Download or read book A Wandering Natural Products Chemist written by Kōji Nakanishi and published by . This book was released on 1991 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: Koji Nakanishi's free thinking and exuberant personality is illustrated in the style of his science and in the philosophies expressed in his stories. Nakanishi has contributed significantly to the development of various spectroscopic methods in organic chemistry, and has been a pioneer in the elucidation of structure and mechanisms in complex, unstable, and biologically active natural products. His famous talents as a magician are also described in this fascinating volume.
Download or read book Bioactive Natural Products written by Steven M. Colegate and published by CRC Press. This book was released on 2007-12-14 with total page 622 pages. Available in PDF, EPUB and Kindle. Book excerpt: Following the successful format of the original, this new edition presents applications of the most recent techniques for the detection, isolation, and structural determination of bioactive natural products. It features new case studies and illustrations that demonstrate applications of techniques covered in the book. Complementing as much as replacing the first edition, most of the contributors are new. The text includes updates on chemical extraction, and NMR-based structure determination, and new contributions on liquid chromatography linked with mass and NMR spectroscopy, dereplication approaches, assessment of source material for natural products and novel bioassay development.
Download or read book Chemistry of Plant Natural Products written by Sunil Kumar Talapatra and published by Springer. This book was released on 2015-03-05 with total page 1197 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aimed at advanced undergraduate and graduate students and researchers working with natural products, Professors Sunil and Bani Talapatra provide a highly accessible compilation describing all aspects of plant natural products. Beginning with a general introduction to set the context, the authors then go on to carefully detail nomenclature, occurrence, isolation, detection, structure elucidation (by both degradation and spectroscopic techniques) stereochemistry, conformation, synthesis, biosynthesis, biological activity and commercial applications of the most important natural products of plant origin. Each chapter also includes detailed references (with titles) and a list of recommended books for additional study making this outstanding treatise a useful resource for teachers of chemistry and researchers working in universities, research institutes and industry.
Download or read book A Wandering Natural Products Chemist written by Kōji Nakanishi and published by . This book was released on 1991-01-01 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Introduction to Natural Products Chemistry written by Rensheng Xu and published by CRC Press. This book was released on 2011-07-20 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: Natural products chemistry—the chemistry of metabolite products of plants, animals and microorganisms—is involved in the investigation of biological phenomena ranging from drug mechanisms to gametophytes and receptors and drug metabolism in the human body to protein and enzyme chemistry. Introduction to Natural Products Chemistry has collected the most important research results of natural product chemistry in China. It overviews the basic principles of isolation, structure, and characteristics of natural products and illustrates current research techniques of structure elucidation with real-life examples of wet chemistry and spectroscopic analyses (UV, IR, MS, and NMR, especially 2d-NMR, HMBC, and HMQC), bioactivity, biosynthesis, and chemical synthesis. Specifically, this book covers: Extraction and isolation of natural products Chemistry of fungal products Alkaloids, sesquiterpenoids, diterpenes, and saponins Amino acids and peptides Flavonoids, anthraquinones, coumarins, and lignans Marine natural products Structural modification of active principles from traditional Chinese medicine Chemical synthesis of natural products Although natural products chemistry has produced enormous results and made great contributions to human health, industry, and agriculture, only a fraction of natural resources have been rigorously studied. Chinese natural products are a gold mine for further exploration with modern technology and methods. This book represents the continuing collaboration between the fields of natural products chemistry, medicine, biology, and agriculture which will continue to discover and implement novel chemical products from natural sources.
Download or read book Fortschritte der Chemie organischer Naturstoffe Progress in the Chemistry of Organic Natural Products written by and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt: Contents: A.A. Leslie Gunatilaka: Triterpenoid Quinonemethides and Related Compounds (Celastroloids). - P. Walser-Volken and Ch. Tamm: The Spirostaphylotrichins and Related Microbial Metabolites. The volumes of this classic series, now referred to simply as "Zechmeister” after its founder, L. Zechmeister, have appeared under the Springer Imprint ever since the series’ inauguration in 1938. The volumes contain contributions on various topics related to the origin, distribution, chemistry, synthesis, biochemistry, function or use of various classes of naturally occurring substances ranging from small molecules to biopolymers. Each contribution is written by a recognized authority in his field and provides a comprehensive and up-to-date review of the topic in question. Addressed to biologists, technologists, and chemists alike, the series can be used by the expert as a source of information and literature citations and by the non-expert as a means of orientation in a rapidly developing discipline.
Download or read book Studies in Natural Products Chemistry written by Atta-ur Rahman and published by Elsevier. This book was released on 2023-09-13 with total page 546 pages. Available in PDF, EPUB and Kindle. Book excerpt: Studies in Natural Products Chemistry, Volume 78 covers the synthesis or testing and recording of the medicinal properties of natural products, providing cutting-edge accounts of the fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of bioactive natural products. Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate and then determine the structures and biological activity of natural products rapidly, thus opening up exciting opportunities in the field of new drug development to the pharmaceutical industry. - Focuses on the chemistry of bioactive natural products - Contains contributions by leading authorities in the field - Presents sources of new pharmacophores
Download or read book Studies in Natural Products Chemistry written by and published by Elsevier. This book was released on 2019-02-05 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: Studies in Natural Products Chemistry, Volume 62 discusses natural products in the plant and animal kingdom that offer a huge diversity of chemical structures resulting from biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to rapidly isolate and determine the structures and biological activity of natural products, thus opening up exciting opportunities in the field of new drug development to the pharmaceutical industry. This series covers the synthesis or testing and recording of the medicinal properties of natural products, providing cutting-edge accounts of the fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of bioactive natural products. - Focuses on the chemistry of bioactive natural products - Contains contributions by leading authorities in the field - Presents sources of new pharmacophores
Download or read book Dynamic Aspects Of Natural Products Chemistry written by Takeshi Ogura and published by CRC Press. This book was released on 1997-11-21 with total page 694 pages. Available in PDF, EPUB and Kindle. Book excerpt: Preface: Natural products chemistry has a long history, and could be regarded as having its roots in the use of many kinds of herbal mixtures as crude drugs in traditional medicine. Systems of traditional medicine have been practiced in China and Japan for thousands of years, and virtually all regions of the world have used natural materials to treat human disease. It was clear that many plants, herbs, etc. contain components with powerful biological activities. The dawn of modern natural products chemistry began with the isolation of the active component, morphine, from opium. Subsequently, various alkaloids were isolated from medicinal plants and employed clinically. The discovery and the development of penicillin as a microbial metabolite opened up the era of antibiotics, which have saved countless lives in the past half century or so. The isolation and synthesis of steroid hormones resulted in the development of new concepts in molecular stereochemistry and organic synthetic techniques, as did the discovery of bioactive lipids such as prostaglandins and leukatrienes, bioactive peptides such as enkephalins and endetherines, and oligosaccharides, including glycoproteins. Further, the discovery of plant hormones has led to great strides in plant biotechnology, including plant tissue cultures, and derivatives of insect hormones and pheromones are now used as pesticides. Thus, applications of natural products chemistry have become all-pervasive in modern society. Apart from the extensive practical applications of natural products and their derivatives, natural products chemistry has played a central role in the development of modern organic chemistry as a result of its focus on structural and synthetic studies of often highly complex and inaccessible molecules. Biosynthetic studies have also attracted much attention, aiming to answer the questions of why and how such a large number and variety of compounds are synthesised by organisms. Researchers in the field of biosynthesis first focused on elucidation of the pathways of secondary metabolism, and then on the mechanisms, of the enzymes catalyzing the biosynthetic reactions. This was an extremely difficult task, because rather large amounts of enzymes are required for the investigation of reaction mechanisms and the enzyme proteins are often unstable and not easy to purify. However, in recent years the development of molecular biology has made gene and protein engineering rather routine. Thus, studies of mechanistic enzymology can now be conducted with cloned and overexpressed enzyme proteins. It has been shown that the enzymes responsible for the biosynthesis of antibiotics in Streptomyces spp. are encoded in gene clusters. Further, cloning and functional analysis of the genes associated with flavonoid biosynthesis should soon cast light on the interesting question of why flavonoids are ubiquitously present in plant leaves. Life is maintained not only by large molecules such as proteins and nucleic acids, but also by many small molecules which have essential and diverse roles in the physiology of living organisms. Such compounds often have highly specific interactions with target receptors, but the mechanisms involved largely remain to be explored. Current methodology means that this task can be addressed, and this in turn should lead to a host of new applications for natural products and their derivatives. The key may be an interdisciplinary approach taking account of both biological function and molecular behaviour based on precise structure recognition. As we increasingly understand the mechanisms of molecular recognition that operate in nature, many possibilities should open up for artificial control or modification of biological functions, as well as new challenges for synthetic organic chemists. Our intention in this book is to focus on such dynamic aspects of natural products chemistry. By dealing in detail with representative topics to which the most modern techniques of research have been applied, we hope to emphasize the value of combining traditional approaches to natural products chemists with current biochemical and molecular-biological ideas. Each chapter provides sufficient background information and experimental detail to make the subject accessible to non-specialists. It is our hope that these examples of recent progress in key areas of natural products chemistry will stimulate work in related topics by illustrating the power of a modern interdisciplinary approach to the subject.
Download or read book Enough for One Lifetime written by Matthew E. Hermes and published by Chemical Heritage Foundation. This book was released on 1996 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a story of invention and chemistry and the ineluctable fate of the inventor of nylon. Wallace Carothers was hired by DuPont in 1928 to lead a program called basic research. Carothers brought a passion to his work, and wanted to synthesize large molecules that would challenge Emil Fischer's largest molecule of 4200 molecular weight. In a burst of creativity in the spring of 1930, Carothers gave us our first truly synthetic rubber and fiber. The rubber quickly became neoprene; the fiber, in time, led to nylon. Carothers took an infant science called polymer chemistry, defined it, and guided it toward its present maturity. He gave us condensation polymerization. Hermes tells Carothers' story - his sudden, dramatic research successes and his relentless slide into depression, alcohol, and suicide - through Carothers' revealing letters to his professional colleagues (Roger Adams, C. S. Marvel, John R. Johnson) and his family and college classmates. At the end, Carothers' habit was to hide himself from his co-workers and friends. Hermes' narrative searches for the shrouded heart of the inventor's story by using stories of F. Scott Fitzgerald and other contemporaries as parables from which Carothers' truth may be drawn.
Download or read book Chemical History written by Gerrylyn K Roberts and published by Royal Society of Chemistry. This book was released on 2007-10-31 with total page 261 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an historical overview of the recent developments in the history of diverse fields within chemistry. It follows on from Recent Developments in the History of Chemistry, a volume published in 1985. Covering chiefly the last 20 years, the primary aim of Chemical History: Reviews of the Recent Literature is to familiarise newcomers to the history of chemistry with some of the more important developments in the field. Starting with a general introduction and look at the early history of chemistry, subsequent chapters go on to investigate the traditional areas of chemistry (physical, organic, inorganic) alongside analytical chemistry, physical organic chemistry, medical chemistry and biochemistry, and instruments and apparatus. Topics such as industrial chemistry and chemistry in national contexts, whilst not featuring as separate chapters, are woven throughout the content. Each chapter is written by experts and is extensively referenced to the international chemical literature. Chemical History: Reviews of the Recent Literature is also ideal for chemists who wish to become familiar with historical aspects of their work. In addition, it will appeal to a wider audience interested in the history of chemistry, as it draws together historical materials that are widely scattered throughout the chemical literature.
Download or read book The Public Image of Chemistry written by Joachim Schummer and published by World Scientific. This book was released on 2007 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stem cells have the ability to differentiate into cells that are found throughout the body. This fundamental property of stem cells suggests that they can potentially be used to replace degenerative cells within the body, and regenerate the functional capacity of organ systems that have deteriorated because of disease or aging. This authoritative textbook provides an overview of the latest advances in the field of stem cell biology, spanning topics that include nuclear reprogramming, somatic cell cloning, and determinants of cell fate; embryonic stem cells for hematopoietic and pancreatic repair; adult stem cells for cardiovascular, neural, renal, and hepatic repair; and manufacturing of stem cells for clinical use.
Download or read book Biographies of Scientists written by Roger Smith and published by Scarecrow Press. This book was released on 1998 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides more than 500 sources of information on scientists for young and adult general readers and for scholars. These sources explain scientists' accomplishments in the context of the personal and career developments that made those accomplishments possible
Download or read book The Carbon Age written by Eric Roston and published by Bloomsbury Publishing USA. This book was released on 2010-08-09 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: What do bubbles in a soft drink, a bullet-proof vest, a plastic chair, and our DNA have in common? Carbon. It is, and forever has been, the ubiquitous architect of life and civilization, forming the chemical backbone of every living creature. And yet, when we hear the word today, it is more often than not in a crisis situation: carbon dioxide emissions are destroying the ozone layer and warming the planet; the volatile Middle East explodes atop its stores of hydrocarbons; carbohydrates threaten obesity and diabetics. Carbon, thus, sustains us and threatens us in equal measure, Eric Roston illuminates this essential element in all its forms, cleverly recreating the intricate carbon cycle on the page by tracing its journey from the Big Bang to Earth and its extraordinary infiltration of this planet and, in time, influence on humankind and civilization. Evoking its ubiquity-more than 99% of all 31 million known substances contain carbon-Roston chronicles the ways we have used it, often to surprising, and sometimes to catastrophic, effect: having sped up the carbon cycle in the last two centuries, we are now attempting to wrestle Earth's geochemical cycle back from the brink. Blending the latest science with original reporting, Roston makes us aware, as never before, of the seminal impact carbon has, and has had, on our lives.
Download or read book Comprehensive Natural Products II written by and published by Elsevier. This book was released on 2010-03-05 with total page 7944 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work presents a definitive interpretation of the current status of and future trends in natural products—a dynamic field at the intersection of chemistry and biology concerned with isolation, identification, structure elucidation, and chemical characteristics of naturally occurring compounds such as pheromones, carbohydrates, nucleic acids, and enzymes. With more than 1,800 color figures, Comprehensive Natural Products II features 100% new material and complements rather than replaces the original work (©1999). Reviews the accumulated efforts of chemical and biological research to understand living organisms and their distinctive effects on health and medicine Stimulates new ideas among the established natural products research community—which includes chemists, biochemists, biologists, botanists, and pharmacologists Informs and inspires students and newcomers to the field with accessible content in a range of delivery formats Includes 100% new content, with more than 6,000 figures (1/3 of these in color) and 40,000 references to the primary literature, for a thorough examination of the field Highlights new research and innovations concerning living organisms and their distinctive role in our understanding and improvement of human health, genomics, ecology/environment, and more Adds to the rich body of work that is the first edition, which will be available for the first time in a convenient online format giving researchers complete access to authoritative Natural Products content
Download or read book Biomolecular Electronics written by Nikolai Vsevolodov and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: The properties of materials depend on the nature of the macromolecules, small molecules and inorganic components and the interfaces and interactions between them. Polymer chemistry and physics, and inorganic phase structure and density are major factors that influence the performance of materials. In addition, molecular recognition, organic-inorganic interfaces and many other types of interactions among components are key issues in determining the properties of materials for a wide range of applications. Materials require ments are becoming more and more specialized to meet increasingly demand ing needs, from specific environmental stresses to high performance or biomedical applications such as matrices for controlled release tissue scaf folds. One approach to meet these performance criteria is to achieve better control over the tailoring of the components and their interactions that govern the material properties. This goal is driving a great deal of ongoing research in material science laboratories. In addition, control at the molecular level of interactions between these components is a key in many instances in order to reach this goal since traditional approaches used to glue, stitch or fasten parts together can no longer suffice at these new levels of manipulation to achieve higher performance. In many cases, molecular recognition and self-assembly must begin to drive these processes to achieve the levels of control desired. This same need for improved performance has driven Nature over millenia to attain higher and higher complexity.
Download or read book A Semiempirical Life written by Michael James Steuart Dewar and published by . This book was released on 1992 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is an autobiography of Michael Dewar, eminent developer of the semi-empirical method of theoretical/computational chemistry. The personality and charm of this bold, brilliant and frequently brash scientist is vividly demonstrated in his stories, ranging from his early discovery of the structure of colchicine by analysis of literature data to his application of theoretical chemistry to numerous questions of chemical structure and reactivity. Dewar describes his childhood in India, his studies in Oxford in the 1940's, and his subsequent Professorships in England and at the University of Chicago and the University of Texas.
