Download or read book Adrenomedullin written by Alfredo Martínez and published by IOS Press. This book was released on 1998 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: Adrenomedullin is a recently discovered peptide hormone which involved in many physiological and pathological processes. This book reviews all the information available on this intriguing molecule, covering topics as diverse as blood pressure regulation, growth of tumours and normal cells, the central nervous system, and comparative studies from sharks to mammals. An international group of experts has contributed to this volume which will be of interest to professionals, researchers, and those who will benefit from a broad review of the literature and the main trends in adrenomedullin research.

Download or read book Adrenomedullin in Cardiovascular Disease written by Toshio Nishikimi and published by Springer Science & Business Media. This book was released on 2005-07-25 with total page 227 pages. Available in PDF, EPUB and Kindle. Book excerpt: Adrenomedullin in Cardiovascular Disease is an up-to-date review of the most relevant aspects of adrenomedullin. It encompasses a broad range of fields including biochemistry, molecular biology, physiology, pharmacology, pathophysiology of cardiovascular disease and clinical applications of adrenomedullin to cardiovascular disease.

Download or read book Innovative Medicine written by Kazuwa Nakao and published by Springer. This book was released on 2015-10-13 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is devoted to innovative medicine, comprising the proceedings of the Uehara Memorial Foundation Symposium 2014. It remains extremely rare for the findings of basic research to be developed into clinical applications, and it takes a long time for the process to be achieved. The task of advancing the development of basic research into clinical reality lies with translational science, yet the field seems to struggle to find a way to move forward. To create innovative medical technology, many steps need to be taken: development and analysis of optimal animal models of human diseases, elucidation of genomic and epidemiological data, and establishment of “proof of concept”. There is also considerable demand for progress in drug research, new surgical procedures, and new clinical devices and equipment. While the original research target may be rare diseases, it is also important to apply those findings more broadly to common diseases. The book covers a wide range of topics and is organized into three complementary parts. The first part is basic research for innovative medicine, the second is translational research for innovative medicine, and the third is new technology for innovative medicine. This book helps to understand innovative medicine and to make progress in its realization.

Download or read book Handbook of Neuroendocrinology written by George Fink and published by Academic Press. This book was released on 2012 with total page 895 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuroendocrinology underpins fundamental physiological, molecular, biological, and genetic principles such as the regulation of gene transcription and translation. This handbook highlights the experimental and technical foundations of each area's major concepts and principles.

Download or read book Cellular Mechanisms for the Adrenomedullin Control of Mesangial Growth Apoptosis and Matrix written by Narayanan Parameswaran and published by . This book was released on 1999 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Endothelium written by Michel Félétou and published by Morgan & Claypool Publishers. This book was released on 2011 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: The endothelium, a monolayer of endothelial cells, constitutes the inner cellular lining of the blood vessels (arteries, veins and capillaries) and the lymphatic system, and therefore is in direct contact with the blood/lymph and the circulating cells. The endothelium is a major player in the control of blood fluidity, platelet aggregation and vascular tone, a major actor in the regulation of immunology, inflammation and angiogenesis, and an important metabolizing and an endocrine organ. Endothelial cells controls vascular tone, and thereby blood flow, by synthesizing and releasing relaxing and contracting factors such as nitric oxide, metabolites of arachidonic acid via the cyclooxygenases, lipoxygenases and cytochrome P450 pathways, various peptides (endothelin, urotensin, CNP, adrenomedullin, etc.), adenosine, purines, reactive oxygen species and so on. Additionally, endothelial ectoenzymes are required steps in the generation of vasoactive hormones such as angiotensin II. An endothelial dysfunction linked to an imbalance in the synthesis and/or the release of these various endothelial factors may explain the initiation of cardiovascular pathologies (from hypertension to atherosclerosis) or their development and perpetuation. Table of Contents: Introduction / Multiple Functions of the Endothelial Cells / Calcium Signaling in Vascular Cells and Cell-to-Cell Communications / Endothelium-Dependent Regulation of Vascular Tone / Conclusion / References

Download or read book Cancer Research written by and published by . This book was released on 2007-03 with total page 1084 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The CGRP Family written by David Poyner and published by CRC Press. This book was released on 1999-10-01 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is based on presentations given at CGRP '98, the Third International Meeting on CGRP and related peptides held in the UK in May 1998. The principal speakers have each contributed a chapter and many of the short and poster communications will also be found here. This book follows from the tradition set by the First and Second Meetings in 1

Download or read book Heart Failure written by Shigetake Sasayama and published by . This book was released on 1996 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Neuroscience Letters written by and published by . This book was released on 1996 with total page 516 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Chemical Abstracts written by and published by . This book was released on 2002 with total page 2540 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Endocrine Pancreas and Regulation of Metabolism written by and published by . This book was released on 2001 with total page 1284 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive and authoritative reference work examines the role of the endocrine pancreas in the regulation of fat, protein, and carbohydrate metabolism. The effects of hormones are broadly examined with emphasis on the gene, the cell and the organism as a whole. The functions of the pancreatic hormones in the integrated response of the body to various physiologic challenges are discussed. Following a general introduction by Sir Philip Randle, the book is divided into four sections:1. The Islets of Langerhans, 2. Target Tissues for Metabolic Regulatory Hormones, 3. Influence of Hormones Acting as Acute Metabolic Regulators on the Actions of Islet Hormones, and 4. Integrated Hormonal Responses to Physiological Challenges. The fourth part covers many interesting conditions such as pregnancy, aging, obesity, hypoglycemia, insulin-dependent diabetes mellitus, and starvation.

Download or read book The Endocrine System written by P. Michael Conn and published by . This book was released on 2001 with total page 1282 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive and authoritative reference work examines the role of the endocrine pancreas in the regulation of fat, protein, and carbohydrate metabolism. The effects of hormones are broadly examined with emphasis on the gene, the cell and the organism as a whole. The functions of the pancreatic hormones in the integrated response of the body to various physiologic challenges are discussed. Following a general introduction by Sir Philip Randle, the book is divided into four sections:1. The Islets of Langerhans, 2. Target Tissues for Metabolic Regulatory Hormones, 3. Influence of Hormones Acting as Acute Metabolic Regulators on the Actions of Islet Hormones, and 4. Integrated Hormonal Responses to Physiological Challenges. The fourth part covers many interesting conditions such as pregnancy, aging, obesity, hypoglycemia, insulin-dependent diabetes mellitus, and starvation.

Download or read book Journal of the National Cancer Institute written by and published by . This book was released on 2002 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Summaries of papers" contained in the journal accompany each issue, 19--

Download or read book Microcirculation written by Ronald F. Tuma and published by Academic Press. This book was released on 2011-04-28 with total page 999 pages. Available in PDF, EPUB and Kindle. Book excerpt: This reference is a volume in the Handbook of Physiology, co-published with The American Physiological Society. Growth in knowledge about the microcirculation has been explosive with the field becoming fragmented into numerous subdisciplines and subspecialties. This volume pulls all of the critical information into one volume. Meticulously edited and reviewed. Benefit: Provides investigators a unique tool to explore the significance of their findings in the context of other aspects of the microcirculation. In this way, the updated edition has a direct role in helping to develop new pathways of research and scholarship Highlights the explosive growth in knowledge about the microcirculation including the biology of nitric oxide synthase (NOS), endothelial cell signaling, angiogenesis, cell adhesion molecules, lymphocyte trafficking, ion channels and receptors, and propagated vasomotor responses. Benefit: Microcirculatory biology has become fragmented into numerous sub-disciplines and subspecialties, and these reference reintegrates the information in one volume

Download or read book European Journal of Endocrinology written by and published by . This book was released on 2002 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Endocrinology of the Heart in Health and Disease written by Jonathan C. Schisler and published by Academic Press. This book was released on 2016-10-19 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: Endocrinology of the Heart in Health and Disease: Integrated, Cellular, and Molecular Endocrinology of the Heart covers the traditional concepts of cardio-endocrinology, the role of the various hormone systems, both in health and disease, therapeutic implications, and other recent advances in the various fields represented. The book explores how cardiac hormones are changed in various cardiac pathologies and the recent success that has been uncovered in their therapeutic use. Additional focus is placed on how the heart responds both physiologically and pathophysiologically to a plethora of circulating hormones, reinforcing the importance of the heart as a target of numerous endocrine systems, such as the brain, renal, and adipose. Significant advances have come from basic, clinical, and translational research from a multiplicity of investigators with diverse backgrounds. The book features over 200 photomicrographs, diagrams of molecular relationships, and tables that complement and support the text. It is aimed at a wide audience, including graduate students and post-doctoral fellows in a wide array of biomedical departments and PhD programs (e.g. Pathology, Physiology, Genetics, Pharmacology, Molecular Biology, and Cell Biology) related to the endocrine and cardiovascular sciences curricula, as well as medical residents in pathology, laboratory medicine, internal medicine, and cardiology. Develops the concept of the heart as both an endocrine organ and an endocrine target, exploring the endocrine function of the heart in both health and disease Explains how the levels of several cardiac hormones are changed in various cardiac pathologies and how some hormones can be used therapeutically Offers a single resource on cardio-endocrine disease which collates and curates the wide range of advances being made in the areas of molecular biology, biochemistry, physiology, and pathology