Download or read book Acute Kidney Injury Basic Research and Clinical Practice written by X. Ding and published by Karger Medical and Scientific Publishers. This book was released on 2018-01-23 with total page 175 pages. Available in PDF, EPUB and Kindle. Book excerpt: Acute Kidney Injury (AKI) is a complex syndrome that is prevalent among hospitalized patients. In recent years, occurrence of AKI events has risen due to a growing susceptibility of fragile and elderly subjects and an increase in the use of complex procedures such as cardiovascular surgery and imaging techniques. Exposure to potentially nephrotoxic drugs, such as new chemotherapeutic agents, is also proving to be a cause of AKI. This book summarizes recent advances in various settings. A reappraisal of current definitions and staging classifications for AKI in the literature is followed by a description of new criteria for identifying patients at risk and characterizing early kidney damage by using biomarkers. Other important topics include the sequelae of AKI and AKI in special populations such as children, the elderly, and those with cancer. The effects of AKI and its consequences on healthcare expenditures are also addressed from several perspectives. AKI management requires the cooperation of different specialists to optimize outcomes. This book is thus a perfect tool not only for nephrologists, but for every specialist involved in the complicated endeavor of improving patient care.

Download or read book Continuous Renal Replacement Therapy written by John A. Kellum and published by Oxford University Press. This book was released on 2016 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: Continuous Renal Replacement Therapy provides concise, evidence-based, bedside guidance for the management of critically ill patients with acute renal failure, offering quick reference answers to clinicians' questions about treatments and situations encountered in daily practice.

Download or read book Diagnostics Risk Factors Treatment and Outcomes of Acute Kidney Injury in a New Paradigm written by Wisit Cheungpasitporn and published by MDPI. This book was released on 2020-12-10 with total page 574 pages. Available in PDF, EPUB and Kindle. Book excerpt: Acute kidney injury (AKI) is a frequent clinical syndrome among hospitalized patients, independently associated with both short- and long-term mortality. Previous investigations attempted to identify effective interventions to prevent AKI or promote kidney function recovery in patients with AKI. Most were unsuccessful. Hence, additional studies are required in the field of AKI research. In this Special Issue, we are making a call to action to stimulate researchers and clinicians to submit their studies on AKI conducted in nephrology, internal medicine, critical care, and other disciplines that will provide additional knowledge and skills in the field of AKI research, ultimately to improve patient outcomes.

Download or read book Controversies in Acute Kidney Injury written by J.A. Kellum and published by Karger Medical and Scientific Publishers. This book was released on 2011-09-15 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: Acute kidney injury (AKI) is a serious and as yet incompletely understood disorder in which sudden impairment of kidney function occurs secondary to one or more of a variety of underlying conditions. This disorder is very common in (elderly) ICU patients and is associated with very high mortality. Many of those who survive suffer from permanent kidney failure and other long-term morbidities, which may include cardiovascular disease and immune dysfunction. Epidemiologic evidence suggests that AKI is not a single disease, but a syndrome comprised of multiple, often coexisting, etiologies. Being usually part of multiorgan failure syndrome, it calls for multiple organ support therapy.The publication at hand contains sections on prerenal azotemia syndromes, dying ‘of’ or ‘with’ AKI, pathophysiology of sepsis-induced acute kidney injury, developments in prevention / treatment / rehabilitation, and renal support. Reporting the latest recommendations from experts, it provides valuable information for those that are interested in understanding the disorder and its treatment options.

Download or read book ADQI Consensus on AKI Biomarkers and Cardiorenal Syndromes written by J.A. Kellum and published by Karger Medical and Scientific Publishers. This book was released on 2013-05-14 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: Associated with both acute kidney injury (AKI) and cardio-renal syndromes (CRS), new biomarkers represent both a popular area of investigation and a new opportunity for advancement of therapy. This book contains the resolutions of the most recent ADQI conferences on biomarkers in AKI (Dublin) and on cardio-renal syndromes (Venice). The first part answers specific questions about new biomarkers and their use and utility in AKI: What are the most suitable candidate molecules and physiologic measures, how solid and evidence based is the discovery phase? How can we incorporate the new biomarkers in the AKI conceptual model describing the evolution from susceptibility to insult, decreased GFR and organ death? Even if we have a positive biomarker pattern and we can identify patients at risk or patients with early or even subclinical AKI, how is this information affecting our clinical behavior and practice? The second part is dedicated to the appraisal of the current knowledge about the pathophysiological mechanisms involved in different forms of CRS: it contains contributions on the state-of-the-art knowledge and practice of CRS, particularly focusing on the pathophysiology of the five subtypes. Acute and chronic mechanisms of damage are explored in depth, with particular attention to the primacy of organ involvement and the subsequent pathways of organ crosstalk.Presenting the most recent research in the field of biomarkers, AKI and CRS, this publication is an important educational tool for advanced investigators and clinical experts, but also for students and fellows.

Download or read book Oxford Textbook of Clinical Nephrology written by Neil N. Turner and published by Oxford University Press. This book was released on 2015-10-29 with total page 3045 pages. Available in PDF, EPUB and Kindle. Book excerpt: This fourth edition of the Oxford Textbook of Clinical Nephrology builds on the success and international reputation of the publication as an important resource for the practising clinician in the field. It provides practical, scholarly, and evidence-based coverage of the full spectrum of clinical nephrology, written by a global faculty of experts. The most relevant and important reference to clinical nephrology, this is an authoritative and comprehensive textbook combining the clinical aspects of renal disease essential to daily clinical practice with extensive information about the underlying basic science and current evidence available. Each section of the textbook has been critically and comprehensively edited under the auspices of a leading expert in the field. This new edition has been significantly expanded and reapportioned to reflect developments and new approaches to topics, and includes treatment algorithms to aid and enhance patient care where possible. The fourth edition offers increased focus on the medical aspects of transplantation, HIV-associated renal disease, and infection and renal disease, alongside entirely new sections on genetic topics and clinical and physiological aspects of fluid/electrolyte and tubular disorders. The emphasis throughout is on marrying advances in scientific research with clinical management. Richly illustrated throughout in full colour, this is a truly modern and attractive edition which reinforces the Oxford Textbook of Clinical Nephrology's position as an indispensable reference work of consistent quality and reliability. Enriched and refined by careful revision, this new edition continues the tradition of excellence. This print edition of The Oxford Textbook of Clinical Nephrology comes with a year's access to the online version on Oxford Medicine Online. By activating your unique access code, you can read and annotate the full text online, follow links from the references to primary research materials, and view, enlarge and download all the figures and tables. Oxford Medicine Online is mobile optimized for access when and where you need it.

Download or read book Nephrology and Public Health Worldwide written by G.B. Silva Junior and published by Karger Medical and Scientific Publishers. This book was released on 2021-11-02 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nephrology is one of the fastest growing specialties in medicine. Nevertheless, kidney disease is one of the most serious unmet health needs in many countries. To provide healthcare access with the desirable equity worldwide, the nephrology community needs to discuss this public health issue and take part in decisions for elaboration of public health policies with more justice and equity. This book brings together key current public health problems that affect kidney function and illuminates them in contributions by an international group of nephrologists and general practitioners. The chapters review current knowledge and provide guidelines to manage these conditions and decrease the disease burden. At the end, developments in the digital era and their application to kidney disease treatment are synthesized, and a broader outlook on the future of nephrology is given. Ultimately, the publication aims to gather nephrology and public health expertise from researchers from all over the world, providing a broad vision of issues that must be discussed and overcome to guarantee a better treatment for patients with kidney diseases in the world today.

Download or read book Perioperative Kidney Injury written by Charuhas V. Thakar and published by Springer. This book was released on 2014-10-21 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt: The kidneys participate in all vital processes of the body to maintain overall homeostasis and health. When kidneys are injured during surgical interventions, metabolic and hemodynamic control is disrupted, leading to dysfunction associated with greater mortality, length of hospital stay and cost. Peri-operative Kidney Injury presents the epidemiology, risk factors, diagnosis, treatment and outcomes associated with kidney injury during the peri-operative period. Concepts and principles of care to prevent kidney complications during surgical procedures are provided to equip health care professionals along with strategies to manage acute kidney injury and associated challenges when they occur. Chapters detail diverse surgical settings, ranging from the more common, such as abdominal, cardiac and vascular surgeries, to the intricately complex, including the use of the left ventricular assist device and organ transplants. This practical and comprehensive text blends the evidence-based standards of care with cutting edge advances in the field, while also providing the reader with a peek into innovations on the horizon.

Download or read book Acute Kidney Injury written by Claudio Ronco and published by Karger Medical and Scientific Publishers. This book was released on 2007-01-01 with total page 477 pages. Available in PDF, EPUB and Kindle. Book excerpt: Acute kidney injury is defined as an abrupt change in serum creatinine and/or urine output, and a majority of patients admitted to the ICU have some evidence of the disorder. Unfortunately, treatment for this complex syndrome is as yet lacking and understanding is limited. An interdisciplinary panel of experts has contributed to this volume, illuminating some of the fundamental and complex aspects of the disorder ranging from pathophysiology to treatment, from emerging biomarkers to genetic polymorphisms. Other contributions focus on immunological issues or the many complications of acute kidney injury and co-morbid conditions encountered, covering the fundamentals as well as the latest developments. Moreover, important technical aspects of extracorporeal therapies including vascular access, anticoagulation or fluid composition are introduced, and different approaches to renal support from intermittent dialysis to continuous therapies and hybrid techniques are discussed. A description of advanced extracorporeal techniques of organ support and their role in the management of sepsis and acute kidney injury in the context of an overall strategy of multi-organ failure management concludes the discussions. This volume not only provides a practical and up-to-date summary of current knowledge and technology, but also imparts a fundamental understanding of the pathogenesis and likely future developments in this field. It also serves to challenge and re-examine the fundamental underlying assumptions we hold regarding critical illness in general and acute kidney injury in particular.

Download or read book Pharmacotherapy Handbook written by Barbara G. Wells and published by McGraw Hill Professional. This book was released on 2005 with total page 966 pages. Available in PDF, EPUB and Kindle. Book excerpt: BONE AND JOINT DISORDERS Edited by Terry L. Schwinghammer 1. Gout and Hyperuricemia 2. Osteoarthritis 3. Osteoporosis 4. Rheumatoid Arthritis CARDIOVASCULAR DISORDERS Edited by Terry L. Schwinghammer 5. Arrhythmias 6. Cardiopulmonary Resuscitation 7. Heart Failure 8. Hyperlipidemia 9.

Download or read book Hypertension from basic research to clinical practice written by Md. Shahidul Islam and published by Springer. This book was released on 2017-05-09 with total page 620 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hypertension: from basic research to clinical practice” contains a unique collection of selected chapters written by experts and enthusiasts engaged in research and treatment of hypertension, a condition that affects around a billion people in the world. The chapters describe fundamental researches at cellular and molecular levels to the science, and art of treatment of the condition in clinical practice. The topics included ranges from pathophysiology of hypertension, through monitoring of hypertension, to the treatment of hypertension in different patient categories. It contains essential background information as well as cutting edge research, and state of the art treatment alternatives in this broad field. From the beginners, and research students to the expert clinicians, and established scientists, everybody has something to learn from this book.

Download or read book Basic Principles of Critical Care Nephrology written by Nadezda Petejova and published by Nova Biomedical Books. This book was released on 2017 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Acute kidney injury (AKI) is a common diagnosis in daily clinical practice, occuring in virtually all fields of medicine. Critically ill patients are especially prone to the development of AKI due to frequent haemodynamic instability, multiple risk factors and, diagnostic and/or treatment complications. Severe AKI substantially prolongs the intensive care unit (ICU) length of stay, with increased risk of death. AKI is also a predisposing factor for multiple organ dysfunction syndrome and is usually a part of it. For these and other reasons, critical care nephrology plays an irreplaceable role in treating critically ill patients in ICUs. The current trend in medicine generally not only in critical care nephrology is to gather as much scientific knowledge as possible and in medicine, everything is interrelated. Further, knowledge of pathophysiology and understanding the causes of illness come in an era of increasing polypharmacy and the escalating side effects of drugs. The latter can cause conditions with the same clinical picture as immune system disorders, viruses and bacteria. Another issue is poisonings and drug intoxications, which are a daily issue in ICU settings. In short, the aetiological spectrum of disease has expanded. This book presents the basic principles in critical care nephrology and covers the epidemiology, pathophysiology, the most frequent syndromes, poisonings and conservative or invasive treatment options. The aim is to present an easily understandable overview using relevant scientific research results, along with the authors own practical clinical experience from the University Hospital of Ostrava in the Czech Republic. The authors believe that this textbook will be useful to physicians who have to make rapid diagnoses and decision making in daily ICU practice.

Download or read book Anatomy and Physiology written by J. Gordon Betts and published by . This book was released on 2013-04-25 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Acute Kidney Injury and Regenerative Medicine written by Yoshio Terada and published by Springer Nature. This book was released on 2020-05-14 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents up-to-date information on the clinical-pathophysiological features of acute renal injury and discusses the KDIGO diagnostic criteria, as well as novel experimental findings, including in the area of regenerative medicine. It also highlights the clinical-pathophysiological importance of AKI in clinical settings, including differential diagnoses and management of AKI. In the past, the pathology associated with sudden renal impairment was characterized as acute renal failure (ARF). However, in the 2000s, the joint efforts of specialists in fields including nephrology, intensive care medicine, and cardiovascular medicine led to the introduction of a novel concept known as acute kidney injury (AKI). As medical care progressed, patients such as high-risk elderly subjects who were not deemed to be candidates for invasive therapy came to be treated in intensive care units (ICUs). As a result, kidney injury as a subset of multiple organ failure was re-considered as AKI, especially in intensive care medicine. AKI was then proposed as a novel disease concept to emphasize the importance of early diagnosis and early intervention to improve prognosis.Presenting novel features, such as the definition of AKI, risk factors and management; biomarkers, such as neutrophil gelatinase-associated lipocalin (NGAL) and L-type fatty acid-binding protein (L-FABP); long-term outcomes of AKI; as well as renal regeneration using iPS cell, manipulation of embryonic genes, and Xenotransplanted embryonic kidney, this book is of interest to all physicians and researchers in this field around the globe.

Download or read book Aortic Diseases Involving Visceral Artery Clinical Therapeutic Management and Related Basic Research written by Xiangjiu Ding and published by Frontiers Media SA. This book was released on 2024-07-23 with total page 95 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aortic diseases (mainly including aortic dissection and aneurysm) are common but life-threatening entities. With development of surgical and endovascular techniques, treatment outcomes have been improved gradually. However, a lot of problems still require to be resolved. Aortic diseases in the region of visceral arteries are difficult to treat, especially for aortic dissection, which is usually associated with the narrow true lumen. Conventional open repair is associated with high trauma and high morbidity and mortality. Endovascular intervention has been applied in the last decade. Fenestration technique, chimney technique, and branched stent-grafts have been used for aortic aneurysms. For aortic dissection, management in the region of the visceral arteries is more complicated, and more techniques have been described. Besides these three methods, exclusion of the re-entry by vascular occluder, road block strategy, and candy-plug technique are also reported. However, these endovascular techniques vary in characteristics, procedures, and outcomes. There is no consensus on the optimal treatment for these complicated entities.

Download or read book Studies on Renal Disorders written by Toshio Miyata and published by Springer Science & Business Media. This book was released on 2010-12-17 with total page 781 pages. Available in PDF, EPUB and Kindle. Book excerpt: Conditions such as oxidative stress and hypoxia, which have a generalized impact on the oxygen metabolism, have been implicated in the genesis of kidney disease. This means that deepening our understanding of the pathobiology of oxygen metabolism in such diseases could be a fruitful path towards tangible clinical benefits. Studies in Renal Disorder collects reviews from leading researchers and clinical scientists working in exactly this field, providing an overview of the latest advances. The causal role of impaired oxygen metabolism in kidney disease has numerous clinical implications. It affects our understanding of the therapeutic benefits accruing from anti-hypertensive agents; the way we control hyperglycemia/hyperinsulinemia and hyperlipidemia; and our use of dietary approaches to the correction of obesity. The defensive mechanisms against oxidative stress, such as the Nrf2-Keap1 system, and hypoxia, such as the PHD-HIF system, have recently been explored in various cells, including kidney cells. These mechanisms include intracellular sensors for oxidative stress and hypoxia. This means that novel approaches targeting these sensors may offer clinical benefits in kidney disease in which oxidative stress and/or hypoxia is a final, common pathway.

Download or read book Recent Advances in the Pathogenesis and Treatment of Kidney Diseases written by K. Nitta and published by Karger Medical and Scientific Publishers. This book was released on 2018-05-07 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chronic kidney disease (CKD) is a global health burden with associated high economic costs to the health system. Main factors are the increasing number of patients with diabetes and hypertension and the aging of the population. CKD has been associated with increased risks of cardiovascular morbidity, premature mortality, and/or decreased quality of life. In this new volume, renowned Japanese scientists present their recent research results. Papers cover various aspects of kidney diseases such as cystic kidney diseases, treatment of lupus nephritis, renal anemia and iron metabolism, cell sheet engineering, frailty and outcomes of dialysis patients, and the socioeconomics of rituximab in nephrotic syndrome. Due to the wide range of topics presented, this book will be of interest to readers from various clinical and research settings connected with the care of CKD patients.