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Book Comprehensive Medicinal Chemistry III

Download or read book Comprehensive Medicinal Chemistry III written by and published by Elsevier. This book was released on 2017-07-19 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive Medicinal Chemistry III, Eight Volume Set provides a contemporary and forward-looking critical analysis and summary of recent developments, emerging trends, and recently identified new areas where medicinal chemistry is having an impact. The discipline of medicinal chemistry continues to evolve as it adapts to new opportunities and strives to solve new challenges. These include drug targeting, biomolecular therapeutics, development of chemical biology tools, data collection and analysis, in silico models as predictors for biological properties, identification and validation of new targets, approaches to quantify target engagement, new methods for synthesis of drug candidates such as green chemistry, development of novel scaffolds for drug discovery, and the role of regulatory agencies in drug discovery. Reviews the strategies, technologies, principles, and applications of modern medicinal chemistry Provides a global and current perspective of today's drug discovery process and discusses the major therapeutic classes and targets Includes a unique collection of case studies and personal assays reviewing the discovery and development of key drugs

Book A Textbook of Medicinal Chemistry III

Download or read book A Textbook of Medicinal Chemistry III written by A Rajendiran, Ajay Kumar Gupta and Anju Singh and published by Shashwat Publication. This book was released on 2023-11-03 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook of Medicinal Chemistry is useful for all the disciplines, course and programs related to medicinal chemistry that involves the integration of principles of medicinal chemistry with pharmacology, pharmaceutics, and therapeutics into a multi-semester course called pharmacodynamics, pharmacotherapeutics, or another similar name. But this book is more precise for students of pharmaceutical sciences, with special emphasis on syllabus prescribed by Pharmacy Council of India (PCI) for undergraduate students of all Indian Universities. The chapters of this textbook include a combination of principles of pharmacology and medicinal chemistry, necessary for understanding structure–activity relationships (SAR) and mechanisms of drug action (MOA), the book should be useful in supporting courses in medicinal chemistry and in complementing pharmacology courses. The authors of this textbook of Medicinal Chemistry III are pharmacy professionals, and are influenced by respective academic backgrounds, with the objective of continuing the tradition of a modern textbook for undergraduate students and also for graduate students who need a general review of medicinal chemistry. We believe that our collaboration on this textbook represents a blending of our perspectives that will provide new dimensions of appreciation and better understanding for students of pharmaceutical sciences. Finally in writing this multi-authored textbook we have tried to simplify with consistent style in the respective chapters.

Book Textbook of Medicinal Chemistry Vol II   E Book

Download or read book Textbook of Medicinal Chemistry Vol II E Book written by V Alagarsamy and published by Elsevier Health Sciences. This book was released on 2012-06-16 with total page 833 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dr Alagarsamy's Textbook of Medicinal Chemistry is a much-awaited masterpiece in its arena. Targeted mainly to B. Pharm. students, this book will also be useful for M. Pharm. as well as M. Sc. organic chemistry and pharmaceutical chemistry students. It aims at eliminating the inadequacies in teaching and learning of medicinal chemistry by providing enormous information on all the topics in medicinal chemistry of synthetic drugs. Salient Features Contains clear classification, synthetic schemes, mode of action, metabolism, assay, pharmacological uses with the dose and structure–activity relationship (SAR) of the following classes of drugs: Drugs acting on inflammation Drugs acting on respiratory system Drugs acting on digestive system Drugs acting on blood and blood-forming organs Drugs acting on endocrine system Contains a complete section on chemotherapy and the various classes of chemotherapeutic agents. Also includes recent topics like anti-HIV agents Contains brief introduction about the physiological and pathophysiological conditions of diseases and their treatment under each topic Provides well-illustrated synthetic schemes and alternative synthetic routes for majority of drugs that help in quick and enhanced understanding of the subject Covers the syllabi of majority of Indian universities

Book A Textbook of MEDICINAL CHEMISTRY     III

    Book Details:
  • Author : Dr. Nilima Shukla , Mr. Shyam Wamanrao Rangari , Dr Baljinder Singh Bajwa , Dr. D. Sudhahar , Dr. Mejo Joseph
  • Publisher : Shashwat Publication
  • Release : 2023-09-11
  • ISBN : 8119517431
  • Pages : 177 pages

Download or read book A Textbook of MEDICINAL CHEMISTRY III written by Dr. Nilima Shukla , Mr. Shyam Wamanrao Rangari , Dr Baljinder Singh Bajwa , Dr. D. Sudhahar , Dr. Mejo Joseph and published by Shashwat Publication. This book was released on 2023-09-11 with total page 177 pages. Available in PDF, EPUB and Kindle. Book excerpt: The formulation development process is built upon the foundation of the pharmaceutical product development process. During the development of the product, the formulation scientist is responsible for paying attention to several parameters connected to the material (API, Excipients, and so on), the formulation process, the parameters of the formulation process, dosage forms, and so on. In this book, a variety of formulation development-related topics, including those pertaining to dosage, are broken down in a way that is clear and easy to grasp. I am hoping that both the students and the teachers will have positive reactions to this book. We are open to hearing recommendations regarding any and all aspects of the profession. We take full responsibility for any deviations or errors that may have been overlooked, and we would be extremely appreciative if readers would bring them to our attention if they did occur.

Book A Textbook of MEDICINAL CHEMISTRY     III

Download or read book A Textbook of MEDICINAL CHEMISTRY III written by Dr. P. Venkatesh, Dr. D. Hepcy Kalarani and published by Shashwat Publication. This book was released on 2024-09-14 with total page 275 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introducing the book "Medicinal Chemistry III" is something that fills me with an incredible amount of joy. The content of this book has been meticulously crafted to adhere to the curriculum for Bachelor of Pharmacy students that has been outlined by the Pharmacy Council of India. An effort has been made to investigate the topic using terminology that is as straightforward as possible in order to make it more simply digestible for pupils. The book has a number of illustrations, such as flowcharts and diagrams that make it simple for students to comprehend complex ideas. It is the author's honest desire that both students and academicians would take something helpful away from reading this book.

Book Medicinal Chemistry   III

Download or read book Medicinal Chemistry III written by K G Bothara and published by . This book was released on 2016-07-16 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt: 1 Narcotic analgesics 2 Anti inflammatory agents 3 Autacoids 4 Drugs acting on respiratory tract 5 Drugs acting on gastrointestinal tract Index

Book The Practice of Medicinal Chemistry

Download or read book The Practice of Medicinal Chemistry written by Camille Georges Wermuth and published by Elsevier. This book was released on 2015-07-01 with total page 903 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Practice of Medicinal Chemistry, Fourth Edition provides a practical and comprehensive overview of the daily issues facing pharmaceutical researchers and chemists. In addition to its thorough treatment of basic medicinal chemistry principles, this updated edition has been revised to provide new and expanded coverage of the latest technologies and approaches in drug discovery.With topics like high content screening, scoring, docking, binding free energy calculations, polypharmacology, QSAR, chemical collections and databases, and much more, this book is the go-to reference for all academic and pharmaceutical researchers who need a complete understanding of medicinal chemistry and its application to drug discovery and development. - Includes updated and expanded material on systems biology, chemogenomics, computer-aided drug design, and other important recent advances in the field - Incorporates extensive color figures, case studies, and practical examples to help users gain a further understanding of key concepts - Provides high-quality content in a comprehensive manner, including contributions from international chapter authors to illustrate the global nature of medicinal chemistry and drug development research - An image bank is available for instructors at www.textbooks.elsevier.com

Book A Textbook of MEDICINAL CHEMISTRY     III  BP601T

    Book Details:
  • Author : Dr. Gopi Reddy Alugubelli, Mr. Sushant Kumar Sharma, Dr. Susmita Basak, Ms. Priti. R. Shirsath, Dr. Arti Gupta
  • Publisher : Shashwat Publication
  • Release : 2024-08-06
  • ISBN : 9360874000
  • Pages : 223 pages

Download or read book A Textbook of MEDICINAL CHEMISTRY III BP601T written by Dr. Gopi Reddy Alugubelli, Mr. Sushant Kumar Sharma, Dr. Susmita Basak, Ms. Priti. R. Shirsath, Dr. Arti Gupta and published by Shashwat Publication. This book was released on 2024-08-06 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt: The introduction of the book "Medicinal Chemistry III" makes me incredibly happy. This book's content has been painstakingly created to conform to the Pharmacy Council of India's prescribed curriculum for students pursuing a bachelor's degree in pharmacy. To make the subject easier for students to understand, an attempt has been made to research it using as simple a vocabulary as possible. Many images throughout the book, including flowcharts and diagrams, help students understand difficult concepts. The genuine hope of the author is that readers of this book, academicians and students alike, will find something of value. The pharmaceutical product development process serves as the cornerstone for the formulation development process. The formulation scientist bears the responsibility of monitoring various material parameters (such as API and excipients), formulation process parameters, dosage forms, and other related aspects during the product development process. This book provides straightforward and understandable explanations of a wide range of formulation development-related subjects, including dose. I'm hopeful that this book will be well received by both teachers and students. We are willing to consider suggestions about any and all facets of the industry. Any faults or deviations that may have gone unnoticed are entirely our fault, and we would be very grateful if readers could point them out to us if they did.

Book Basic Concepts in Medicinal Chemistry

Download or read book Basic Concepts in Medicinal Chemistry written by Marc Harrold and published by ASHP. This book was released on 2013-01-18 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medicinal chemistry is a complex topic. Written in an easy to follow and conversational style, Basic Concepts in Medicinal Chemistry focuses on the fundamental concepts that govern the discipline of medicinal chemistry as well as how and why these concepts are essential to therapeutic decisions. The book emphasizes functional group analysis and the basics of drug structure evaluation. In a systematic fashion, learn how to identify and evaluate the functional groups that comprise the structure of a drug molecule and their influences on solubility, absorption, acid/base character, binding interactions, and stereochemical orientation. Relevant Phase I and Phase II metabolic transformations are also discussed for each functional group. Key features include: • Discussions on the roles and characteristics of organic functional groups, including the identification of acidic and basic functional groups. • How to solve problems involving pH, pKa, and ionization; salts and solubility; drug binding interactions; stereochemistry; and drug metabolism. • Numerous examples and expanded discussions for complex concepts. • Therapeutic examples that link the importance of medicinal chemistry to pharmacy and healthcare practice. • An overview of structure activity relationships (SARs) and concepts that govern drug design. • Review questions and practice problems at the end of each chapter that allow readers to test their understanding, with the answers provided in an appendix. Whether you are just starting your education toward a career in a healthcare field or need to brush up on your organic chemistry concepts, this book is here to help you navigate medicinal chemistry. About the Authors Marc W. Harrold, BS, Pharm, PhD, is Professor of Medicinal Chemistry at the Mylan School of Pharmacy, Duquesne University, Pittsburgh, PA. Professor Harrold is the 2011 winner of the Omicron Delta Kappa "Teacher of the Year" award at Duquesne University. He is also the two-time winner of the "TOPS" (Teacher of the Pharmacy School) award at the Mylan School of Pharmacy. Robin M. Zavod, PhD, is Associate Professor for Pharmaceutical Sciences at the Chicago College of Pharmacy, Midwestern University, Downers Grove, IL, where she was awarded the 2012 Outstanding Faculty of the Year award. Professor Zavod also serves on the adjunct faculty for Elmhurst College and the Illinois Institute of Technology. She currently serves as Editor-in-Chief of the journal Currents in Pharmacy Teaching and Learning.

Book MEDICINAL CHEMISTRY     III  A TEXTBOOK According to PCI syllabus

Download or read book MEDICINAL CHEMISTRY III A TEXTBOOK According to PCI syllabus written by Dr. Sushama Rawat , Prof. Kakasaheb. J. Kore , Dr. K. Blessi Priyanka , Mr. S. G. Raman, Dr. Vipul Trikambhai Prajapati and published by Shashwat Publication. This book was released on 2024-05-28 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introducing the book "Medicinal Chemistry III" is something that fills me with an incredible amount of joy. The content of this book has been meticulously crafted to adhere to the curriculum for Bachelor of Pharmacy students that has been outlined by the Pharmacy Council of India. The formulation development process is built upon the foundation of the pharmaceutical product development process. During the development of the product, the formulation scientist is responsible for paying attention to several parameters connected to the material (API, Excipients, and so on), the formulation process, the parameters of the formulation process, dosage forms, and so on. In this book, medicinal chemistry topics, including those pertaining to dosage, are broken down in a way that is clear and easy to grasp.

Book Textbook of Organic Medicinal and Pharmaceutical Chemistry

Download or read book Textbook of Organic Medicinal and Pharmaceutical Chemistry written by Charles Owens Wilson and published by Lippincott Williams & Wilkins. This book was released on 1977 with total page 1150 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Medicinal Chemistry

    Book Details:
  • Author : Thomas Nogrady
  • Publisher : Oxford University Press
  • Release : 2005-08-11
  • ISBN : 0190282967
  • Pages : 664 pages

Download or read book Medicinal Chemistry written by Thomas Nogrady and published by Oxford University Press. This book was released on 2005-08-11 with total page 664 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fully updated and rewritten by a basic scientist who is also a practicing physician, the third edition of this popular textbook remains comprehensive, authoritative and readable. Taking a receptor-based, target-centered approach, it presents the concepts central to the study of drug action in a logical, mechanistic way grounded on molecular and principles. Students of pharmacy, chemistry and pharmacology, as well as researchers interested in a better understanding of drug design, will find this book an invaluable resource. Starting with an overview of basic principles, Medicinal Chemistry examines the properties of drug molecules, the characteristics of drug receptors, and the nature of drug-receptor interactions. Then it systematically examines the various families of receptors involved in human disease and drug design. The first three classes of receptors are related to endogenous molecules: neurotransmitters, hormones and immunomodulators. Next, receptors associated with cellular organelles (mitochondria, cell nucleus), endogenous macromolecules (membrane proteins, cytoplasmic enzymes) and pathogens (viruses, bacteria) are examined. Through this evaluation of receptors, all the main types of human disease and all major categories of drugs are considered. There have been many changes in the third edition, including a new chapter on the immune system. Because of their increasingly prominent role in drug discovery, molecular modeling techniques, high throughput screening, neuropharmacology and genetics/genomics are given much more attention. The chapter on hormonal therapies has been thoroughly updated and re-organized. Emerging enzyme targets in drug design (e.g. kinases, caspases) are discussed, and recent information on voltage-gated and ligand-gated ion channels has been incorporated. The sections on antihypertensive, antiviral, antibacterial, anti-inflammatory, antiarrhythmic, and anticancer drugs, as well as treatments for hyperlipidemia and peptic ulcer, have been substantially expanded. One new feature will enhance the book's appeal to all readers: clinical-molecular interface sections that facilitate understanding of the treatment of human disease at a molecular level.

Book Textbook of Medicinal Chemistry

    Book Details:
  • Author : V. ALAGARSAMY
  • Publisher : CBS Publishers & Distributors Pvt Limited, India
  • Release : 2018-03-30
  • ISBN : 9789385915505
  • Pages : pages

Download or read book Textbook of Medicinal Chemistry written by V. ALAGARSAMY and published by CBS Publishers & Distributors Pvt Limited, India. This book was released on 2018-03-30 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This popular textbook for pharmacy students provides all the information they need to know about medicinal chemistry. The third edition features new layout and design in an attractive two-colour presentation. It contains clear classifications, synthetic schemes, modes of action, metabolism, assay, pharmacological uses with the dose and structure activity relationship (SAR) of the drugs for the various body systems. - Contains a complete section on drug design, describing the new drug development. - Includes an introduction to the physiological and pathophysiological conditions of diseases and their treatment. - Provides well-illustrated synthetic schemes and alternative synthetic routes for the majority of drugs. - Additional physico-chemical parameters have been explained.

Book Platform Technologies in Drug Discovery and Validation

Download or read book Platform Technologies in Drug Discovery and Validation written by and published by Academic Press. This book was released on 2017-11-21 with total page 692 pages. Available in PDF, EPUB and Kindle. Book excerpt: Platform Technologies in Drug Discovery and Validation, Volume 50, the latest release in the Annual Reports in Medicinal Chemistry series, provides timely and critical reviews of important topics in medicinal chemistry, with an emphasis on emerging topics in the biological sciences. Topics covered in this new volume include DELT, Oligos: ASO, siRNA, CRISPR, Micro-fluidic chemistry, High throughput screening, Kinase-centric computational drug development, Virtual Screening, Phenotypic screening, PROTACS, Chemical Biology, Fragment-based lead generation, Antibody-Drug Conjugates, Antibody-recruiting small molecules, Deuteration, and Peptides. - Unique for its treatment of platform technologies for medicinal chemistry and target validation - Provides a single, rich volume that summaries a broad spectrum of expertise relevant to the field - Presents state-of-the-art summaries of platform technologies

Book Natural Products in Medicinal Chemistry

Download or read book Natural Products in Medicinal Chemistry written by Stephen Hanessian and published by John Wiley & Sons. This book was released on 2013-12-18 with total page 652 pages. Available in PDF, EPUB and Kindle. Book excerpt: The inspiration provided by biologically active natural products to conceive of hybrids, congeners, analogs and unnatural variants is discussed by experts in the field in 16 highly informative chapters. Using well-documented studies over the past decade, this timely monograph demonstrates the current importance and future potential of natural products as starting points for the development of new drugs with improved properties over their progenitors. The examples are chosen so as to represent a wide range of natural products with therapeutic relevance among others, as anticancer agents, antimicrobials, antifungals, antisense nucleosides, antidiabetics, and analgesics. From the content: * Part I: Natural Products as Sources of Potential Drugs and Systematic Compound Collections * Part II: From Marketed Drugs to Designed Analogs and Clinical Candidates * Part III: Natural Products as an Incentive for Enabling Technologies * Part IV: Natural Products as Pharmacological Tools * Part V: Nature: The Provider, the Enticer, and the Healer

Book TEXTBOOK OF MEDICINAL CHEMISTRY II  BP501T   Theory

    Book Details:
  • Author : Dr. Gurinderdeep Singh, Mr. S. G. Raman , Professor Srinivasa Rao Atla , Dr. Ashish Ashok Gawai , Dr. K. Vijay Kishore
  • Publisher : Shashwat Publication
  • Release : 2024-07-11
  • ISBN : 9360874450
  • Pages : 256 pages

Download or read book TEXTBOOK OF MEDICINAL CHEMISTRY II BP501T Theory written by Dr. Gurinderdeep Singh, Mr. S. G. Raman , Professor Srinivasa Rao Atla , Dr. Ashish Ashok Gawai , Dr. K. Vijay Kishore and published by Shashwat Publication. This book was released on 2024-07-11 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introducing the book "Medicinal Chemistry - II" is something that fills me with an incredible amount of joy. The content of this book has been meticulously crafted to adhere to the curriculum for Bachelor of Pharmacy students that has been outlined by the Pharmacy Council of India. An effort has been made to investigate the topic using terminology that is as straightforward as possible in order to make it more simply digestible for pupils. The book has a number of illustrations, such as flowcharts and diagrams that make it simple for students to comprehend complex ideas. It is the author's honest desire that both students and academicians would take something helpful away from reading this book.

Book Advances in Medicinal Chemistry

Download or read book Advances in Medicinal Chemistry written by B.E. Maryanoff and published by Elsevier. This book was released on 1999-04-01 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume 4 of Advances in Medicinal Chemistry is comprised of six chapters on a wide range of topics in medicinal chemistry, including molecular modeling, structure-based drug design, organic synthesis, peptide conformational analysis, biological assessment, structure-activity correlation, and lead optimization. Chapter 1 presents an account about amino acid-based peptide mimetics corresponding to b-turn, loop, helical motifs in proteins as a probe of ligand-receptor and ligand-enzyme molecular interactions. Chapter 2 addresses new facets of the medicinal chemistry of the important anticancer drug Taxol® (paclitaxel). Chapter 3 relates an account of the search for new drugs for the treatment of malaria based on the natural product artemisinin. Chapter 4 applies computational chemistry to the evaluation of compound libraries for biological testing. Chapter 5 describes the construction of a 3-dimensional molecular model of the human thrombin receptor, the first protease-activated G-protein coupled receptor (PAR-1), as a means to explore the intermolecular contacts involved in agonist peptide recognition. Finally, Chapter 6 describes the research conducted at Merck on inhibitors of farnesyl transferase as a potential treatment for human cancers.