Download or read book Zhu Pang Pang Looks For Zhu Pang Pang written by Wilson Song and published by Lulu.com. This book was released on 2015-03-02 with total page 10 pages. Available in PDF, EPUB and Kindle. Book excerpt: Zhu Pang Pang can't find himself, what can he do to save himself? This is a story of how you can be healthier and choose the right things to eat.

Download or read book Farming With Sisters written by Jiu Shi and published by Funstory. This book was released on 2020-05-14 with total page 667 pages. Available in PDF, EPUB and Kindle. Book excerpt: My sister and sister are here to farm, and my sister is here to grow flax.

Download or read book Suddenly Carry Twins written by Hui WuGongDeXiaoHuLi and published by Funstory. This book was released on 2020-05-26 with total page 1072 pages. Available in PDF, EPUB and Kindle. Book excerpt: pang xia does not go to the bar to work to transfer some living expenses, who knows to be framed unexpectedly let a person do? What? Is pregnant? He's a man! What? Twins? What? Who's the father? Come on! Is he better than anyone who wants to know who that son of a bitch is? ! Mr. Li smiled. I didn't hear who you were talking about, son of a bitch. Pang Xia: I ... I was talking about Xu Jian. If it wasn't for him, how could that bastard have ended up like this?! Mr. Li nodded. "Xu Chen, do you know what to do now?" Xu Xiang bent down at ninety degrees. 'This is an oversized present called Pang Xia, already packaged with drunk wine. Please accept it with a smile, little uncle!' Mr. Li nodded his head in satisfaction. "Well done, I will reward you with the African projects. Hurry up and go!" Xu Jun was in the shape of a shooting star: Ya Yu Dian ~

Download or read book Operation Construction and Functionality of Direct Current Machines written by Amin, Muhammad and published by IGI Global. This book was released on 2015-04-30 with total page 419 pages. Available in PDF, EPUB and Kindle. Book excerpt: Direct current machines are a quickly evolving domain whose applications affect many aspects of modern life from computers and printers to toys, electric vehicles, and traction applications. As their many uses continue to grow, it has become apparent that understanding these machines is the key to understanding our future. Operation, Construction, and Functionality of Direct Current Machines brings together many concepts, from the most basic working principles and construction of DC machines to more advanced topics such as electro-magnetism, armature reaction, parallel operations, and many more. Highlighting theoretical concepts and numerical problems, this book is an essential reference source for students, educators, and anyone interested in the field of electric machines.

Download or read book A Case of Two Cities written by Qiu Xiaolong and published by Minotaur Books. This book was released on 2007-10-02 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt: At once a compelling crime novel and an insightful, moving portrayal of contemporary China, A Case of Two Cities is the finest novel yet in this critically-acclaimed, award-wining series. Inspector Chen Cao of the Shanghai Police Department is assigned a high-profile anti-corruption case, one in which the principal figure has long since fled to the United States and beyond the reach of the Chinese government. But Xing left behind his organization, and Chen, while assigned to root the co-conspirators, is not sure whether he's actually being set up to fail. In a twisting case that takes him from Shanghai all the way to the U.S., reuniting him with his colleague and counterpart from the U.S. Marshall's Service, Inspector Catherine Rhon, Chen finds himself at odds with hidden, powerful, and vicious enemies.

Download or read book An insight into the metabolism of New Psychoactive Substances written by Jakob Wallgren and published by Linköping University Electronic Press. This book was released on 2020-09-09 with total page 108 pages. Available in PDF, EPUB and Kindle. Book excerpt: New Psychoactive Substances (NPS) is an umbrella term covering hundreds of substances across different drug groups. Many of these substances were originally developed for therapeutic use but have later appeared on the recreational drug market. The use of NPS has been associated with many outbreaks leading to hospitalizations and has been implicated in numerous fatalities worldwide. To be able to analytically detect drugs in a forensic setting is vital in the fight against the abuse of NPS. One of the most notable challenges in detection of NPS is the identification of major urinary metabolites for use as biomarkers. Furthermore, given the lack of reference standards in most metabolism studies, the major urinary metabolites can often only be tentatively determined. This thesis describes the synthesis and analysis of potential metabolites used to identify the exact structures of major metabolites of the synthetic cannabinoid AKB-48, fentanyl and five fentanyl analogues in authentic human urine samples and/or hepatocyte incubations. Synthetic targets were chosen based on previous metabolism studies by our research group. Subsequently, synthetic routes were developed to produce numerous potential metabolites across the studied NPS. The synthesized reference standards were analyzed by LC-QTOF-MS alongside hepatocyte drug incubations and authentic human urine samples. Comparison of the resulting analytical data was used to determine the exact structures of many metabolites. This includes urinary metabolites of AKB-48 with a single hydroxyl group situated on a secondary carbon of the adamantane moiety, or position 3 or 5 of the pentyl side chain. For the studied fentanyls, the ?-OH and the 4’-OH metabolites were abundant metabolites identified in hepatocyte incubations while the 4’-OH, 4’-OH-3’-OMe and 3’,4’-diOH were the favored metabolic motifs among the metabolites identified in urine. Additionally, a concise synthetic route to produce synthetic cannabinoid metabolites with the 4-OH-5F pentyl side chain motif was developed and demonstrated for four synthetic cannabinoids. These findings and the developed synthetic routes can be used to provide forensic toxicology laboratories with urinary biomarkers for drug detection. Moreover, the synthesized reference standards of major metabolites can be studied to better understand the toxicity of their parent drugs. Nya psykoaktiva substanser (NPS) är det officiella namnet för den grupp droger som tidigare har kallats för designerdroger, nätdroger eller internetdroger. NPS definieras som droger som utgör ett likvärdigt hot mot folkhälsan som droger som återfinns på Förenta Nationernas narkotikakonventioner men som själva inte återfinns under dessa konventioner. Det finns hundratals olika rapporterade NPS spridda över olika droggrupper, såsom syntetiska cannabinoider och syntetiska opioider. Vissa av dessa droger syntetiserades ursprungligen i forskningssyfte, men tog sig senare in på den illegala drogmarknaden. De mer nyligen framtagna NPS är ofta designade att efterlikna effekterna av etablerade droger, såsom morfin eller ?9-THC, vilket är den huvudsakliga psykoaktiva substansen i cannabis. Användandet av NPS har associerats till många kluster av intoxikationer som har lett till hospitaliseringar. Många har även dött till följd av användandet av NPS. Inte minst i USA där en grupp av NPS kallad för fentanylanaloger är högst delaktig i den pågående opioidkrisen. Den ständiga inströmningen av nya NPS leder till att detektion av och diskriminering mellan dem utgör en svår utmaning för forensiska toxikologilaboratorier. Tillgången av lämpliga referenssubstanser möter inte deras efterfrågan, delvis på grund av att vilka biomarkörer som är optimala för drogdetektion inte alltid är uppenbart. Till exempel så är metabolismen av syntetiska cannabinoider i regel både snabb och omfattande. Av den anledningen kan användandet av modersubstansen som biomarkör vid analys av urin leda till falskt negativa resultat. Urin som biologisk matris har många fördelar jämfört med blod. Till exempel så har urin ett längre detektionsfönster och högre drogkoncentrationer. För att kunna identifiera optimala biomarkörer för droganalys av urinprover så måste drogernas metabolism utredas. De flesta metabolismstudier använder sig av humana levermikrosomer eller hepatocyter som inkuberas tillsammans med droger för att generera metaboliter in vitro. Urinprover från individer i vilkas blod det har återfunnits droger används också men tillgången är tyvärr begränsad. Dessa metaboliter separeras sedan med hjälp av kromatografiska tekniker och deras kemiska strukturer bestäms med hjälp av masspektrometri. Dock så är utvärderingen av masspektrometridata komplicerad och det är heller inte möjligt att skilja på vissa positionsisomerer genom att enbart analysera masspektrometridata. För att kunna möjliggöra exakt strukturutredning så krävs referensstandarder. Därför var målet med denna avhandling att addera syntes och analys av referensstandarder till de etablerade tillvägagångssätten att studera metabolismen av NPS. Ett stort antal potentiella metaboliter av AKB-48 och andra syntetiska cannabinoider samt av fentanyl och fentanylanaloger syntetiserades. Genom att använda dessa referensstandarder i metabolismstudier så kunde de exakta kemiska strukturerna för många metaboliter bestämmas. Dessutom så identifierades mönster i de metaboliska profilerna bland fentanyl och fentanylanaloger. Dessa mönster kan användas för att förbättra predikteringen av metaboliter för andra nuvarande och kommande fentanylanaloger. Dessa resultat samt de utvecklade syntesvägarna kan nyttjas i framställningen av referenssubstanser i syfte att användas som biomarkörer för att i urin kunna detektera drogmissbruk. Referenssubstanserna kan även användas för att studera metaboliternas farmakologiska egenskaper vilket kan leda till en djupare förståelse kring toxiciteten hos modersubstanserna.

Download or read book Target Receptors in the Control of Insect Pests Part II written by and published by Elsevier. This book was released on 2014-04-15 with total page 550 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume of Advances in Insect Physiology contains comprehensive interdisciplinary reviews on basic and practical aspects relevant to major target receptors for crucial physiological functions and mechanisms in prokaryotic and eukaryotic organisms, particularly insects. Chapters emphasize advanced genomic, molecular biology, chemical, and proteomic research on the receptors and their corresponding agonist and antagonist ligands. The book encompasses target systems such as sodium channels, octopamine/tyramine receptors, ABC transporters, acetylcholinesterase as a target enzyme, juvenile hormone receptors, and receptors targeted by neuropeptides. - Contains important, comprehensive and in-depth reviews - An essential reference source for invertebrate physiologists and neurobiologists, entomologists, zoologists, and insect biochemists - First published in 1963, this serial is ranked second in the highly competitive ISI category of Entomology

Download or read book Urban Construction and Management Engineering IV written by Seyed Mohammadreza Ghadiri and published by CRC Press. This book was released on 2024-03-07 with total page 1124 pages. Available in PDF, EPUB and Kindle. Book excerpt: Urban Construction and Management Engineering IV focuses on the research of construction technology and the engineering management in urban construction. This proceedings gathers the most cutting-edge research and achievements, and will provide scholars and engineers with preferable research directions and engineering solutions as reference. Subjects in this proceedings include: Civil Engineering Engineering Structure Engineering Management Low Carbon City Urban Management The works of this proceedings encourages development of civil engineering and construction technology. Thereby, the work promotes scientific information interchange between scholars from the top universities, research centers and high-tech enterprises working all around the world.

Download or read book JingGuo Novel Broken Jar Broken Fall written by Jing Guo and published by Jing Guo. This book was released on with total page 1038 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Love We Want written by Yi ZhiZhiLvLuo and published by Funstory. This book was released on 2020-09-12 with total page 835 pages. Available in PDF, EPUB and Kindle. Book excerpt: Love is far away, love is near, it has come, are you there? This was the story of Gu Yu and An An. It was also the story of courage, such as bravely forgetting, bravely accepting, bravely bearing ...

Download or read book The Classic of Changes written by and published by Columbia University Press. This book was released on 2004-03-31 with total page 621 pages. Available in PDF, EPUB and Kindle. Book excerpt: Used in China as a book of divination and source of wisdom for more than three thousand years, the I Ching has been taken up by millions of English-language speakers in the nineteenth century. The first translation ever to appear in English that includes one of the major Chinese philosophical commentaries, the Columbia I Ching presents the classic book of changes for the world today. Richard Lynn's introduction to this new translation explains the organization of The Classic of Changes through the history of its various parts, and describes how the text was and still is used as a manual of divination with both the stalk and coin methods. For the fortune-telling novice, he provides a chart of trigrams and hexagrams; an index of terms, names, and concepts; and a glossary and bibliography. Lynn presents for the first time in English the fascinating commentary on the I Ching written by Wang Bi (226-249), who was the main interpreter of the work for some seven hundred years. Wang Bi interpreted the I Ching as a book of moral and political wisdom, arguing that the text should not be read literally, but rather as an expression of abstract ideas. Lynn places Wang Bi's commentary in historical context.

Download or read book Heijin written by Ko-Lin Chin and published by Routledge. This book was released on 2016-07-08 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work examines the structure and illegal activities of organized crime groups in Taiwan and explores the infiltration of crime groups into the business and political arenas. It looks at the intricate relationship among government officials, elected deputies, businessmen, and underworld figures.

Download or read book Regulating Gut Microbiota by Lactic Acid Bacteria Effects Based on Probiotic Characteristics and Their Metabolites written by Dan Zhao and published by Frontiers Media SA. This book was released on 2024-09-05 with total page 279 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lactic acid bacteria are a type of important probiotic that may be found in a wide range of nutrient-rich habitats, including food, feed, soil, and organisms like animals as well as plants. According to the U.S. Food and Drug Administration, many species of lactic acid bacteria and their metabolites are “generally regarded as safe (GRAS)”. The most commonly used strains as probiotics spread in genera Lactobacilli, Bifidobacterium, Lactococcus, Enterococcus, and Streptococcus. They have been shown to enhance intestinal transit, balance gut microbiota, and preserve the colon's acid-base equilibrium, which regulates the immune system and lowers serum cholesterol levels.

Download or read book Global Film Color written by Sarah Street and published by Rutgers University Press. This book was released on 2024-05-17 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: Global Film Color: The Monopack Revolution at Midcentury explores color filmmaking in a variety of countries and regions including India, China, Japan, and Russia, and across Europe and Africa. Most previous accounts of color film have concentrated on early 20th century color processes and Technicolor. Far less is known about the introduction and application of color technologies in the period from the mid-1940s to the 1980s, when photochemical, “monopack” color stocks came to dominate global film markets. As Eastmancolor, Agfacolor, Fujicolor and other film stocks became broadly available and affordable, national film industries increasingly converted to color, transforming the look and feel of global cinema. Covering a broad range of perspectives, the chapters explore themes such as transnational flows, knowledge exchange and transfer, the cyclical and asymmetrical circulation of technology in a global context, as well as the accompanying transformation of color film aesthetics in the postwar decades.

Download or read book Evil Master written by Qian YunYuFeng and published by Funstory. This book was released on 2020-02-23 with total page 747 pages. Available in PDF, EPUB and Kindle. Book excerpt: Duan Hong, a man with a demonic personality, was sent to the temple to practice martial arts. The Violent Spirit hidden in his blood allowed him to burst forth with unparalleled strength. As the saying goes, "color is emptiness," "void is color." The Buddha sat inside, and the wine and sex passed through his intestines. When he returned to the city, he still found it difficult to change his devilish nature. Dual-faced beautiful mature woman, the beautiful mature woman, the beautiful Barbarian Queen Sister walked around him, and a pair of pure and innocent sisters were by his side as well. He, who was surrounded by red powder, how would he perform his devilish life ...

Download or read book Advanced Optimization for Motion Control Systems written by Jun Ma and published by CRC Press. This book was released on 2020-01-24 with total page 183 pages. Available in PDF, EPUB and Kindle. Book excerpt: Precision motion control is strongly required in many fields, such as precision engineering, micromanufacturing, biotechnology, and nanotechnology. Although great achievements have been made in control engineering, it is still challenging to fulfill the desired performance for precision motion control systems. Substantial works have been presented to reveal an increasing trend to apply optimization approaches in precision engineering to obtain the control system parameters. In this book, we present a result of several years of work in the area of advanced optimization for motion control systems. The book is organized into two parts: Part I focuses on the model-based approaches, and Part II presents the data-based approaches. To illustrate the practical appeal of the proposed optimization techniques, theoretical results are verified with practical examples in each chapter. Industrial problems explored in the book are formulated systematically with necessary analysis of the control system synthesis. By virtue of the design and implementation nature, this book can be used as a reference for engineers, researchers, and students who want to utilize control theories to solve the practical control problems. As the methodologies have extensive applicability in many control engineering problems, the research results in the field of optimization can be applied to full-fledged industrial processes, filling in the gap between research and application to achieve a technology frontier increment.

Download or read book Coronavirus Disease COVID 19 written by Nima Rezaei and published by Springer Nature. This book was released on 2021-05-10 with total page 964 pages. Available in PDF, EPUB and Kindle. Book excerpt: In December 2019, the world witnessed the occurrence of a new coronavirus to humanity. The disease spread quickly and became known as a pandemic globally, affecting both society and the health care system, both the elderly and young groups of people, and both the men’s and women’s groups. It was a universal challenge that immediately caused a surge in scientific research. Be a part of a world rising in fighting against the pandemic, the Coronavirus Disease - COVID-19 was depicted in the early days of the pandemic, but updated by more than 200 scientists and clinicians to include many facets of this new infectious pandemic, including i, characteristics, ecology, and evolution of coronaviruses; ii, epidemiology, genetics, and pathogenesis (immune responses and oxidative stress) of the disease; iii, diagnosis, prognosis, and clinical manifestations of the disease in pediatrics, geriatrics, pregnant women, and neonates; iv, challenges of co-occurring the disease with tropical infections, cardiovascular diseases, hypertension, and cancer and to the settings of dentistry, hematology, ophthalmology, and pharmacy; v, transmission, prevention, and potential treatments, ranging from supportive ventilator support and nutrition therapy to potential virus- and host-based therapies, immune-based therapies, photobiomodulation, antiviral photodynamic therapy, and vaccines; vi, the resulting consequences on social lives, mental health, education, tourism industry and economy; and vii, multimodal approaches to solve the problem by bioinformatic methods, innovation and ingenuity, globalization, social and scientific networking, interdisciplinary approaches, and art integration. We are approaching December 2020 and the still presence of COVID-19, asking us to call it COVID (without 19).