Download or read book Advances in Vasopressin and Oxytocin From Genes to Behaviour to Disease written by Rainer Landgraf and published by Elsevier. This book was released on 2008-09-10 with total page 657 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vasopressin and oxytocin are the key hormones of the hypothalamo-neurohypophysial system, and are well-known to be critically involved in antidiuresis, labor, and milk ejection. This book highlights the latest research on vasopressin and oxytocin, covering multiple biological aspects. The capacity of both hormones to regulate various aspects of social behaviours including pair-bonding, aggression, maternal love, and sexual behaviour, is a main focus, as are their interactions with a variety of other neuromodulators and transmitters. Moreover, the book illustrates the recent development of vasopressin and oxytocin agonists/antagonists as potential drugs to treat not only disturbances of body fluid homeostasis, but also mental disorders, including social phobia, autism, anxiety, and depression. The promising combination of basic and clinical research, comprising physiology, neuroendocrinology, behavioral biology, pharmacology, imaging and molecular genetics makes this book an essential addition to both experts and scientists new to the field alike. - Comprehensive review of OXT and AVP physiology and behaviour - Each chapter covers a novel aspect of OXT and AVP research and is written by a leading expert - Review articles are ideal for experts and newcomers to the field alike - Discusses fascinating behavioural effects of oxytocin and vasopressin - Summarizes the recent explosion of neuropeptide research, physiology and behaviour, is in one location
Download or read book Vasopressin and Oxytocin From Genes to Clinical Applications written by D. Poulain and published by Elsevier. This book was released on 2002-10-24 with total page 393 pages. Available in PDF, EPUB and Kindle. Book excerpt: The articles comprising this volume were first presented at the World Congress on Neurohypophysial Hormones held in Bordeaux, France on September 8-12, 2001. This conference brought together more than 170 scientists from 18 countries who belong to the different fields of interest representing research in the hypothalamo-neurohypophysial system. Two neurohypophysial neurohormones, oxytocin and vasopressin, exert a variety of central and peripheral actions and thus involve different scientific domains, which too often, even today, do not always find the appropriate occasion to interact. This volume is composed of chapters dealing with topics varying from basic and clinical neurosciences and neuroendocrinology, to reproductive, renal, cardiovascular physiology and pathology. It encompasses all areas of current neurohypophysial research and should be of vital interest as an integrative reference volume to specialized investigators and as an excellent introductory text to students, scientists and clinicians not yet closely familiar with the field. To ensure novelty and to make sure that all topics of current importance were covered, plenary and symposium speakers as well as poster presentations concentrated on recent advances made in the last few years.
Download or read book Vasopressin and Oxytocin written by Hans H. Zingg and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph provides a comprehensive overview of recent advances in the field of vasopressin and oxytocin. In the summer of 1997, scientists from over 20 countries congregated in Montreal for the 1997 World Congress of Neurohypophysial Hormones, a conference that united the fields of vasopressin, neurohypophysis and oxytocin in a single joint meeting that gave rise to the present book. The organization of a joint meeting was prompted by several recent developments. Specifically the molecular characterization of the vasopressin/oxytocin receptor family made it mandatory to adopt an integrated view and to discuss the vasopressin/oxytocin ligand/receptor family as a whole. To ensure em phasis on novelty, the conference focused on advances made over the last two years and also included important contributions by scientists that had not previously been associated with the vasopressin/oxytocin field. Vasopressin and oxytocin are two neurohormones that exert a wide spectrum of cen tral and peripheral actions. Accordingly, the vasopressin/oxytocin field embraces a large number of different domains, ranging from neuroscience, endocrinology, and oncology to renal, reproductive, and cardiovascular physiology and pathology.
Download or read book Oxytocin s routes in social behavior into the 21st century Precision Medicine approach for Oxytocin written by Alaine Keebaugh and published by Frontiers Media SA. This book was released on 2015-12-21 with total page 134 pages. Available in PDF, EPUB and Kindle. Book excerpt: Our brain is endowed with an incredible capacity to be social, to trust, to cooperate, to be altruistic, to feel empathy and love. Nevertheless, the biological underpinnings of such behaviors remain partially hardwired. Seminal research in rodents has provided important insights on the identification of specific genes in modulating social behaviors, in particular, the arginine vasopressin receptor and the oxytocin receptor genes. These genes are involved in regulating a wide range of social behaviors, mother-infant interactions, social recognition, aggression and socio-sexual behavior. Remarkably, we now know that these genes contribute to social behavior in a broad range of species from voles to humans. Indeed, advances in human non-invasive neuroimaging techniques and genetics have enabled scientists to begin to elucidate the neurobiological basis of the complexity of human social behaviors using "pharmacological fMRI" and "imaging genetics". Over the past few years, there has been a strong interest focused on the role of oxytocin in modulating human social behaviors with translational relevance for understanding neuropsychiatric disorders, such as autism, schizophrenia and depression, in which deficits in social perception and social recognition are key phenotypes. The convergence of this interdisciplinary research is beginning to reveal the complex nature of oxytocin’s actions. For instance, the way that oxytocin does influence social functioning is highly related to individual differences in social experiences, but also to the inter-individual variability in the receptor distribution of this molecule in the brain. Remarkably, despite the increasing evidence that oxytocin has a key role in regulating human social behavior, we still lack of knowledge on the core mechanisms of action of this molecule. Understanding its fundamental actions is a crucial need in order to target optimal therapeutic strategies for human social disorders. The originality of this Research Topic stands on its translational focus on bridging the gap between fundamental knowledge acquired from oxytocin research in voles and monkeys and recent clinical investigations in humans. For instance, what are the key animal findings that can import further knowledge on the mechanisms of actions of this molecule in humans? What are the key experiences that can be performed in the animal model in order to answer significant science gaps in the treatment of neuropsychiatric disorders? Hence, within this Research Topic, we will review the current state of the field, identify where the gaps in knowledge are, and propose directions for future research. This issue will begin with a comparative review that examines the role of this peptide in diverse animal models, which highlights the adaptive value of oxytocin’s function across multiple species. Then, a series of reviews will examine the role of oxytocin in voles, primates, and humans with an eye toward revealing commonalities in the underlying brain circuits mediating oxytocin’s effects on social behavior. Next, there will be a translational review highlighting the evidence for oxytocin’s role in clinical applications in psychopathology. Hence, via the continuum of basic to translational research areas, we will try to address the important gaps in our understanding of the neurobiological routes of social cognition and the mechanisms of action of the neuropeptides that guide our behaviors and decisions.
Download or read book Handbook of Neurochemistry and Molecular Neurobiology written by Ramon Lim and published by Springer Science & Business Media. This book was released on 2006-09-18 with total page 691 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The Handbook is intended to be a service to the neuroscience community, to help in finding available and useful information, to point out gaps in our knowledge, and to encourage continued studies. It represents the valuable contributions of the many authors of the chapters and the guidance of the editors and most important, it represents support for research in this discipline. Based on the rapid advances in the years since the second edition."--Publisher's website.
Download or read book Behavioral Pharmacology of Neuropeptides Oxytocin written by Rene Hurlemann and published by Springer. This book was released on 2018-07-09 with total page 586 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume collects cutting-edge expert reviews in the oxytocin field and will be of interest to a broad scientific audience ranging from social neuroscience to clinical psychiatry. The role of the neuropeptide oxytocin in social behaviors is one of the earliest and most significant discoveries in social neuroscience. Influential studies in animal models have delineated many of the neural circuits and genetic components that underlie these behaviors. These discoveries have inspired researchers to investigate the effects of oxytocin on brain and behavior in humans and its potential relevance as a treatment for psychiatric disorders including borderline personality disorder and autism and schizophrenia spectrum disorders. In fact, there is no established social psychopharmacology in Psychiatry, and oxytocin can be seen as the first endogenous agent specifically addressing social-cognitive impairment in psychiatric disorders, with animal research suggesting that it could be especially efficient in the early postnatal period. From a human perspective, it is crucial to understand more precisely who can benefit from potential oxytocin-related treatments, which outcome measures will best represent their effects, how they should be administered, and what brain mechanisms are likely involved in mediating their effects. This type of “precision medicine” approach is in line with the research domain criteria defined by the U.S. National Institute of Mental Health.
Download or read book Oxytocin s Routes in Social Behavior Into the 21st Century written by and published by . This book was released on 2015 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Our brain is endowed with an incredible capacity to be social, to trust, to cooperate, to be altruistic, to feel empathy and love. Nevertheless, the biological underpinnings of such behaviors remain partially hardwired. Seminal research in rodents has provided important insights on the identification of specific genes in modulating social behaviors, in particular, the arginine vasopressin receptor and the oxytocin receptor genes. These genes are involved in regulating a wide range of social behaviors, mother-infant interactions, social recognition, aggression and socio-sexual behavior. Remarkably, we now know that these genes contribute to social behavior in a broad range of species from voles to humans. Indeed, advances in human non-invasive neuroimaging techniques and genetics have enabled scientists to begin to elucidate the neurobiological basis of the complexity of human social behaviors using "pharmacological fMRI" and "imaging genetics". Over the past few years, there has been a strong interest focused on the role of oxytocin in modulating human social behaviors with translational relevance for understanding neuropsychiatric disorders, such as autism, schizophrenia and depression, in which deficits in social perception and social recognition are key phenotypes. The convergence of this interdisciplinary research is beginning to reveal the complex nature of oxytocin's actions. For instance, the way that oxytocin does influence social functioning is highly related to individual differences in social experiences, but also to the inter-individual variability in the receptor distribution of this molecule in the brain. Remarkably, despite the increasing evidence that oxytocin has a key role in regulating human social behavior, we still lack of knowledge on the core mechanisms of action of this molecule. Understanding its fundamental actions is a crucial need in order to target optimal therapeutic strategies for human social disorders. The originality of this Research Topic stands on its translational focus on bridging the gap between fundamental knowledge acquired from oxytocin research in voles and monkeys and recent clinical investigations in humans. For instance, what are the key animal findings that can import further knowledge on the mechanisms of actions of this molecule in humans? What are the key experiences that can be performed in the animal model in order to answer significant science gaps in the treatment of neuropsychiatric disorders? Hence, within this Research Topic, we will review the current state of the field, identify where the gaps in knowledge are, and propose directions for future research. This issue will begin with a comparative review that examines the role of this peptide in diverse animal models, which highlights the adaptive value of oxytocin's function across multiple species. Then, a series of reviews will examine the role of oxytocin in voles, primates, and humans with an eye toward revealing commonalities in the underlying brain circuits mediating oxytocin's effects on social behavior. Next, there will be a translational review highlighting the evidence for oxytocin's role in clinical applications in psychopathology. Hence, via the continuum of basic to translational research areas, we will try to address the important gaps in our understanding of the neurobiological routes of social cognition and the mechanisms of action of the neuropeptides that guide our behaviors and decisions.
Download or read book Neuropsychiatric Disorders written by Koho Miyoshi and published by Springer Science & Business Media. This book was released on 2010-08-09 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: Around the world societies are facing growing aging populations with the concomitant increase in neuropsychiatric disorders. Neuropsychiatric disorders are organic brain diseases with psychiatric symptoms, as in Alzheimer’s and Parkinson’s diseases, that cause cognitive impairment, including dementia, amnesic syndrome, and personality–behavioral changes. As a clinical science, neuropsychiatry aims to explore the complex interrelationship between behavior and brain function from a variety of perspectives, including those of psychology, neurology, and psychiatry. This concise and updated monograph comprises the latest findings in the field and includes chapters on delusional symptoms, mood disorders and neurotic symptoms, cognitive impairment, behavioral and personality changes, and recently, cerebral alterations revealed in PTSD patients and in endogenous psychoses through neuroimaging and neuropathology. These findings will certainly widen the realm of neuropsychiatry going forward and will prove of great value to specialists as well as to academics and trainees in neurology, psychiatry, neuropsychology, neuroradiology, neuropathology, neurophysiology, neurochemistry, and clinical genetics. Ultimately, neuropsychiatry aims to prevent and reduce the suffering of individuals with the psychiatric symptoms of cerebral disorders.
Download or read book Roles of Vasopressin and Oxytocin in Memory Processing written by Barbara McEwen and published by Academic Press. This book was released on 2004-09-15 with total page 791 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Roles of Vasopressin and Oxytocin in Memory Processing reviews research progress in a subfield of Behavioral Pharmacology concerned with vasopressin's (VP's) and oxytocin (OT's) roles in memory processing (MP). As hormones, VP is well-known for its pressor and antidiuretic action, and OT for its contribution to parturition and nursing. As neurotransmitters, they participate in a wide variety of self- and species-preserving functions expressed at psychological, physiological and behavioral levels. Advances in Pharmacology is available online on ScienceDirect — full-text online of volumes 48 onwards. Elsevier book series on ScienceDirect gives multiple users throughout an institution simultaneous online access to an important compliment to primary research. Digital delivery ensures users reliable, 24-hour access to the latest peer-reviewed content. The Elsevier book series are compiled and written by the most highly regarded authors in their fields and are selected from across the globe using Elsevier's extensive researcher network. For more information about the Elsevier Book Series on ScienceDirect Program, please visit:http://www.info.sciencedirect.com/bookseries/* Comprehensive coverage of both alternative theories and relevant research* Several key chapters reviewed by researchers whose studies and theories formed the subject matter of these chapters* Basic laboratory research focus with potential application for understanding and treating human memory disorders
Download or read book Oxytocin Vasopressin and Related Peptides in the Regulation of Behavior written by Elena Choleris and published by Cambridge University Press. This book was released on 2013-04-11 with total page 409 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comparative overview of the effects of neuropeptides on behavior, examining parallel findings in both humans and non-human animals.
Download or read book The Vasopressin System and Behavior written by Heather K. Caldwell and published by Frontiers Media SA. This book was released on 2018-11-16 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vasopressin and its homologues are evolutionarily ancient neuropeptides that are important to the neural modulation of behavior in many species. Over the last several decades there has been an emergence of cross-species consensus with regards to the broad behavioral domains that the vasopressin system influences. However, there are nuanced species- and sex-differences in the functions of this system, as well as evidence for cross-talk between this system and the oxytocin system. For this Research Topic, reviews and research articles from investigators across the field were solicited, with the goal to highlight some of the complexity and diversity within this system. This collection challenges researchers to broaden their understanding of this system as well as identifies areas in which additional research is needed. Topic areas featured include: - System complexity - Sex and species differences - Developmental effects - Human and non-human primates
Download or read book Advances in Vasopressin and Oxytocin From Genes to Behaviour to Disease written by Rainer Landgraf and published by Elsevier Science. This book was released on 2008-09-24 with total page 656 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vasopressin and oxytocin are the key hormones of the hypothalamo-neurohypophysial system, and are well-known to be critically involved in antidiuresis, labor, and milk ejection. This book highlights the latest research on vasopressin and oxytocin, covering multiple biological aspects. The capacity of both hormones to regulate various aspects of social behaviours including pair-bonding, aggression, maternal love, and sexual behaviour, is a main focus, as are their interactions with a variety of other neuromodulators and transmitters. Moreover, the book illustrates the recent development of vasopressin and oxytocin agonists/antagonists as potential drugs to treat not only disturbances of body fluid homeostasis, but also mental disorders, including social phobia, autism, anxiety, and depression. The promising combination of basic and clinical research, comprising physiology, neuroendocrinology, behavioral biology, pharmacology, imaging and molecular genetics makes this book an essential addition to both experts and scientists new to the field alike. . Comprehensive review of OXT and AVP physiology and behaviour . Each chapter covers a novel aspect of OXT and AVP research and is written by a leading expert . Review articles are ideal for experts and newcomers to the field alike . Discusses fascinating behavioural effects of oxytocin and vasopressin . Summarizes the recent explosion of neuropeptide research, physiology and behaviour, is in one location
Download or read book Advances in Health and Disease written by Lowell Duncan and published by . This book was released on 2021-08-17 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This edited volume includes seven chapters, each of which details a recent scientific advancement in health and disease. Chapter One describes polycystic ovary syndrome (PCOS) and elaborates various treatment, therapeutic, and management strategies for PCOS which may help in relieving its economic and social burden. Chapter Two addresses the ethical problems of the use of human fetal cell cultures in the manufacture of vaccines as well as other ethical dilemmas associated with vaccines. Chapter Three reviews fundamental aspects of imaging in the diagnosis of pneumomediastinum, including the normal mediastinal anatomy and relevant variants in plain radiography and computed tomography. Chapter Four summarizes current literature involving fasted exercise and health benefits and discusses the proposed mechanisms, aiming to determine fasted aerobic exercise applicability as a health-promoting strategy. Chapter Five examines the role that aerobic exercise plays in osteoporosis prevention and management, and how different exercise modalities contribute to bone health. Chapter Six reviews the main features of spontaneous pneumomediastinum, both in its asymptomatic and emergent forms, with focus on clinical signs and symptoms, natural course and the differential diagnosis. Lastly, Chapter Seven covers the current strategies for the management of gestational diabetes mellitus.
Download or read book The Oxford Handbook of Compassion Science written by Emma M. Seppälä and published by Oxford University Press. This book was released on 2017-09-26 with total page 557 pages. Available in PDF, EPUB and Kindle. Book excerpt: How do we define compassion? Is it an emotional state, a motivation, a dispositional trait, or a cultivated attitude? How does it compare to altruism and empathy? Chapters in this Handbook present critical scientific evidence about compassion in numerous conceptions. All of these approaches to thinking about compassion are valid and contribute importantly to understanding how we respond to others who are suffering. Covering multiple levels of our lives and self-concept, from the individual, to the group, to the organization and culture, The Oxford Handbook of Compassion Science gathers evidence and models of compassion that treat the subject of compassion science with careful scientific scrutiny and concern. It explores the motivators of compassion, the effect on physiology, the co-occurrence of wellbeing, and compassion training interventions. Sectioned by thematic approaches, it pulls together basic and clinical research ranging across neurobiological, developmental, evolutionary, social, clinical, and applied areas in psychology such as business and education. In this sense, it comprises one of the first multidisciplinary and systematic approaches to examining compassion from multiple perspectives and frames of reference. With contributions from well-established scholars as well as young rising stars in the field, this Handbook bridges a wide variety of diverse perspectives, research methodologies, and theory, and provides a foundation for this new and rapidly growing field. It should be of great value to the new generation of basic and applied researchers examining compassion, and serve as a catalyst for academic researchers and students to support and develop the modern world.
Download or read book Schizophrenia and Psychotic Spectrum Disorders written by S. Charles Schulz and published by Oxford University Press. This book was released on 2016-04-01 with total page 401 pages. Available in PDF, EPUB and Kindle. Book excerpt: Schizophrenia and Psychotic Spectrum Disorders aims to engage young caregivers in psychiatry, psychology, nursing and social work so that they will be able to become well informed about this significant--and at times confusing--illness. Because schizophrenia is considered to be one of the most complicated and severe psychiatric disorders, this book has the goal of summarizing key issues of the illness, such as its presentation, frequency and age of onset, and diagnostic characteristics. It also contains informative chapters about the pathophysiology of schizophrenia, ranging from brain development issues, genetics, and likely abnormalities in neurotransmitters. This book will give young professionals and those joining the field an excellent and accessible background to treatment. In this area, Schizophrenia and Psychotic Spectrum Disorders provides a comprehensive approach to diagnosis, treatment initiation, strategies for non-response, approaches of therapy, and importantly, ways to provide family therapy and support.
Download or read book Stress and Health written by William R. Lovallo and published by SAGE Publications. This book was released on 2015-01-29 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stress and Health: Biological and Psychological Interactions is a brief and accessible examination of psychological stress and its psychophysiological relationships with cognition, emotions, brain functions, and the peripheral mechanisms by which the body is regulated. Updated throughout, the Third Edition covers two new and significant areas of emerging research: how our early life experiences alter key stress responsive systems at the level of gene expression; and what large, normal, and small stress responses may mean for our overall health and well-being.
Download or read book Prosocial Development written by Laura M. Padilla-Walker and published by . This book was released on 2014 with total page 498 pages. Available in PDF, EPUB and Kindle. Book excerpt: Prosocial behavior-broadly defined as voluntary action intended to help or benefit another-has been associated with positive outcomes across the lifespan. Children with a more prosocial orientation are better liked and trusted by their peers, have a higher status in peer groups, are better at maintaining friendships, demonstrate better self regulation, empathy, and social cognitive skills, and excel in academics. Researchers have shown that prosocial behaviors correlate to lower rates of school suspension and drop-out, teen pregnancy, substance use, aggression, and delinquency. These positive effects speak to the value of prosocial behavior during formative years. Prosocial Development examines a variety of biological, socialization, and contextual influences on prosocial development from infancy through early adulthood. While the definition of prosocial behavior may seem straightforward, recent research has highlighted its multifaceted nature. This volume specifically focuses on the multidimensionality of prosocial development, examining different contexts, motivations, types, and targets of prosocial behavior that are differentially predicted by socialization and dispositional characteristics. Skillfully edited by Drs. Padilla-Walker and Carlo, each chapter in this volume highlights some aspect of multidimensionality in regard to prosocial behavior and meaningful avenues for future research. This volume will be an important tool for scholars, researchers, and practitioners who are interested in prosocial, moral, and positive youth development. The organization and focus of this volume are also well-suited for use as a text for graduate courses in moral development, child and adolescent development, social psychology, sociology, anthropology, and family studies.
