabolism and the relationship of the underlying metabolic processes to the development of the atherosclerotic plaque are also covered, as are many more topics in this extensive treatize. The 17th volume in this well-known series, it provides up-to-date coverage of the medicinal, chemical and biochemical aspects of antilipidemic drugs.

Download or read book Drug Induced Liver Injury written by and published by Academic Press. This book was released on 2019-07-13 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug-Induced Liver Injury, Volume 85, the newest volume in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this new release include Cell death mechanisms in DILI, Mitochondria in DILI, Primary hepatocytes and their cultures for the testing of drug-induced liver injury, MetaHeps an alternate approach to identify IDILI, Autophagy and DILI, Biomarkers and DILI, Regeneration and DILI, Drug-induced liver injury in obesity and nonalcoholic fatty liver disease, Mechanisms of Idiosyncratic Drug-Induced Liver Injury, the Evaluation and Treatment of Acetaminophen Toxicity, and much more. - Includes the authority and expertise of leading contributors in pharmacology - Presents the latest release in the Advances in Pharmacology series

Download or read book Pharmacology for Canadian Health Care Practice written by Linda Lane Lilley and published by Elsevier Health Sciences. This book was released on 2017-01-20 with total page 1191 pages. Available in PDF, EPUB and Kindle. Book excerpt: Designed with the student in mind, and easy to read and use, the new 2nd edition of Lilley will cover all the key pharmacology content needed by Canadian nursing students. Known for its appealing layout, plenty of photos, and numerous helpful boxed features, Lilley helps students manage the extremely detailed subject of pharmacology. This edition focuses on the role of nurses and their practices in culturally diverse Canada, and includes new content on natural health products and ethnocultural considerations. Evidence-Informed Practice Boxes: Provide a bridge between research evidence and its relevance to nursing practice Laboratory Values Related to Drug Therapy: Provide normal ranges and values for specific lab tests, and rationales for lab assessments in relation to specific drug therapy UNIQUE! In My Family Boxes: Written by nursing students of various ethnocultural backgrounds, relaying their cultural health beliefs and practices and drug use Preventing Medication Errors Boxes: Reinforce concepts introduced in the medication errors chapter and relate them to specific common errors that occur in clinical practice. Special Populations: Women: In addition to other special populations, some boxes specifically focus on women’s health UNIQUE! Tear out cards from Mosby’s Pharmacology Memory NoteCards Increased pathophysiology coverage: Introduces key chapters to provide students with a brief overview before launching into drug information Chapters on Antibiotics and Antineoplastics: Subjects have both been divided into two chapters each, making difficult material easier to digest for students Generic and trade drug names are used throughout – with a new Drug Index at the back of the book Emphasis on nursing roles and practices in Canada More info on natural health products More info on ethnocultural considerations

Download or read book Prescribing in Pregnancy written by Peter C. Rubin and published by John Wiley & Sons. This book was released on 2008-04-30 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: This thoroughly revised edition of Prescribing in Pregnancy is a practical and authoritative guide for all doctors who prescribe for pregnant women. Covering both the prescribing of drugs for common conditions in pregnant women and the effect of different drugs on pregnancy, the fourth edition now also features: strengthened evidence for the prescribing regimens updated prescribing information throughout a new user-friendly design Written by leading specialists, Prescribing in Pregnancy covers the common medical problems encountered in pregnancy, and includes information on travel medicine, breast feeding and the management of drug and alcohol abuse. The fourth edition of this comprehensive and relevant book is an invaluable reference for the busy doctor, on the wards and in general practice.

Download or read book Drugs During Pregnancy and Lactation written by Christof Schaefer and published by Elsevier. This book was released on 2011-10-13 with total page 907 pages. Available in PDF, EPUB and Kindle. Book excerpt: The latest edition is the resource for any practicing OB/GYN, family physician, midwife, or pharmacist who prescribes medicinal products to or evaluates environmental or occupational exposures in women who are or may become pregnant. Based on the highly successful seven German editions of this reference, the up-to-date drug listings have been revised into a handy pocket guide color tabbed for quick access to important information. Easy to reference each drug is listed discussing the side effects, general impact on organ systems, potential toxicity, and risks before offering dosage recommendations. It is the only book of its kind to provide conclusive information on treatments for diseases during pregnancy and lactation and actions to be taken after (inadvertant) exposure to drugs suspected to be developmentaly toxic. Unlike other dosage guides, this edition is an affordable, compact compendium of knowledge on the very latest drugs and their effects on pregnant/lactating women. - Provides conclusive information on the prevention of birth defects through the safe use of drugs before pregnancy, as well as during pregnancy and lactation - Essential new information on herbs, vitamins, and nutrition supplements used during pregnancy - Structured according to indication group, rather than alphabetically, providing a more user-friendly guide that makes it easier to compare drugs - Includes a conveniently removable 'quick reference' card of most frequently used drugs and their safety

Download or read book Understanding Drug Action written by Peter J. Rice and published by Amer Pharmacists Assn. This book was released on 2013-11-11 with total page 335 pages. Available in PDF, EPUB and Kindle. Book excerpt: Understanding Drug Action: An Introduction to Pharmacology provides readers with a survey of the scientific understanding of drug action. This readable introduction to pharmacology is simple enough to be understood without having to take a class to follow the material, but can also be used to complement a course in pharmacology. The approach to pharmacology is at a basic scientific level to build a framework of how drugs work supplemented with information on some representative drugs that are used clinically. Each chapter includes review questions and many chapters include tables of important drugs with brand and generic names.

Download or read book Highlights of the Report of the Expert Panel on Blood Cholesterol Levels in Children and Adolescents written by National Cholesterol Education Program (U.S.). Expert Panel on Blood Cholesterol Levels in Children and Adolescents and published by . This book was released on 1991 with total page 14 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Piperidine Based Drug Discovery written by Ruben Vardanyan and published by Elsevier. This book was released on 2017-06-12 with total page 359 pages. Available in PDF, EPUB and Kindle. Book excerpt: Piperidine-Based Drug Discovery outlines the complexities of Piperidine scaffold use in drug discovery, including derivative chemistry, structural properties, methods of synthesis and practical implementations. Piperidine scaffolds are the cornerstones of over 70 commercialized drugs (including multiple blockbusters). Designed as a guide for both experts and students working in this and related areas, it is hoped that this volume will encourage and inspire the continued design and development of novel pharmaceuticals based on Piperidine and its derivatives. Heterocyclic compounds are of central importance to medicinal chemistry, as demonstrated by the high percentage of marketable drugs that feature heterocyclic fragments in their structures. As starting points for drug discovery they offer a broad range of attractive properties, and a detailed understanding of the particular characteristics of each is of great benefit to researchers. The most commonly used heterocycle among US FDA approved pharmaceuticals, Piperidine is an extremely important building block in the synthesis of medicinal agents. This heterocycle and its derivatives exhibit a number of important functionalities and have been employed variously as CNS modulators, antiaggregants, anticoagulants, antihistamines, anti-cancer drugs and analgesics. - Explores this extremely important heterocycle to a high level of detail - Describes synthesis methods for 70 current drugs based on Piperidine scaffolds - Gives drug designers all the key knowledge required to develop new drugs utilizing Piperidine - Provides pharmacologists a solid overview of the chemical background of existing Piperidine-based drugs

Download or read book Drug Transporters written by Martin F. Fromm and published by Springer Science & Business Media. This book was released on 2010-11-19 with total page 457 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is increasingly recognized that various transporter proteins are expressed throughout the body and determine absorption, tissue distribution, biliary and renal elimination of endogenous compounds and drugs and drug effects. This book will give an overview on the transporter families which are most important for drug therapy. Most chapters will focus on one transporter family highlighting tissue expression, substrates, inhibitors, knock-out mouse models and clinical studies.

Download or read book Management of Dyslipidemia written by Wilbert S. Aronow and published by BoD – Books on Demand. This book was released on 2021-07-21 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dyslipidemia is a major risk factor for cardiovascular events, cardiovascular mortality, and all-cause mortality. The earlier in life dyslipidemia is treated, the better the prognosis. The current book is an excellent one on dyslipidemia written by experts on this topic. This book includes 12 chapters including 5 on lipids, 4 on hypercholesterolemia in children, and 3 on the treatment of dyslipidemia. This book should be read by all health care professionals taking care of patients, including pediatricians since atherosclerotic cardiovascular disease begins in childhood.

Download or read book The ESC Handbook on Cardiovascular Pharmacotherapy written by Juan Carlos Kaski and published by . This book was released on 2019 with total page 961 pages. Available in PDF, EPUB and Kindle. Book excerpt: The ESC Handbook on Cardiovascular Pharmacotherapy, based on the most recent guidelines in cardiovascular pharmacology, and containing a comprehensive A-Z formulary of common and less commonly used cardiac drugs and drug groups, provides practical and accessible guidance on all areas of drug prescribing.

Download or read book Anticoagulant Drugs written by Mojca Božič-Mijovski and published by BoD – Books on Demand. This book was released on 2018-08-29 with total page 122 pages. Available in PDF, EPUB and Kindle. Book excerpt: Anticoagulant drugs are among the most frequently prescribed drugs in everyday clinical practice. In the past decades, several new direct oral anticoagulants were developed that changed the anticoagulant therapy landscape considerably. This book provides an extensive overview of all the known anticoagulants that can be useful for studying different aspects of the haemostatic system or as a starting point for new drug development. It is also a valuable tool for clinicians providing a description of the mode of action and management of therapy for anticoagulant drugs used in everyday clinical practice in different clinical settings, including direct oral anticoagulants dabigatran, rivaroxaban, apixaban and edoxaban.

Download or read book Pharmacology Review A Comprehensive Reference Guide for Medical Nursing and Paramedic Students written by S. Meloni and published by . This book was released on 2021-02-07 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pharmacology doesn't have to be hard! Here's why: At Medical Creations, we are firm believers of the notion that the best way to learn a new topic is first to understand the fundamentals. Once you know the fundamentals, you will be able to understand the bigger picture. If you don't understand the bigger picture, forcing yourself to memorize any details becomes that much harder. Our Pharmacology book is meant to give you a good understanding of the topic before you can dive into the details with other, more extensive pharmacology books. The goal is to have you understand rather than memorize. It's a great alternative to the thicker and more expensive pharmacology books if you are studying for an exam and you just want a quick recap, or if you are just starting out and you want an overview. The purpose of this pharmacology book is to serve as a reference manual and a comprehensive study guide for medical, nursing, and paramedic students. For easy understanding of this complex subject, the book has been divided into multiple units based on each body system. The addition of multiple-choice questions will make it easier for you to remember the information from previous chapters. The key therapeutic drug classes for each major system have been outlined in separate chapters. Bullet points and tables make the content easy to understand. Pharmacology is a constantly evolving field, and new drugs are being developed every day. The main aim of this book is to familiarize the reader with the different categories of drugs. The most commonly prescribed drugs are described here, but the book is by no means exhaustive and does not cover all the drugs available today. For detailed descriptions of the latest drugs on the market, and less commonly prescribed drugs, the reader is referred to one of the more exhaustive textbooks of pharmacology. This book will help you: * ..Have a clear understanding of pharmacology * ..Learn about different groups of drugs, the pharmacokinetics, and the pharmacodynamics * ..Find pharmacology much more bearable Go to the top-right of the page and click "Add to Cart"

Download or read book Clinical Lipidology written by Christie M. Ballantyne and published by Elsevier Health Sciences. This book was released on 2009-01-01 with total page 605 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical Lipidology, a companion to Braunwald's Heart Disease, is designed to guide you through the ever-changing therapeutic management of patients with high cholesterol levels. From basic science to pathogenesis of atherothrombotic disease, to risk assessment and the latest therapy options, this medical reference book offers unparalleled coverage and expert guidance on lipidology in a straightforward, accessible, and user-friendly style. Get authoritative guidance from some of the foremost experts in the field. Easily access key content with help from treatment algorithms. Access options and evidence-based solutions for every type of patient scenario, as well as the latest clinical guidelines and clinically relevant evidence on risk assessment, special patient populations, and therapy, including recently approved and experimental therapies. Remain at the forefront of the cardiology field with up-to-date chapters on treatment guidelines; diet, exercise, and weight loss; pharmacologic therapies such as statins, omega-3 fatty acids, and combination therapy; evolving targets of therapy such as PCSK9 inhibition, CETP inhibition, and inflammation Prepare for special patient populations such as children and adolescents; women and the elderly; transplant recipients; HIV patients; and those with chronic renal disease, familial hypercholesterolemia, other severe hypercholesterolemias, diabetes, or other metabolic syndromes. Take advantage of a format that follows that of the well-known and internationally recognized Braunwald's Heart Disease. Expert Consult eBook version included with purchase.