Download or read book Amino Acid Derivatives written by G. C. Barrett and published by Oxford University Press on Demand. This book was released on 1999 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many successful syntheses of homochiral organic compounds use an amino acid derivative as a starting point. Such syntheses are not confined to peptides as targets; peptide synthesis strategies have been narrowed down to a few well-defined protocols (and these are not covered in this book).Outside the peptide field, many non-routine syntheses have been established that give the intended products in which the structural features of the starting amino acid are barely recognisable. This book is a laboratory guide that covers the early stages of syntheses under these headings, whichinvariably call for modifications to the functional groups of readily-available L-amino acids. It will therefore give invaluable guidance to the preparation of amino acid derivatives to be used not only in these broad area of synthesis but also in amino acid analysis. Synthetic work with aminoacids carried out by new users and by experienced chemists and other scientists, will be supported by the detailed practical protocols and background information provided in this book.
Download or read book The Biochemistry of Alkaloids written by Trevor Robinson and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 159 pages. Available in PDF, EPUB and Kindle. Book excerpt: The alkaloids were of great importance to mankind for centuries, long before they were recognized as a chemical class. The influence they have had on literature is hinted at by some of the quotations I have used as chapter headings. Their in fluence on folklore and on medicine has been even greater. The scientific study of alkaloids may be said to have begun with the isolation of morphine by SERTURNER in 1804. Since that time they have remained of great interest to chemists, and now in any month there appear dozens of publications dealing with the isolation of new alkaloids or the determination of the structures of previously known ones. The area of alkaloid biochemistry, in comparison, has received little attention, and today is much less developed. There is a certain amount of personal arbitrariness in defining "biochemistry", as there is in defining "alkaloid", and this arbitrariness is doubtless compounded by the combination. Nevertheless, it seems to me that in any consideration of the bio chemistry of a group of compounds three aspects are always worthy of attention pathways of biosynthesis, function or activity, and pathways of degradation. For the alkaloids, treatment of these three aspects is necessarily lopsided. Much has been learned about routes of biosynthesis, but information on the other aspects is very scanty. It would be possible to enter into some speculation regarding the biosyn thesis of all the more than 1,000 known alkaloids.
Download or read book The Synthesis of Certain Amino Acid Derivatives written by Alfred Edward Brown and published by . This book was released on 1940 with total page 94 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Total Chemical Synthesis of Proteins written by Ashraf Brik and published by John Wiley & Sons. This book was released on 2021-06-08 with total page 626 pages. Available in PDF, EPUB and Kindle. Book excerpt: How to synthesize native and modified proteins in the test tube With contributions from a panel of experts representing a range of disciplines, Total Chemical Synthesis of Proteins presents a carefully curated collection of synthetic approaches and strategies for the total synthesis of native and modified proteins. Comprehensive in scope, this important reference explores the three main chemoselective ligation methods for assembling unprotected peptide segments, including native chemical ligation (NCL). It includes information on synthetic strategies for the complex polypeptides that constitute glycoproteins, sulfoproteins, and membrane proteins, as well as their characterization. In addition, important areas of application for total protein synthesis are detailed, such as protein crystallography, protein engineering, and biomedical research. The authors also discuss the synthetic challenges that remain to be addressed. This unmatched resource: Contains valuable insights from the pioneers in the field of chemical protein synthesis Presents proven synthetic approaches for a range of protein families Explores key applications of precisely controlled protein synthesis, including novel diagnostics and therapeutics Written for organic chemists, biochemists, biotechnologists, and molecular biologists, Total Chemical Synthesis of Proteins provides key knowledge for everyone venturing into the burgeoning field of protein design and synthetic biology.
Download or read book Organic Corrosion Inhibitors written by Chandrabhan Verma and published by John Wiley & Sons. This book was released on 2021-09-11 with total page 530 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides comprehensive coverage of organic corrosion inhibitors used in modern industrial platforms, including current developments in the design of promising classes of organic corrosion inhibitors Corrosion is the cause of significant economic and safety-related problems that span across industries and applications, including production and processing operations, transportation and public utilities infrastructure, and oil and gas exploration. The use of organic corrosion inhibitors is a simple and cost-effective method for protecting processes, machinery, and materials while remaining environmentally acceptable. Organic Corrosion Inhibitors: Synthesis, Characterization, Mechanism, and Applications provides up-to-date coverage of all aspects of organic corrosion inhibitors, including their fundamental characteristics, synthesis, characterization, inhibition mechanism, and industrial applications. Divided into five sections, the text first covers the basics of corrosion and prevention, experimental and computational testing, and the differences between organic and inorganic corrosion inhibitors. The next section describes various heterocyclic and non-heterocyclic corrosion inhibitors, followed by discussion of the corrosion inhibition characteristics of carbohydrates, amino acids, and other organic green corrosion inhibitors. The final two sections examine the corrosion inhibition properties of carbon nanotubes and graphene oxide, and review the application of natural and synthetic polymers as corrosion inhibitors. Featuring contributions by leading researchers and scientists from academia and industry, this authoritative volume: Discusses the latest developments and issues in the area of corrosion inhibition, including manufacturing challenges and new industrial applications Explores the development and implementation of environmentally-friendly alternatives to traditional toxic corrosion inhibitors Covers both established and emerging classes of corrosion inhibitors as well as future research directions Describes the anticorrosive mechanisms and effects of acyclic, cyclic, natural, and synthetic corrosion inhibitors Offering an interdisciplinary approach to the subject, Organic Corrosion Inhibitors: Synthesis, Characterization, Mechanism, and Applications is essential reading for chemists, chemical engineers, researchers, industry professionals, and advanced students working in fields such as corrosion inhibitors, corrosion engineering, materials science, and applied chemistry.
Download or read book Solution and Solid Phase Studies of Amino Acid Derivatives written by Charles W. Lugar (III.) and published by . This book was released on 1997 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Medicinal Herbs in Primary Care written by Jean M. Bokelmann and published by Elsevier Health Sciences. This book was released on 2021-07-20 with total page 713 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written specifically for the conventional medical healthcare provider, Medicinal Herbs in Primary Care forms an integral part of the primary care tool belt. Through a series of system-based disease tables, this unique title provides quick, authoritative guidance for the busy practitioner whose patient is requesting guidance on medicinal herbs. The disease tables are supported by herbal monographs that provide expanded details of the available preclinical and clinical evidence laid out in a system-based sequence. Together with the section on herbal basics, this practical reference contains the information today’s medical healthcare providers need to develop familiarity with and confidence in the prescription of medicinal herbs. Provides quick answers and evidence-based prescribing guidance for medicinal herbs while also addressing complexities and co-morbidities in patient care. Features 48 system-based disease tables that identify herbs based on strength of evidence and indicate the scope of potential benefits for other conditions the patient may have. Includes 55 monographs for the most common medicinal herbs, with safety and precaution guidelines, summaries of preclinical and clinical trials, chemical constituents and actions, and prescription options for each. Contains an introductory section on the basics of medicinal herbs that dispels common misconceptions regarding herbal medicine. Discusses key topics such as herb-drug interactions, and includes information on SARS-COV-2 where appropriate. Uses typical medical abbreviations throughout for ease of use, and provides a glossary of terms for non-medical and alternative health care providers. Helps conventional medical practitioners partner with patients to determine safe herbal options when appropriate, and ensure safety and efficacy of herbal use.
Download or read book Chemistry and Biochemistry of the Amino Acids written by Graham Barrett and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 694 pages. Available in PDF, EPUB and Kindle. Book excerpt: Amino acids are featured in course syllabuses and in project and research work over a wide spectrum of subject areas in chemistry and biology. Chemists and biochemists using amino acids have many common needs when they turn to the literature for comprehensive information. Among these common interests, analytical studies, in particular, have undergone rapid development in recent years. All other chemical and biochemical aspects of amino acids - synthesis, properties and reactions, preparation of derivatives for use in peptide synthesis, racemization and other fundamental mechanistic knowledge - have been the subject of vigorous progress. This book offers a thorough treatment of all these developing areas, and is structured in the belief that biochemists, physiologists and others will profit from access to information on topics such as the physical chemistry of amino acid solutions, as well as from thorough coverage of amino acid metabolism, biosynthesis and enzyme inhibition; and that chemists will find relevant material in biological areas as well as in the analysis, synthesis and reactions of amino acids.
Download or read book Fluorinated Amino Acid Derivatives written by Darko Butina and published by . This book was released on 1975 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Enzymatic and Chemical Synthesis of Nucleic Acid Derivatives written by Jesús Fernández Lucas and published by John Wiley & Sons. This book was released on 2019-04-29 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: A review of innovative tools for creative nucleic acid chemists that open the door to novel probes and therapeutic agents Nucleic acids continue to gain importance as novel diagnostic and therapeutic agents. With contributions from noted scientists and scholars, Enzymatic and Chemical Synthesis of Nucleic Acid Derivatives is a practical reference that includes a wide range of approaches for the synthesis of designer nucleic acids and their derivatives. The book covers enzymatic (including chemo-enzymatic) methods, with a focus on the synthesis and incorporation of modified nucleosides. The authors also offer a review of innovative approaches for the non-enzymatic chemical synthesis of nucleic acids and their analogs and derivatives, highlighting especially challenging species. The book offers a concise review of the methods that prepare novel and heavily modified polynucleotides in sufficient amount and purity for most clinical and research applications. This important book: -Presents a timely and topical guide to the synthesis of designer nucleic acids and their derivatives -Addresses the growing market for nucleotide-derived pharmaceuticals used as anti-infectives and chemotherapeutic agents, as well as fungicides and other agrochemicals. -Covers novel methods and the most recent trends in the field -Contains contributions from an international panel of noted scientistics Written for biochemists, medicinal chemists, natural products chemists, organic chemists, and biotechnologists, Enzymatic and Chemical Synthesis of Nucleic Acid Derivatives is a practice-oriented guide that reviews innovative methods for the enzymatic as well as non-enzymatic synthesis of nucleic acid species.
Download or read book Amino Acid Derivatives of Selected Steroids written by and published by . This book was released on 1962 with total page 98 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Amino Acids and Derivatives written by B. J. Miflin and published by Elsevier. This book was released on 2014-05-10 with total page 687 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Biochemistry of Plants: A Comprehensive Treatise, Volume 5: Amino Acids and Derivatives provides information pertinent to the fundamental aspects of plant biochemistry relating to the metabolism of amino acids with emphasis on amino acids present in proteins. This book discusses the metabolism of sulfur and nitrogen from the inorganic sources available to plants through their incorporation into organic compounds. Organized into 17 chapters, this volume begins with an overview of some aspects of the biochemistry of symbiotic nitrogen fixation. This text then examines the ultrastructure and metabolism of the developing nodule with particular emphasis on interactions between the host legumes and the bacterial symbiont. Other chapters consider the characteristics of the enzymes involved in nitrate and nitrite reduction. The final chapter deals with the essential roles of amino acids and other soluble nitrogenous compounds in plant metabolism. This book is a valuable resource for plant biochemists, neurobiochemists, molecular biologists, senior graduate students, and research workers.
Download or read book Synthesis of B amino Acid Derivatives written by Brad E. Sleebs and published by . This book was released on 2004 with total page 640 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chapter 4 outlines the utilisation of oxazinanones in a series of alkylations and hydroxylations to produce {460},U+00dd-disubstituted-U+00dd-amino acids. The enolate chemistry performed with the oxazinanones occurred in a diastereoselective fashion. Such is the versatility of the chemistry, both diastereopure N-methyl and N-H {460},U+00dd-disubstituted-U+00dd-amino acids can be obtained. The following chapter details the experimental procedures and data for the synthesis of these important amino acid residues.
Download or read book Complexation of Amino acid Derivatives Using Macrocyclic Receptors written by David John Smith and published by . This book was released on 1996 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Pharmaceutical Biocatalysis written by Peter Grunwald and published by CRC Press. This book was released on 2019-11-07 with total page 567 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides an insight into the future strategies for commercial biocatalysis with a focus on sustainable technologies, together with chemoenzymatic and biotechnological approaches to synthesize various types of approved and new active pharmaceutical ingredients (APIs) via proven and latest synthetic routes using single-step biocatalytic or enzyme cascade reactions. Many of these drugs act as enzyme inhibitors, as discussed in a chapter with a variety of examples. The targeted enzymes are involved in diseases such as different cancers, metastatic and infectious diseases, osteoporosis, and cardiovascular disorders. The biocatalysts employed for API synthesis include hydrolytic enzymes, alcohol dehydrogenases, laccases, imine reductases, reductive aminases, peroxygenases, cytochrome P450 enzymes, polyketide synthases, transaminases, and halogenases. Many of them have been improved with respect to their properties by engineering methods. The book discusses the syntheses of drugs, including alkaloids and antibiotics, non-ribosomal peptides, antimalarial and antidiabetic drugs, prenylated xanthones, antioxidants, and many important (chiral) intermediates required for the synthesis of pharmaceuticals.
Download or read book Handbook of Neuro Oncology Neuroimaging written by Herbert B. Newton and published by Academic Press. This book was released on 2022-08-21 with total page 1022 pages. Available in PDF, EPUB and Kindle. Book excerpt: With treatment approaches and the field of neuro-oncology neuroimaging changing rapidly, this third edition of the Handbook of Neuro-Oncology Neuroimaging is very relevant to those in the field, providing a single-source, comprehensive, reference handbook of the most up-to-date clinical and technical information regarding the application of neuroimaging techniques to brain tumor and neuro-oncology patients. This new volume will have updates on all of the material from the second edition, and in addition features several new important chapters covering diverse topics such as imaging for the use of Laser Interstitial Thermal Therapy, advanced imaging techniques in radiation therapy, therapeutic treatment fields, response assessment in clinical trials, surgical planning of neoplastic disease of the spine, and more. Sections first overview neuro-oncological disorders before delving into the physics and basic science of neuroimaging and great focus on CT and MRI. The book then focuses on advances in the neuroimaging of brain tumors and neuroimaging of specific tumor types. There is also discussion of neuroimaging of other neuro-oncological syndromes. This book will serve as a resource of background information to neuroimaging researchers and basic scientists with an interest in brain tumors and neuro-oncology. - Summarizes translational research on brain imaging for brain tumors - Discusses limitations of neuroimaging for diagnosis and treatment - Presents advanced imaging technologies, including CT, MRI, and PET - Contains new coverage on Laser Interstitial Thermal Therapy, radiation therapy, clinical trials, and more
Download or read book Plant Adaptation to Environmental Change written by Naser A. Anjum and published by CABI. This book was released on 2014-01-10 with total page 345 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plants constantly cope with unfavourable ecosystem conditions, which often prevent them reaching their full genetic potential in terms of growth, development and productivity. This book covers plants' responses to these environmental changes, namely, the modulation of amino acids, peptides and amines to combat both biotic and abiotic stress factors. Bringing together the most recent developments, this book is an important resource for researchers and students of crop stress and plant physiology.
