Download or read book An Infectious Origin of Alzheimer s Disease An End for This Devastating Disorder written by Judith Miklossy and published by Frontiers Media SA. This book was released on 2020-08-10 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book An Infectious Origin of Alzheimer s Disease An End for This Devastating Disorder written by Judith Miklossy and published by . This book was released on 2020 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Download or read book Alzheimer s Disease and Infectious Causes written by Elaine A. Moore and published by McFarland. This book was released on 2020-04-01 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the recent discovery that amyloid beta protein, the cause of plaques in Alzheimer's disease, is an antimicrobial peptide produced in response to infection, many researchers are focusing on the role infection plays in the development of Alzheimer's disease. Brain studies have also identified a number of different viruses, bacteria, fungi, and protozoa in the postmortem brain specimens of Alzheimer's patients. Infection (particularly chronic, latent and persistent infections) causes an immune response that leads to inflammation and brain cell degeneration, which are characteristic features of Alzheimer's disease. Sources of infection in Alzheimer's disease vary from childhood infections to gut microbes that find their way into the brain as a result of aging, leaky gut syndrome, and increased permeability of the blood brain barrier. Studies and ongoing clinical trials show that treatment of viral and bacterial infections, as well as restoring a healthy balance to the gut microbiome, can reduce disease risk and improve symptoms in patients with Alzheimer's disease. This book serves as an introduction to the human microbiome and the role that infection plays in the development of Alzheimer's disease.
Download or read book The End of Alzheimer s written by Thomas J. Lewis and published by Academic Press. This book was released on 2017-05-12 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: The End of Alzheimer's: The Brain and Beyond, Second Edition is the first comprehensive overview on the molecular basis of Alzheimer's outside of the brain, merging the most recent findings within the field into a single book. It aims to educate the reader on the many overlooked aspects of Alzheimer's disease that occur outside the brain. This book uniquely provides step-by-step, peer-reviewed evidence that the current research model may be misguided and that a new and emerging model is more accurate. It carefully outlines the molecular research in Alzheimer's outside the brain and argues that a more thorough, whole-body diagnosis will provide better answers about its causes and lead to new treatments. It is beneficial to researchers who need to be apprised of the emerging science on the causes of Alzheimer's, and will hopefully redirect many into new avenues of cellular research and discovery. - Comprehensive literature-based summary of the current state of molecular Alzheimer's disease research - Details the shortcomings of the prevailing model and therapeutics in development - Reviews blood-based biomarkers for Alzheimer's and their link to amyloid- and Tau-independent causes outside the brain - Describes the tissues outside the brain impacted by Alzheimer's and the underlying molecular causes - Explains the whole-body risks associated with Alzheimer's, along with concomitant measures to slow or prevent the disease - Provides a protocol to properly research, evaluate, measure, diagnose, and potentially treat Alzheimer's patients
Download or read book Handbook of Infection and Alzheimer s Disease written by J. Miklossy and published by IOS Press. This book was released on 2017-03-10 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alzheimer’s disease is one of the biggest emerging public health problems in the world. Although the last four decades have yielded important insights into the pathogenesis of Alzheimer’s disease, its cause is still unclear, and if it is not discovered the world will face an unprecedented healthcare problem by the middle of this century. In recent years, evidence of the microbial origin of various chronic inflammatory disorders – including several neurodegenerative, neuropsychiatric and other systemic disorders – has been steadily growing. Accumulating new and historic observations are providing evidence of an association between Alzheimer’s disease and certain infectious agents, and may offer new opportunities for ground-breaking healthcare solutions. This handbook assembles and connects findings with regard to the infectious origin of Alzheimer’s disease, and the data presented in its chapters deserves the attention of the neuroscience community, physicians and the health departments of governments worldwide by virtue of its amount and quality. This handbook offers a comprehensive overview of the current knowledge regarding the topic of infection and Alzheimer’s disease, which could pinpoint the cause of this disease. Influential diagnosis, treatment and prevention strategies may also emerge from this crucial research area.
Download or read book End Of Memory written by Jay Ingram and published by HarperCollins. This book was released on 2014-12-30 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: Canada’s bestselling science writer illuminates the mysteries of Alzheimer’s disease, one of the most puzzling and debilitating conditions of the modern era It is a wicked illness that robs its victims of their memories, their ability to think clearly and, ultimately, their lives. For centuries, those afflicted by Alzheimer’s disease have been forced to suffer its devastating effects while family members sit by, watching their loved ones disappear a little more each day, until the person they used to know is gone forever. The disease was first described by pioneering German neurologist Alois Alzheimer in 1906. One hundred years and a great deal of scientific effort later, much more is known about Alzheimer’s, but it still affects millions around the world, and there is no cure in sight. In The End of Memory, award-winning science writer Jay Ingram charts the history of the disease from before it was noted by Alois Alzheimer right through to the twenty-first century, as researchers continue to search for a cure. In the spirit of Siddhartha Mukherjee’s The Emperor of All Maladies, this book is for those who want to find out the truth about an affliction that courses through families and, in some cases, inexplicably affects people early in their lives.
Download or read book The End of Memory written by Jay Ingram and published by Macmillan. This book was released on 2015-09-29 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: An illuminating biography of "the plague of the twenty-first century" and scientists' efforts to understand and, they hope, prevent it, The End of Memory is a book for those who want to find out the true story behind an affliction that courses through families and wreaks havoc on the lives of millions. It is a wicked disease that robs its victims of their memories, their ability to think clearly, and ultimately their lives. For centuries, those afflicted by Alzheimer's disease have suffered its debilitating effects while family members sit by, watching their loved ones disappear a little more each day until the person they used to know is gone forever. The disease was first described by German psychologist and neurologist Alois Alzheimer in 1906. One hundred years and a great deal of scientific effort later, much more is known about Alzheimer's, but it still affects millions around the world, and there is no cure in sight. In The End of Memory, award-winning science author Jay Ingram writes a biography of this disease that attacks the brains of patients. He charts the history of the disease from before it was noted by Alois Alzheimer through to the twenty-first century, explains the fascinating science of plaques and tangles, recounts the efforts to understand and combat the disease, and introduces us to the passionate researchers who are working to find a cure.
Download or read book The End of Alzheimer s written by Thomas J Lewis Ph D and published by Tjlphd, LLC. This book was released on 2014-12-22 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is hope for sufferers of Alzheimer's disease and for those concerned about their future risk for the disease. The solution lies in the diagnosis, not in the treatments designated for the disease today. Alzheimer's is NOT a disease exclusively of the brain. A thorough broad and deep diagnosis of your entire health will often provide answers about the causes of Alzheimer's. With this knowledge in hand, you and your doctor may take measures to prevent, slow, stop, or reverse Alzheimer's and other forms of dementia. In "The End of Alzheimer's - A Differential Diagnosis Toward a Cure." Drs. Lewis and Trempe explore the disease and a proper diagnosis in detail. They describe the pitfalls and shortcoming of current medical research and clinical medicine. Most importantly they provide a simplified guide through a mountain of emerging science and medical information and explain what to obtain for a proper and comprehensive diagnosis, why there is hope for disease sufferers today, and forecast optimism for effective treatments in the future. They also include a 5-phase program to prevent Alzheimer's, diagnosis the disease in asymptomatic people, find route causes of the disease, and offer disease management and treatment advice. Here is what experts are saying about "The End of Alzheimer's?" Dr. Alzheimer, for whom Alzheimer's disease is named, would be totally perplexed and disheartened at the fact that after a century of research and over 100,000 scientific and medical papers written on the subject, patients presently diagnosed with Alzheimer's disease are no better off now than they were in 1907, when he diagnosed the first Alzheimer's case. This fact alone invites the troubling question, are we on the right track to finding a way to help Alzheimer patients? To search for an answer to this consequential question, one needs to read "The End of Alzheimer's?" by Dr. Thomas Lewis and Dr. Clement Trempe who write about this disquieting problem and possible ways to solve it. Drs. Lewis and Trempe have written a mind-opening, well-informed and intelligent account of the history, present and future interventions, and distillation of keen thinking on the subject of Alzheimer's disease. This book will be the focus of many prospective and pivotal discussions on how medical research will eventually govern this mind-shattering disorder. Jack C. de la Torre, MD, PhD, Professor of Psychology, University of Texas, Austin Austin, Texas 79712, Senior Editor, Journal of Alzheimer's Disease The brilliant strategy by Drs. Lewis and Trempe takes advantage of revolutionary new concepts for guiding enhancement of immune function and treatment of chronic infections in prevention and treatment of Alzheimer's disease. The diagnosis of mild cognitive impairment by psychological testing, combined with assessment of ophthalmological abnormalities and determination of health status through thorough testing of biochemical markers related to infection and inflammation, are necessary for improving the prognosis and reducing the risk of dementia. The implications of this strategy for the individual and for the population are enormous. Control of dementia, atherosclerosis, and degenerative diseases of aging by the insights of Drs. Lewis and Trempe has the potential for revolutionizing management of chronic disease in the general population. Kilmer S. McCully, MD, Chief of Pathology and Laboratory Medicine, United States Department of Veterans Affairs Medical Center, VA Boston Healthcare System, Boston, MA 02132. Pioneer of the Homocysteine Theory.
Download or read book The End Of Memory written by Jay Ingram and published by HarperCollins Publishers. This book was released on 2016-01-19 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: Canada’s bestselling science writer illuminates the mysteries of Alzheimer’s disease, one of the most puzzling and debilitating conditions of the modern era It is a wicked illness that robs its victims of their memories, their ability to think clearly and, ultimately, their lives. For centuries, those afflicted by Alzheimer’s disease have been forced to suffer its devastating effects while family members sit by, watching their loved ones disappear a little more each day, until the person they used to know is gone forever. The disease was first described by pioneering German neurologist Alois Alzheimer in 1906. One hundred years and a great deal of scientific effort later, much more is known about Alzheimer’s, but it still affects millions around the world, and there is no cure in sight. In The End of Memory, award-winning science writer Jay Ingram charts the history of the disease from before it was noted by Alois Alzheimer right through to the twenty-first century, as researchers continue to search for a cure. In the spirit of Siddhartha Mukherjee’s The Emperor of All Maladies, this book is for those who want to find out the truth about an affliction that courses through families and, in some cases, inexplicably affects people early in their lives.
Download or read book The End of Alzheimer s written by Dale Bredesen and published by Penguin. This book was released on 2017-08-22 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: The instant New York Times and Wall Street Journal bestseller A groundbreaking plan to prevent and reverse Alzheimer’s Disease that fundamentally changes how we understand cognitive decline. Everyone knows someone who has survived cancer, but until now no one knows anyone who has survived Alzheimer's Disease. In this paradigm shifting book, Dale Bredesen, MD, offers real hope to anyone looking to prevent and even reverse Alzheimer's Disease and cognitive decline. Revealing that AD is not one condition, as it is currently treated, but three, The End of Alzheimer’s outlines 36 metabolic factors (micronutrients, hormone levels, sleep) that can trigger "downsizing" in the brain. The protocol shows us how to rebalance these factors using lifestyle modifications like taking B12, eliminating gluten, or improving oral hygiene. The results are impressive. Of the first ten patients on the protocol, nine displayed significant improvement with 3-6 months; since then the protocol has yielded similar results with hundreds more. Now, The End of Alzheimer’s brings new hope to a broad audience of patients, caregivers, physicians, and treatment centers with a fascinating look inside the science and a complete step-by-step plan that fundamentally changes how we treat and even think about AD.
Download or read book Advances in Research and Treatment for Alzheimer s Disease written by Samuel Barrack and published by iMedPub. This book was released on 2012-01-30 with total page 117 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alzheimer's disease (AD), is the most common form of dementia. There is no cure for the disease, which worsens as it progresses, and eventually leads to death. The cause and progression of Alzheimer's disease are not well understood. Research indicates that the disease is associated with plaques and tangles in the brain. Current treatments only help with the symptoms of the disease. There are no available treatments that stop or reverse the progression of the disease. As of 2012, more than 1000 clinical trials have been or are being conducted to find ways to treat the disease, but it is unknown if any of the tested treatments will work. Because AD cannot be cured and is degenerative, the sufferer relies on others for assistance. The role of the main caregiver is often taken by the spouse or a close relative. Alzheimer's disease is known for placing a great burden on caregivers; the pressures can be wide-ranging, involving social, psychological, physical, and economic elements of the caregiver's life. In developed countries, AD is one of the most costly diseases to society. Research is the only hope to present and future patients and families suffering from this devastating disorder. This book compiles some of the most interesting articles on Alzheimer's disease published by PLoS journals lately: from epidemiology and prevention to management and treatment.
Download or read book Alzheimer s Disease Decoded The History Present And Future Of Alzheimer s Disease And Dementia Second Edition written by Ronald Sahyouni and published by World Scientific. This book was released on 2021-12-23 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book aims to present, educate and inform individuals about Alzheimer's disease in a comprehensive manner. Its scope ranges from the discovery of the disease, epidemiology and basic biological principles underlying it, to advanced stem cell therapies used in the treatment of Alzheimer's. It adopts a 'global' perspective on Alzheimer's disease, and include epidemiological data and science from countries around the world.Alzheimer's disease is a rapidly growing problem seen in every country around the world. This is the first and only comprehensive book to cover Alzheimer's disease, and includes the most updated literature and scientific progress in the field of dementia and Alzheimer's disease research.Most books on the market that focus on Alzheimer's disease are targeted at caregivers as practical advice on how to deal with loved ones with the disease. This book instead is a comprehensive and popular science book that can be read by anyone with an interest in learning more about the disease.Dr Jefferson Chen MD, PhD, co-author, participated in the world's first surgical clinical trial using shunts to treat Alzheimer's disease. His first-hand involvement in a clinical trial for patients with Alzheimer's disease and experience treating Normal Pressure Hydrocephalus (NPH) which is commonly misdiagnosed as Alzheimer's disease lends a unique perspective.This book with appeal to a wide audience, regardless of their scientific or educational background.
Download or read book Alzheimer s Disease written by Peggy J. Parks and published by Referencepoint Press. This book was released on 2009 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alzheimer's is a devastating disease that literally causes the brain to waste away, and it is always fatal. Through objective interviews, primary sources, and full-color illustrations, this title examines: How Does Alzheimer's Disease Affect the Brain? What Causes Alzheimer's Disease? Who Suffers from Alzheimer's Disease? Will Research Prevent or Cure Alzheimer's Disease?
Download or read book The Alzheimer s Project written by John Hoffman and published by Hachette UK. This book was released on 2009-05-12 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: This companion book to the HBO Documentary Films series explores the cutting-edge research on Alzheimer's disease that is creating new hope for the future. Alzheimer's disease is the second most-feared illness in America, following cancer. It affects as many as 5 million Americans, a number that could soar to 16 million by 2050. It is estimated that, unless effective preventions are discovered, 10 million baby boomers will eventually develop this irreversible and devastating brain disorder. Until recently, medical news on Alzheimer's disease was not comforting. But in the past few years, advances in many scientific areas -- from diagnostic imaging to genetic analysis -- have led to an explosion of knowledge with implications for treatment and prevention. This is an exciting time of discovery in Alzheimer's research. Through The Alzheimer's Project film series, HBO Documentary Films illuminates the vital breakthroughs occurring in the field. One of the central films in this series, Momentum in Science, brings us inside the laboratories and clinics of the nation's top scientists and physicians who are clearing the path to a deeper understanding of Alzheimer's disease. By capturing the exhilaration of these scientists and casting light on their groundbreaking discoveries, the film seeks to bring a wider understanding of the disease and new hope for future treatment. This book offers an even closer look at the advances of this scientific frontier. It investigates the complex cascade of events that occurs inside the brain when someone has Alzheimer's disease and shows how scientists are working to interrupt this process and ultimately prevent the disease. In accessible prose, it examines specific evidence of momentous progress, from the triumphant discovery of the unique role of the beta-amyloid and tau proteins, to the use of PET scans to track changes in the brain and the analyses of cerebrospinal fluid to identify biomarkers that will help us predict who will develop the disease in the future. It also looks at current drug development and at what we can do as individuals to potentially reduce our risk of developing the disease. The Alzheimer's Project: Momentum in Science is a fascinating story of scientific discovery that shows what recent breakthroughs might mean for improving our chances of remaining cognitively vital throughout a long life.
Download or read book The Alzheimer s Epidemic written by Danton O'Day and published by . This book was released on 2013-07 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: The "Alzheimer's Epidemic" has begun. As the number of aged individuals worldwide continues to grow the epidemic will continue unabated. Alzheimer's disease will affect one in three families. In addition to the devastating implications of this epidemic to Alzheimer's sufferers, their families and caregivers, the economic costs to society will be enormous. Around the world governments are struggling with ways to deal with this unrelenting tide that will soon be a medical tsunami that will challenge many societies' ability to cope. At the front of this attempt to stem the tide are biomedical researchers worldwide who are working diligently to understand the causes of Alzheimer's, which will allow them to formulate ways to slow the progression of the disease and someday stop it from occurring. In 16 chapters with over 100 original full color figures, this book looks in depth at this "Alzheimer's Epidemic" by focusing on the causes and the search for a cure. Other books have dealt in detail with the symptoms of the disease and how to care for those suffering with the disease. This book is significantly different from those that have gone before. The content is gleaned from original research and reviews including recent international meetings. The authors' strong science background and research on proteins linked to the disease has allowed him to look at Alzheimer's disease from a wide base of knowledge which leads to some new insights into the origins and future of the disease. This book sets the stage for an in-depth understanding of what is being done and where research is going in the quest to understand the causes and find a cure for an unrelenting disease that paves the way to dementia for those it affects.
Download or read book Alzheimer s Disease written by Jonathan D. Turner and published by . This book was released on 1996 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alzheimer's Disease is a progressive neurodegenerative disorder of late life with devastating consequences for the afflicted and their carers and poses one of the major challenges to medical research. Until recently, little hope of effective therapies capable of slowing the disease process or preventing its occurrence was apparent. With recent advances in the genetics and molecular biology of the disease processes and the demonstration of the involvement of multiple aetiological factors, however, real chances are now appearing for the identification of preventive drugs. In this discussion, experts from disciplines ranging from molecular genetics to the clinic provide review and novel data concerning the aetiology of AD and the establishment of drugfinding screening methods.
Download or read book Alzheimer s Disease Decoded The History Present and Future of Alzheimer s Disease and Dementia 2nd Edition written by Ronald Sahyouni and published by World Scientific Publishing Company. This book was released on 2021-12-23 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book aims to present, educate and inform individuals about Alzheimer's disease in a comprehensive manner. Its scope ranges from the discovery of the disease, epidemiology and basic biological principles underlying it, to advanced stem cell therapies used in the treatment of Alzheimer's. It adopts a "global" perspective on Alzheimer's disease, and include epidemiological data and science from countries around the world. Alzheimer's disease is a rapidly growing problem seen in every country around the world. This is the first and only comprehensive book to cover Alzheimer's disease, and includes the most updated literature and scientific progress in the field of dementia and Alzheimer's disease research. Most books on the market that focus on Alzheimer's disease are targeted at caregivers as practical advice on how to deal with loved ones with the disease. This book instead is a comprehensive and popular science book that can be read by anyone with an interest in learning more about the disease. Dr Jefferson Chen MD, PhD, co-author, participated in the world's first surgical clinical trial using shunts to treat Alzheimer's disease. His first-hand involvement in a clinical trial for patients with Alzheimer's disease and experience treating Normal Pressure Hydrocephalus (NPH) which is commonly misdiagnosed as Alzheimer's disease lends a unique perspective. This book with appeal to a wide audience, regardless of their scientific or educational background.
