Download or read book Exocyclic DNA Adducts in Mutagenesis and Carcinogenesis written by H. Bartsch and published by . This book was released on 1999 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: The use of exocyclic adducts as biomarkers offers a promising tool in studies of cancer etiology and prevention, particularly for human neoplasias in which the causative factors and mechanisms are still poorly understood. Presentations at an international conference, which resulted in this volume, comprise a comprehensive treatise on the current state of the art and scientific information on exocyclic DNA adducts. The volume includes sections on ultra sensitive detection methods, formation from exogenous and endogenous sources, DNA repair, physical chemical approaches to structural elucidation, and use as biomarkers and their role in mutagenesis and carcinogenesis.
Download or read book Surface Active Ethylene Oxide Adducts written by N. Schönfeldt and published by Elsevier. This book was released on 2013-09-17 with total page 969 pages. Available in PDF, EPUB and Kindle. Book excerpt: Surface Active Ethylene Oxide Adducts covers the fundamental problems associated with the surface active ethylene oxide adduct. This book contains six chapters that consider the progress on modifications of ethylene oxide adducts. The opening chapters examine the preparation and industrial application of ethylene oxide adducts. These chapters provide a formulation based on the starting materials and divides the ethylene oxide adducts in different classes according to the bond between the hydrophobic and the hydrophilic part of the molecule. The next chapters describe the physical, chemical, and functional properties of these adducts. These chapters also look into the biodegradability and industrial uses of ethoxylated products, with an emphasis on their applications to the mineral oil industry. These topics are followed by discussions of the chemical modifications of ethylene oxide adducts, including etherification of the terminal hydroxyl group with aliphatic or cyclic, hydrophobic radicals and carboxymethylation of adducts. The final chapter focuses on the analytical methods used in the industrial control laboratory an in product analysis. This book is intended primarily for laboratory chemists, plant chemists, and chemical engineers.
Download or read book Environmental Health Perspectives written by and published by . This book was released on 2004 with total page 1252 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Technologies for Detection of DNA Damage and Mutations written by G.P. Pfeifer and published by Springer Science & Business Media. This book was released on 1996-07-31 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: ''Useful and timely.'' ---Mutagenesis ''Of considerable value.'' ---Journal of Medical Genetics ''Quite readable....a comprehensive overview....perfectly covers the needs of those researchers who have to decide on the best strategy to identify damage or mutations at the molecular level.'' ---Trends in Cell Biology ''The formats of the presentations are uniform and ample and up-to-date references are provided at the end of each chapter...will be welcomed by postgraduate researchers of all ages and should retain its usefulness for a long time.'' ---Endeavour, 21(4), 1997 This important resource thoroughly reviews a wide range of techniques used in mutagenesis research-ranging from established techniques to recently developed methodologies-based on the polymerase chain reaction. DNA damage analysis, DNA repair assays, and mutation detection are a few of the techniques featured. Chapters present detailed experimental protocols benefiting researchers and students in the fields of toxicology, biotechniques, molecular biology, photobiology, medical genetics, and oncology.
Download or read book Plant Polyphenols 2 written by Georg G. Gross and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 911 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume summarizes current research on the influence of plant polyphenols on human health, promoting collaboration between chemists and biologists to improve our understanding of their biological significance, and expanding the possibilities for their use.
Download or read book Catecholamines Bridging Basic Science with Clinical Medicine written by and published by Academic Press. This book was released on 1997-10-20 with total page 1129 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume in Advances in Pharmacology focuses on all aspects of catecholamine research, from very basic to medical. It is broad based and covers many areas within physiology and medicine.
Download or read book Advances in Chromatography Volume 49 written by Eli Grushka and published by CRC Press. This book was released on 2016-04-19 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Chromatography is a venerable series that has reported on the latest state-of-the-art developments in the field for the past four decades. The newest installment, Volume 49, continues the tradition of compiling the work of expert contributors who present timely and cutting edge reviews of current and emerging methods and applications in
Download or read book Toxicological Profile for Creosote coal Tar and Wood Coal Tar and Coal Tar Pitch written by and published by . This book was released on 1994 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Toxicological Profile for Wood Creosote Coal Tar Creosote Coal Tar Coal Tar Pitch and Coal Tar Pitch Volatiles written by and published by . This book was released on 1996 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Nitroarenes written by Paul C. Howard and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: Prior to 1979, consideration of the problem of the carcinogenicity of the aromatic amine class of chemicals took place primarily in poster sessions and symposia of annual meetings of the American Association for Cancer Research and analogous international associations. In November 1979 the first meeting concerned with the aromatic amines was held in Rockville, Haryland under primary sponsorship of the National Cancer Institute. The proceedings from this meeting were published as Monograph 58 of the Journal of the National Cancel' Institute in 1981. The second meeting in this series, the Second International Conference on N-Substituted Aryl Compounds, was held in March/April of 1982 in Hot Springs, Arkansas. The National Cancer Institute and The National Center for Toxicological Research were the primary sponsors of this meeting. The proceedings were published as Volume 49 of the journal En-vil'onmental Health Perspectives in 1983. The third meeting in this series was held in April of 1987 at the Dearborn Hyatt in Dearborn, Michigan. The principal sponsor of this meeting was the Heyer L. Pre ntis Comprehensive Cancer Center of Metropolitan Detroit. The proceedings, Carcinogenic and Mutagenic Responses to Aromatic Amines and Nitroal'enes, were published in 1987 by Elsevier Press. The fourth meeting was held in Cleveland, Ohio, on July 15-19, 1989.
Download or read book Synchrotron Radiation in Structural Biology written by R. Sweet and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: The development of synchrotron radiation (SR) as a research tool was driven largely by the needs of materials scientists and solid-state physi cists. However, the availability of SR has extended significantly the capa bility of scientists who study biological structure with radiation. This volume contains some of the results reported at a symposium held at Brookhaven National Laboratory in May 1988 to discuss the application of synchrotron radiation to structural biology. We are grateful for financial support from the u. s. Department of Energy, the National Institutes of Health, Genentech, Inc., Blake Indus tries, Inc., Evans and Sutherland Co., The Upjohn Company, Eli Lilly and Company, Enraf-Nonius Service Corp., and Associated Universities, Inc. We warmly thank Ms. Nancy Siemon for her tireless efforts with correspondence and the manuscripts for this symposium volume. Symposium Committee: Robert M. Sweet, Chair Malcolm S. Capel Benno P. Schoenborn John C. Sutherland Elizabeth C. Theil Stephen W. White Avril D. Woodhead Helen Z. Kondratuk, Coordinator v CONTENTS An Introduction to the Symposium . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 R. M. Sweet SYMPOSIUM LECTURE Developments in X-ray Technology and Their Contribution to Structural Biology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 H. E. Huxley SOME OF THE SYNCHROTRON FACILITIES FOR BIOLOGICAL STRUCTURAL STUDIES MacChess - A Macromolecular Diffraction Resource at the Cornell High Energy Synchrotron Source . . . . . . . . . . . . . . . . . . . 15 W. Schi1dkamp, K. Moffat, B. Batterman, D. Bilderback, T-Y. Teng, A. LeGrand and D. Szebenyi Facilities Available for Biophysics Research at the Stanford Synchrotron Radiation Laboratory. . . . . . . . . . . . . . . . . . . . . 19 R. P."
Download or read book Draft Toxicological Profile for Wood Creosote Coal Tar Creosote Coal Tar Coal Tar Pitch and Coal Tar Pitch Volatiles written by and published by . This book was released on 2000 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book How Tobacco Smoke Causes Disease written by United States. Public Health Service. Office of the Surgeon General and published by . This book was released on 2010 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
Download or read book Gastrointestinal Oncology written by James L. Abbruzzese and published by Oxford University Press. This book was released on 2003-10-23 with total page 938 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 74 chapters, Gastrointestinal Oncology brings together a diverse group of specialists to provide the most authoritative, up-to-date and encyclopedic volume currently available on the subject. The first part of this text introduces a series of concepts and topics taht are important to gastrointestinal malignancies in general. These topics include epidemiologic principles, prevention, screening, familial GI cancers, developmental and molecular biology, pathobiology, general therapeutic principles, emerging therapies, and palliative care. The second part of the book covers each of the specific cancers affecting the human gastrointestinal tract. These chapters are introduced by state of the art discussions outlining our current understanding of the pathobiology and molecular biology relevant to each cancer. Subsequent sections describe the multidisciplinary management of specific clinical situations. By organizing the treatment-related chapters around clinical scenarios, the reader will readily find the information necessary to effectively manage the complex clinical situations encountered by patients with gastrointestinal malignancies.
Download or read book Acetaldehyde Related Pathology written by Derek J. Chadwick and published by John Wiley & Sons. This book was released on 2007-04-30 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: Part of the prestigious Novartis Foundation, this is the first book to review the pathology associated with acetaldehyde, a known toxic agent found in cigarette smoke and other pollutants and derived from ingested alcohol, amongst other sources. In the body, acetaldehyde affects several tissues, particularly the brain and liver, causing various diseases, including cancer, alcoholic liver disease and Alzheimer’s. Acetaldehyde-Related Pathology describes the toxic effects of acetaldehyde at the tissue and cellular levels, reviewing enzyme biochemistry, transgenic mouse models of alcohol dehydrogenase mutants, and the cell-signalling pathways implicated in alcohol-related pathology. It explores the mechanisms of acetaldehyde-induced damage to tissues, often a first step in carcinogenesis, including the oral cavity, the human airway, and the GI tract. The book considers pharmacological strategies and treatments for reducing oral and intestinal acetaldehyde. Acetaldehyde-Related Pathology features in-depth, round-table discussions by an international array of scientists from major laboratories worldwide involved in studies of acetaldehyde-related pathology. This book is essential reading for anyone interested in the effects of this compound - pathologists, biochemists, toxicologists, cell and molecular biologists.
Download or read book Current Organic Chemistry written by and published by . This book was released on 1998-07 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Use of Small Fish Species in Carcinogenicity Testing written by and published by . This book was released on 1984 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt:
