Download or read book Advances in Combination Therapy for Asthma and COPD written by Jan Lotvall and published by John Wiley & Sons. This book was released on 2011-11-28 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aimed at specialists in respiratory medicine, this new book comprehensively reviews the variety of agents currently available for treatment of asthma, COPD, and other airway diseases and covers practical guidelines as well as challenges and complications in their use. Advances in Combination Therapy for Asthma and COPD is the first book to address the complexity of multi-agent therapy and deal with management issues in an integrated fashion. A review of currently available agents and their applications, as well as new therapies soon to become available are outlined. Advantages of combined therapies and additional considerations that arise from multi-agent programs are highlighted.

Download or read book Combination Therapy for Asthma and Chronic Obstructive Pulmonary Disease written by Richard Martin and published by CRC Press. This book was released on 2000-04-18 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book examines the therapies used for treatment of asthma and chronic obstructive pulmonary disease (COPD) separately and in combination, covering beta-agonists, theophylline, leukotriene modifiers, and anticholinergics. Highlights the importance of specific time dosing of medications! Revealing what medications to use and when to prescribe them, Combination Therapy for Asthma and Chronic Obstructive Pulmonary Disease emphasizes anti-inflammatory therapy compares and contrasts the side effects and efficacy of titration and various combinations covers the steroid-sparing effect of combining inhaled corticosteroids and long-acting beta 2-agonists includes over 1100 references that clarify outcomes among several different agents details the mechanisms of inhaled glucocorticoid action and more! Written by clinicians who are experts in the pharmacological agents discussed, Combination Therapy for Asthma and Chronic Obstructive Pulmonary Disease is critical for pulmonologists, clinical immunologists/allergists, pharmacologists, internists, family practice physicians, pediatricians, and hospital interns and residents.

Download or read book Targeting Chronic Inflammatory Lung Diseases Using Advanced Drug Delivery Systems written by Kamal Dua and published by Academic Press. This book was released on 2020-08-04 with total page 620 pages. Available in PDF, EPUB and Kindle. Book excerpt: Targeting Chronic Inflammatory Lung Diseases Using Advanced Drug Delivery Systems explores the development of novel therapeutics and diagnostics to improve pulmonary disease management, looking down to the nanoscale level for an efficient system of targeting and managing respiratory disease. The book examines numerous nanoparticle-based drug systems such as nanocrystals, dendrimers, polymeric micelles, protein-based, carbon nanotube, and liposomes that can offer advantages over traditional drug delivery systems. Starting with a brief introduction on different types of nanoparticles in respiratory disease conditions, the book then focuses on current trends in disease pathology that use different in vitro and in vivo models. The comprehensive resource is designed for those new to the field and to specialized scientists and researchers involved in pulmonary research and drug development. Explores recent perspectives and challenges regarding the management and diagnosis of chronic respiratory diseases Provides insights into how advanced drug delivery systems can be effectively formulated and delivered for the management of various pulmonary diseases Includes the most recent information on diagnostic methods and treatment strategies using controlled drug delivery systems (including nanotechnology)

Download or read book Asthma and COPD written by Peter J. Barnes and published by Elsevier. This book was released on 2009-03-19 with total page 897 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Second Edition of Asthma and COPD: Basic Mechanisms and Clinical Management continues to provide a unique and authoritative comparison of asthma and COPD. Written and edited by the world's leading experts, it continues to be a comprehensive review of the most recent understanding of the basic mechanisms of both conditions, specifically comparing their etiology, pathogenesis, and treatments. * Each chapter considers Asthma and COPD in side-by-side contrast and comparison – not in isolation - in the context of mechanism, triggers, assessments, therapies, and clinical management * Presents the latest and most comprehensive understandings of the mechanisms of inflammation in both Asthma and COPD * Most extensive reference to primary literature on both Asthma and COPD in one source. * Easy-to-read summaries of the latest advances alongside clear illustrations

Download or read book Controversies in COPD written by Antonio Anzueto and published by European Respiratory Society. This book was released on 2015-09-01 with total page 341 pages. Available in PDF, EPUB and Kindle. Book excerpt: COPD is one of the most common diseases worldwide and is projected to be the third leading cause of death by 2020. But that does not mean it is easy to understand or manage. In everyday practice, pulmonologists face areas of controversy in COPD, for which evidence-based medicine is often unavailable. This ERS Monograph considers where the current controversies in COPD lie, discussing areas such as screening, premature birth, asthma–COPD overlap syndrome, treatment, rehabilitation and palliative care. This book will be of great interest to both clinicians and scientists, and aims to stimulate further discussion about this diverse and fascinating disease. "...contains a vast amount of information on the disease, its prevalence, signs and symptoms, diagnositc tests and treatment options. The book's format makes it quick and simple to find out what you need to know, and its size would make it easy to take to work for use in practice [...] invaluable for anyone working with patients with the disease." Emma Vincent, Nursing Standard

Download or read book Chronic Obstructive Pulmonary Disease Exacerbations written by Jadwiga A. Wedzicha and published by CRC Press. This book was released on 2008-09-22 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chronic Obstructive Pulmonary Disease Exacerbations covers the definition, diagnosis, epidemiology, mechanisms, and treatment associated with COPD exacerbations. This text also addresses imaging and how it plays a pivotal role in the diagnosis and study of exacerbations.Written by today's top experts, Chronic Obstructive Pulmonary Disease Exacerbat

Download or read book ABC of COPD written by Graeme P. Currie and published by John Wiley & Sons. This book was released on 2010-11-04 with total page 209 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chronic Obstructive Pulmonary Disease (COPD) is a progressive, largely irreversible lung condition characterised by airflow obstruction. Although cigarette smoking is the single most important risk factor in its development, other associations and risk factors are thought to have increasing relevance throughout the world. COPD is usually managed in primary care, although it is commonly under-diagnosed, and is one of the most common medical conditions necessitating admission to hospital. The second edition of the ABC of COPD provides the entire multidisciplinary team with a reliable, up-to-date and accessible account of COPD. Extensively updated by experienced clinicians - including new chapters on spirometry, inhalers, oxygen, death, dying and end of life issues - this ABC is an authoritative and practical guide for general practitioners, practice nurses, specialist nurses, medical students, paramedical staff, junior doctors, non-specialist doctors and all other health professionals working in both primary and secondary care.

Download or read book Severe Asthma written by Kian Fan Chung and published by European Respiratory Society. This book was released on 2019-06-01 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: Severe asthma is a form of asthma that responds poorly to currently available medication, and its patients represent those with greatest unmet needs. In the last 10 years, substantial progress has been made in terms of understanding some of the mechanisms that drive severe asthma; there have also been concomitant advances in the recognition of specific molecular phenotypes. This ERS Monograph covers all aspects of severe asthma – epidemiology, diagnosis, mechanisms, treatment and management – but has a particular focus on recent understanding of mechanistic heterogeneity based on an analytic approach using various ‘omics platforms applied to clinically well-defined asthma cohorts. How these advances have led to improved management targets is also emphasised. This book brings together the clinical and scientific expertise of those from around the world who are collaborating to solve the problem of severe asthma.

Download or read book Clinical Management of Chronic Obstructive Pulmonary Disease written by Thomas Similowski and published by CRC Press. This book was released on 2002-04-25 with total page 1117 pages. Available in PDF, EPUB and Kindle. Book excerpt: This reference presents a comprehensive review of the most recent strategies used to assess, treat, and manage patients in each phase of chronic obstructive pulmonary disease (COPD)-offering the latest diagnostic modalities to identify and distinguish components of COPD in earlier, more reversible stages. Contains perspectives from the World Health Organization on the epidemiology and control of COPD in Africa, South America, and Eastern Europe!

Download or read book Pharmacotherapy in Chronic Obstructive Pulmonary Disease written by Bartolome R. Celli and published by CRC Press. This book was released on 2003-12-17 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt: Placing specialists at the cutting-edge of therapeutic and biotechnological research, this reference reviews the extensive array of pharmaceutical options available for the management of patients with COPD. The book considers disease severity, dosing regimens, administration methods, and monitoring procedures, as well as medication-related side-eff

Download or read book Pharmacology of Asthma written by Clive P. Page and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 333 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume forms part of a prestigious series and covers the latest advances in our understanding of the pathophysiology and treatment of asthma. Our understanding of asthma has changed dramatically in recent years, and much of this new information is brought together in this volume written by inter nationally recognised authorities. The aim of the book is to review in depth the changing concepts of inflammatory processes in asthma and to discuss the implications for research of this common chronic disease. Many of the advances in and future therapy our understanding of asthma have originated from a pharmacological approach, and this volume highlights the promising new options for pharma cological intervention. It is hoped this book will be invaluable for research scientists and clinic ians involved in asthma research and will be a major reference resource for chest physicians and those involved in the development of novel pharmaceu tical entities. Each chapter is extensively referenced, generously illustrated with clear diagrams and photographs, and represents a state-of-the-art review of this growing area. c.P. PAGE P.l. BARNES Contents CHAPTER 1 The Pathology of Asthma: An Overview L.A. LAmNEN and A. LAmNEN. With 10 Figures ...................... 1 A. Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .. . . 1 . . . . . . . . . . . . . . . B. Methods to Investigate the Pathology of Human Asthma ............ 1 C. Bronchial Epithelium and Inflammatory Cells in Asthmatic Patients Between Attacks ........................... 2 I. Mast Cells . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .. . . 4 . . . . . . . . . . . . . . II. Eosinophils ............................................... 7 III. Neutrophils.............................................. 10 D. Bronchial Epithelial Inflammation During an Asthma Attack. . . . . .. . 10 E. Epithelial Regeneration .... . . . . . . . . . . . . . . . . . . . . . . .. . . 12 . . . . . . . . .

Download or read book Advances in Pulmonary Drug Delivery written by Philip Chi Lip Kwok and published by CRC Press. This book was released on 2016-12-19 with total page 201 pages. Available in PDF, EPUB and Kindle. Book excerpt: The respiratory tract has been used to deliver biologically active chemicals into the human body for centuries. However, the lungs are complex in their anatomy and physiology, which poses challenges to drug delivery. Inhaled formulations are generally more sophisticated than those for oral and parenteral administration. Pulmonary drug development is therefore a highly specialized area because of its many unique issues and challenges. Rapid progress is being made and offers novel solutions to existing treatment problems. Advances in Pulmonary Drug Delivery highlights the latest developments in this field.

Download or read book Difficult To Treat Asthma written by Sandhya Khurana and published by Springer Nature. This book was released on 2019-08-29 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a practical, stepwise, evidence-based approach to effective management of patients with difficult to treat asthma. The impact of asthma on morbidity and healthcare utilization increases exponentially with severity. Severe refractory asthma accounts for less than 5% of all asthma. Its prevalence, however, is often overestimated as there are several other confounding factors that make asthma ‘difficult to treat’. Many novel (albeit expensive) therapies are now available and providers caring for patients with severe asthma are charged with selecting the best evidence treatment. This calls for complex and nuanced decision-making. Whether people with asthma gain and maintain control over their condition depends not only on the availability of effective drugs, but also multiple patient and healthcare provider behaviors. Therefore, now more than ever, it has become increasingly important to differentiate “difficult” from “severe refractory” asthma to allow identification of patients most likely to benefit from these therapies. This volume delves into the current understanding of mechanisms and increasingly recognized heterogeneity of this complex disease. It discusses a structured approach to identification and optimization of factors contributing to poor asthma control, including nonadherence, comorbidities and occupational/environmental triggers. The book includes ‘state of the art’ reviews on recent advances in traditional and targeted asthma therapies, as well as a glimpse into what the future may hold. Highlights include a comprehensive guide to management of severe asthma in children and pregnancy, as well as practical considerations to management of asthma based on different clinical phenotypes. Each chapter is authored by leading experts in the field who share their own clinical approach. This is an ideal guide for clinical pulmonologists and allergist/immunologists, as well as primary care providers, physician extenders in specialty practice, physicians in pulmonary/allergy training, and even industry partners.

Download or read book Pulmonary Rehabilitation written by Claudio Donner and published by CRC Press. This book was released on 2020-07-14 with total page 526 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pulmonary rehabilitation programmes are a fundamental part of the clinical management of patients with chronic respiratory diseases. This comprehensive reference book places pulmonary rehabilitation within the wider framework of respiratory disease. Now in six parts, it includes new sections on the development of PR as a discipline, global perspectives on quality control, new chapters on early PR post exacerbation and personalized rehabilitation, innovative approaches to exercise, PR in interstitial lung disease and lung transplantation, and the latest research into the application of music, dance and yoga. Key Features Global contributions compare practice around the world where differences have developed. New six Part structure covers new approaches to exercise testing, interstitial lung diseases and other diseases, and add-on interventions drawing on new technologies. Contains recommendations of the large collaborative ERS/ATS task forces on guidelines for PR as well as suggested policies for its implementation and use. Covers the important topic of balance impairment as a focus of rehabilitation for the at-risk patient and a new chapter on monitoring physical activity. The voices of patients and caregivers describe the impact of chronic respiratory disease on their lives. Features an exclusive chapter on COVID-19 that discusses the short- and long-term pathophysiological consequences, provides information about the potential role of physiotherapy in the management of hospitalized patients with confirmed or suspected COVID-19, and details on who, where, and how to deliver programs to COVID-19 and non COVID-19 patients in the lockdown and post lockdown era.

Download or read book Advances in Asthma written by Akihito Yokoyama and published by Springer. This book was released on 2018-12-18 with total page 189 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides discussions on bronchial asthma from a clinical perspective, focusing on the recent studies on its pathophysiology, diagnosis and treatment. It also explores the lastest findings regarding the phenotypes and endotypes of asthmatic patients, making it of particular interest to those involved with non-eosinophilic asthma and eosinophilic asthma. Further, it discusses the importance of ILC 2 in eosinophilic asthma, and the accumulated results from the forced oscilliation technique and periostin that are actively practiced in Japan. As some aspects of diagnosis and treatment are different in Western and Asian countries, it is important that the data is disseminated around the globe. The clinical questions addressed by the authors are critical and thought provoking, while the questions raised by the editors are instructive, informative and provide new perspectives on unresolved issues. This book appeals to wide readership from beginning learners to physicians in clinical practice and scholars engaging in basic research.

Download or read book Allergy and Asthma written by and published by Springer. This book was released on 2019-06-25 with total page 1001 pages. Available in PDF, EPUB and Kindle. Book excerpt: Allergy and Asthma: The Basics to Best Practices is intended to serve as a single comprehensive reference covering all needed knowledge of allergic diseases. Allergy is a unique and distinctive area of medicine wherein learning the fundamentals requires gathering information from various different disciplines. Allergic diseases affect various organ systems and the practice of a wide range of physicians from otolaryngologists, and pulmonologists, to gastroenterologists, dermatologists, and ophthalmologists. Clinicians and trainees alike will benefit from a resource that introduces the basic concepts, as well as providing comprehensive, consistently up-to-date instruction on intermediate and advanced conditions, research, and treatment strategies. The book is divided into nine sections and is written by some of the foremost experts in the field. Allergy and Asthma opens with an introduction which covers the epidemiology of allergic diseases, fundamentals of allergy and immunology, and a thorough grounding of different types of allergens. Early sections address allergic upper airway diseases, allergic skin diseases, and asthma in detail, using a structured, consistent format from chapter to chapter to provide continuity and ease of reference. Later sections thoroughly cover various food allergies, insect allergies, drug allergy, anaphylaxis, and utilize ample tables and illustrations to provide additional learning tools for the reader. This major reference not only provides basic knowledge on diagnosing and treating allergies, but moves beyond these basics to emphasize using a systematic approach to working up and treating a patient. A variety of techniques used in diagnosing asthma and allergy will be examined, of which include prick skin tests, in-vitro testing, patch testing and non-conventional allergy tests. Concluding this book are sections dedicated to management, therapeutic strategies of allergy and asthma, with a look to future research directions for this unique field. Physicians and residents in allergy and immunology, pulmonology, otolaryngology, gastroenterology, dermatology, ophthalmology and other specialties will find the work of value in enhancing their practice and studies. Researchers in a range of areas especially immunology and food science will also find this text to be a compelling and reliable resource.

Download or read book Inhaled Medicines written by Stavros Kassinos and published by Academic Press. This book was released on 2021-02-05 with total page 438 pages. Available in PDF, EPUB and Kindle. Book excerpt: Inhaled medicines are widely used to treat pulmonary and systemic diseases. The efficacy and safety of these medicines can be influenced by the deposited fraction, the regional deposition pattern within the lungs and by post-depositional events such as drug dissolution, absorption and clearance from the lungs. Optimizing performance of treatments thus requires that we understand and are able to quantify these product and drug attributes. Inhaled Medicines: Optimizing Development through Integration of In Silico, In Vitro and In Vivo Approaches explores the current state of the art with respect to inhalation drug delivery, technologies available to assess product performance, and novel in silico methods now available to link in vitro product performance to clinical performance. Recent developments in the latter field, especially the prospect of integration of three-dimensional Computational Fluid Particle Methods (3D-CFPD) with physiologically based pharmacokinetic (PBPK models), unlocks the potential for in silico population studies that can help inform and optimize treatment and product development strategies. In this highly multidisciplinary field, where progress occurs at the intersection of several disciplines of engineering and science, this work aims to integrate current knowledge and understanding and to articulate a clear vision for future developments. ? Considers the healthcare needs driving the field, and where inhaled drugs could have the maximum impact ? Gives a concise account of the state of the art in key areas and technologies such as device and formulation technologies, clinically relevant in vitro performance assessment, medical imaging, as well as in silico modelling and simulation ? Articulates how the combination of in vitro product performance data, medical imaging and simulations technologies in the framework of large scale in silico pre-clinical trials could revolutionize the field ? Provides systematic and thorough referencing to sources offering a more-in-depth analysis of technical issues