Download or read book Alpha Keto Acid Dehydrogenase Complexes written by M.S. Patel and published by Birkhäuser. This book was released on 2012-12-06 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: Found in all organisms, the alpha-keto acid dehydrogenase complexes have central roles in cellular metabolism and are major sites of regulation. The understanding of the organization, function and regulation of these quintessential multienzyme complexes has been greatly advanced by studies employing molecular biology and biophysical techniques. Although these enzyme systems have some features in common, their diversity in fulfilling unique organism - or tissue - specific roles is truly amazing. These systems have medical importance in areas ranging from defects in regulation (linked to diabetes, heart disease, obesity, nutrition defects), to inherited diseases (inborn errors, maple syrup urine disease) to acquired immune diseases (primary biliary cirrhosis). This book brings together wide-ranging recent findings on the structure(function relationships, gene regulation, and genetic defects of the alpha-keto acid dehydrogenase complexes, namely the pyruvate dehydrogenase, alpha-ketoglutarate dehydrogenase and the branched-chain alpha-keto acid dehydrogenase complexes. A wide variety of experimental approaches together with new results presented in this book should serve as a resource for beginning to established investigators in the field as well as scientists who are interested in mitochondria, dehydrogenases, kinases, phosphatases, lipoic acid, thiamine pyrophosphate, and enzyme complexes.

Download or read book Alpha keto Acid Dehydrogenase Complexes written by Thomas E. Roche and published by . This book was released on 1989 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Branched chain Amino Acids written by Robert Allison Harris and published by Academic Press. This book was released on 2000 with total page 587 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume 324 of Methods in Enzymology supplements Volume 166. It includes genetic information (cloning, gene expression) and information on human genetic diseases not available when Volume 166 was published.

Download or read book Structural and mechanistic studies of alpha keto acid dehydrogenase complexes written by Jimmy Harold Collins and published by . This book was released on 1977 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Gene protein Relationships of Bacterial alpha keto Acid Dehydrogenase Complexes written by David Langley and published by . This book was released on 1976 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Inborn Metabolic Diseases written by K. Tada and published by Springer Science & Business Media. This book was released on 2013-03-14 with total page 421 pages. Available in PDF, EPUB and Kindle. Book excerpt: Each disease-related chapter begins with a detailed description of the patient and the delineating symptoms used for establishing the diagnosis and differential diagnosis. The highly detailed figures illustrate the metabolic derangement in a uniform way, together with essential aspects of the genetics involved, thus affording clarification and better understanding of the treatment. Topics covered range from general aspects such as the clinical approach, emergency treatment, diagnostic procedures, and psychosocial care for the child and the family, to specific discussions of new modes of treatment, including liver, bone marrow transplantation and somatic gene therapy.

Download or read book Lipoic Acid written by Mulchand S. Patel and published by CRC Press. This book was released on 2008-03-17 with total page 558 pages. Available in PDF, EPUB and Kindle. Book excerpt: The recognition of oxidative stress as a major factor in health, aging, and disease has led to a surge in research aimed at uncovering effective countermeasures in the form of antioxidants. Unique in its two-fold protective function, alpha-lipoic acid has drawn unprecedented interest as a coenzyme in mitochondrial energy metabolism and as an antiox

Download or read book A lfa keto Acid Dehydrogenase Complexes XVIII Subunit Composition of the Escherichia Coli Pyruvate Dehydrogenase Complex written by Michael H. Eley and published by . This book was released on 1972 with total page 15 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Progressive Brain Disorders in Childhood written by Juan M. Pascual and published by Cambridge University Press. This book was released on 2017-04-20 with total page 507 pages. Available in PDF, EPUB and Kindle. Book excerpt: A review of childhood neurodegenerative and other progressive but non-degenerative disorders to guide their diagnosis and management.

Download or read book A lfa keto Acid Dehydrogenase Complexes XX A Kinetic Study of the Pyruvate Dehydrogenase Complex from Bovine Kidney written by C. Stanley Tsai and published by . This book was released on 1973 with total page 5 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Heterogeneity of Cancer Metabolism written by Anne Le and published by Springer. This book was released on 2018-06-26 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow cancer cells to survive and proliferate in diverse tumor microenvironments. This metabolic flexibility is different from normal cellular metabolic processes and leads to heterogeneity in cancer metabolism within the same cancer type or even within the same tumor. In this book, we delve into the complexity and diversity of cancer metabolism, and highlight how understanding the heterogeneity of cancer metabolism is fundamental to the development of effective metabolism-based therapeutic strategies. Deciphering how cancer cells utilize various nutrient resources will enable clinicians and researchers to pair specific chemotherapeutic agents with patients who are most likely to respond with positive outcomes, allowing for more cost-effective and personalized cancer therapeutic strategies.

Download or read book Plant Amino Acids written by Bijay K. Singh and published by CRC Press. This book was released on 1998-10-27 with total page 636 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covers the basic knowledge of the regulation of biosynthesis of various amino acids in plants and the application of this knowledge to the discovery of novel inhibitors of amino acid biosynthesis and for enhancing the nutritional value of plant products. Provides an exhaustive list of pathway inhibitors.

Download or read book Use of Branched Chain Alpha Keto Acid Dehydrogenase Complex for Production of Fusel Alcohols in Escherichia Coli written by Matthew John Silverman and published by . This book was released on 2010 with total page 92 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Role of Lipoic Acid in Reactions of ketoacid Dehydrogenase Complexes written by Yuh-Shyong Yang and published by . This book was released on 1987 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book A lfa keto Acid Dehydrogenase Complexes X Regulation of the Activity of the Pyruvate Dehydrogenase Complex from Beef Kidney Mitochondria by Phosphorylation and Dephosphorylation written by Tracy C. Linn and published by . This book was released on 1969 with total page 7 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book A lfa keto Acid Dehydrogenase Complexes VI Dissociation and Reconstitution of the Dihydrolipoyl Transacetylase of escherichia Coli written by Charles R. Willms and published by . This book was released on 1967 with total page 9 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Prokaryotic Metabolism and Physiology written by Byung Hong Kim and published by Cambridge University Press. This book was released on 2019-05-16 with total page 509 pages. Available in PDF, EPUB and Kindle. Book excerpt: Extensive and up-to-date review of key metabolic processes in bacteria and archaea and how metabolism is regulated under various conditions.