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Book A Comparison of the Antimicrobial Efficacy of Silver Diamine Fluoride and Silver Nitrate on Various Cariogenic Bacteria

Download or read book A Comparison of the Antimicrobial Efficacy of Silver Diamine Fluoride and Silver Nitrate on Various Cariogenic Bacteria written by Reham AlNajjar and published by . This book was released on 2019 with total page 23 pages. Available in PDF, EPUB and Kindle. Book excerpt: Purpose: The use of silver-based antimicrobials is an emerging method for the treatment of dental caries. In this study, the authors compare the efficacy of the two most prominent silver- based therapeutics, silver diamine fluoride (SDF) and silver nitrate (AgNO3), on cariogenic and non-cariogenic multispecies biofilms. Currently there is a lack of studies comparing the efficacy of SDF to AgNO3. Methods: Plaque samples from anterior and posterior tooth sites from children presenting both with early childhood caries and caries-free children were collected, pooled, and utilized to create four ex vivo biofilm systems in artificial saliva. SDF and AgNO3 were administered to these biofilms and bacterial survival was quantified and compared to untreated controls. Results: Each of the four pooled sample types was applied to plates coated in artificial saliva + 1% sucrose. Both SDF and AgNO3 were very effective against plaque derived biofilms when compared to untreated biofilms (P0.05) in the potency of each compound. Conclusions: SDF and AgNO3 significantly inhibit ex vivo cariogenic and non-cariogenic biofilms at similar levels.

Book A Comparison of the Antimicrobial Efficacy of Silver Diamine Fluoride and Silver Nitrate

Download or read book A Comparison of the Antimicrobial Efficacy of Silver Diamine Fluoride and Silver Nitrate written by Nicholas L. Luke and published by . This book was released on 2018 with total page 27 pages. Available in PDF, EPUB and Kindle. Book excerpt: Purpose: To determine the antimicrobial efficacy of SDF and SN/NaF. Methods: Three bacterial species were combined to create an in vitro biofilm. Treatment was completed with SN, SN/NaF, SDF, SDF1⁄2 or untreated (control). Results: The untreated group demonstrated significantly higher growth than all other treatment groups across the study. On the BHI-plates (1-day), there were significant differences between all treatments except SDF and SDF1⁄2. On the BHI-plates (3-days), SN/NaF was not significantly different from SDF or SDF1⁄2. On the L-MRS-plates (1-day), both SN treatment groups yielded significantly higher growth than the SDF groups. On the L-MRS-plates (3-days), SN yielded significantly higher growth than SN/NaF, SDF, and SDF1⁄2. Conclusion: SDF is more effective than SN/NaF, with the exception of BHI-plates (3-days) only and SN/NaF is more effective than SN on primarily S. mutans and L. acidophilus. There is evidence of a possible antimicrobial tolerance of oral bacteria to silver.

Book ANTIMICROBIAL EFFECTS IN VITRO OF SILVER DIAMINE FLUORIDE AGAINST SELECTED HUMAN RED AND ORANGE COMPLEX PERIODONTAL PATHOGENS

Download or read book ANTIMICROBIAL EFFECTS IN VITRO OF SILVER DIAMINE FLUORIDE AGAINST SELECTED HUMAN RED AND ORANGE COMPLEX PERIODONTAL PATHOGENS written by Guillermo Jose Ramirez-Martinez and published by . This book was released on 2019 with total page 35 pages. Available in PDF, EPUB and Kindle. Book excerpt: Objectives: Silver diamine fluoride is approved by the United States Food and Drug Administration for intraoral human treatment of tooth hypersensitivity, and it has also been employed world-wide as an emerging method to arrest tooth decay. A 38% silver diamine fluoride formulation, comprised of 25% silver, 5% fluoride, and 8% ammonia as a solvent, is commercially available in the United States. One of the main mechanisms underlying the dental caries arrest potential of silver diamine fluoride is the silver component, which exerts pronounced antimicrobial activity against cariogenic bacteria. Interestingly, studies initiated in the late 1990s demonstrated marked susceptibility of periodontal bacterial pathogens to silver nitrate. However, efforts to develop silver-based, slow-release biodegradable wafers for subgingival placement into periodontal pockets were not commercially successful. At present, no commercial products are available which employ silver ions to combat periodontal bacterial pathogens in periodontal disease treatment. It is not known whether the 38% silver diamine fluoride product commercially available in the United States possesses antimicrobial activity against periodontal bacterial pathogens, and potentially, have application in periodontal therapeutic regimens. As a result, the objective of this study was to test the in vitro antimicrobial effects of silver diamine fluoride on freshly-isolated red and orange complex periodontal pathogens from severe human periodontitis lesions. Methods: Paper point subgingival biofilm samples from 24 adults with severe periodontitis that were to be discarded after microbiological analysis at the Temple University School of Dentistry Oral Microbiology Testing Service Laboratory were secondarily employed in this study. Dilution aliquots from each subgingival specimen were mixed with either 38% or 19% silver diamine fluoride, inoculated onto enriched Brucella blood agar plates, and incubated anaerobically for 7 days at 37°C. Bacterial species growing subsequent to the silver diamine fluoride exposure were considered to be resistant to that concentration of silver diamine fluoride. Total viable counts in silver diamine fluoride-exposed subgingival specimens were quantitated, and established phenotypic criteria employed to identify the following red and orange complex periodontal pathogens: Porphyromonas gingivalis, Tannerella forsythia, Prevotella intermedia/nigrescens, Parvimonas micra, Campylobacter rectus, Fusobacterium nucleatum group species, and Streptococcus constellatus. Other cultivable isolates recovered from silver diamine fluoride-exposed subgingival specimens were identified using matrix-assisted laser desorption-ionization time-of-flight (MALDI-TOF) mass spectrometry and Bruker MALDI Biotyper analytic software. Subgingival sample dilution aliquots not exposed to silver diamine fluoride were similarly processed as controls for comparison with silver diamine fluoride-exposed specimens Paired t-tests compared mean total subgingival viable counts, and mean total subgingival proportions of the evaluated anaerobic red and orange complex periodontal pathogens per patient, between subgingival biofilm samples exposed and not exposed in vitro to 38% or 19% silver diamine fluoride, with a P-value of

Book Actions of Silver Diamine Fluoride on Dentine Caries and Its Caries Preventive Effect with Laser Irradiation

Download or read book Actions of Silver Diamine Fluoride on Dentine Caries and Its Caries Preventive Effect with Laser Irradiation written by Leticia Ito and published by . This book was released on 2017-01-26 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This dissertation, "Actions of Silver Diamine Fluoride on Dentine Caries and Its Caries Preventive Effect With Laser Irradiation" by Leticia, Ito, was obtained from The University of Hong Kong (Pokfulam, Hong Kong) and is being sold pursuant to Creative Commons: Attribution 3.0 Hong Kong License. The content of this dissertation has not been altered in any way. We have altered the formatting in order to facilitate the ease of printing and reading of the dissertation. All rights not granted by the above license are retained by the author. Abstract: The effect of silver diamine fluoride (SDF) on the mineral content of carious dentine and the preventive caries effect of erbium-doped yttrium aluminium garnet (Er: YAG) laser irradiation (2,940 nm) combined with SDF application under cariogenic biofilm challenge model was investigated. Firstly, the SDF mechanism of action in the remineralisation of demineralised dentine process observing changes in the mineral content in vitro was investigated. Secondly, we investigated the effect of various laser irradiations at sub-ablative energy levels on the fluoride uptake of 38% SDF treated dentine. Finally, we evaluated the effects of Er: YAG laser irradiation combined with SDF application on the fluoride uptake by dentine under a cariogenic biofilm challenge. Compared with a 10% sodium fluoride and potassium fluoride solution and a 42% silver nitrate solution with the same content of fluoride and silver respectively, 38% SDF is more effective in promoting remineralisation of demineralised dentine. The dentine samples treated with SDF did not show evident demineralised surface morphology. Although the lesion depth for SDF treated samples was not significantly deeper than for sodium fluoride treated samples, it was demonstrated that SDF has an inhibitory effect on dentine demineralization. The results of the SDF-laser experiment showed that carbon dioxide (CO2) laser irradiation (10,600 nm) followed by Er: YAG laser irradiation at specific sublablative levels promoted the higher fluoride uptake from SDF application than neodymium-doped yttrium aluminium garnet(Nd: YAG) laser (1,064 nm) and diode laser (810 nm) irradiation. This study provides guidelines for the selection of the appropriate laser irradiation parameters and types to promote an optimal level of fluoride uptake for dentine caries prevention. Er: YAG laser irradiation was elected among the laser types in the previous experiment for promoting higher levels of fluoride uptake and for its maximal absorption by water and high absorption by hydroxyapatite. The Er: YAG SDF-laser treated dentine was subjected cariogenic bacterial challenge to investigate the caries preventive effect of this treatment. The morphological surface of the treated samples presented many occluded dentinal tubules. There was a major increase in the hardness and elastic moduli values and the fluoride content also increased significantly after the remineralisation process. To conclude, this study demonstrated that SDF application inhibited dentine demineralization and arrested caries, and that SDF application followed by Er: YAG laser irradiation promoted an increase in fluoride uptake by sound dentine under a cariogenic biofilm challenge. Subjects: Fluorides - Therapeutic use Dental caries - Prevention

Book The Root Canal Biofilm

    Book Details:
  • Author : Luis E. Chávez de Paz
  • Publisher : Springer
  • Release : 2015-10-20
  • ISBN : 3662474158
  • Pages : 369 pages

Download or read book The Root Canal Biofilm written by Luis E. Chávez de Paz and published by Springer. This book was released on 2015-10-20 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the current state of research on the basic scientific aspects of root canal biofilm biology within a clinically applicable context. Root canal biofilms are complex polymicrobial structures adhering to the root canal surface that are formed by microorganisms invading the pulpal space of teeth, and are associated with persistent root canal infections. Concerted efforts to study root canal biofilms have been made in the past decade, resulting in the publication of observational and experimental studies that detail the morphology and biology of these structures in infected root canals. In addition to confirming that bacteria in root canals do not exist in free-floating planktonic states as previously assumed, this new information on root canal biofilm infections has provided an opportunity to re-evaluate conventional clinical protocols and improve endodontic therapeutic measures.

Book Smart Nanodevices for Point of Care Applications

Download or read book Smart Nanodevices for Point of Care Applications written by Suvardhan Kanchi and published by CRC Press. This book was released on 2022-06-23 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: Smart Nanodevices for Point-of-Care Applications examines the latest trends on the capabilities of nanomaterials for point-of-care (PoC) diagnostics and explains how these materials can help to strengthen, miniaturize, and improve the quality of diagnostic devices. A thorough explanation of all-in-one nanosmart devices is included, incorporating all of the applications and fundamentals of these smart devices. This book provides practical information on the following: novel and effective smart materials, better-quality health management, effective management of a disease, potential point-of-care devices, and mobile nanosensors. Additional Features Includes in-depth research based collation of the latest trends of smart devices Provides practical information on all-in-one nanosmart devices Explains how nanomaterials can help to strengthen and improve the quality of diagnostic devices Emphasizes the development of smart nanodevices, especially the miniaturization aspect

Book Silver Diamine Fluoride

Download or read book Silver Diamine Fluoride written by Karthika D and published by Clever Fox Publishing. This book was released on with total page 74 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dental caries specifically ECC, remains a remarkable issue in certain parts of society, particularly those with low socioeconomic status and with scarce health care services. Techniques that promote less discomfort, such as the application of silver diamine fluoride, should be preferred and considered. Treatment of the disease is needed as children with an active caries lesion in their primary dentition can also present with caries lesions in their permanent dentition. By arresting and preventing the progression of caries, SDF offers an intervening care path for young children for whom traditional restorative treatment is not instantly available nor unacceptable by the children. This book on SDF highlights the properties of SDF and clinical recommendations on its use, safety for clinicians, the pros and cons of SDF solution in the clinical use of young children.

Book Effects of Silver Diamine Fluoride on Oral Bacteriome and Mycobiome

Download or read book Effects of Silver Diamine Fluoride on Oral Bacteriome and Mycobiome written by Mayura Manerkar and published by . This book was released on 2022 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction: Silver diamine fluoride (SDF) is a simple and non-invasive agent to arrest caries in children. The purpose of this study is to investigate changes to the oral bacteriome and mycobiome in young children treated with SDF Methods: Plaque samples were collected from 45 children with early childhood caries (ECC). Frequency regimens of SDF were two applications 4 months apart (4M), two applications 6 months apart (6M), and two applications 1 month apart (1M). DNA was extracted and sent to Genome Quebec Innovation Center for library preparation and paired-end Illumina MiSeq PE300 sequencing of the V4 region of bacterial 16S rRNA and fungal ITS1 rRNA genes. Sequencing data was analyzed using QIIME2 2018.11. Results: A total of 195 carious lesions in 44 children were treated at baseline and followed over two subsequent study visits. The overall arrest rates were 77.69% at Visit 2 and 93.61% at Visit 3 respectively. Arrest rates were higher for all lesions after two applications of SDF. The alpha diversity and beta diversity analysis showed no significant differences in the supragingival bacteriome and mycobiome for all three regimens. Taxonomic assignment showed that Streptococcus, Corynebacterium and Actinomyces were the most abundant genera for Bacteria and Candida, Blumeria, and Malassezia were the most abundant genera for Fungi. Streptococcus mutans and Veillonella dispar both showed a decrease in relative abundance, but these changes were a trend and not found to be statistically significant. Candida albicans was highly abundant in all groups regardless of number of visits or regimens. The differential abundance analysis showed significant changes in both bacterial and fungal species, particularly Lactobacillus spp., Bifidobacterium spp. and Candida spp. Our study found a vast diversity of fungal species and differential abundance analysis suggested that SDF treatment may have an effect on the abundance of specific fungi. Conclusion: SDF was an effective modality for arresting dental caries with higher arrest rates for all lesions after two applications of SDF. Further studies with a larger sample size are needed to confirm whether the presence or absence of various bacterial and fungal species are the result of SDF application at various frequencies.

Book Pediatric Restorative Dentistry

Download or read book Pediatric Restorative Dentistry written by Soraya Coelho Leal and published by Springer. This book was released on 2018-09-11 with total page 227 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes and discusses the different restorative options for managing carious lesions in children with primary and mixed dentition. The aim is to provide practitioners with thorough, up-to-date information that will improve their clinical practice. The opening chapters present a comprehensive overview regarding diagnosis of carious lesions, risk assessment, child behavior and development, and behavioral management. The importance of oral health promotion and prevention in controlling lesion progression and maintaining oral health is reviewed. The impact of various factors on clinician decision making is then explained in detail, examples including the type of dentition (primary versus permanent), the clinical and radiographic aspect of the dentine carious lesion (noncavitated or cavitated), and whether the lesion is associated with a developmental defect. Guidance is provided on selection of nonoperative versus operative interventions, and the restorative materials most frequently used in pediatric dentistry are fully described, highlighting their advantages and disadvantages. Readers will also find an informative series of cases, with explanation of the choices in terms of materials and approach.

Book Effectiveness of Silver Diamine Fluoride and Sodium Fluoride Varnish in Arresting Dentine Caries

Download or read book Effectiveness of Silver Diamine Fluoride and Sodium Fluoride Varnish in Arresting Dentine Caries written by Chun-Hung Chu and published by . This book was released on 2017-01-27 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This dissertation, "Effectiveness of Silver Diamine Fluoride and Sodium Fluoride Varnish in Arresting Dentine Caries" by Chun-hung, Chu, 朱振雄, was obtained from The University of Hong Kong (Pokfulam, Hong Kong) and is being sold pursuant to Creative Commons: Attribution 3.0 Hong Kong License. The content of this dissertation has not been altered in any way. We have altered the formatting in order to facilitate the ease of printing and reading of the dissertation. All rights not granted by the above license are retained by the author. Abstract: Abstract of thesis entitled Effectiveness of silver diamine fluoride and sodium fluoride varnish in arresting dentine caries submitted by Chu Chun Hung for the degree of Doctor of Philosophy at the University of Hong Kong in May 2004 Introduction: Caries prevalence in young children in China is high and most of the decayed teeth are left untreated. Conventional dental treatments are either not available or are unaffordable in many rural areas. Innovative approaches are needed to improve this situation. Aim: This prospective clinical trial investigated the effectiveness of topical fluoride applications in arresting dentine caries. The first null hypothesis to be tested was that there were no differences in the effectiveness of applying a 38% silver diamine fluoride (SDF) solution (44,800 ppm F), a 5% sodium fluoride (NaF) varnish (22,600 ppm F) and water in arresting dentine caries. The second null hypothesis was that caries removal prior to fluoride application had no impact on its effectiveness in arresting dentine caries. Methods: A total of 375 Chinese kindergarten children, aged 3-5 years with carious upper anterior teeth were divided into five groups. Children in the first and second groups received annual applications of SDF. NaF was applied every three months onto the lesions of children in the third and fourth groups. For children in the first and third groups, soft carious tissues were removed with hand instruments prior to fluoride application at the baseline examination. The fifth group of children received annual applications of water. Follow-up examinations were performed every six months. The children's parents completed a questionnaire to assess parental satisfaction with the appearance of the upper anterior teeth of their child before treatment and again at 24 months after treatment. Results: A total of 308 children were followed for 30 months. The respective mean numbers of arrested caries tooth surfaces in the five groups of children were 2.5, 2.8, 1.5, 1.5 and 1.3 (pDOI: 10.5353/th_b3016250 Subjects: Dental caries - Prevention Dental caries in children Fluorides - Therapeutic use Sodium fluoride - Therapeutic use

Book ACTIONS OF CHLORHEXIDINE   SIL

    Book Details:
  • Author : Managing Partner Lei Mei
  • Publisher : Open Dissertation Press
  • Release : 2017-01-24
  • ISBN : 9781360971964
  • Pages : 190 pages

Download or read book ACTIONS OF CHLORHEXIDINE SIL written by Managing Partner Lei Mei and published by Open Dissertation Press. This book was released on 2017-01-24 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt: This dissertation, "Actions of Chlorhexidine and Silver Diamine Fluoride on Cariogenic Biofilm and Root Caries" by Lei, Mei, 梅蕾, was obtained from The University of Hong Kong (Pokfulam, Hong Kong) and is being sold pursuant to Creative Commons: Attribution 3.0 Hong Kong License. The content of this dissertation has not been altered in any way. We have altered the formatting in order to facilitate the ease of printing and reading of the dissertation. All rights not granted by the above license are retained by the author. DOI: 10.5353/th_b4490077 Subjects: Chlorhexidine Sodium fluoride - Therapeutic use Teeth - Roots Dental caries Biofilms

Book Early Childhood Oral Health

Download or read book Early Childhood Oral Health written by Joel H. Berg and published by John Wiley & Sons. This book was released on 2015-10-26 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dental caries has been called a “silent epidemic” and is the most prevalent chronic disease affecting children. Though much has been written on the science and practice of managing this disease, publications are diverse in their loci, preventing easy access to the reader. Early Childhood Oral Health coalesces all the important information related to this topic in a comprehensive reference for students, academics, and practitioners. This second edition expands the scope of the first and puts an additional focus on interprofessional and global efforts that are necessary to manage the growing disease crisis and screening and risk assessment efforts that have expanded with the boom of new technologies. With updated references and incorporating the latest research, chapters address the biology and epidemiology of caries, the clinical management of early childhood caries, risk assessment, and early diagnosis. Other topics include public health approaches to managing caries worldwide, implementation of new caries prevention programs, fluoride regimens, and community programs, and family oral health education. Brand new are four chapters on the medical management of early childhood caries, considerations for children with special needs, interprofessional education and practice, and how the newest policy issues and the Affordable Care Act affect dental care. A must-read for pediatric dentists, cariologists, public health dentists, and students in these fields, Early Childhood Oral Health is also relevant for pediatricians and pediatric nursing specialists worldwide.

Book The Effectiveness of Silver Diamine Fluoride when Used to Arrest Caries in Children and Associated Oral Health related Quality of Life

Download or read book The Effectiveness of Silver Diamine Fluoride when Used to Arrest Caries in Children and Associated Oral Health related Quality of Life written by Rena Sihra and published by . This book was released on 2019 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Objective: To investigate the efficacy of silver diamine fluoride (SDF) with 5% fluoride varnish (FV) in treating cavitated caries in young children and to explore the association between SDF treatment and oral health-related quality of life (OHRQoL). Methods: Children with active dentinal caries lesions (ICDAS 5 or 6) in primary teeth underwent treatment with 38% SDF and 5% FV at baseline and 4 months later. Treated lesions were assessed 4 and 8 months after baseline to determine arrest. Participants were deemed Completely Successful (CS) if all treated lesions were arrested and Incompletely Successful (IS) if at least one lesion was not arrested. The early childhood oral health impact scale (ECOHIS) questionnaire was completed at second and third visits. Statistical analyses included descriptive and bivariate methods. A P value ≤ 0.05 was significant. Results: Forty children with 239 caries lesions were enrolled; mean age 40.2 +/- 14.9 months and 45% male. Lesion arrest rates after one and two applications of SDF were 74.1% and 96.2%, respectively. Children who reportedly brushed twice daily were more likely to be in the CS group compared to those who brushed less (p=0.006). Participants in the CS group had a significantly lower mean baseline dmft score than those in the IS group (p= 0.048). No significant difference in OHRQoL was observed between CS and IS groups. Conclusions: SDF with 5% FV is an effective approach to the management of ECC; more than one application is recommended along with regular follow-up of patients and twice daily brushing. OHRQoL was not found to be affected by the level of success of SDF treatment.

Book Dental Composite Materials for Direct Restorations

Download or read book Dental Composite Materials for Direct Restorations written by Vesna Miletic and published by Springer. This book was released on 2017-11-25 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers both basic scientific and clinically relevant aspects of dental composite materials with a view to meeting the needs of researchers and practitioners. Following an introduction on their development, the composition of contemporary composites is analyzed. A chapter on polymerization explains the setting reactions and light sources available for light-cured composites. The quality of monomer-to-polymer conversion is a key factor for material properties. Polymerization shrinkage along with the associated stress remains among the most challenging issues regarding composite restorations. A new classification of dental composites is proposed to offer more clinically relevant ways of differentiating between commercially available materials. A review of specific types of composites provides an insight into their key issues. The potential biological issues of dental composites are reviewed in chapters on elution of leachable substances and cariogenicity of resin monomers. Clinical sections focus on material placement, finishing procedures, and the esthetics and clinical longevity of composite restorations. Bonding to tooth tissues is addressed in a separate chapter, as is the efficiency of various composite repair methods. The final chapter discusses future perspectives on dental composite materials.

Book Effectiveness of Silver Diamine Fluoride Solution in Arresting Early Childhood Caries

Download or read book Effectiveness of Silver Diamine Fluoride Solution in Arresting Early Childhood Caries written by Ho-Tak Marcus Fung and published by Open Dissertation Press. This book was released on 2017-01-27 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This dissertation, "Effectiveness of Silver Diamine Fluoride Solution in Arresting Early Childhood Caries" by Ho-tak, Marcus, Fung, 馮浩德, was obtained from The University of Hong Kong (Pokfulam, Hong Kong) and is being sold pursuant to Creative Commons: Attribution 3.0 Hong Kong License. The content of this dissertation has not been altered in any way. We have altered the formatting in order to facilitate the ease of printing and reading of the dissertation. All rights not granted by the above license are retained by the author. Abstract: Early childhood caries (ECC) is the most prevalent oral disease of children worldwide. Epidemiological studies reported that most of the ECC are left untreated. While young children may not be co-operative enough for conventional restorative treatments, silver diamine fluoride (SDF) can be topically applied on tooth surfaces as a cariostatic agent. Previous clinical trials have confirmed that annual application of 38% SDF is effective in arresting dentin caries in preschool children. However, information about the effectiveness of SDF with different combinations of concentration and frequency is still lacking. This information is important for the optimal application of SDF in the future public health programs for caries control. This prospective randomized controlled trial aimed to investigate and compare the effectiveness of 12% and 38% SDF when applied annually or biannually in arresting dentin caries of primary teeth of preschool children for 30 months. The two null hypotheses tested were firstly, there is no difference in effectiveness when SDF is applied at 12% or 38% in arresting dentin caries of preschool children; and secondly, there is no difference in effectiveness when SDF is applied annually or biannually in arresting dentin caries of preschool children. A total of 888 healthy and cooperative K1 children aged 3-4 years with at least one dentin caries surface were recruited and randomized into four treatment groups: Group 1 received annual applications of 12% SDF, Group 2 received biannual applications of 12% SDF, Group 3 received annual applications of 38% SDF, and Group 4 received biannual applications of 38% SDF. Group 3 was assigned as the positive control group. Primary outcome was soft dentin caries surface at baseline that became arrested at the follow-up examinations. Clinical examinations were conducted at the kindergartens every 6 months by the same trained examiner. Parental questionnaires were used to collect the children's demographic information, oral hygiene related habits, parental satisfaction with children's dental appearance and dental health at baseline, 18- and 30-month examinations. Adverse effects after treatments including increment of non-vital teeth, complaint about tooth or gingival discomfort, gingival discoloration, and black staining over arrested surfaces were also recorded. A total of 798 children with 3,268 caries surfaces were examined at 30-month follow-up. The dropout rates of the four groups were similar. The respective proportions of arrested surfaces in Group 1 to Group 4 were 48.7%, 54.0%, 60.6%, and 66.9%, respectively (p To conclude, SDF is more effective in arresting dentin caries in primary teeth of preschool children at 38% than 12%, and when applied biannually than annually. Clinical significant improvement in effectiveness can be achieved by increasing its concentration. DOI: 10.5353/th_b5435643 Subjects: Denta

Book The Millennium Development Goals for Health

Download or read book The Millennium Development Goals for Health written by Adam Wagstaff and published by World Bank Publications. This book was released on 2004-01-01 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: Annotation Provides information on progress and trends, including poornonpoor disparities; health systems reform as a means of laying building blocks for the efficient and equitable delivery of effective interventions; the financing of health spending through domestic resources and aid; and improving the effectiveness of development assistance in health. Linking the health Millennium Development Goals? agenda with the broader poverty-reduction agenda, this book is a valuable resource for policymakers in developing countries and development practitioners working in the health, nutrition, and population sector as well as students and scholars of public health.