Download or read book A Segmented ring Ion Trap Storage Source reflectron time of flight Mass Spectrometer written by Qinchung Ji and published by . This book was released on 1996 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Use of an Ion Trap Storage reflectron Time of flight Mass Spectrometer as a Rapid and Sensitive Mass and Tandem Mass Detector for Capillary Separations written by Jingtao Wu and published by . This book was released on 1997 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Practical Aspects of Ion Trap Mass Spectrometry written by Raymond E. March and published by CRC Press. This book was released on 1995-09-18 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fundamentals of Ion Trap Mass Spectrometry presents an account of the development and theory of the quadrupole ion trap and its utilization as an ion storage device, a reactor for ion/molecular reactions, and a mass spectrometer. It also expands the appreciation of ion traps from that of a unique arrangement of electrodes of hyperbolic form (and having a pure quadrupole field) to a series of ion traps having fields with hexapole and octopole components and introduces the practical ion trapping device in which electrode spacing has been increased. The fundamentals of ion trap are covered in four chapters, beginning with the origin of the ion trap, its development and operating principles, and improvements in performance. The second part focuses on the environment within the ion trap -- the movement of ions within the trap -- and how this movement is modified by repeated collisions of the ions with buffer gas atoms of helium, and on the collisions of ions with molecules that lead to chemical change. The critical role of collisions in focusing the ion cloud for subsequent operations is emphasized. This important reference presents a coherent picture of the present status of research in the ion trapping field to facilitate the entree of potential ion trappers and provide a backdrop for ion trap research and development in the future.
Download or read book Dissertation Abstracts International written by and published by . This book was released on 1996 with total page 712 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Mass Spectrometry written by Jürgen H Gross and published by Springer Science & Business Media. This book was released on 2006-04-05 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mass Spectrometry is an ideal textbook for students and professionals as well as newcomers to the field. Starting from the very first principles of gas-phase ion chemistry and isotopic properties, the textbook takes the reader through the design of mass analyzers and ionization methods all the way to mass spectral interpretation and coupling techniques. Step-by-step, the reader learns how mass spectrometry works and what it can do. The book comprises a balanced mixture of practice-oriented information and theoretical background. It features a clear layout and a wealth of high-quality figures. Exercises and solutions are located on the Springer Global Web.
Download or read book Development of a Quadrupole Ion Trap written by Beni B. Dangi and published by . This book was released on 2011 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: Development of a tandem mass spectrometer, consisting of a quadrupole ion trap (QIT) and a time-of-flight, is described for ion mass resolution and photophysics. Ions are generated externally by electrospray ionization and trapped in the quadrupole ion trap before extraction to the time-of-flight section for mass analysis. The non-parallel fields in the hyperbolic ion trap, which serves as the first acceleration region in the time-of-flight mass spectrometer, are shown to degrade spatial focusing and mass resolution. A novel short-pulse ion extraction method is shown to be useful in diagnosis of the trapped ion cloud size, energy and dispersal time. New ion trap geometries are evaluated theoretically for improvement in mass resolution as well as ion photophysics with similar ion trapping behavior compared with the existing hyperbolic ion trap. Parameters affecting mass resolutions in linear and reflectron time-of-flight modes are identified and possible improvements are discussed. An ion trap consisting of two endcaps and two ring flat electrodes is proposed and constructed on this basis. The newly optimized design is shown to yield the mass resolution of several thousand even at room temperature with moderate extraction field. Significant improvements in ion-laser interaction and photon collection are shown in the optimized design compared to the existing hyperbolic QIT. A molecular beam source is designed, fabricated and characterized for the application in ion-molecule collision experiments. Ionization methods, from solution to gas-phase, of small polycyclic aromatic hydrocarbons are developed and compared. A photo ionization source was designed and constructed to interface in the current mass spectrometer with fast switching capability with the current electrospray source.
Download or read book Practical Aspects of Ion Trap Mass Spectrometry written by Raymond E. March and published by CRC Press. This book was released on 1995-09-25 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: By delivering concentrated information in three different volumes, the editors of the Practical Aspects of Ion Trap Mass Spectrometry mini-series present in-depth reviews on mainstream developments in each active and popular area. Contributing authors provide concise reports illustrating successful approaches to difficult analytical problems across the basic scientific disciplines. Ion Trap Instrumentation, the second volume in the series, conveys an appreciation of the ion trap as a versatile instrument which is used successfully in research and in applications, often in tandem with other instruments or components, such as external ion sources and lasers. The book begins with a discussion of high resolution mass spectrometry and mass measurement accuracy. It then demonstrates that trajectories of high kinetic energy ions can be controlled so that such ions are confined. It provides applications of lasers to the study of trapped ions the laser photodissociation of gaseous ions confined within the ion trap. The book concludes with physics applications of the ion trap, in particular, the Penning trap and the Paul trap.
Download or read book Advances in Mass Spectrometry Volume 14 written by A.E. Hesso and published by Elsevier Science. This book was released on 1998-11-12 with total page 808 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of the 14th International Mass Spectrometry Conference was to cover all aspects of modern mass spectrometry including its rapidly growing applications in biochemistry, microbiology, immunology and molecular biology. Over 900 scientists attended the conference and more than 650 papers were presented. Features of this book: The articles in the 14th IMSC Proceedings have been divided between two media: paper and CD-ROM. The book contains 33 papers the CD-ROM has 300 additional papers. 1. The Proceedings part contains 300 papers from the oral and poster presentations. 2. The CD-ROM contains a copy of the book portion for search purposes, the conference abstract book, a QuickTime movie recording of the closing lecture given by Professor R. Graham Cooks. The 50 minute presentation has been divided into 8 parts to make the files smaller and a PDF file with images from the Congress.
Download or read book Practical Aspects of Trapped Ion Mass Spectrometry Volume V written by Raymond E. March and published by CRC Press. This book was released on 2016-04-19 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt: Widely used in medical research, pharmaceutical and fine chemicals industries, biological and physical sciences, and security and environmental agencies, mass spectrometry techniques are continually under development. In Practical Aspects of Trapped Ion Mass Spectrometry: Volume V, Applications of Ion Trapping Devices, an international panel of aut
Download or read book Practical Aspects of Ion Trap Mass Spectrometry written by Raymond E. March and published by CRC-Press. This book was released on 1995-09-18 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fundamentals of Ion Trap Mass Spectrometry presents an account of the development and theory of the quadrupole ion trap and its utilization as an ion storage device, a reactor for ion/molecular reactions, and a mass spectrometer. It also expands the appreciation of ion traps from that of a unique arrangement of electrodes of hyperbolic form (and having a pure quadrupole field) to a series of ion traps having fields with hexapole and octopole components and introduces the practical ion trapping device in which electrode spacing has been increased. The fundamentals of ion trap are covered in four chapters, beginning with the origin of the ion trap, its development and operating principles, and improvements in performance. The second part focuses on the environment within the ion trap -- the movement of ions within the trap -- and how this movement is modified by repeated collisions of the ions with buffer gas atoms of helium, and on the collisions of ions with molecules that lead to chemical change. The critical role of collisions in focusing the ion cloud for subsequent operations is emphasized. This important reference presents a coherent picture of the present status of research in the ion trapping field to facilitate the entree of potential ion trappers and provide a backdrop for ion trap research and development in the future.
Download or read book Ion Storage Techniques and Time of flight Mass Spectrometry in Physical Forensic Science written by and published by . This book was released on 2000 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Effective investigative analysis requires proper selection of sample-collection procedures, preservation, and analysis methods. To achieve these objectives it is essential to tailor the collection and analysis methods to the application requirements, which are constrained by different parameters such as analysis time, sample concentration, matrix interferences, and analyte stability (e.g., surface activity (''stickiness'') and chemical reactivity). In addition, method optimization must be accomplished without compromising sample integrity. Maintaining sample integrity requires minimizing and characterizing contamination as well as reducing sample degradation and loss to prevent both false positive and negative detection, respectively. When specific constraints are defined, depending on target chemical(s) and application scenarios, it is sometimes necessary to modify or develop new equipment and methods to best satisfy the application requirements. For this work, we are interested in real-time monitoring of airborne chemicals, which are commonly referred to as volatile organic compounds (VOC). Although there are a number of techniques for remote analysis of VOCs, many of these applications do not provide the specificity and sensitivity needed in real-time application scenarios. For example, spectroscopic techniques are capable of providing low part-per-billion volume/volume (ppb v/v) detection if a compound is distributed over a large area, however, they provide limited compound structural information. A different approach using air monitoring mass spectrometry can provide more specific chemical information in terms of compound molecular weight and structural information, however, preconcentration is required to achieve low ppb detection. Operation of the trap as a pulsed extraction eliminates many of the limitations that accompany operating the trap using mass selective axial ejection. As pulsed extraction source, the IS can be operated under high ion/ion and ion/neutral collision conditions without regard to perturbing ion secular motion. This permits overfilling of the IS and the use of air as a collisional damping gas with little effect on resolution and mass accuracy. A subsequent advantage of using air as a collisional damping gas is that it enhances ionization efficiency by providing a mechanism for chemical ionization. In addition to ion storage, the ion trap can be operated to deliver an ion packet with a spatial and kinetic energy distribution well suited for time-of-flight analysis. This mode of operation enhances sensitivity and resolution permitting the TOF-MS analyzer to be used effectively for real-time air monitoring. Among the different changes to trap operation needed for optimal operation, those modifications that minimize dispersion of the ion packet during extraction have the greatest effect on performance. Together these modifications, which include (1) phase synchronization, (2) RF clamping and (3) bipolar extraction, permit resolution of up to 1600 m/[Delta]m at FWHM and detection into the low ppb range for VOCs. Sensitivity for semi-VOCs is significantly lower and is attributed to adsorption loss in the IS envelop. We are currently investigating solutions to this limitation.
Download or read book Practical Aspects of Ion Trap Mass Spectrometry written by Raymond E. March and published by CRC Press. This book was released on 1995-10-23 with total page 542 pages. Available in PDF, EPUB and Kindle. Book excerpt: By delivering concentrated information in three different volumes, the editors of the Practical Aspects of Ion Trap Mass Spectrometry mini-series present in-depth reviews on mainstream developments in each active and popular area. Contributing authors provide concise reports illustrating successful approaches to difficult analytical problems across the basic scientific disciplines. Volume three, Chemical, Environmental, and Biomedical Applications, presents a coherent picture of research and applications in the ion trapping field. It examines tandem mass spectrometry, the principal mode of ion trap operation, where one stage of mass selectivity follows another in the same region of space. This volume discusses the fundamentals of ion trap theory, design, and operation; practical ion trap technology; applications involving small molecules; and the environmental and biomedical applications.
Download or read book Introduction to Mass Spectrometry written by J. Throck Watson and published by John Wiley & Sons. This book was released on 2013-07-09 with total page 972 pages. Available in PDF, EPUB and Kindle. Book excerpt: Completely revised and updated, this text provides an easy-to-read guide to the concept of mass spectrometry and demonstrates its potential and limitations. Written by internationally recognised experts and utilising "real life" examples of analyses and applications, the book presents real cases of qualitative and quantitative applications of mass spectrometry. Unlike other mass spectrometry texts, this comprehensive reference provides systematic descriptions of the various types of mass analysers and ionisation, along with corresponding strategies for interpretation of data. The book concludes with a comprehensive 3000 references. This multi-disciplined text covers the fundamentals as well as recent advance in this topic, providing need-to-know information for researchers in many disciplines including pharmaceutical, environmental and biomedical analysis who are utilizing mass spectrometry
Download or read book Charged particle Optics written by and published by . This book was released on 1999 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Mass Spectrometry written by Edmond de Hoffmann and published by Wiley. This book was released on 2001-10-10 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: Offers a complete overview of the principles, theories and key applications of modern mass spectrometry in this introductory textbook. Following on from the highly successful first edition, this edition is extensively updated including new techniques and applications. All instrumental aspects of mass spectrometry are clearly and concisely described; sources, analysers and detectors. * Revised and updated * Numerous examples and illustrations are combined with a series of exercises to help encourage student understanding * Includes biological applications, which have been significantly expanded and updated * Also includes coverage of ESI and MALDI
Download or read book Ion molecule Reactions written by Earl Wadsworth McDaniel and published by John Wiley & Sons. This book was released on 1970 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Fundamentals of Contemporary Mass Spectrometry written by Chhabil Dass and published by John Wiley & Sons. This book was released on 2007-05-11 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modern mass spectrometry - the instrumentation and applications in diverse fields Mass spectrometry has played a pivotal role in a variety of scientific disciplines. Today it is an integral part of proteomics and drug discovery process. Fundamentals of Contemporary Mass Spectrometry gives readers a concise and authoritative overview of modern mass spectrometry instrumentation, techniques, and applications, including the latest developments. After an introduction to the history of mass spectrometry and the basic underlying concepts, it covers: Instrumentation, including modes of ionization, condensed phase ionization techniques, mass analysis and ion detection, tandem mass spectrometry, and hyphenated separation techniques Organic and inorganic mass spectrometry Biological mass spectrometry, including the analysis of proteins and peptides, oligosaccharides, lipids, oligonucleotides, and other biological materials Applications to quantitative analysis Based on proven teaching principles, each chapter is complete with a concise overview, highlighted key points, practice exercises, and references to additional resources. Hints and solutions to the exercises are provided in an appendix. To facilitate learning and improve problem-solving skills, several worked-out examples are included. This is a great textbook for graduate students in chemistry, and a robust, practical resource for researchers and scientists, professors, laboratory managers, technicians, and others. It gives scientists in diverse disciplines a practical foundation in modern mass spectrometry.
