Download or read book NGF and Related Molecules in Health and Disease written by L. Aloe and published by Elsevier. This book was released on 2003-12-10 with total page 563 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book highlights different aspects of current understanding of neurotrophin-receptor signal transduction pathways, including the signaling endosome hypothesis. Findings on the synaptotrophic potential of NGF and related neurotrophins, neurotrophin involvement in neuronal stem cell biology, biological activity of the NGF precursor proNGF, and nociception- and antinociception-associated activity of NGF and/or BDNF are also presented and discussed. Several chapters deal with the involvement of various neurotrophins in the control of different nonneuronal processes, such as immune, inflammatory and allergic reactions, tissue repair and wound healing. The findings showed that neurotrophins play important roles in the pathobiology of a surprising variety of seemingly unrelated non-neurological diseases, including bronchial asthma, rheumatoid arthritis, systemic sclerosis, hair growth disorders, psoriasis, corneal and skin ulcers, atherosclerosis, metabolic syndrome, crush syndrome, and Behçet's disease. There are also chapters on the involvement of NGF and related molecules in neurological diseases, including Huntington's disease, the multiple sclerosis-like model of experimental allergic encephalomyelitis, peripheral neuropathies, neuroblastoma, Parkinson's disease, Alzheimer's disease, and even motion sickness syndrome, also psychiatric disorders, including depression and schizophrenia. Finally, potential important therapeutic benefits are presented, for diabetic neuropathy, gastrointestinal dysmotility, CNS neurodegenerative disease, spinal cord injuries, cutaneous and corneal ulcers, as well as peripheral ischemic vasculopathy.

Download or read book Recent Advances in NGF and Related Molecules written by Laura Calzà and published by Springer Nature. This book was released on 2021-08-27 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: More than fifty years after its initial discovery by Rita Levi Montalcini and Stanley Cohen and the proposal of the neurotrophic theory, nerve growth factor (NGF) has become the prototype of a family of biologically active molecules called neurotrophic factors (NTFs). This book addresses important advances in NTF research, from basic science to clinical medicine. It focuses mainly on NGF, but also includes individual chapters dealing with the brain-derived neurotrophic factor (BDNF) and ligands of the glial cell line-derived neurotrophic factor (GDNF) family, which have attracted increasing interest in the neuroscience community because of their diverse effects in the normal and diseased brain. In the first part of the book, the authors provide the necessary background for the following chapters and discuss the basic mechanisms and pathways of NGF signal transduction. In the following sections, they then examine the regenerative activity and neuroprotective capacity of NGF during development and in normal and diseased tissues in adulthood and discuss the role of NGF in Alzheimer's disease and nociception. In addition, the role of NGF in processing sensory information and its influence on behavior is further discussed. The book concludes with an overview of the diagnostic and therapeutic potential of NTF in psychiatric disorders and obesity management, as well as a highlight of NGF research in veterinary medicine. Many of the authors of this volume participated in the Second International Rita Levi-Montalcini Meeting, held in Bologna, Italy, in 2019. The book covers a wide range of important topics in past and current NTF research and will appeal to basic researchers and clinicians alike.

Download or read book Life Itself written by Boyce Rensberger and published by Oxford University Press, USA. This book was released on 1996 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: In Amazing Life, Boyce Rensberger takes readers to the frontlines of cell research with some of the brightest investigators in molecular, cellular, and developmental biology. The hottest topics in biomedical research are covered.

Download or read book Brain Repair written by Donald G. Stein and published by Oxford University Press, USA. This book was released on 1997 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over a half million people each year suffer brain-damaging injuries and diseases--but the outlook for their eventual recovery is far more hopeful than it was just a short while ago. In Brain Repair, three internationally renowned neuroscientists team up to offer an intriguing and up-to-the-minute introduction to the explosive advances being made in the research, technology, and treatment of brain damage. The key to neuroscience's most exciting discoveries to date is a theory that is rapidly gaining adherents in the scientific community--the theory of neuroplasticity. Neuroplasticity stresses that cells throughout the brain can not only regenerate, but can adapt their function to assume critical roles once performed by damaged tissue. In clear, accessible language, the authors show us that the brain manufactures a host of complex chemicals that actually foster growth in damaged brain cells. We visit the laboratories where researchers are untangling the mystery of Parkinson's disease and trying to understand what goes wrong in stroke victims, and why some, thought permanently impaired, show remarkable improvements. In addition, they discuss how even today misguided ideas can adversely affect how physicians treat patients. And, along the way, they detail the fascinating history of how brain structure and functioning has been understood and studied, from prehistoric times to the present. A best-selling volume in France and Mexico, Brain Repair provides a vividly written, wide-ranging look at the leading edge of one of science's most exciting frontiers.

Download or read book Cumulated Index Medicus written by and published by . This book was released on 2000 with total page 1764 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Decoding Darkness written by Rudolph E Tanzi and published by Basic Books. This book was released on 2008-01-07 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: Working from the intriguing hypothesis that Alzheimer's dementia is the result of a renegade protein-beta amyloid-Tanzi and others set out to find the gene responsible for its production. Decoding Darkness takes us deep into the minds and far-flung labs of many a prominent researcher, offering an intimate view of the high stakes of molecular genetics, the revolution that propels it, the obstacles that threaten to derail it, and the families whose lives are so dependent upon it. Tanzi and Parson ultimately reveal that Alzheimer's, like heart disease, may be effectively treated-even prevented.

Download or read book Egyptian Mystics written by Moustafa Gadalla and published by Moustafa Gadalla. This book was released on 2016-12-02 with total page 147 pages. Available in PDF, EPUB and Kindle. Book excerpt: Egyptian alchemy and Sufism, with a coherent explanation of fundamentals and practices. This book explains how Ancient Egypt is the origin of alchemy and present-day Sufism, and how the mystics of Egypt camouflage their practices with a thin layer of Islam. The book also explains the progression of the mystical Way towards enlightenment, with a coherent explanation of its fundamentals and practices. It shows the correspondence between the Ancient Egyptian calendar of events and the cosmic cycles of the universe. This Expanded Edition of the book is divided into four parts containing a total of 13 chapters and five appendices. Part I: The Hidden Treasure consists of two chapters: Chapter 1: Egyptian Mysticism and Islamized Sufism will cover the differences between dogmatic and mystical routes and how ancient Egypt is the source of Sufism and alchemy. Chapter 2: The Treasure Within will cover the limitations of humans' organ of perceptions and how to find realities with such limitations. Part II: Transformation From Dust To Gold consists of five chapters—3 through 7: Chapter 3: The Alchemist Way will cover the source of alchemy as being Ancient Egypt; and the progression along the alchemist way; and the role of a guide in the process. Chapter 4: The Purification Process will cover both outer and inner purifications through the process of living in the world. Chapter 5: Basic Practices will cover general practices by the Egyptian mystics to increase their awareness of the real world. Chapter 6: The Way to Revelations will cover the methods by which a mystical aspirant can find knowledge through revelations. Chapter 7: The Heavenly Helpers will cover the role and duty of those who attained super natural powers, to help others on earth. Part III: The Public Visitation Fairs has four chapters—chapters 8 through 11: Chapter 8: The Cyclical Renewal Festivals will cover the importance of holding and participating in annual festivals. Chapter 9: Samples of Ancient-Present Festivals will cover about a dozen annual ancient egyptian festivals and how many of them are very familiar and being observed throughout the western world. Chapter 10: The Egyptian Spirited Fairs (Mouleds) will cover the main elements of a typical festival Chapter 11: Egyptian Themes of Saint's Nick Traditional Festivities will cover a comparison between the commonly known Saint Nick's Christmas traditions with a typical Ancient Egyptian festival of a folk-saint. Part IV: Come One Come All has two chapters—12 through 13. Chapter 12: Fellowship Formations covers the general structure and practices to form/participate in a mystical fellowship. Chapter 13: Auset (Isis)—The Model Philosopher covers the principles and practices of Sufism as found in the Ancient Egyptian allegory of Isis and Osiris. The contents of the five appendices are self evident from each's title, as follows: Appendix A: Miscellaneous Sufi Terms and Their Ancient Egyptian Roots Appendix B: Sleeping With the Enemy (Surviving Islam) Appendix C: Zikr—The Ecstatic Practice Appendix D: Reaching the Hearts and Minds (Effective Communication) Appendix E: The Egyptian vs. The Latin Calendar.

Download or read book Index Medicus written by and published by . This book was released on 2004 with total page 1812 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book International Review of Cytology written by and published by Academic Press. This book was released on 1999-04-19 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: International Review of Cytology presents current advances and comprehensive reviews in cell biology-both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research. Key Features * Differentiation-Related Changes in the Cell Cycle * Nitric Oxide and Endothelin-1 in Coronary and Pulmonary Circulation * Phosphoinositide Kinases in Higher Plant Cells * Chlamydomonas Cell Cycle Mutants * Cellular Aspects of Trophic Actions in the Nervous System * Conformational Changes of Muscle Contractile Proteins

Download or read book The Big Book of Quotes written by M. Prefontaine and published by Createspace Independent Publishing Platform. This book was released on 2015-10-19 with total page 442 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Big Book of Quotes is a collection of over 3,500 quotations from some of the greatest minds that ever existed. This is a book which you can just pick up anytime and carry on where you left off last time. It is for those who want to pep up a speech, a presentation or an email and for those who just want to jump start their brains with thought provoking or amusing quotations. The essence of the best quotes are that they express a truth or an insight in a short and often amusing way. Thoughts expressed succinctly have tremendous power. They can inspire and motivate, they can get a message across and they can provide insight. I hope this book will prove useful, amusing and the quotes will resonate with you.

Download or read book Called to Lead written by Anthony B. Robinson and published by Wm. B. Eerdmans Publishing. This book was released on 2012-07-20 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: Following up on their previous volume, Called to Be Church: The Book of Acts for a New Day, biblical scholar Robert Wall and pastoral leader Anthony Robinson here join forces again. Featuring both exegetical study and dynamic contemporary exposition, each chapter of Called to Lead first interprets the text of 1 and 2 Timothy as Scripture and then engages 1 and 2 Timothy for today's church leaders. The book covers many vexing issues faced by church leaders then and now -- such issues as the use of money, leadership succession, pastoral authority, and the role of Scripture. Through it all, Called to Lead shows how Timothy remains a text of great value for the church today

Download or read book Artificial Intelligence Applications and Innovations written by Ilias Maglogiannis and published by Springer Nature. This book was released on 2020-05-29 with total page 475 pages. Available in PDF, EPUB and Kindle. Book excerpt: This 2 volume-set of IFIP AICT 583 and 584 constitutes the refereed proceedings of the 16th IFIP WG 12.5 International Conference on Artificial Intelligence Applications and Innovations, AIAI 2020, held in Neos Marmaras, Greece, in June 2020.* The 70 full papers and 5 short papers presented were carefully reviewed and selected from 149 submissions. They cover a broad range of topics related to technical, legal, and ethical aspects of artificial intelligence systems and their applications and are organized in the following sections: Part I: classification; clustering - unsupervised learning -analytics; image processing; learning algorithms; neural network modeling; object tracking - object detection systems; ontologies - AI; and sentiment analysis - recommender systems. Part II: AI ethics - law; AI constraints; deep learning - LSTM; fuzzy algebra - fuzzy systems; machine learning; medical - health systems; and natural language. *The conference was held virtually due to the COVID-19 pandemic.

Download or read book From Anxiety to Love written by Corinne Zupko and published by New World Library. This book was released on 2018-01-18 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: Get Ready for Unstoppable Inner Peace Author Corinne Zupko undertook her study of psychology out of necessity when debilitating anxiety threatened to derail her life. Seeking ways to do more than temporarily alleviate her symptoms, Corinne began to study A Course in Miracles (ACIM), mindfulness meditation, and the latest therapeutic approaches for treating anxiety. In From Anxiety to Love, she shares what she learned and gently guides you through the process, helping you undo anxiety-based thinking and fostering mindful shifts in your thoughts and actions. Whether struggling with everyday stress or near-crippling discomfort, you will find that Corinne’s approach offers a new way of healing from — rather than just coping with — fear and anxiety.

Download or read book Essentials of Interventional Techniques in Managing Chronic Pain written by Laxmaiah Manchikanti and published by Springer. This book was released on 2018-01-04 with total page 711 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive review covers the full and latest array of interventional techniques for managing chronic pain. Chapters are grouped by specific treatment modalities that include spinal interventional techniques, nonspinal and peripheral nerve blocks, sympathetic interventional techniques, soft tissue and joint injections, and implantables. Practical step-by-step and evidence-based guidance is given to each approach in order to improve the clinician's understanding. Innovative and timely, Essentials of Interventional Techniques in Managing Chronic Pain is a critical resource for anesthesiologists, neurologists, and rehabilitation and pain physicians.

Download or read book Panminerva Medica written by and published by . This book was released on 1990 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Herbal Medicine written by Iris F. F. Benzie and published by CRC Press. This book was released on 2011-03-28 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: The global popularity of herbal supplements and the promise they hold in treating various disease states has caused an unprecedented interest in understanding the molecular basis of the biological activity of traditional remedies. Herbal Medicine: Biomolecular and Clinical Aspects focuses on presenting current scientific evidence of biomolecular ef

Download or read book Psychoneuroimmunology written by Manfred Schedlowski and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 590 pages. Available in PDF, EPUB and Kindle. Book excerpt: Psychoneuroimmunology is the first textbook to examine the complex functional relationships between the nervous system, the neuroendocrine and the immune system. The international leaders in this field have been brought together to create this pioneering text; each contributing from their area of expertise. The result is a comprehensive yet accessible interdisciplinary introduction to psychoneuroimmunology which also takes you further than the foundations of those fascinating topics by covering the most recent research in HIV/AIDS, autoimmune diseases, and the reactivation of latent herpes viruses. Attention is also given to the effects of behavior such as physical exercise, sleep, acute and chronic stress, and conditioning of immune functions in animals and humans. The whole is brought together with a wealth of cited research studies, and over 200 illustrations.