Download or read book Abnormal Nutrition in the Human Articular Cartilages written by Peter Redfern and published by . This book was released on 1850 with total page 82 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Anormal Nutrition in the Human Articular Cartilages with experimental researches on the lower animals written by Peter REDFERN and published by . This book was released on 1850 with total page 96 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Effects of a High fat Diet on Cartilage in the Femoro tibial Joint of Young Adult Rats written by Samuel sinclair Hayson and published by . This book was released on 2016 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: Obesity is a major risk factor in the development of many diseases, including those of the musculoskeletal system such as osteoarthritis (OA). Recent studies of the knee joint of severally obese children detected articular cartilage (AC) lesions, the significance of which, in long-term risks of OA in adults, is not known. Using a rat model, this thesis project aimed to test the hypothesis that a high-fat (HF) diet would result in abnormalities in the femoro-tibial joint (FTJ) cartilages. It also examined the potential effect of exercise in preventing the effects of diet-induced obesity on FTJ cartilage. Upon weaning, 40 male Sprague-Dawley rats were fed a Chow (18% kal fat) or HF (45% kcal fat) diet. At 63 days half of each group was allocated to either spontaneous cage activity (SED) or to free access to an exercise wheel (EX), resulting in 4 groups (Chow-SED, HF-SED, Chow-EX, HF-EX). Body composition was assessed using dual-energy X-ray absorptiometry (DEXA), and fasting plasma leptin and insulin concentrations using ELISA. Femoro-tibial joint samples were processed for histological examination, stained with toluidine blue, and assessed for cartilage abnormalities. Epiphyseal growth cartilage (EGC) was graded using a modified cartilage grading protocol. Type X collagen within the EGC was assessed using immunohistochemistry. Pearson’s correlation was conducted between body composition, leptin concentration and the presence of cartilage abnormalities. Body mass, percentage body fat, and fasting plasma leptin and insulin concentrations were higher in HF than Chow-fed animals, and lower in exercised than in nonexercised animals. There was no evidence that HF diet or exercise was associated with hyaline articular cartilage (HAC) abnormality. Epiphyseal growth cartilage abnormalities consistent with the disease osteochondrosis (OC) were observed. There were significantly greater numbers of osteochondritic lesions in HF-SED and HF-EX animals compared to Chow control groups. Type X collagen staining was also present within the abnormalities of the epiphyseal cartilage, consistent with a disruption in endochondral ossification. Body weight (p=0.006), percentage body fat (p=0.002) and fasting plasma leptin concentration (p=0.027) were significantly correlated with the presence of abnormalities in the epiphyseal growth cartilage. This is the first known study to observe abnormalities in the EGC of young adult rats exposed to a HF diet. Both the mechanism leading to the formation of osteochondral defects in the young rat, and features of a HF diet that appear to exacerbate formation of EGC abnormalities need to be established before translation and comparison to cartilage lesions in young people can be achieved.
Download or read book Transactions of the Pathological Society of London written by Pathological Society and published by . This book was released on 1869 with total page 582 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Transactions of the Pathological Society of London written by Pathological Society of London and published by . This book was released on 1869 with total page 580 pages. Available in PDF, EPUB and Kindle. Book excerpt: List of members in vol. 2-58.
Download or read book Transactions of the Royal Academy of Medicine in Ireland written by Academy of Medicine in Ireland and published by . This book was released on 1903 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Transactions of the Royal Academy of Medicine in Ireland written by Royal Academy of Medicine in Ireland and published by . This book was released on 1903 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Association medical journal written by Provincial Medical and Surgical Association and published by . This book was released on 1854 with total page 1218 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Nutrition and Rheumatic Disease written by Laura A. Coleman and published by Springer Science & Business Media. This book was released on 2008-03-11 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book, experts provide a comprehensive review of current knowledge regarding nutrition and dietary management for the complex set of rheumatic conditions. Within the disease-specific chapters, the authors present a historical perspective, a discussion of the major clinical features, current management and treatment, a review of the literature related to nutritional status and diet, and dietary recommendations, based on current scientific evidence. The field of rheumatic diseases includes a wide variety of pathologic processes. This book will greatly benefit physicians specializing in internal medicine, family practice, and rheumatology.
Download or read book Nutrition and Arthritis written by Margaret Rayman and published by John Wiley & Sons. This book was released on 2008-04-15 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: Arthritis affects millions of people throughout the world and while its treatment is usually medical or surgical, there exists an increasingly large body of evidence concerning the positive effects of nutrition on the condition. There are over two hundred forms of rheumatoid disease, with conditions varying in prevalence. In this important title the authors have focussed on osteoarthritis (OA) and rheumatoid arthritis (RA), the most common arthritic diseases with the largest body of dietary data. Including coverage of disease incidence and prevalence, pathology, aetiology and measures of disease assessment and dietary risk factors, Nutrition and Arthritis is a clear, concise and user-friendly book gathering the latest research to bring the reader state-of-the-art information on: Micronutrients (e.g. vitamins C, D and selenium), food supplements and their potential to ameliorate arthritis Polyunsaturated fatty acids, with particular attention paid to n-3 fatty acids Glucosamine and chondroitin The value of exclusion, vegetarian, vegan and other dietary approaches Nutritionists and dietitians, including those working in the health services, rheumatologists, orthopaedic surgeons, general practitioners, osteopaths and commercial organisations involved in the formulation of dietary supplements will find this book an important and practical reference source. Libraries in medical schools and universities and research establishments where nutrition, dietetics and food science are studied and taught will find it a valuable addition to their shelves.
Download or read book Studies in Microscopical Sciences written by Arthur Charles Cole and published by . This book was released on 1883 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Biology of Cartilage Cells written by R. A. Stockwell and published by CUP Archive. This book was released on 1979-09-13 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Principles of Human Physiology with their chief applications to pathology hygiene and forensic medicine Second edition written by William Benjamin CARPENTER and published by . This book was released on 1869 with total page 1076 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Studies in Microscopical Science written by and published by . This book was released on 1883 with total page 706 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Principles of human physiology written by William Benjamin Carpenter and published by . This book was released on 1876 with total page 1134 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Principles of Regenerative Medicine written by Anthony Atala and published by Academic Press. This book was released on 2010-12-16 with total page 1203 pages. Available in PDF, EPUB and Kindle. Book excerpt: Virtually any disease that results from malfunctioning, damaged, or failing tissues may be potentially cured through regenerative medicine therapies, by either regenerating the damaged tissues in vivo, or by growing the tissues and organs in vitro and implanting them into the patient. Principles of Regenerative Medicine discusses the latest advances in technology and medicine for replacing tissues and organs damaged by disease and of developing therapies for previously untreatable conditions, such as diabetes, heart disease, liver disease, and renal failure. - Key for all researchers and instituions in Stem Cell Biology, Bioengineering, and Developmental Biology - The first of its kind to offer an advanced understanding of the latest technologies in regenerative medicine - New discoveries from leading researchers on restoration of diseased tissues and organs
Download or read book The Journal of Anatomy and Physiology Normal and Pathological Human and Comparative written by and published by . This book was released on 1898 with total page 974 pages. Available in PDF, EPUB and Kindle. Book excerpt:
