Download or read book Adverse Effects of Cancer Chemotherapy Anything New to Improve Tolerance and Reduce Sequelae written by Kulmira Nurgali and published by Frontiers Media SA. This book was released on 2018-06-12 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in anti-cancer chemotherapy over recent years have led to improved efficacy in curing or controlling many cancers. Some chemotherapy-related side-effects are well recognized and include: nausea, vomiting, bone marrow suppression, peripheral neuropathy, cardiac and skeletal muscle dysfunction and renal impairment. However, it is becoming clearer that some chemotherapy-related adverse effects may persist even in long term cancer survivors. Problems such as cognitive, cardiovascular and gastrointestinal dysfunction, and neuropathy may lead to substantial long term morbidity. Despite improvements in treatments to counteract acute chemotherapy-induced adverse effects, they are often incompletely effective. Furthermore, counter-measures for some acute side-effects and many potential longer term sequelae of anti-cancer chemotherapy have not been developed. Thus, new insights into prevalence and mechanisms of cancer chemotherapy-related side effects are needed and new approaches to improving tolerance and reduce sequelae of cancer chemotherapy are urgently needed. The present Research Topic focuses on adverse effects and sequelae of chemotherapy and strategies to counteract them.
Download or read book Adverse Effects of Cancer Chemotherapy Anything New to Improve Tolerance and Reduce Sequelae written by and published by . This book was released on 2018 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in anti-cancer chemotherapy over recent years have led to improved efficacy in curing or controlling many cancers. Some chemotherapy-related side-effects are well recognized and include: nausea, vomiting, bone marrow suppression, peripheral neuropathy, cardiac and skeletal muscle dysfunction and renal impairment. However, it is becoming clearer that some chemotherapy-related adverse effects may persist even in long term cancer survivors. Problems such as cognitive, cardiovascular and gastrointestinal dysfunction, and neuropathy may lead to substantial long term morbidity. Despite improvements in treatments to counteract acute chemotherapy-induced adverse effects, they are often incompletely effective. Furthermore, counter-measures for some acute side-effects and many potential longer term sequelae of anti-cancer chemotherapy have not been developed. Thus, new insights into prevalence and mechanisms of cancer chemotherapy-related side effects are needed and new approaches to improving tolerance and reduce sequelae of cancer chemotherapy are urgently needed. The present Research Topic focuses on adverse effects and sequelae of chemotherapy and strategies to counteract them.
Download or read book Stereotactic Body Radiation Therapy written by Simon S. Lo and published by Springer Science & Business Media. This book was released on 2012-08-28 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stereotactic body radiation therapy (SBRT) has emerged as an important innovative treatment for various primary and metastatic cancers. This book provides a comprehensive and up-to-date account of the physical/technological, biological, and clinical aspects of SBRT. It will serve as a detailed resource for this rapidly developing treatment modality. The organ sites covered include lung, liver, spine, pancreas, prostate, adrenal, head and neck, and female reproductive tract. Retrospective studies and prospective clinical trials on SBRT for various organ sites from around the world are examined, and toxicities and normal tissue constraints are discussed. This book features unique insights from world-renowned experts in SBRT from North America, Asia, and Europe. It will be necessary reading for radiation oncologists, radiation oncology residents and fellows, medical physicists, medical physics residents, medical oncologists, surgical oncologists, and cancer scientists.
Download or read book Diagnosing and Treating Adult Cancers and Associated Impairments written by National Academies Of Sciences Engineeri and published by National Academies Press. This book was released on 2021-11-10 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer is the second leading cause of death among adults in the United States after heart disease. However, improvements in cancer treatment and earlier detection are leading to growing numbers of cancer survivors. As the number of cancer survivors grows, there is increased interest in how cancer and its treatments may affect a person's ability to work, whether the person has maintained employment throughout the treatment or is returning to work at a previous, current, or new place of employment. Cancer-related impairments and resulting functional limitations may or may not lead to disability as defined by the U.S. Social Security Administration (SSA), however, adults surviving cancer who are unable to work because of cancer-related impairments and functional limitations may apply for disability benefits from SSA. At the request of SSA, Diagnosing and Treating Adult Cancers and Associated Impairments provides background information on breast cancer, lung cancer, and selected other cancers to assist SSA in its review of the listing of impairments for disability assessments. This report addresses several specific topics, including determining the latest standards of care as well as new technologies for understanding disease processes, treatment modalities, and the effect of cancer on a person's health and functioning, in order to inform SSA's evaluation of disability claims for adults with cancer.
Download or read book Advances in Clinical Radiology E Book 2020 written by Frank H. Miller and published by Elsevier Health Sciences. This book was released on 2020-10-13 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Clinical Radiology was established to review the year’s most important questions in clinical radiology. A distinguished editorial board, headed by Dr. Frank Miller, identifies key areas of major progress and controversy, and invites preeminent specialists to contribute original articles devoted to these topics. These insightful overviews in radiology bring concepts to a clinical level and explore their everday impact on patient care.
Download or read book Recent Advances in Nanocarriers for Pancreatic Cancer Therapy written by Prashant Kesharwani and published by Elsevier. This book was released on 2023-10-22 with total page 493 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent Advances in Nanocarriers for Pancreatic Cancer Therapy reviews thriving strategies concerning pancreatic cancer therapy, thoroughly describing the most recent developments in emerging modern drug delivery systems focused on, and derived from, nanotechnology. By providing a holistic understanding of the molecular pathways, conventional therapy and novel nanocarriers mediated drug delivery against pancreatic cancer, this work can be considered a complete package. The book offers a solution to the dissemination of data from a broad range of resources by providing an overview of the molecular pathways and conventional therapy of pancreatic cancer, the application of various nanocarriers, and more. This book equips scientists, clinicians and students to make rational treatment approaches based on nanomedicine for improving and extending the human life against pancreatic cancer. • Explains the complete journey of nanomedicine-based approaches in pancreatic cancer drug delivery from fundamental to most recent applications • Provides information about various approaches for the diagnosis and treatment of pancreatic cancer using the latest advancement in cutting-edge nanomedical technologies • Discusses the perspectives of the technologies explored to date based upon the fi ndings outlined in highly organized tables, illustrative fi gures, and fl ow charts for easy consult and comprehension
Download or read book Pharmaceutical Applications of Dendrimers written by Abhay Singh Chauhan and published by Elsevier. This book was released on 2019-11-15 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pharmaceutical Applications of Dendrimers explores the applications of dendrimers in the solubilization of hydrophobic active ingredients, drug delivery, gene delivery, imaging, diagnosis and photodynamic therapy. The book discusses the diagnostic applications of dendrimers, including their use as MRI contrast agents and in the imaging of diseased areas. In addition, the anti-inflammatory, antimicrobial and antiviral properties of PPI and PAMAM are also covered, along with a discussion on photosensitizers, such as rose Bengal and protoporphyrin IX that have been delivered using PAMAM and PPI dendrimers for the treatment of cancer. This book is an important research reference for those who want to learn more about the development of dendrimer-based solutions for drug delivery. - Explores the role of dendrimers in the design of dendritic nanoplatforms for targeted drug and gene delivery systems - Discusses the potential of dendrimers in preformulation and formulation development - Addresses both clinical and regulatory challenges in the development of dendrimer-based formulations
Download or read book Understanding Cancer written by Buddhi Prakash Jain and published by Academic Press. This book was released on 2022-01-13 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: Understanding Cancer: From Basics to Therapeutics presents both basic concepts and research prospects in the field of cancer biology. This book summarizes the fundamental aspects of cancer and presents a detailed description of molecular aspects as well as treatment and therapeutics for patients. The book is divided into three parts: the first part deals with the basics of cancer, including etiology and medical diagnosis; the second part explores the molecular mechanisms associated with cancer, focusing on cell cycle and apoptosis, cell metabolism, gene regulation, epigenetics, and stem cells; and the third part is dedicated to therapeutics, discussing chemo and radiotherapies, gene, hormone, herbal, and immunotherapies. It is a valuable resource for cancer researchers, oncologists, graduate students, and biomedical researchers who need to understand the fundamental topics related to cancer to apply to their research work or clinical setting. - Presents fundamental aspects of cancer in a didactic way to make the content easily applicable by readers - Illustrates the content through detailed images developed by the authors exclusively for the book to facilitate comprehension - Summarizes the content of each chapter with several tables and schematic diagrams for quick consult
Download or read book Bionanotechnology in Cancer written by D. Sakthi Kumar and published by CRC Press. This book was released on 2022-10-27 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt: The cancer research world is looking forward to bionanotechnology to find the best solutions for a complete cure from cancer, which is not possible with the current established treatment methods. The past decade of research on nano imaging and drug delivery in cancer has witnessed many interesting papers and reviews, but there has not been a concise resource that discusses all fields related to nano cancer research in diagnosis and drug delivery. This book fills this gap and presents the latest bionano research in cancer, focusing on nanodiagnostics and nanotherapy. The book is organized into two sections. The section on nanodiagnostics focuses on topics such as diagnostic methods in cancer-related therapy and use of radiolabeled nanoparticles, magnetic nanoparticles, acoustically reflective nanoparticles, X-ray computed tomography, and optical nanoprobes for diagnosis. The section on nanotherapy focuses on nanomaterials in chemotherapy, magnetic nanoparticles for hyperthermia against cancer, phototherapy, nanotechnology-mediated radiation therapy, nanoparticle-mediated small-RNA deliveries for molecular therapies, and theranostics. The book will serve as the gateway to enter the beautiful and elegant field of bionanoscience, which is considered the last hope for the fight against cancer and will be a highly useful resource for the students, researchers, teachers, and curious readers working in this field or related fields.
Download or read book Natural Immunomodulators Promising Therapy for Disease Management written by Vandana S. Nikam and published by Bentham Science Publishers. This book was released on 2023-05-16 with total page 441 pages. Available in PDF, EPUB and Kindle. Book excerpt: Natural Immunomodulators: Promising Therapy for Disease Management discusses the use of natural immunomodulators as a promising therapy for managing various diseases. The book begins with an introduction to the immune system and the ways in which it can be modulated. This is followed by a discussion on the various diseases and disorders associated with the immune system, including autoimmune disorders, allergies, and immune deficiency conditions. The natural sources of immunomodulators, including plants, herbs, and other natural substances is also explained along with the importance of standardizing natural immunomodulator drugs, including the methods used to ensure their quality and consistency. The book also delves into the chemistry and analytical techniques used to study immunomodulators, clinical and pre-clinical bioassays. The next couple of chapters focus on the use of natural immunomodulators in cancer, the therapy of cancer and infectious diseases. Drug delivery and the strategy and regulatory perspective for natural immunomodulators. The final 2 chapters round up the contents with information about synthetic immunomodulators and the future perspective for the use of immunomodulators in disease management. Natural Immunomodulators: Promising Therapy for Disease Management is a comprehensive guide to the use of natural immunomodulators as a therapy for various diseases, and is a valuable resource for professionals and students interested in this topic. The book is aimed at health care professionals such as medical doctors, nurses, pharmacists, and life science and nutritionist professionals, as well as students.
Download or read book Pharmaceutical Applications of Supramolecules written by Nidhi Goel and published by Springer Nature. This book was released on 2023-01-16 with total page 331 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book outlines the use of supramolecules as different pharmaceutical drugs. Supramolecular chemistry in pharmaceutical sciences is quite a young and rapidly developing field. Supramolecular assemblies might offer an alternative for existing pharmaceutical formulations, as they facilitate the improvement of physicochemical and pharmacological properties i.e., higher bioavailability, better biocompatibility and drug-targeting, fewer multidrug-resistances. This book offers an overview of the recent advances in supramolecular structures and discusses the future aspects and challenges related to the development of these molecules, providing also a perspective on how to overcome these issues. Divided into 13 chapters contributed by experts in their field, the book provides a deeper understanding of intermolecular forces playing pivotal roles in mediating the interactions between chemical molecules and biological systems by focusing on different applications of supramolecular compounds. In this book, readers will find valuable insights into the preparation of supramolecules and the latest research and development trends of supramolecules as anticancer drugs, including liquid-crystalline supramolecular assemblies, and as antimicrobial, antiviral, anti-inflammatory and cardiovascular drugs. Particular attention is given to the application of supramolecules in the fields of biomedicine, bioimaging, and vaccine development. Given its breadth, this book will appeal to a wide readership from researchers and students interested in these fields to professionals in the pharma industry.
Download or read book Selected Papers from the 9th Greek Conference of Biochemistry and Physiology of Exercise written by Vassilis Mougios and published by MDPI. This book was released on 2021-04-14 with total page 116 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains selected papers from the 9th annual conference of the Hellenic Society of Biochemistry and Physiology of Exercise (2019). Exercise biochemistry and exercise physiology are two closely related sport sciences that examine how muscle activity alters the way our bodies (and those of other animals) function at the levels of molecules, cells, organs, and whole body. Included in the book is original research on biochemical and physiological adaptations of children, adolescents, and adults to exercise training; on the use of biochemical and physiological tests to assess sport performance; and on how exercise can fight disease.
Download or read book Natural Products and Human Diseases written by Amirhossein Sahebkar and published by Springer Nature. This book was released on 2022-01-03 with total page 546 pages. Available in PDF, EPUB and Kindle. Book excerpt: Natural products have a long history of use as folk medicines in several systems of traditional medicine. Extensive evidence from modern pharmacological studies has confirmed traditional applications, and unveiled the vast potential of naturally occurring compounds, particularly plant-derived phytochemicals, in the management of chronic human diseases. The past decade has witnessed a surge of findings from randomized controlled trials testifying the safety and efficacy of natural products as adjuncts or alternatives to standard-of-care medications for several illnesses. Biomolecular studies have unveiled hundreds of cellular and molecular targets for phytochemicals including key transcription factors, receptors, enzymes, hormones, neurotransmitters, cytokines, lipids, and non-coding RNAs. Extensive research on the preventative and therapeutic effects of natural products necessitates regular updating of the literature as to the developing potential roles of these compounds in different human diseases. This new book provides an overview of the current pharmacological and clinical features of natural products, and the role of phytopharmaceutical compounds in health and diseases. Chapters cover a wide scope, from cancers, to chronic and age-related disorders, and are written by leading international subject experts. Collectively, chapters will provide useful insights on the regulatory effects of phytochemicals and nutraceuticals on pathogenic molecular signatures associated with pathologies, disease biomarkers, and aging-related pathways.
Download or read book Bioactive Compounds from Medicinal Plants for Cancer Therapy and Chemoprevention written by Blassan George and published by Bentham Science Publishers. This book was released on 2024-09-10 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book aims to fill research gaps in the search for chemotherapeutic and chemopreventive natural compounds. It includes a collection of detailed reviews focusing on bioactive compounds from plant sources that can be beneficial for cancer therapy. Topics covered include the role of antioxidants in cancer therapy, medicinal plants for cancer chemotherapeutics, bioactive compounds from marine plants, and a review of inhibiting nitric oxide reactions for preventing cancer. Chapters are contributed by researchers who have provided detailed lists and descriptions of the relevant plant sources, the compounds and the biochemical reactions. The book includes references for advanced reading. This book is intended as a reference for scholars and healthcare professionals studying natural medicines for cancer prevention and treatment.
Download or read book Advanced and Modern Approaches for Drug Delivery written by Amit Kumar Nayak and published by Elsevier. This book was released on 2023-07-29 with total page 946 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advanced and Modern Approaches for Drug Delivery explores novel approaches currently used for drug delivery, including the must up-to-date techniques and technology. The approaches discussed allow pharmaceutical scientists to design effective drug delivery systems or devices for the management and treatment of numerous diseases and conditions. Detailed information on a wide variety of subjects, including dendrimers, lipid nanostructures, solid lipid nanoparticles, stimuli-responsive smart systems, self-assembled protein-drug nanoparticles, nanoconjugate formulations, nanofibers, iontophoretic systems, microneedle systems, ultra-sound triggered systems, targeted carrier-based intracellular delivery systems, resealed erythrocyte-based systems, 3 D-printing tool, site-specific monoclonal antibodies, and bio-inspired systems are all comprehensively discussed. With contributions from those in academia and industry, this book is an excellent reference for all those needing to understand drug delivery systems. - Provides thorough insights into the most up-to-date approaches and technologies for drug delivery and therapeutics - Discusses possible future approaches - Includes perspectives from industry and academia
Download or read book Hydrogels for Tissue Engineering and Regenerative Medicine written by J. Miguel Oliveira and published by Academic Press. This book was released on 2023-09-19 with total page 851 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hydrogels for Tissue Engineering and Regenerative Medicine: From Fundaments to Applications provides the reader with a comprehensive, concise and thoroughly up-to-date resource on the different types of hydrogels in tissue engineering and regenerative medicine. The book is divided into three main sections that describe biological activities and the structural and physicochemical properties of hydrogels, along with a wide range of applications, including their combination with emerging technologies. Written by a diverse range of international academics for professionals, researchers, undergraduate and graduate students, this groundbreaking publication fills a gap in literature needed in the tissue engineering and regenerative medicine field. - Reviews the fundamentals and recent advances of hydrogels in tissue engineering and regenerative medicine applications - Presents state-of-the-art methodologies for the synthesis and processing of different types of hydrogels - Includes contributions by leading experts in engineering, the life sciences, microbiology and clinical medicine
Download or read book Key Heterocyclic Cores for Smart Anticancer Drug Design Part II written by Rajesh Kumar Singh and published by Bentham Science Publishers. This book was released on 2022-09-02 with total page 231 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an update on heterocyclic compounds that serve as key components of anti-cancer agents administered in pre-clinical settings. Many of the compounds highlighted in the book are being actively investigated for the bioactive properties against a range of cancer cell lines. There is potential for heterocyclic compounds to design agents that can target specific molecules to treat different types of cancers. Chapters are contributed by experts in pharmaceutical chemistry and are written to give a general overview of the topic to readers involved in all levels of research and decision-making in pharmaceutical chemistry and anti-cancer drug design. Part 2 of the book set covers these topics: - Anticancer targets for heterocyclic lead compounds - Coumarin hybrids for cancer treatments - Progress in nitrogen and sulphur-based heterocyclic compounds for their anticancer activity - Imidazole as an anticancer heterocyclic ring - Morpholine for profiling anticancer lead compounds - Natural products as anticancer agents
