Download or read book A Pharmacology Primer written by Terry P. Kenakin and published by Academic Press. This book was released on 2018-10-26 with total page 489 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Pharmacology Primer: Techniques for More Effective and Strategic Drug Discovery, Fifth Edition features the latest ideas and research regarding the application of pharmacology to the process of drug discovery. Written by well-respected pharmacologist, Terry P. Kenakin, this primer is an indispensable resource for all those involved in drug discovery. This updated edition has been thoroughly revised to include material on quantifying drug efficacy through bias and cluster analysis, the impact of molecular dynamics and protein structural analysis, the real time kinetic analysis of drug effect, virtual screening for new drug chemical scaffolds, and much more. With full color illustrations and new examples throughout, this book remains a top reference for all industry and academic scientists that is also ideal for students directly involved in drug discovery or pharmacologic research. Highlights changes surrounding strategies for drug discovery, providing a comprehensive reference and featuring advances in the methods involved Includes multiple new sections, such as development and utilization of models in pharmacology, de-orphanization of new drug targets, predicting impact of disease on drug pharmacokinetics, and the impact of enzyme kinetics on drug-drug interactions Illustrates the application of rapid inexpensive assays to predict activity in the therapeutic setting, showing data outcomes and the limitations inherent in interpreting this data

Download or read book A Pharmacology Primer written by Terry P. Kenakin and published by Elsevier. This book was released on 2006-10-30 with total page 319 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Second Edition will continue this tradition of better preparing researchers in the basics of pharmacology. In addition, new human interest material including historical facts in pharmacology will be added. A new section on therapeutics will help readers identify with diseases and drug treatments. Over 30 new figures and tables More human interest information to provide readers with historical facts on pharmacology research New section on therapeutics to help identify diseaes and drug treatments New section on new biological concepts relevant to pharmacological research (i.e., systems biology) New study sections organized with ASPET and other international pharmacology organizations New coverage of pharmacokinetics and drug disposition

Download or read book A Pharmacology Primer written by Terry P. Kenakin and published by Elsevier. This book was released on 2014-03-26 with total page 451 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Pharmacology Primer: Techniques for More Effective and Strategic Drug Discovery, 4th Edition features the latest ideas and research about the application of pharmacology to the process of drug discovery to equip readers with a deeper understanding of the complex and rapid changes in this field. Written by well-respected pharmacologist, Terry P. Kenakin, this primer is an indispensable resource for all those involved in drug discovery. This edition has been thoroughly revised to include material on data-driven drug discovery, biased signaling, structure-based drug design, drug activity screening, drug development (including pharmacokinetics and safety Pharmacology), and much more. With more color illustrations, examples, and exercises throughout, this book remains a top reference for all industry and academic scientists and students directly involved in drug discovery, or pharmacologic research. - Highlights changes surrounding the strategy of drug discovery to provide you with a comprehensive reference featuring advances in the methods involved in lead optimization and more effective drug discovery - Includes a new chapter on data-driven drug discovery in terms of the optimal design of pharmacological experiments to identify mechanism of action of new molecules - Illustrates the application of rapid inexpensive assays to predict activity in the therapeutic setting, showing data outcomes and the limitations inherent in interpreting this data

Download or read book A Primer of Drug Action written by Robert M. Julien and published by Macmillan + ORM. This book was released on 2013-08-06 with total page 755 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since 1975, Robert Julien's A Primer of Drug Action has been the definitive guide to the effects of psychoactive drugs on the brain and on behavior. Now fully updated, this popular guide continues to lead the way through a rapidly changing field, providing readers with a clear, contemporary, and objective look at every drug and medication that either positively or adversely affects brain function. This edition includes important new information on: -Herbal medications -Drug therapy for behavioral and anxiety disorders -Clinical practice guidelines for treating psychological disorders -Depression and the action of antidepressant drugs -The use of newer anticonvulsants in the treatment of bipolar disorder, pain syndromes, and behavioral disorders -Drug therapy for children, adolescents and the elderly -"New generation" antipsychotic agents Authoritative, comprehensive, and suitable for those with little background in biology, A Primer of Drug Action is an indispensable source of information for anyone interested in drug use, abuse, and education.

Download or read book Medication Workbook for Pharmacy Technicians A Pharmacology Primer written by David R. Bright and published by Morton Publishing Company. This book was released on 2012-01-01 with total page 359 pages. Available in PDF, EPUB and Kindle. Book excerpt: Officially endorsed by the American Pharmacists Association (APhA), this practical workbook provides a basic introduction to pharmacology and reinforces the use of medications for prospective technicians to work in a pharmacy and to help prepare them for the pharmacy technician national certification exams.

Download or read book Essential Pharmacokinetics written by Thorsteinn Loftsson and published by Academic Press. This book was released on 2015-03-25 with total page 179 pages. Available in PDF, EPUB and Kindle. Book excerpt: Essential Pharmacokinetics: A Primer for Pharmaceutical Scientists is an introduction to the concepts of pharmacokinetics intended for graduate students and new researchers working in the pharmaceutical sciences. This book describes the mathematics used in the mammillary model as well as the application of pharmacokinetics to pharmaceutical product development, and is useful as both a self-study and classroom resource. Content coverage includes detailed discussions of common models and important pharmacokinetic concepts such as biological half-life, clearance, excretion, multiple dosage regimens and more. Numerous equations, practical examples and figures are incorporated to clearly illustrate the theoretical background of pharmacokinetic behavior of drugs and excipients. - Shows how to apply basic pharmacokinetic methods to evaluate drugs, excipients and drug products - Uses guided practice questions, mathematical concepts and real-world examples for self-assessment and retention purposes - Illustrates how to write and evaluate drug registration files

Download or read book PHARMACOLOGY PRIMER written by TERRY. KENAKIN and published by . This book was released on 2023 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Elements of Pharmacology written by P. J. Bentley and published by Cambridge University Press. This book was released on 1981-08-31 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written primarily for students of medicine, pharmacy, and pharmacology, this introductory book provides a concise summary of the principles that underlie the science of pharmacology. It presents the basic concepts required for understanding the use, mechanisms of action, toxicity and side effects, and therapeutic application of drugs in man. Thus the book may also be of interest to medical practitioners and to biological and medical scientists. Among topics covered are the sources of drugs, the way they are administered and dealt with in the body, as well as concepts about the nature of their actions. The last include their chemical interactions with components of cells and the manner in which these lead to therapeutically desirable as well as undesirable and even toxic effects. In addition, clinically related subjects, such as drug interactions, teratogenic and carcinogenic effects are discussed. The development and testing of new drugs are also described. For easy reference, at the back of the book there is a glossary of drugs named in the text.

Download or read book A Pharmacology Primer written by Terry P. Kenakin and published by Academic Press. This book was released on 2009-02-07 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: This successful guide assists scientists trained in molecular biology and related fields who now need to know the basic theories, principles and practical applications of pharmacology. This latest edition continues the tradition of better preparing researchers in the basics of pharmacology. With expanded hands-on exercises and the addition of Pharmacokinetics coverage, new human interest material including historical facts in pharmacology and a new section on therapeutics that will help readers identify with diseases and drug treatments.The ideal book for researchers in drug discovery who have seen their role shift from "individual" to "team player" where that team includes chemists, biologists, and others with strong, but varied, science backgrounds who must now work together toward their common pharmacology goal. At GlaxoSmithKline, a pharmaceuticals world-leader, Terry Kenakin regularly teaches a course for their research scientists and has drawn on his experience to create a pharmacology primer.*New - Latest coverage of the chemistry of drugs including expanded coverage of the pharmacokinetic discussion of druglike properties -- Increases reader understanding of necessary ADME (Absorption, Distribution, Metabolism, and Excretion) properties and increases the rate of drug approval and acceptance. *Context - Unique discussions on various drug discovery teams and the role of the chemist on those teams -- Promotes the understanding of these expanding roles and responsibilities and how to maximize the effective contributions of each matrix team member. *Real-world learning - There are hands-on exercises, with extensive answers, utilizing real data on structure activity relationships; utilization of pharmacological principles to make general statements about how changes in structure lead to changes in drug activity. + hands on exercises with extensive answers on Pharmacokinetics -- Stengthens practical application and understanding of core concepts and principles.*Study sections are organized with ASPET (American Society for Pharmacology and Experimental Therapeutics)and other international organizations -- Ensures that learning follows professional industry standards.

Download or read book Pharmacology Primer for Medications in Nuclear Medicine and Medical Imaging written by Geoffrey Currie and published by . This book was released on 2020-11 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book A Pharmacology Primer written by Terry Kenakin and published by Academic Press. This book was released on 2018-11-05 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Pharmacology Primer: Techniques for More Effective and Strategic Drug Discovery, Fifth Edition features the latest ideas and research regarding the application of pharmacology to the process of drug discovery. Written by well-respected pharmacologist, Terry P. Kenakin, this primer is an indispensable resource for all those involved in drug discovery. This updated edition has been thoroughly revised to include material on quantifying drug efficacy through bias and cluster analysis, the impact of molecular dynamics and protein structural analysis, the real time kinetic analysis of drug effect, virtual screening for new drug chemical scaffolds, and much more. With full color illustrations and new examples throughout, this book remains a top reference for all industry and academic scientists that is also ideal for students directly involved in drug discovery or pharmacologic research.

Download or read book Julien s Primer of Drug Action written by Claire D. Advokat and published by Macmillan Higher Education. This book was released on 2018-07-27 with total page 656 pages. Available in PDF, EPUB and Kindle. Book excerpt: Julien's Primer of Drug Action continues to evolve side by side with the field it covers providing a thoroughly up to date look at psychotherapeutic and recreational drugs, including the latest research and the newest formulations. The thoroughly updated 14th edition features: New coverage of opioids of abuse, and drugs used to treat of opioid dependence and opioid overdose. New research on the use of marijuana to treat Alzheimers, PTSD, and Epilepsy. New coverage of pharmacological, physiological, and psychoactive effects of synthetic marijuana including its toxicity. New research on Cannabidiol (CBD) and its therapeutic uses New research of the efficacy of antipsychotics to treat dementia, Parkinson's, bipolar, OCD, PTSD, New research on hallucinogenics for the treatment of various disorders including MDMA for the treatment of PTSD, Psilocybin for treatment of depression and end-of-life anxiety, and Ayahuasca to treat psychiatric disorders The use of genetic testing to predict effectiveness of antidepressant treatment New research on the use of ketamine for the treatment of depression

Download or read book Pharmacology for Chemists written by Raymond Hill and published by Royal Society of Chemistry. This book was released on 2017-10-30 with total page 538 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook explains the key issues in pharmacology to chemists interested in or planning to work in drug discovery.

Download or read book The Pharmacy Informatics Primer written by Doina Dumitru and published by ASHP. This book was released on 2008-09-30 with total page 265 pages. Available in PDF, EPUB and Kindle. Book excerpt: The information technology revolution has fueled the demand in hospitals and health systems for accomplished experts who can help select, implement and maintain CPOE, BCMA, EHR and other systems. As the use of IT in healthcare expands and the complexity of medication therapy increases, there has been a correspondingly rapid growth in the practice of pharmacy informatics and a basic need for an understanding of key elements. The Pharmacy Informatics Primer provides a foundational understanding and offers “pearls of wisdom” for pharmacy professionals involved in informatics. This introductory resource outlines key concepts in understanding, developing, implementing, and maintaining clinical information and automation systems. This essential guide is designed for all pharmacists and covers an introduction to major concepts of informatics such as ePrescribing, CPOE, bar-coding, smart pumps, and the pharmacist’s role in EHR. Chapter features include key terms and definitions, and a comprehensive table of pearls, specific to each subject to present a clear understanding of all concepts.

Download or read book Drug Discovery and Development written by Ramarao Poduri and published by Springer Nature. This book was released on 2021-02-15 with total page 522 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the processes that are involved in the development of new drugs. The authors discuss the history, role of natural products and concept of receptor interactions with regard to the initial stages of drug discovery. In a single, highly readable volume, it outlines the basics of pharmacological screening, drug target identification, and genetics involved in early drug discovery. The final chapters introduce readers to stem therapeutics, pharmacokinetics, pharmacovigilance, and toxicological testing. Given its scope, the book will enable research scholars, professionals and young scientists to understand the key fundamentals of drug discovery, including stereochemistry, pharmacokinetics, clinical trials, statistics and toxicology.

Download or read book Regenerative Pharmacology written by George J. Christ and published by Cambridge University Press. This book was released on 2013-04-15 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: A state-of-the-art primer on the role of pharmacological sciences in regenerative medicine, for advanced students, postdoctoral fellows, and researchers.

Download or read book Introduction to Behavioral Pharmacology written by Thomas Byrne and published by New Harbinger Publications. This book was released on 2000-05-01 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: There are hundreds, if not thousands, of substances that are used to modify behavior. While different classes of substances have known effects, one has only to see a group of people drinking to excess to recognize that not everyone responds in the same way to a given substance. Why do substances have the behavioral effects they do, and why do individuals vary in their responses to them? This book provides a conceptual framework for answering such questions. Introduction to Behavioral Pharmacology includes a short overview of behavioral analysis and general pharmacology, followed by detailed discussion of assessment of drug effects, the stimulus properties of drugs, drug abuse, and more.