Download or read book Adsorption and Activation of Carbn Monoxide at Palladium Surfaces written by Paul Vincent McKinney and published by . This book was released on 1931 with total page 28 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Air Quality Criteria for Particulate Matter written by National Center for Environmental Assessment (Research Triangle Park, N.C.) and published by . This book was released on 1996 with total page 1100 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Integration of Pharmaceutical Discovery and Development written by Ronald T. Borchardt and published by Springer Science & Business Media. This book was released on 2006-01-19 with total page 627 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the late 1980s, it became painfully evident to the pharmaceutical industry that the old paradigm of drug discovery, which involved highly segmented drug - sign and development activities, would not produce an acceptable success rate in the future. Therefore, in the early 1990s a paradigm shift occurred in which drug design and development activities became more highly integrated. This new str- egy required medicinal chemists to design drug candidates with structural f- tures that optimized pharmacological (e. g. , high affinity and specificity for the target receptor), pharmaceutical (e. g. , solubility and chemical stability), bioph- maceutical (e. g. , cell membrane permeability), and metabolic/pharmacokinetic (e. g. , metabolic stability, clearance, and protein binding) properties. Successful implementation of this strategy requires a multidisciplinary team effort, incl- ing scientists from drug design (e. g. , medicinal chemists, cell biologists, en- mologists, pharmacologists) and drug development (e. g. , analytical chemists, pharmaceutical scientists, physiologists, and molecular biologists representing the disciplines of pharmaceutics, biopharmaceutics, and pharmacokinetics/drug metabolism). With this new, highly integrated approach to drug design now widely utilized by the pharmaceutical industry, the editors of this book have provided the sci- tific community with case histories to illustrate the nature of the interdisciplinary interactions necessary to successfully implement this new approach to drug d- covery. In the first chapter, Ralph Hirschmann provides a historical perspective of why this paradigm shift in drug discovery has occurred.
Download or read book Platform Technologies in Drug Discovery and Validation written by and published by Academic Press. This book was released on 2017-11-21 with total page 692 pages. Available in PDF, EPUB and Kindle. Book excerpt: Platform Technologies in Drug Discovery and Validation, Volume 50, the latest release in the Annual Reports in Medicinal Chemistry series, provides timely and critical reviews of important topics in medicinal chemistry, with an emphasis on emerging topics in the biological sciences. Topics covered in this new volume include DELT, Oligos: ASO, siRNA, CRISPR, Micro-fluidic chemistry, High throughput screening, Kinase-centric computational drug development, Virtual Screening, Phenotypic screening, PROTACS, Chemical Biology, Fragment-based lead generation, Antibody-Drug Conjugates, Antibody-recruiting small molecules, Deuteration, and Peptides. - Unique for its treatment of platform technologies for medicinal chemistry and target validation - Provides a single, rich volume that summaries a broad spectrum of expertise relevant to the field - Presents state-of-the-art summaries of platform technologies
Download or read book Communicating Chemistry written by Patrick D. Bailey and published by Royal Society of Chemistry. This book was released on 1999 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt: Communication skills are an essential part of all university degree courses, and chemistry is no exception. The aspects of communication skills identified in this book are: * Information retrieval * written delivery * visual delivery * oral delivery * team work and * problem solving Material includes background information for tutors and a detailed tutor's guide, as well as suggestions for sources of extra material or alternative ways of running the exercise. Trialled at several institutions, this book can be used as a modular text, or as a set of "stand alone" exercises. It is aimed at students in the penultimate year of a chemistry degree.
Download or read book Skin Decontamination written by Hanjiang Zhu and published by Springer Nature. This book was released on 2019-09-26 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: The skin is the first line of defense against chemical warfare agents including nerve agents and toxic industrial chemicals, providing a possible barrier or delay to systemic distribution. However, some chemicals act directly on the skin including vesicants sulfur mustard and corrosive compounds such as strong acids or bases, and do not have to gain access to systemic circulation to cause extensive skin damage. Early and rapid skin decontamination is extremely important following exposure to chemical warfare agents and toxic industrial chemicals because it decreases serious skin damage to the patient and, potentially, their doctor. This multi-authored international text pulls together a century of decontamination research and helps the reader expedite solutions that will decrease morbidity and mortality. Complete with dozens of hiqh quality photographs and illustrations, Skin Decontamination aids industrial hygiene, dermatology, occupational physicians and those involved in the public health arena.
Download or read book The Miles Davis Reader written by Frank Alkyer and published by Hal Leonard Corporation. This book was released on 2007 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Interviews and features from Downbeat Magazine
Download or read book Studies on Periodontal Disease written by Daisuke Ekuni and published by Springer Science & Business Media. This book was released on 2014-01-09 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: The chapters of Studies on Periodontal Disease comprise four parts. Part 1 provides basic sciences from the general to the particular. The findings of cell culture and animal models supply the mechanism between periodontal disease and oxidative stress. In part 2, human clinical studies are mainly addressed. The effects of periodontal therapy on circulating oxidative stress are also discussed. The relationships between periodontal disease and systemic diseases are examined in part 3. The involvement of oxidative stress and inflammation are discussed through in vivo and in vitro study results. Part 4 discusses future strategies, including the effects of antioxidants and nutrition on periodontal disease. This thorough examination of the relationship between oxidative stress and periodontal disease is essential reading for researchers in oxidative stress and periodontal clinicians, alike.
Download or read book Blood of the Dawn written by Claudia Salazar Jiménez and published by Deep Vellum Publishing. This book was released on 2016-11-14 with total page 78 pages. Available in PDF, EPUB and Kindle. Book excerpt: This novel follows three women whose lives intertwine and are ripped apart during what’s known as “the time of fear” in Peruvian history when the Shining Path militant insurgency was at its peak. The novel rewrites the armed conflict in the voice of women, activating memory through a mixture of politics, desire, and pain in a lucid and brutal prose.
Download or read book Pesticides in Urban Environments written by Kenneth D. Racke and published by . This book was released on 1993 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of a symposium held in San Francisco in April 1992. The urban environment discussed includes homes, yards, gardens, public parks, golf courses, and restaurants. Some common products for the urban market are turf pesticides, termiticides, home and garden pesticides, indoor pesticides, and rodenticides. The papers are divided into five sections, each focusing on a different facet of urban pesticide use: pests and pesticides, dissipation of pesticides, mobility of pesticides, urban pesticides and humans, and urban pesticides and nontarget animals. Annotation copyright by Book News, Inc., Portland, OR
Download or read book Nanotechnology in Catalysis 3 written by Bing Zhou and published by Springer Science & Business Media. This book was released on 2004 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Based on the first and second symposia on Nanotechnology in Catalysis which were held in spring 2001 at the ACS 221st National Meeting in San Diego, CA, and in fall 2002 at the ACS 224th National Meeting in Boston, MA."--Pref.
Download or read book Microbial Metabolic Engineering written by Christine Nicole S. Santos and published by Humana Press. This book was released on 2019-02-21 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume covers a wide array of topics that will aid researchers in the task of engineering complex biological systems. This book is divided into three parts: Part One discusses the discovery and identification of relevant biosynthetic pathways for engineering; Part Two looks at the development of genetic tools for manipulating enzymes, biosynthetic pathways, and whole genomes; and Part Three covers the characterization of engineered microbes using targeted and global systems biology tools, as well as in silico models. Chapters explore topics such as leveraging enzyme promiscuity to construct novel biosynthetic pathways; assembling combinatorial multigene pathways for rapid strain optimization; applying 'omics technologies for identifying bottlenecks; and engineering nontraditional host organisms like cyanobacterium and Yarrowia lipolytica. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting edge and authoritative, Microbial Metabolic Engineering: Methods and Protocols is a valuable resource for researchers and scientists interested in engineering and optimizing microbes for a variety of biotechnological applications.
Download or read book Masters Theses in the Pure and Applied Sciences written by Wade H. Shafer and published by Springer. This book was released on 1976 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: Masters Theses in the Pure and Applied Sciences was first conceived, published, and dis· seminated by the Center for Information and Numerical Data Analysis and Synthesis (CINDAS) *at Purdue University in 1957, starting its coverage of theses with the academic year 1955. Beginning with Volume 13, the printing and dissemination phases of the ac· tivity were transferred to University Microfilms/Xerox of Ann Arbor, Michigan, with the thought that such an arrangement would be more beneficial to the academic and general scientific and technical community. After five years of this joint undertaking we had concluded that it was in the interest of all concerned if the printing and distribution of the volume were handled by an international publishing house to assure improved service and broader dissemination. Hence, starting with Volume 18, Masters Theses in the Pure and Applied Sciences has been disseminated on a worldwide basis by Plenum Publishing Corporation of New York, and in the same year the coverage was broadened to include Canadian universities. All back issues can also be ordered from Plenum. We have reported in Volume 20 (thesis year 1975) a total of 10,374 theses titles from 28 Canadian and 239 United States universities. We are sure that this broader base for theses titles reported will greatly enhance the value of this important annual reference work. The organization of Volume 20 is identical to that of past years. It consists of theses titles arranged by discipline and by university within each discipline.
Download or read book Effect of Porous Structure on Carbon Activation written by Colorado. University. Chemical Engineering Department and published by . This book was released on 1971 with total page 108 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Adsorption Surface Area and Porosity written by Sidney John Gregg and published by . This book was released on 1967 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Active Carbon written by John W. Hassler and published by . This book was released on 1951 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt:
