Download or read book A Study of the Application of Adaptive Optics AO in Optical Coherence Tomography OCT and Confocal Microscopy for the Purpose of High Resolution Imaging written by Christopher Costa and published by . This book was released on 2016 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book High Resolution Imaging in Microscopy and Ophthalmology written by Josef F. Bille and published by Springer. This book was released on 2019-08-13 with total page 407 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book provides a comprehensive overview of the application of the newest laser and microscope/ophthalmoscope technology in the field of high resolution imaging in microscopy and ophthalmology. Starting by describing High-Resolution 3D Light Microscopy with STED and RESOLFT, the book goes on to cover retinal and anterior segment imaging and image-guided treatment and also discusses the development of adaptive optics in vision science and ophthalmology. Using an interdisciplinary approach, the reader will learn about the latest developments and most up to date technology in the field and how these translate to a medical setting. High Resolution Imaging in Microscopy and Ophthalmology – New Frontiers in Biomedical Optics has been written by leading experts in the field and offers insights on engineering, biology, and medicine, thus being a valuable addition for scientists, engineers, and clinicians with technical and medical interest who would like to understand the equipment, the applications and the medical/biological background. Lastly, this book is dedicated to the memory of Dr. Gerhard Zinser, co-founder of Heidelberg Engineering GmbH, a scientist, a husband, a brother, a colleague, and a friend.
Download or read book Handbook of Adaptive Optics written by Enrique Josua Fernandez and published by CRC Press. This book was released on 2024-09-02 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: Adaptive Optics (AO) is a technique allowing the manipulation of the wavefront of the light benefitting multiple fields like Microscopy, Optical Coherence Tomography, Visual Testing, Optical Communications, and Astronomical Optics, just to mention some examples. Handbook of Adaptive Optics contains a complete picture of the technique from the foundations to the most promising applications of AO in a variety of fields. Within this book, the reader will find different sections, including: a complete and rigorous introduction to the foundation of the technique from a general perspective, providing the reader a solid basis in AO with particular emphasis on wavefront sensing methods and aberration correctors. It also discusses state-of-the-art applications and industrial usages with their particular constraints and methods to incorporate AO, like in some imaging techniques of importance for Biomedical Optics, in Astronomy and for Visual Optics. Furthermore, it explores discussions of the future of AO together with some of the most exciting emerging applications, including quantum technologies, scattering correction, space telescopes, and discrete AO, among others. This timely handbook will be an important companion to those starting in the field, but it will also serve as a comprehensive resource for researchers and experts who are already working with AO.
Download or read book Optical Coherence Tomography written by Wolfgang Drexler and published by Springer Science & Business Media. This book was released on 2008-12-10 with total page 1346 pages. Available in PDF, EPUB and Kindle. Book excerpt: Optical coherence tomography (OCT) is the optical analog of ultrasound imaging and is emerging as a powerful imaging technique that enables non-invasive, in vivo, high resolution, cross-sectional imaging in biological tissue. This book introduces OCT technology and applications not only from an optical and technological viewpoint, but also from biomedical and clinical perspectives. The chapters are written by leading research groups, in a style comprehensible to a broad audience.
Download or read book The Development and Clinical Application of Innovative Optical Ophthalmic Imaging Techniques written by Peng Xiao and published by Frontiers Media SA. This book was released on 2022-12-06 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Light Reflex on Retinal Arteries and Veins written by Olaf Brinchmann-Hansen and published by . This book was released on 1986 with total page 64 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Selected Topics in Optical Coherence Tomography written by Gangjun Liu and published by BoD – Books on Demand. This book was released on 2012-02-08 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book includes different exciting topics in the OCT fields, written by experts from all over the world. Technological developments, as well as clinical and industrial applications are covered. Some interesting topics like the ultrahigh resolution OCT, the functional extension of OCT and the full field OCT are reviewed, and the applications of OCT in ophthalmology, cardiology and dentistry are also addressed. I believe that a broad range of readers, such as students, researchers and physicians will benefit from this book.
Download or read book Characterization of an AO OCT System written by and published by . This book was released on 2007 with total page 4 pages. Available in PDF, EPUB and Kindle. Book excerpt: Adaptive optics (AO) and optical coherence tomography (OCT) are powerful imaging modalities that, when combined, can provide high-volumetric-resolution, images of the retina. The AO-OCT system at UC Davis has been under development for 2 years and has demonstrated the utility of this technology for microscopic, volumetric, in vivo retinal imaging [1]. The current system uses an AOptix bimorph deformable mirror (DM) for low-order, high-stroke correction [2] and a 140-actuator Boston Micromachines DM for high-order correction [3]. We are beginning to investigate the potential for increasing the image contrast in this system using higher-order wavefront correction. The first step in this analysis is to quantify the residual wavefront error (WFE) in the current system. Developing an error budget is a common tool for improved performance and system design in astronomical AO systems [4, 5]. The process for vision science systems is also discussed in several texts e.g. [6], but results from this type of analysis have rarely been included in journal articles on AO for vision science. Careful characterization of the AO system will lead to improved performance and inform the design of a future high-contrast system. In general, an AO system error budget must include an analysis of three categories of residual WFE: errors in measuring the phase, errors caused by limitations of the DM(s), and errors introduced by temporal variation. Understanding the mechanisms and relative size of these errors is critical to improving system performance. In this paper we discuss the techniques for characterizing these error sources in the AO-OCT system. It is useful to first calculate an error budget for the simpler case using a model eye, and then add the additional errors introduced for the case of a human subject. Measurement error includes calibration error, wavefront sensor (WFS) CCD noise, and sampling errors. Calibration errors must be measured by an external system. Typically this error is inferred from measurements of the point spread function (PSF). It can also be estimated by measuring known wavefront errors and comparing to the WFS measurement. Both methods will be used in the AO-OCT system. In this particular system measurement error introduced by the WFS can be caused by low light levels, poor camera sensitivity at the operating wavelength and noise introduced by heat in the uncooled CCD. Also, the gaussian beam profile of the system causes centroids near the edges of the pupil to be dimmer, and thus noisier. The easiest way to estimate measurement error is to compare successive wavefront measurements when the system is stable. This techniques will include vibrations and other systematic errors. Alternatively the measurement error can be estimated from measured signal to noise. This is more complicated but will decouple measurement errors from stability measurements. Ultimately, even if the phase is measured perfectly, performance will still be limited by the fitting error [7]. This error is inversely proportional to the number of actuators of the DM. Basically wavefront errors with spatial frequencies greater than half the number of actuators across the aperture cannot be corrected. For DMs with modal influence functions (like the AOptix Bimorph in the AO-OCT system), this translates to the number of modes which can be corrected. The AO-OCT system over-samples the wavefront, so to some extent, we can measure these out-of-band errors directly. In addition to fitting error, the DM will introduce errors based on the ability of each individual actuator to go to the position demanded by the control system. Generally this voltage step size is limited by the resolution of the drive electronics and can be calculated analytically.
Download or read book Adaptive Optics for Biological Imaging written by Joel A Kubby and published by CRC Press. This book was released on 2013-04-26 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: Adaptive Optics for Biological Imaging brings together groundbreaking research on the use of adaptive optics for biological imaging. The book builds on prior work in astronomy and vision science. Featuring contributions by leaders in this emerging field, it takes an interdisciplinary approach that makes the subject accessible to nonspecialists who want to use adaptive optics techniques in their own work in biology and bioengineering. Organized into three parts, the book covers principles, methods, and applications of adaptive optics for biological imaging, providing the reader with the following benefits: Gives a general overview of applied optics, including definitions and vocabulary, to lay a foundation for clearer communication across disciplines Explains what kinds of optical aberrations arise in imaging through various biological tissues, and what technology can be used to correct for these aberrations Explores research done with a variety of biological samples and imaging instruments, including wide-field, confocal, and two-photon microscopes Discusses both indirect wavefront sensing, which uses an iterative approach, and direct wavefront sensing, which uses a parallel approach Since the sample is an integral part of the optical system in biological imaging, the field will benefit from participation by biologists and biomedical researchers with expertise in applied optics. This book helps lower the barriers to entry for these researchers. It also guides readers in selecting the approach that works best for their own applications.
Download or read book Adaptive Optics for Vision Science written by Jason Porter and published by John Wiley & Sons. This book was released on 2006-06-12 with total page 624 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leading experts present the latest technology and applications in adaptive optics for vision science Featuring contributions from the foremost researchers in the field, Adaptive Optics for Vision Science is the first book devoted entirely to providing the fundamentals of adaptive optics along with its practical applications in vision science. The material for this book stems from collaborations fostered by the Center for Adaptive Optics, a consortium of more than thirty universities, government laboratories, and corporations. Although the book is written primarily for researchers in vision science and ophthalmology, the field of adaptive optics has strong roots in astronomy. Researchers in both fields share this technology and, for this reason, the book includes chapters by both astronomers and vision scientists. Following the introduction, chapters are divided into the following sections: * Wavefront Measurement and Correction * Retinal Imaging Applications * Vision Correction Applications * Design Examples Readers will discover the remarkable proliferation of new applications of wavefront-related technologies developed for the human eye. For example, the book explores how wavefront sensors offer the promise of a new generation of vision correction methods that can deal with higher order aberrations beyond defocus and astigmatism, and how adaptive optics can produce images of the living retina with unprecedented resolution. An appendix includes the Optical Society of America's Standards for Reporting Optical Aberrations. A glossary of terms and a symbol table are also included. Adaptive Optics for Vision Science arms engineers, scientists, clinicians, and students with the basic concepts, engineering tools, and techniques needed to master adaptive optics applications in vision science and ophthalmology. Moreover, readers will discover the latest thinking and findings from the leading innovators in the field.
Download or read book Optical Coherence Tomography written by Mark E. Brezinski and published by Elsevier. This book was released on 2006-08-25 with total page 645 pages. Available in PDF, EPUB and Kindle. Book excerpt: Optical Coherence Tomography gives a broad treatment of the subject which will include 1)the optics, science, and physics needed to understand the technology 2) a description of applications with a critical look at how the technology will successfully address actual clinical need, and 3) a discussion of delivery of OCT to the patient, FDA approval and comparisons with available competing technologies. The required mathematical rigor will be present where needed but be presented in such a way that it will not prevent non-scientists and non-engineers from gaining a basic understanding of OCT and the applications as well as the issues of bringing the technology to the market. - Optical Coherence Tomography is a new medical high-resolution imaging technology which offers distinct advantages over current medical imaging technologies and is attracting a large number of researchers. - Provides non-scientists and non-engineers basic understanding of Optical Coherence Tomography applications and issues.
Download or read book Handbook of Visual Optics Volume Two written by Pablo Artal and published by CRC Press. This book was released on 2017-02-24 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Visual Optics offers an authoritative overview of encyclopedic knowledge in the field of physiological optics. It builds from fundamental concepts to the science and technology of instruments and practical procedures of vision correction, integrating expert knowledge from physics, medicine, biology, psychology, and engineering. The chapters comprehensively cover all aspects of modern study and practice, from optical principles and optics of the eye and retina to novel ophthalmic tools for imaging and visual testing, devices and techniques for visual correction, and the relationship between ocular optics and visual perception.
Download or read book Adaptive Optics Optical Coherence Tomography for in Vivo Retinal Imaging written by Yifan Jian and published by . This book was released on 2014 with total page 96 pages. Available in PDF, EPUB and Kindle. Book excerpt: Optical coherence tomography (OCT) is a non-invasive micrometer-resolution volumetric imaging modality that has been employed in diverse applications. In this thesis, we first describe a GPU accelerated program to perform FDOCT data processing and real time 3D volumetric rendering. The real time visualization of volumetric images provided by the GPU acceleration was essential to the rest of the work described in this thesis. Small animal models of retinal diseases serve as a vital component in vision research, and non-invasive in vivo imaging is becoming an increasingly important tool in the field. We describe the first adaptive optics optical coherence tomography (AOOCT) imaging system for high resolution mouse retinal imaging. Images of mouse retina acquired with AOOCT showed significant improvement in the brightness and contrast of capillaries and nerve fiber bundles. However, the accuracy of wavefront sensing limited the performance of AOOCT. A novel wavefront sensorless adaptive optics (WSAO) OCT system was developed to overcome the issues associated with conventional wavefront sensing. Combination of WSAO with OCT allows coherence gated, depth resolved aberration correction. Images of both pigmented and albino mouse retinas acquired using WSAO OCT system demonstrated superior image quality. The real time high resolution WSAO OCT was leveraged for a time course study of laser exposure in the retina.
Download or read book Optical Coherence Tomography and Its Non medical Applications written by Michael Wang and published by BoD – Books on Demand. This book was released on 2020-05-27 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: Optical coherence tomography (OCT) is a promising non-invasive non-contact 3D imaging technique that can be used to evaluate and inspect material surfaces, multilayer polymer films, fiber coils, and coatings. OCT can be used for the examination of cultural heritage objects and 3D imaging of microstructures. With subsurface 3D fingerprint imaging capability, OCT could be a valuable tool for enhancing security in biometric applications. OCT can also be used for the evaluation of fastener flushness for improving aerodynamic performance of high-speed aircraft. More and more OCT non-medical applications are emerging. In this book, we present some recent advancements in OCT technology and non-medical applications.
Download or read book Development and Application of Optical Coherence Tomography OCT written by Michael Pircher and published by MDPI. This book was released on 2018-03-23 with total page 213 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a printed edition of the Special Issue "Development and Application of Optical Coherence Tomography (OCT)" that was published in Applied Sciences
Download or read book Adaptive Optics for Industry and Medicine written by Christopher Dainty and published by Imperial College Press. This book was released on 2008 with total page 519 pages. Available in PDF, EPUB and Kindle. Book excerpt: This proceedings volume presents the very latest developments in non-astronomical adaptive optics. This international workshop, the sixth in a biennial series, was the largest ever held and boasted significant involvement by industry. Adaptive optics is on the verge of being used in many products; indeed, at this meeting, the use of adaptive optics in DVD players was disclosed for the first time. Sample Chapter(s). Liquid Crystal Lenses For Correction Of Presbyopia (586 KB). Contents: Wavefront Correctors and Control: Liquid Crystal Lenses for Correction of Presbyopia (G Li & N Peyghambarian); Woofer-Tweeter Adaptive Optics (T Farrell & C Dainty); Wavefront Sensors: A Fundamental Limit for Wavefront Sensing (C Paterson); Direct Diffractive Image Simulation (A P Maryasov et al.); Adaptive Optics in Vision Science: A Study of Field Aberrations in the Human Eye (A V Goncharov et al.); Characterization of an AO-OCT System (J W Evans et al.); Adaptive Optics in Optical Storage and Microscopy: Commercialization of the Adaptive Scanning Optical Microscope (ASOM) (B Potsaid et al.); Towards Four Dimensional Particle Tracking for Biological Applications (H I Campbell et al.); Adaptive Optics in Lasers: New Results in High Power Lasers Beam Correction (A Kudryashov et al.); Adaptive Optics Control of Solid-State Lasers (W Lubeigt et al.); Adaptive Optics in Communication and Atmospheric Compensation: Fourier Image Sharpness Sensor for Laser Communications (K N Walker & R K Tyson); Adaptive Optics System for a Small Telescope (G Vdovin et al.); and other papers. Readership: Industry- and university-level researchers in optics and laser physics.
