Download or read book Advances in Rapid Sex Steroid Action written by Gabriella Castoria and published by Springer Science & Business Media. This book was released on 2011-12-15 with total page 271 pages. Available in PDF, EPUB and Kindle. Book excerpt: Breast and prostate cancers are both hormone-dependent, at least in some stages of their progression. Hormonal manipulation represents an important therapeutic approach. Although most of breast and prostate cancers initially respond to hormone therapy, most tumors reinitiate to growth. Finally, hormone-resistant and metastatic breast and prostate cancers may develop. Thus, the challenge is the dissection of mechanisms by which steroid receptor signaling pathways continue to influence cell growth and invasiveness. Compelling evidence indicates that steroid hormones elicit non-genomic responses in extra-nuclear compartment of target cells. In this cellular location, steroid-coupled receptors rapidly recruit signaling effectors or scaffold proteins and activate multiple pathways leading to proliferation, survival, migration and invasiveness. The immediate challenge is the dissection of key events regulating the steroid response of target tissues to prevent progression and improve treatment of breast and prostate cancers.
Download or read book Advances in Rapid Sex Steroid Action written by Gabriella Castoria and published by Springer. This book was released on 2011-12-14 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: Breast and prostate cancers are both hormone-dependent, at least in some stages of their progression. Hormonal manipulation represents an important therapeutic approach. Although most of breast and prostate cancers initially respond to hormone therapy, most tumors reinitiate to growth. Finally, hormone-resistant and metastatic breast and prostate cancers may develop. Thus, the challenge is the dissection of mechanisms by which steroid receptor signaling pathways continue to influence cell growth and invasiveness. Compelling evidence indicates that steroid hormones elicit non-genomic responses in extra-nuclear compartment of target cells. In this cellular location, steroid-coupled receptors rapidly recruit signaling effectors or scaffold proteins and activate multiple pathways leading to proliferation, survival, migration and invasiveness. The immediate challenge is the dissection of key events regulating the steroid response of target tissues to prevent progression and improve treatment of breast and prostate cancers.
Download or read book Recent Advances in Steroid Hormone Action written by V. K. Moudgil and published by Walter de Gruyter GmbH & Co KG. This book was released on 2019-07-22 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: No detailed description available for "Recent Advances in Steroid Hormone Action".
Download or read book Neurobiological Effects of Sex Steroid Hormones written by Paul E. Micevych and published by Cambridge University Press. This book was released on 1995-05-26 with total page 468 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurobiological Effects of Sex Steroid Hormones describes the neurobiological basis for the understanding of how sex steroid hormones, oestrogen and testosterone, interact with parts of the brain. The contributors have all made significant advances in the understanding of how these steroids regulate neural function, and how this activity is translated into reproductive behaviours necessary for the propagation of the species. This book covers a broad range of topics, extending from the molecular and cellular processes, through the action of steroids on neurotransmission, all the way to defining the brain circuitry involved in both male and female behaviour. This volume presents a snapshot of the rapidly advancing field of reproductive neuroendocrinology by the investigators who are most intimately involved with the discoveries.
Download or read book Sex Hormones in Neurodegenerative Processes and Diseases written by Gorazd Drevensek and published by BoD – Books on Demand. This book was released on 2018-05-02 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book provides chapters on sex hormones and their modulation in neurodegenerative processes and pathologies, from basic molecular mechanisms, physiology, gender differences, to neuroprotection and clinical aspects for potential novel pharmacotherapy approaches. The book contains 14 chapters written by authors from various biomedical professions, from basic researchers in biology and physiology to medicine and veterinary medicine, pharmacologists, psychiatrist, etc. Chapters sum up the past and current knowledge on sex hormones, representing original new insights into their role in brain functioning, mental disorders and neurodegenerative diseases. The book is written for a broad range of audience, from biomedical students to highly profiled medical specialists and biomedical researchers, helping them to expand their knowledge on sex hormones in neurodegenerative processes and opening new questions for further investigation.
Download or read book Advanced Exercise Endocrinology written by Katarina T. Borer and published by Human Kinetics. This book was released on 2013 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advanced Exercise Endocrinology provides a comprehensive examination of the relationship between physical activity and hormone function. It is an essential reference for exercise physiologists and physiotherapists researching the connections between exercise, hormone function, and health.
Download or read book Sex Steroids written by Scott M. Kahn and published by BoD – Books on Demand. This book was released on 2012-01-27 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, entitled "Sex Steroids", features a valuable collection of reviews and research articles written by experts in signal transduction, cellular biology, diseases and disorders. "Sex Steroids" is comprised of four sections, "The Biology of Sex Steroids", "Sex Steroids, Memory, and the Brain", "Sex Steroids and the Immune Response", and "Therapy"; individual chapters address a broad range of recognized and predicted functions and applications of sex steroids. "Sex Steroids" is intended to provide seasoned veterans as well as newcomers to this area of research with informative, resourceful, and provocative insights. Readers of "Sex Steroids" should emerge with an appreciation and understanding of the multitude and complexity of biologic processes attributed to these important hormones, and possible future directions of research in this fascinating and ever evolving field.
Download or read book Diagnosis and Management of Ovarian Disorders written by Albert Altchek and published by Elsevier. This book was released on 2003-09-04 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt: This updated second edition of Diagnosis and Management of Ovarian Disorders provides thorough, yet succinct insight into the ever-changing realm of ovarian disorders. It presents a novel multidisciplinary approach to the subject as described by clinicians, surgeons, pathologists, basic scientists and related medical researchers. Topics covered include reproductive technology, early diagnosis of ovarian cancer, and management of menopause among others. The breadth of information provided by this book will appeal to clinicians and researchers involved in the study and treatment of ovarian disorders. KEY FEATURES * Includes updated information on early diagnosis of ovarian cancer * Reviews new diagnostic techniques for ovarian disorders * Discusses latest information on reproductive technology * Presents translational treatment linking laboratory research with clinical medicine
Download or read book Progress in the Management of the Menopause Proceedings of the 8th International Congress on the Menopause Sydney Australia written by B.G. Wren and published by CRC Press. This book was released on 2020-07-26 with total page 508 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a comprehensive, up-to-date, authoritative research text and clinical reference work the menopause. It contains over 90 contributions covering every conceivable topic in the management of the menopause in women and related issues in the aging male. The book contains many illustrations and a wealth of references.
Download or read book Progress in Molecular Biology and Translational Science written by and published by Academic Press. This book was released on 2018-11-20 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: Progress in Molecular Biology and Translational Science, Volume 160 provides the most topical, informative and exciting monographs available on a wide variety of research topics related to prions, viruses, bacteria and eukaryotes. The series gives in-depth knowledge on the important molecular biological aspects of organismal physiology and function, along with insights on how this knowledge can be applied to understand and ameliorate human disease. This updated release covers Clinical Drugs in the Environment, Group I Intron Trans-Splicing, Adult Stem Cells on Regenerative Therapy, CRISPR in Animals and Animal Models, The Role of 3’–5’Exoribonucleases in RNA Degradation, and more. Comprises 15-20 chapters, which allows substantial coverage on a given topic Contains ample use of tables, diagrams, schemata, and color figures to enhance the reader's ability to rapidly grasp the information provided in each chapter Provides a comprehensive guide to the latest information available on prions, viruses, bacteria, and eukaryotes
Download or read book Steroid Hormone Resistance written by George P. Chrousos and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume represents the first attempt to present in one place the clinical syndromes and the pathophysiologic basis for the "resistance states" to each of the classes of steroid hormones. Glucocorticoids, mineralocorticoids, androgens, estrogens, progesterone and vitamin D have widely diverse roles ranging from the control of homeostasis to reproduction and bone formation. They are similar in that they share a chemical structure and that their action is in the cell nucleus where they induce transcription of specific genes leading to synthesis of function-specific proteins. Clinical syndromes of steroid hormone resistance to androgens (complete and partial testicular feminization), aldosterone (pseudo hypoaldosteronism) and vitamin D (vitamin D-dependent rickets type II) have been known for many years. Progesterone and glucocorticoid resistance syndromes have been described only recently. Resistance to estrogens has not been reported in man or in animals. It is hoped that a detailed reexamination of what is known about each of these conditions at the clinical and molecular levels will enhance our understanding of the function of these hormones and their mechanisms of action. New insight and research initiatives should result. G.P. Chrousos D.L. Loriaus M.B. Lipsett vii ACKNOWLEDGMENTS The contents of this volume are based in part on the proceedings of an International Conference held in Bethesda in the summer of 1984. This conference was sponsored by the National Institute of Child Health and Human Development, Bethesda, Maryland.
Download or read book Progress Report written by Center for Population Research (National Institute of Child Health and Human Development (U.S.)). and published by . This book was released on 1984 with total page 92 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Progress Report written by Center for Population Research (National Institute of Child Health and Human Development) and published by . This book was released on 1984 with total page 92 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Modern Medicines from Plants written by Henry Oakeley and published by CRC Press. This book was released on 2023-08-24 with total page 567 pages. Available in PDF, EPUB and Kindle. Book excerpt: The full colour, beautifully illustrated Modern Medicines from Plants: Botanical histories of some of modern medicine’s most important drugs features information on plants from which we obtain modern prescription medicines. It outlines their historical uses as herbal medicines in the past two millennia, using primary sources, and describes how extracts from them, and their semisynthetic and synthetic derivatives, were developed to be today’s therapeutic drugs and diagnostic chemicals. This book describes medicinal plants and their habitats, the diseases that their medicines treat, and the science of how they work. This amazing and unique book is a wonderful read for those with an interest in both herbal and prescription medicines. Written with authority by physicians and gardeners at the Garden of Medicinal Plants at the Royal College of Physicians, London, chapters detail the history and modern scientific research on plants and their medicines. It is very useful to physicians, pharmacists, herbalists, historians and gardeners, bringing together information from every discipline to make it a work of interest as well as reference. Features · Written for people interested in medicinal plants, where medicines come from, and how they treat our diseases. · Contains information on 50 plants, mostly growing in the medicinal garden of the Royal College of Physicians in London, describing how they became the source of modern pharmaceutical medicines. · Describes medicinal uses of plants in Classical Greece as written by Dioscorides, Pliny and Galen, through the flowering of Arabic medicine by physicians such as Paulus Aegineta, Mesue and Avicenna to the 12th to 14th century compilations of Serapion and Sylvaticus and the European Renaissance of Peter Treveris, William Turner, Leonard Fuchs, Pietro Mattioli, John Gerarde, John Parkinson, Nicholas Culpeper, and many others to the pharmacopoeias of the 16th century to the present day. · Fully referenced including a glossary for explanation of technical terms.
Download or read book Sex Differences in Physiology written by Gretchen Neigh and published by Academic Press. This book was released on 2016-05-10 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sex Differences in Physiology is an all-encompassing reference that details basic science research into sex differences in all physiological fields. It includes scientific discoveries concerning sex differences in cardiovascular, respiratory, renal, gastrointestinal, and musculoskeletal physiology. In addition, coverage of the development, endocrinology, neurophysiology, immunity, and metabolism is included, making this important reference a resource that will meet the needs of investigators interested in incorporating sex differences into their research programs, while also providing clinicians with the basis for providing the best sex-based medical treatment options available. Provides a sweeping, organ-by-organ review of currently observed sex differences in animal models and human disease Explains how sex differences influence physiology and disease Provides the critical knowledge on sex differences for better understanding of prevention and treatment of diseases
Download or read book Progress Report of the Center for Population Research National Institute of Child Health and Human Development written by Center for Population Research (National Institute of Child Health and Human Development) and published by . This book was released on 19?? with total page 88 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Progress Report of the Center for Population Research National Institute of Child Health and Human Development written by Center for Population Research (National Institute of Child Health and Human Development (U.S.)) and published by . This book was released on with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt:
