Download or read book Animal Models in Dermatology Relevance to Human Dermatopharmacology and Dermatotoxicology written by Howard I. Maibach and published by . This book was released on with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Animal Models in Dermatology written by Howard I. Maibach and published by . This book was released on 1975 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Animal Models of T Cell Mediated Skin Diseases written by T. Zollner and published by Springer Science & Business Media. This book was released on 2007-01-19 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pharmaceutical companies are spending increasing amounts of money on drug discovery and development. Nevertheless, attrition rates in clinical development are still very high, and up to 90% of new compounds fail in clinical phase I - III trials, which is partially due to lack of clinical efficacy. This indicates a strong need for highly predictive in vitro and in vivo models. The "50th International Workshop of the Ernst Schering Research Foundation" focussed on "Animal Models of T Cell-Mediated Skin Diseases". Such animal models should have impact not only on inflammatory dermatoses but also on other inflammatory disorders due to their model character. The current volume summarises recent advances in animal research that are important for anti-inflammatory drug discovery.
Download or read book Animal models in dermatology written by Howard I. Maibach and published by . This book was released on 1975 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Animal Models in Dermatology Relevance to Human Dermatopharmacology and Dermatotoxicology a symposium held in San Francisco CA September 1974 written by Maibach H Ed and published by . This book was released on 1975 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Animal Models of Human Inflammatory Skin Diseases written by Lawrence S. Chan and published by CRC Press. This book was released on 2003-12-29 with total page 584 pages. Available in PDF, EPUB and Kindle. Book excerpt: Progress in understanding skin diseases has been aided enormously by the use of tissues derived from animals, by studying normal processes in animals, and by the development of animal models. The cellular activities in animals and humans are remarkably similar and the actual pathological process of an inflammatory skin disease can only be accurately observed and analyzed in a living animal model, and not in any in vitro model system. These factors have led to the regular use of animal tissues and models to allow the disease processes to be studied at a much greater depth. Animal Models of Human Inflammatory Skin Diseases features the principles and practices of how to go about studying inflammatory skin diseases using live animal models. On the principle side, the book describes the comparative structure and function of the skin, and the comparative immunology system in animal species commonly used as models. From the practical perspective, it presents a general discussion on methods of experimental animal modeling and contains specific expert experience on individual models. The authors include a detailed method of disease induction for each model, present chapters on comparative histology and immunology, and discuss potential targets of disease intervention. Written by biomedical investigators with first-hand experience in their chosen fields, this book is a valuable guide and reference for investigators in the biomedical and pharmaceutical sciences. It provides an instantaneous comparison between the skin structure and immunology of humans and animals, aiding in the interpretation and application of pathologic and immunologic findings.
Download or read book Handbook of Mouse Mutations with Skin and Hair Abnormalities written by John P. Sundberg and published by CRC Press. This book was released on 2020-08-26 with total page 582 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Mouse Mutations with Skin and Hair Abnormalities presents 48 mouse mutations that are all available to the biomedical community. Many of the mouse mutations with dermatological diseases are reviewed and illustrated in detail. This popular reference book gives you a single source to use when determining which mouse mutation will best serve your needs as a biomedical tool for sophisticated research projects. The book also includes an overview of domestic animal genodermatoses to provide alternatives to mouse models that do not exist or to complement those that do. A detailed section written by renowned experts compares the biology of human and mouse skin and skin diseases in the areas of development and the use of animal models, mammalian genetics, keratin biochemistry, epidermal and hair follicle cycles and kinetics, cytokines and growth factors, keratinocyte culture systems, cutaneous carcinogenesis, cutaneous immune system, and skin changes associated with mutations of the endocrine system.
Download or read book Small Animal Dermatology Secrets E Book written by Karen L. Campbell and published by Elsevier Health Sciences. This book was released on 2004-02-09 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: This full-color dermatology text provides essential, practical information for solving dermatological problems commonly encountered in small animals. Organized by disorder type, the popular question-and-answer format and detailed index make it easy to find vital information. In more than 50 chapters, the expert contributors propose key questions and provide authoritative answers about the diagnosis and treatment of dermatologic conditions relevant to small animal veterinary practice.
Download or read book Molecular Dermatology written by Natalia V. Botchkareva and published by Humana. This book was released on 2020-04-21 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume delivers the most important laboratory techniques that underlie dermatological investigation, including in situ, in vitro, ex vivo, and in vivo models of skin, its appendages (hair follicles, sebaceous and sweat glands), and immune cells. Also included are unique techniques that unravel epigenetic mechanisms in skin and hair follicle cells, such as gene organization in the nucleus and gene expression regulation by the non-coding transcriptome, which are important recent developments in investigative dermatology. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Molecular Dermatology: Methods and Protocols serves as an essential resource for researchers working in the areas of fundamental as well as applied dermatological science.
Download or read book Hair Research written by C.E. Orfanos and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 903 pages. Available in PDF, EPUB and Kindle. Book excerpt: Several years ago a friendly looking young man walked into my office at the University Department of Dermatology in Cologne, introduced himself as a diplomate chemist, executive member of a family-owned, rather small German company manufacturing hair care products, and proposed to me straight forward to organize an international meeting on hair research. In view of the large number of new developments in the field something like this should be done after all, he said; he also promised to provide financial support. Such a meeting should be on the highest possible level, I said; and he agreed. I took the challenge and my visitor kept his promise. Three years later the First International Hair Congress was organized at the sophisticated new Congress Center in Hamburg, in which 630 participants from 36 countries were registered. After three and a half days of formal sessions, informal discussions, workshops and poster presentations our unanimous feeling was that this has been a most successful meeting. The young chemist was right. The idea was excellent. The growth and presence of hair and its distribution over the human body as a cosmetic attribute has become during the last two decades a matter of tremendous emotional significance. Hair can be rather easily formed according to one's sence of style, representing his personal image and his social feeling. If it becomes unacceptable or out of fashion, the hair style can be easily changed; the hair regrows as a biological requisite, without any additional cost.
Download or read book Animal Models of T Cell Mediated Skin Diseases 2005 written by and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Animal Models in Eye Research written by and published by Academic Press. This book was released on 2011-04-28 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: The eye is a complex sensory organ, which enables visual perception of the world. Thus the eye has several tissues that do different tasks. One of the most basic aspects of eye function is the sensitivity of cells to light and its transduction though the optic nerve to the brain. Different organisms use different ways to achieve these tasks. In this sense, eye function becomes a very important evolutionary aspect as well. This book presents the different animal models that are commonly used for eye research and their uniqueness in evaluating different aspects of eye development, evolution, physiology and disease. Presents information on the major animal models used in eye research including invertebrates and vertebrates Provides researchers with information needed to choose between model organisms Includes an introductory chapter on the different types of eyes, stressing possible common molecular machinery
Download or read book What Will We Do If We Don t Experiment on Animals written by Jean Swingle Greek and published by Trafford Publishing. This book was released on 2004 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drs. Greek have written 2 books on why using animals as models for humans is not the best way to conduct medical research and drug testing. During their lectures and debates, the most commonly asked question was, "Well. What will we use if we don't use animals?" What Will We Do If We Don't Experiment On Animals? Medical Research for the Twenty-first Century is the answer to that question. Drs. Greek explain briefly why one species cannot predict drug response for another and describe what research and testing methods should be used today instead of animals. They also describe where our biomedical research dollars should be spent if we are to have cures for cancer, AIDS, and Alzheimer's. This book will appeal to science-trained and general audiences, animal lovers and science readers, public policy analysts, students, patients and patient support groups, and government watchdog groups. What Will We Do If We Don't Experiment On Animals? Medical Research for the Twenty-first Century takes medical research out of the nineteenth and into the 21st century.
Download or read book Animal Models in Medicine and Biology written by Eva Tvrdá and published by BoD – Books on Demand. This book was released on 2020-04-08 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thanks to animal models, our knowledge of biology and medicine has increased enormously over the past decades, leading to significant breakthroughs that have had a direct impact on the prevention, management and treatment of a wide array of diseases.This book presents a comprehensive reference that reflects the latest scientific research being done in a variety of medical and biological fields utilizing animal models. Chapters on Drosophila, rat, pig, rabbit, and other animal models reflect frontier research in neurology, psychiatry, cardiology, musculoskeletal disorders, reproduction, chronic diseases, epidemiology, and pain and inflammation management. Animal Models in Medicine and Biology offers scientists, clinicians, researchers and students invaluable insights into a wide range of issues at the forefront of medical and biological progress.
Download or read book Handbook of Atopic Eczema written by Thomas Ruzicka and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 491 pages. Available in PDF, EPUB and Kindle. Book excerpt: State-of-the-art review on atopic eczema, one of the most common skin diseases today. This multi-authored handbook covers all aspects relevant for physicians from various disciplines.
Download or read book Cutaneous Wound Healing written by Vincent Falanga and published by CRC Press. This book was released on 2001-08-23 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gene therapy, bioengineered skin, and other methods in advanced biology are revolutionizing the treatment of wounds. Written by experts in research and clinical practice, Cutaneous Wound Healing examines the current knowledge and emerging treatment methods. This volume explains the normal molecular and cellular functions that occur when a wound heals, as well as dysfunctional events, such as a chronic wound or an ulcer. Such dysfunctions signal an imbalance in the body, explained here along with possible treatments. The book's mini-atlas is an indispensable reference tool. Dermatologists, plastic surgeons, and general practitioners can benefit from this text.
Download or read book Zoobiquity written by Dr. Barbara N. Horowitz and published by Doubleday Canada. This book was released on 2012-06-12 with total page 451 pages. Available in PDF, EPUB and Kindle. Book excerpt: Engaging science writing that bravely approaches a new frontier in medical science and offers a whole new way of looking at the deep kinship between animals and human beings. Zoobiquity: a species-spanning approach to medicine bringing doctors and veterinarians together to improve the health of all species and their habitats. In the tradition of Temple Grandin, Oliver Sacks, and Neil Shubin, this is a remarkable narrative science book arguing that animal and human commonality can be used to diagnose, treat, and ultimately heal human patients. Through case studies of various species--human and animal kind alike--the authors reveal that a cross-species approach to medicine makes us not only better able to treat psychological and medical conditions but helps us understand our deep connection to other species with whom we share much more than just a planet. This revelatory book reaches across many disciplines--evolution, anthropology, sociology, biology, cutting-edge medicine and zoology--providing fascinating insights into the connection between animals and humans and what animals can teach us about the human body and mind.
