Download or read book Advances in diagnosing and treating new onset refractory status epilepticus NORSE written by Aljoscha Thomschewski and published by Frontiers Media SA. This book was released on 2023-10-05 with total page 150 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book NORSE and Super Refractory Status Epilepticus written by and published by . This book was released on 2019 with total page 20 pages. Available in PDF, EPUB and Kindle. Book excerpt: New-Onset Refractory Status Epilepticus (NORSE) is a rare life-threatening condition in previously healthy patients who develop new-onset medically-refractory status epilepticus of unclear etiology. NORSE commonly leads to super-refractory status epilepticus (SRSE), a severe form of status epilepticus for which seizures persist despite 24 hours of adequate anti-seizure and anesthetic treatment. The goal of this study is to examine the clinical characteristics and epidemiology of super-refractory NORSE, a subset of SRSE, to determine risk and prognostic factors associated with this rare condition, and mortality rates. We performed a retrospective cohort study of all cases of SRSE admitted to Oregon Health & Science University between 2007 and 2016. Among 358 patients monitored on continuous EEG for at least 4 days in a single admission, 67 were identified as having SRSE. In-hospital mortality for SRSE (all causes) was 30%, but for the specific NORSE group 15%, for pre-existing epilepsy 40% and for symptomatic 32%. The results of this study are consistent with prior reports of NORSE epidemiology: the condition is rare, patients tend to be younger, female-predominate, and there have been no antibodies clearly-associated with the condition. A novel finding in this study was that 50% of NORSE cases had positive antibody testing- the majority of which were thyroid-associated antibodies. Based on a population-based study at baseline of 5783 participants, 12.8% were positive for TPO antibodies with a higher prevalence in women compared to men. While thyroid-associated antibodies are thought to be non-specific markers of inflammation and/or autoimmunity, this supports the hypothesis that NORSE (or a subset of NORSE cases) may be autoimmune-mediated and establishes a potential autoimmune link.
Download or read book Atlas of EEG in Critical Care written by Lawrence J. Hirsch and published by John Wiley & Sons. This book was released on 2011-08-17 with total page 639 pages. Available in PDF, EPUB and Kindle. Book excerpt: As the population ages, technology improves, intensive care medicine expands and neurocritical care advances, the use of EEG monitoring in the critically ill is becoming increasingly important. This atlas is a comprehensive yet accessible introduction to the uses of EEG monitoring in the critical care setting. It includes basic EEG patterns seen in encephalopathy, both specific and non-specific, nonconvulsive seizures, periodic EEG patterns, and controversial patterns on the ictal–interictal continuum. Confusing artefacts, including ones that mimic seizures, are shown and explained, and the new standardized nomenclature for these patterns is included. The Atlas of EEG in Critical Care explains the principles of technique and interpretation of recordings and discusses the techniques of data management, and 'trending' central to long-term monitoring. It demonstrates applications in multi-modal monitoring, correlating with new techniques such as microdialysis, and features superb illustrations of commonly observed neurologic events, including seizures, hemorrhagic stroke and ischaemia. This atlas is written for practitioners, fellows and residents in critical care medicine, neurology, epilepsy and clinical neurophysiology, and is essential reading for anyone getting involved in EEG monitoring in the intensive care unit.
Download or read book Refractory Status Epilepticus written by Xuefeng Wang and published by Springer. This book was released on 2017-09-05 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book aims to offer the accumulated fertile experience of treating drug-resistant epileptic patients collected over the past few decades, focusing on aspects of neurology, neurosurgery, emergency care, critical care medicine and basic medical research. Refractory status epilepticus is one of the most common severe and acute diseases in neurology and neurocritical care; it is also the main cause of death in epileptic patients. In the context of prevention and treatment processes, it is not only necessary to terminate epileptic seizures, but to also address the disruption of the patient’s internal environment and provide critical life support. Effective treatment calls for multi-disciplinary support from neurology, neurosurgery, emergency care, critical care medicine, and other fields. Further, since the clinical features of epileptic seizure are not specific, it is necessary to differentiate it from other diseases that produce convulsions, disorders of consciousness, syncope, mental and behavioral disorders, myoclonus, etc., to avoid misdiagnosis. In this book, it comprehensively and systematically describes the basic knowledge as well as prevention and treatment tips, providing an invaluable reference resource for medical students and professionals in neurology, neurosurgery, emergency care and critical care medicine.
Download or read book Epilepsy written by Jerome Engel and published by Lippincott Williams & Wilkins. This book was released on 2008 with total page 1272 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written and edited by world-renowned authorities, this three-volume work is, to quote a reviewer, "the definitive textbook about seizures and epilepsy". This Second Edition is thoroughly updated and gives you a complete print and multimedia package: the three-volume set plus access to an integrated content Website. More than 300 chapters cover the spectrum of biology, physiology, and clinical information, from molecular biology to public health concerns in developing countries. Included are detailed discussions of seizure types and epilepsy syndromes; relationships between physiology and clinical events; psychiatric and medical comorbidity; conditions that could be mistaken for epilepsy; and an increasing range of pharmacologic, surgical, and alternative therapies, including vagus nerve stimulation and deep brain stimulation. This edition describes many new antiepileptic drugs, major advances in surgical treatment, and state-of-the-art neuroimaging, EEG, and other technologies for diagnosis and seizure prediction. A companion Website offers instant access to the complete, fully searchable text, plus an image bank of additional figures, video footage, and annual updates to selected chapters.
Download or read book Nonconvulsive Status Epilepticus written by Frank W. Drislane, MD and published by Demos Medical Publishing. This book was released on 2008-11-05 with total page 317 pages. Available in PDF, EPUB and Kindle. Book excerpt: The only comprehensive source of information on this frequently misdiagnosed problem, with information critical for physicians, ER and ICU doctors, and psychiatrists. An under-recognized condition that can potentially cause brain damage and even death, nonconvulsive status epilepticus (NCSE) is an important clinical problem, occurring in about 25% of status epilepsy cases. Despite this prevalence, Nonconvulsive Status Epilepticus is the first comprehensive clinical text to cover its diagnosis and management. The book progresses logically, beginning with chapters discussing the history and classification of NCSE, reflecting a contemporary understanding of developmental, syndromic, and clinical aspects. Following chapters discuss relevant epidemiology, electrophysiology, imaging and pathophysiology of NCSE, with supplementary sections devoted to psychiatric and behavioral aspects of NCSE and to the different diagnostic considerations of its frequently unusual behavioral presentations. Highlights include: An emphasis on diagnosis, management, and all pertinent clinical issues A heavily illustrated section on EEG interpretation in NCSE Contributions by the foremost international experts on NCSE Throughout, the book maintains a practical focus on recognizing the key signs and symptoms of this subtly presented and clinically challenging condition. This multidisciplinary volume will provide physicians, ER and ICU doctors, and psychiatrists with a comprehensive source of information and opinion on nonconvulsive status epilepticus.
Download or read book Status Epilepticus written by Frank W. Drislane and published by Springer Science & Business Media. This book was released on 2007-10-28 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: A panel of senior clinicians critically reviews the many forms of status epilepticus (SE), their causes, manifestations, methods of diagnosis, and appropriate treatments. The emphasis is on the disease as encountered by the clinician in the field and the importance of correct recognition and diagnosis. The authors provide for each form of SE the underlying genetic, biological, and developmental background, the pathophysiological processes, as well as the precipitating factors that lead to an episode. For the difficult problem of diagnosing nonconvulsive SE, they offer detailed syndrome classifications, differential diagnoses, descriptions of seizure "imitators," notes on unusual behavioral and cognitive manifestations, and carefully delineated clinical presentations. Additional highlights include striking EEG reproductions that provide classic examples of patients in SE, SE in very young children and neonates, and an analysis of the cellular physiology and processes occurring during SE.
Download or read book Neurointensive Care Unit written by Sarah E. Nelson and published by Springer Nature. This book was released on 2020-03-18 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers valuable guidance to neurointensivists, other neurocritical care staff, and those desiring to develop a neurocritical care unit via a thorough discussion of neurological emergencies and neurocritical care unit organization. This comprehensive volume begins with a review of acute neurological emergencies as managed clinically in the neurocritical care unit. Topics include acute cerebrovascular, neurological, and neurosurgical disorders. The unique aspect of this book is its description of the organization of the neurocritical care unit. We focus on how other services in the hospital interact with and assist neurocritical care operations, telemedicine/telestroke, and neurocritical care personnel and their roles. A review of expected outcomes of neurocritical care conditions is also included. Neurointensivists, neurocritical care unit staff leadership, hospital administrators, and those interested in developing a neurocritical care unit will find Neurointensive Care Unit: Clinical Practice and Organization to be an invaluable guide.
Download or read book Neurological Emergencies written by S.D. Shorvon and published by Butterworth-Heinemann. This book was released on 2013-10-22 with total page 121 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurological Emergencies presents a comprehensive guide on the initial assessment and early treatment of patients with neurological emergencies. It discusses the diagnosis, emergency investigations, and handling of coma patients. It addresses the management of focal supratentorial lesion. Some of the topics covered in the book are the diffuse neurological or systemic disturbance; emergency resuscitation; diagnosis and treatment of transtentorial herniation; diagnosis and treatment of acute viral encephalitis; raised intracranial pressure; diagnosis and treatment of non-viral infective encephalitis; viral meningitis; meningovascular syphilis; diagnosis and treatment of cerebral abscess; diagnosis and treatment of intracranial subdural empyema; and diagnosis and treatment of cerebral venous thrombosis. The diagnosis and treatment ofstroke is fully covered. An in-depth account of the difference between haemorrhage and infarction is provided. The diagnosis of subarachnoid haemorrhage is completely presented. A chapter is devoted to the prevention of more cranial bleeding.
Download or read book Continuous EEG Monitoring written by Aatif M. Husain and published by Springer. This book was released on 2017-01-04 with total page 660 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is designed to meet the need for a practically oriented textbook on the rapidly growing field of continuous EEG (cEEG) monitoring. A wide range of key clinical aspects are addressed, with explanation of status epilepticus classification, criteria for institution of monitoring, seizure patterns and their recognition, quantitative EEG analysis, and neuroimaging in patients undergoing cEEG monitoring. The value of cEEG and the nature of cEEG findings in various special situations are then reviewed, covering particular pathologies, critical care considerations, and prognostication. Treatments of nonconvulsive status epilepticus (NCSE) and nonconvulsive seizures (NCS) are discussed. The concluding section is devoted to important administrative issues including billing, staffing issues, comparison of EEG machines, and information technology (IT) issues.Continuous EEG monitoring offers the only reliable means of detecting seizures that are not clinically obvious in critically ill patients. Such seizures are common: approximately 20% of patients undergoing cEEG monitoring in hospital have NCSE or NCS. Against this background, many hospitals have started to offer cEEG monitoring as a basis for delivery of appropriate treatment. By presenting the state of the art in cEEG monitoring, this book will be invaluable to practitioners including neurophysiologists, neurologists, neurointensivists, intensivists, neurophysiology and epilepsy fellows, and neurology residents.
Download or read book The Causes of Epilepsy written by Simon Shorvon and published by Cambridge University Press. This book was released on 2019-05-02 with total page 1013 pages. Available in PDF, EPUB and Kindle. Book excerpt: Expanded and revised, this unique book provides concise descriptions of the many causes of epilepsy, for use in clinical practice.
Download or read book Surgical Intensive Care Medicine written by John M. O'Donnell and published by Springer Science & Business Media. This book was released on 2009-11-18 with total page 711 pages. Available in PDF, EPUB and Kindle. Book excerpt: We are honored to present the second edition of Surgical Intensive Care Medicine. Our first edition was considered to be an important contribution to the critical care literature and received excellent reviews from Critical Care Medicine, Chest, and Anesthesiology. In the second edition, the basic organization of the book remains unchanged, being composed of 60 carefully selected chapters divided into 11 sections. The book begins with general topics in primary intensive care, such as airway management and vascular cannulation, followed by categories based on medical and surgical subspecialties. While the chapters discuss definitions, pathophysiology, clinical course, complications, and prognosis, the primary emphasis is devoted to patient management. The contents of the current edition have been comprehensively upgraded and the chapters retained from the first edition have been thoroughly updated, revised, or rewritten. In this second edition, some new topics have been added including Postoperative Care of the Obese Patient, Postoperative Care of the Pancreas Transplant Patient, Optimization of High-Risk Surgical Patients, Post- erative Alcohol Withdrawal Syndrome, Ethics and End of Life Issues, Improving the ICU, and Continuous Medical Education in Intensive Care Medicine. We are extremely fortunate to have high-quality contributors, many of whom are nationally and internationally recognized researchers, speakers, and practitioners in Cri- cal Care Medicine. An important feature of this latest edition is the geographical diversity of its authors. Most are based in the United States, but colleagues from Canada, England, Ireland, Germany, Belgium, Holland, France, Italy, Portugal, and Australia have also made notable contributions.
Download or read book Bullets and Brains written by Andrew Nathan Wilner, M.d. and published by . This book was released on 2013-10 with total page 532 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bullets and Brains is a collection of over 100 essays about people and their brains written by a neurologist and epilepsy specialist. These articles appeared over the last four years in two Medscape.com columns, “Wilner on Neurology” and “Epilepsy Notes,” as well as other special articles. Medscape.com is a division of WebMD, a leading provider of health information.Although written for a medical audience, most of these essays focus on the intersection of neurology and society and are easily accessible to the inquisitive reader. As one reader wrote, “I felt as if I was in a comfortable conversation over a good coffee with the author.”
Download or read book Continuous Spikes and Waves During Slow Sleep written by Fondazione Pierfranco e Luisa Mariani and published by John Libbey Eurotext. This book was released on 1995 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book collects the results of clinical experience and research, as well as the opionions of the specialists who have studied in depth several rare and complex syndromes associated with "Continuous Spikes and Waves During Slow Sleep", the Landau-Kleffner syndrome, and related conditions. It also presents a wide-ranging collection of cases presented by the participants in the meeting, and analysed in its various clinical, electrophysiological and psycho-intellectual aspects. The purpose of the book is to provide a thorough updated on specialised knowledge about the syndromes characterised by the presence of CSWS on the EEG, to bring out the many, still unanswered -- questions, and to stimulate further interdisciplinary research to verify the validity of present hypotheses, in order to clarify which preventive and therapeutic methods can best attain the control of such syndromes.
Download or read book Neurological Emergencies written by Alejandro A. Rabinstein and published by Springer Nature. This book was released on 2019-11-28 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive and up-to-date book covers the common emergencies in neurology, neurosurgery, and psychiatry. Chapters examine a variety of neurological emergencies, and offer pragmatic approaches to treatment and management. High-quality tables, figures, and algorithms supplement expertly written text, and provide readers with clear, rapid answers in an easily accessible format. Additionally, the book includes discussions on less common conditions, and incorporates specific methods for treating specific populations, such as pregnant women and transplant patients. Neurological Emergencies: A Practical Approach is a go-to reference for all medical professions working in emergency treatment settings, and will increase their ability to better care for patients with acute neurological diseases.
Download or read book Clinical Neuroradiology written by Frederik Barkhof and published by Springer. This book was released on 2019-04-16 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This superbly illustrated textbook, endorsed by the European Society of Neuroradiology, explains in detail the clinical importance of neuroradiology in complementing history taking and physical examination during the workup of patients suspected of having neurological, neurosurgical, or psychiatric disorders. The role of imaging of the brain and spinal cord is described across the full range of relevant conditions, including, for example, cerebrovascular diseases, trauma, CSF disorders, developmental malformations, autoimmune diseases, epilepsy, tumors and tumor-like conditions, neurodegenerative diseases, metabolic conditions, and bipolar and depressive disorders. The structured approach to imaging and image analysis will ensure that the book is an invaluable resource for neuroradiologists in training and clinicians alike. Starting from the clinical indication, suggestions for imaging protocols are provided and checklists of common findings and aspects key to interpretation are presented. The book is published within the SpringerReference program, which combines thorough coverage with access to living editions constantly updated via a dynamic peer-review process.
Download or read book Seizures in Critical Care written by Panayiotis Varelas and published by Springer Science & Business Media. This book was released on 2008-08-17 with total page 391 pages. Available in PDF, EPUB and Kindle. Book excerpt: A panel of international ICU and epilepsy physicians and researchers detail the epileptic phenomena that occur in the complex environment of the ICU. Focusing on the central nervous system, the authors systematically examine the most up-to-date evidenced-based data regarding ICU seizures, including their most frequent causes, their pathophysiology, their clinical presentation, and the diagnostic evaluation needed to confirm their presence. They also discuss the challenges and specifics of the management of ICU seizures, reviewing the new antiepileptics and their interaction with other ICU medications, drugs with epileptogenic properties used in the ICU, and the role of the new enterally available antiepileptics in treating seizures. Numerous tables summarize drug interactions, neuroimages reveal common ICU seizure etiologies, and multiple electroencephalographic recordings demonstrate clinical or subclinical seizures in ICU patients.
