Download or read book An Epithermal Neutron Beam from the MURR and from an Accelerator Source Compared to the Beam at the BMRR written by and published by . This book was released on 1992 with total page 8 pages. Available in PDF, EPUB and Kindle. Book excerpt: An ideal neutron beam for BNCT is a beam of epithermal neutrons, forward directed, and free of gamma rays and thermal and fast neutrons. Three neutron beams were evaluated, and compared: (1) the operating Brookhaven Medical Research Reactor (BMRR) epithermal beam, (2) the designed Missouri University Research Reactor (MURR) epithermal beam, and (3) the accelerator-based epithermal neutron beam designed by Wu. These neutron beams were compared with respect to the neutron spectra, neutron and gamma fluxes and doses, and beam directionality. The epithermal neutron beams were inter-compared for different beam parameters in air at the irradiation point. The BMRR beam has the highest neutron plus gamma doses per epithermal neutron among these neutron beams but is satisfactory for patient trials by BNCT at the present time. The RBE dose delivered to the normal brain reaches the tolerance dose limit before the skin RBE dose reaches its limit, so the skin dose can be controlled under the limit. Generally speaking, a treatment can be completed in 54 minutes using the BMRR beam for irradiation at a full-power operation of the reactor. The MURR beam has better beam parameters, including lower neutron and gamma doses per epithermal neutron, higher in intensity, and also directed. The irradiation time could be 5 minutes to complete a treatment. The accelerator-based neutron beam which has shown promising beam parameters similar to the BMRR beam could be a choice in hospitals. However, a complete system at the required power has not yet been demonstrated.
Download or read book An Epithermal Neutron Beam from the MURR and from and Accelerator Source Compared to the Beam at the BMRR written by and published by . This book was released on 1992 with total page 8 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Energy Research Abstracts written by and published by . This book was released on 1993 with total page 600 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Advances in Neutron Capture Therapy written by R.F. Barth and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 776 pages. Available in PDF, EPUB and Kindle. Book excerpt: Binary systems for the treatment of cancer potentially are among the most attractive of the new therapeutic modalities that currently are under investigation. The basicconcept is to selectivelydestroy malignantcells whileconcomitantlysparing normal tissue. Neutron capture therapy (NCT) is the binary system that has been the subject of the Fifth International Symposium on Neutron Capture Therapy, which was held September13-17, 1992, in Columbus, Ohio, undertheauspicesoftheInternational Society for Neutron Capture Therapy. Its objective was to bring together researchers from throughout the world and to provide a forum at which they could present the latest advances in the development of Neutron capture therapy. Neutron capture therapy has largely, but not exclusively, focused on the use of boron-10 as the target nuclide. Boron neutron capture therapy (BNCT) is based on the nuclear reaction that occurs when the stable isotope, boron-10, absorbs low-energy non ionizing thermal neutrons to yield alphaparticles and recoiling lithium-7 nuclei. The size and energy of these high linear energy transfer (LET) particles result in their being confined largely to the cells in which the capture reaction occurs. For BNCT to be successful, a sufficient numberof I~atoms mustbe localized within neoplastic cells, and enough thermal neutrons must be delivered and absorbed by the I~ to produce a lethal 1~(n,QVLi reaction. Two major problems must be surmounted.
Download or read book Neutron Beam Design Development and Performance for Neutron Capture Therapy written by Otto K. Harling and published by Springer Science & Business Media. This book was released on 2013-03-08 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: For this Workshop, the organizers have attempted to invite experts from all known centers which are engaged in neutron beam development for neutron capture therapy. The Workshop was designed around a series of nineteen invited papers which dealt with neutron source design and development and beam characterization and performance. Emphasis was placed on epithermal beams because they offer clinical advantages and are more challenging to implement than thermal beams. Fission reactor sources were the basis for the majority of the papers; however three papers dealt with accelerator neutron sources. An additional three invited papers provided a summary of clinical results of Ncr therapy in Japan between 1968 and 1989 and overviews of clinical considerations for neutron capture therapy and of the status of tumor targeting chemical agents for Ncr. Five contributed poster papers dealing with NCT beam design and performance were also presented. A rapporteurs' paper was prepared after the Workshop to attempt to summarize the major aspects, issues, and conclusions which resulted from this Workshop. Many people contributed to both the smooth functioning of the Workshop and to the preparation of these proceedings. Special thanks are reserved for Ms. Dorothy K.
Download or read book Progress in Neutron Capture Therapy for Cancer written by B.J. Allen and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 641 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite the many advances made in the diagnosis and therapy of cancer, the mortality rate is still about half that of the incidence rate. However, the odds are not evenly distributed. Prognosis for some cancers is good, but for others, few patients will survive 12 months. This latter group of cancers is characterised by a proclivity to disseminate malignant cells in the host organ. The degree of surgery possible may be limited by the critical nature of the organ, and chemotherapy and radiotherapy are of palliative value only. In some cases systemic metastases occur, but in other cases, failure to achieve local control results in death. First among these cancers are the high grade brain tumours, astrocytoma 3,4 and glioblastoma multiforme. Local control of these tumours should lead to cure. Other cancers melanoma metastatic to the brain, for which a useful palliative therapy is not yet available, and pancreatic cancer for which localised control at an early stage could bring about improved prognosis. Patients with these cancers have little grounds for hope. Our primary objective is to reverse this situation with Neutron Capture Therapy (NCT). The purpose of this fourth symposium is to hasten the day whereby patients with these cancers can reasonably hope for substantial remissions. The first symposium on NCT was held in Boston in 1983, followed by Tokyo in 1985 and Bremen, Germany in 1988.
Download or read book Government Reports Announcements Index written by and published by . This book was released on 1993 with total page 658 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Government Reports Annual Index written by and published by . This book was released on 1993 with total page 1290 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sections 1-2. Keyword Index.--Section 3. Personal author index.--Section 4. Corporate author index.-- Section 5. Contract/grant number index, NTIS order/report number index 1-E.--Section 6. NTIS order/report number index F-Z.
Download or read book Proceedings of the ASME JSME 4th International Conference on Nuclear Engineering 1996 written by Atam S. Rao and published by . This book was released on 1996 with total page 642 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Cumulated Index Medicus written by and published by . This book was released on 1991 with total page 1472 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book A 1000 GeV on 1000 GeV Proton proton Colliding Beam Facility written by Fermi National Accelerator Laboratory and published by . This book was released on 1976 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Proceedings of the 1998 ANS Radiation Protection and Shielding Division Topical Conference written by and published by . This book was released on 1998 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Solar and Interplanetary Dynamics written by M. Dryer and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 543 pages. Available in PDF, EPUB and Kindle. Book excerpt: Informal discussions in 1977 among a number of scientists asso ciated with solar and interplanetary physics revealed a need for a dialogue between the two often-divergent groups. It was clear that the latter group was dependent essentially on the sun for its raison d'etre. On the other hand it was also clear that the former group could benefit in its search for insight vis-a-vis solar activity by looking beyond the shell of the inner corona. Needless to add that the combined solar/interplanetary topic is relevant to astrophysics when one considers stellar winds and binary star flows. It was felt, there fore, that a symposium was essential to bring together, for the first time, leading solar and interplanetary physicists from the interna tional community to discuss and record herein their own research. The fundamental physical processes underlying our own capricious star's activity can be understood only by the coupling of solar and interplan etary topics in an intimate observational and theoretical structure. This book, intended for active research scientists and advanced grad uate students, is an important step in this direction. The background of solar and interplanetary dynamics is provided in Part I (The Life History of Coronal Structures and Fields) and Part II (Coronal and Interplanetary Responses to Long Time Scale Phenomena).
Download or read book The 1996 Baseline Environmental Management Report Report written by and published by . This book was released on 1996 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Workbook of Atmospheric Dispersion Estimates written by D. Bruce Turner and published by CRC Press. This book was released on 1994-05-05 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: This completely updated and revised Second Edition of the popular Workbook of Atmospheric Dispersion Estimates provides an important foundation for understanding dispersion modeling as it is being practiced today. The book and accompanying diskette will help you determine the impacts of various sources of air pollution, including the effects of wind and turbulence, plume rise, and Gaussian dispersion and its limitations. Information is shown in summary graphs as well as in equations. The programs included on the diskette allow you to "get the feel" for the results you'll obtain through the input of various combinations of parameter values. The sensitivity of data to various parameters can be easily explored by changing one value and seeing the effect on the results. The book presents 37 example problems with solutions to show the estimation of atmospheric pollutant concentrations for many situations.
Download or read book Fresh from the Farm 6pk written by Rigby and published by . This book was released on 2006 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Introduction to Digital Filtering in Geophysics written by O. Kulhánek and published by Elsevier. This book was released on 2012-12-02 with total page 181 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction to Digital Filtering in Geophysics
