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Book Wireless Multichannel Microsystems for Time Share Chemical and Electrical Neural Recording

Download or read book Wireless Multichannel Microsystems for Time Share Chemical and Electrical Neural Recording written by Masoud Roham and published by . This book was released on 2010 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt: This project has developed single-chip wireless microsystems fabricated using a 0.5-μm double-poly triple-metal n-well CMOS process that incorporate three powerful neuromonitoring techniques: fast-scan cyclic voltammetry (FSCV) for monitoring neurotransmitter concentrations, extracellular electrophysiology for single-unit recording, and time-share recordings of these two techniques for quasi-simultaneous measurements of chemical and electrical neural activity at a single brain site in vivo. These devices also support electrical stimulation for focal activation of neural circuits. In particular, a 1.1-mW, 5-mm2, 4-channel integrated circuit has been developed that can be dynamically configured to perform neurochemical monitoring using 300-V/s FSCV and neuroelectrical recording using extracellular electrophysiology. The chip architecture uses a 76-μW, 3rd-order, continuous-time delta-sigma modulator per channel that achieves an rms input-referred noise of 56.7 pA (dc-5 kHz) and 3.5 μV (1.1-5 kHz) for chemical and electrical neuromonitoring, respectively. The chip architecture also incorporates monolithic circuitry for generating FSCV and biphasic constant-current stimulus waveforms. It has been externally interfaced with carbon-fiber microelectrodes implanted acutely in the caudate-putamen of an anesthetized rat, and enables chemically resolved monitoring of electrically evoked dopamine release and its postsynaptic bioelectrical response at the same recording site. The dopamine limit of detection corresponding to a signal-to-rms noise ratio of three is estimated to be 16.7 nM, which compares favorably with the amplitude of phasic dopamine transients that varies in the range of 40 nM-1 μM. The chip has also been packaged on a miniature rigid-flex substrate to develop an implantable device for investigating brain-behavior relationships in an ambulatory rat. The device successfully captures the effect of high-dose amphetamine administration on electrically and non-electrically evoked dopamine neurotransmission in the brain, demonstrating that the technology developed throughout the course of this project can indeed be applied to conduct neurochemical measurements in the context of behavior.

Book Integrated Microsystems

    Book Details:
  • Author : Krzysztof Iniewski
  • Publisher : CRC Press
  • Release : 2017-12-19
  • ISBN : 1439836213
  • Pages : 760 pages

Download or read book Integrated Microsystems written by Krzysztof Iniewski and published by CRC Press. This book was released on 2017-12-19 with total page 760 pages. Available in PDF, EPUB and Kindle. Book excerpt: As rapid technological developments occur in electronics, photonics, mechanics, chemistry, and biology, the demand for portable, lightweight integrated microsystems is relentless. These devices are getting exponentially smaller, increasingly used in everything from video games, hearing aids, and pacemakers to more intricate biomedical engineering and military applications. Edited by Kris Iniewski, a revolutionary in the field of advanced semiconductor materials, Integrated Microsystems: Electronics, Photonics, and Biotechnology focuses on techniques for optimized design and fabrication of these intelligent miniaturized devices and systems. Composed of contributions from experts in academia and industry around the world, this reference covers processes compatible with CMOS integrated circuits, which combine computation, communications, sensing, and actuation capabilities. Light on math and physics, with a greater emphasis on microsystem design and configuration and electrical engineering, this book is organized in three sections—Microelectronics and Biosystems, Photonics and Imaging, and Biotechnology and MEMs. It addresses key topics, including physical and chemical sensing, imaging, smart actuation, and data fusion and management. Using tables, figures, and equations to help illustrate concepts, contributors examine and explain the potential of emerging applications for areas including biology, nanotechnology, micro-electromechanical systems (MEMS), microfluidics, and photonics.

Book Single chip Wireless Microsystems for Multichannel Neural Biopotential Recording

Download or read book Single chip Wireless Microsystems for Multichannel Neural Biopotential Recording written by Pedram Mohseni and published by . This book was released on 2005 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book A Wireless Microsystem for Multichannel Neural Recording Microprobes

Download or read book A Wireless Microsystem for Multichannel Neural Recording Microprobes written by Hao Yu and published by . This book was released on 2004 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Implantable Biomedical Microsystems

Download or read book Implantable Biomedical Microsystems written by Swarup Bhunia and published by Elsevier. This book was released on 2015-01-28 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research and innovation in areas such as circuits, microsystems, packaging, biocompatibility, miniaturization, power supplies, remote control, reliability, and lifespan are leading to a rapid increase in the range of devices and corresponding applications in the field of wearable and implantable biomedical microsystems, which are used for monitoring, diagnosing, and controlling the health conditions of the human body. This book provides comprehensive coverage of the fundamental design principles and validation for implantable microsystems, as well as several major application areas. Each component in an implantable device is described in details, and major case studies demonstrate how these systems can be optimized for specific design objectives. The case studies include applications of implantable neural signal processors, brain-machine interface (BMI) systems intended for both data recording and treatment, neural prosthesis, bladder pressure monitoring for treating urinary incontinence, implantable imaging devices for early detection and diagnosis of diseases as well as electrical conduction block of peripheral nerve for chronic pain management. Implantable Biomedical Microsystems is the first comprehensive coverage of bioimplantable system design providing an invaluable information source for researchers in Biomedical, Electrical, Computer, Systems, and Mechanical Engineering as well as engineers involved in design and development of wearable and implantable bioelectronic devices and, more generally, teams working on low-power microsystems and their corresponding wireless energy and data links. First time comprehensive coverage of system-level and component-level design and engineering aspects for implantable microsystems. Provides insight into a wide range of proven applications and application specific design trade-offs of bioimplantable systems, including several major case studies Enables Engineers involved in development of implantable electronic systems to optimize applications for specific design objectives.

Book Neural Interface Engineering

Download or read book Neural Interface Engineering written by Liang Guo and published by Springer Nature. This book was released on 2020-05-04 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive reference to major neural interfacing technologies used to transmit signals between the physical world and the nervous system for repairing, restoring and even augmenting body functions. The authors discuss the classic approaches for neural interfacing, the major challenges encountered, and recent, emerging techniques to mitigate these challenges for better chronic performances. Readers will benefit from this book’s unprecedented scope and depth of coverage on the technology of neural interfaces, the most critical component in any type of neural prostheses. Provides comprehensive coverage of major neural interfacing technologies; Reviews and discusses both classic and latest, emerging topics; Includes classification of technologies to provide an easy grasp of research and trends in the field.

Book Electrochemical Methods for Neuroscience

Download or read book Electrochemical Methods for Neuroscience written by Adrian C. Michael and published by CRC Press. This book was released on 2006-12-13 with total page 540 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the first implant of a carbon microelectrode in a rat 35 years ago, there have been substantial advances in the sensitivity, selectivity and temporal resolution of electrochemical techniques. Today, these methods provide neurochemical information that is not accessible by other means. The growing recognition of the versatility of electrochemi

Book VLSI Circuits for Biomedical Applications

Download or read book VLSI Circuits for Biomedical Applications written by Krzysztof Iniewski and published by Artech House. This book was released on 2008 with total page 453 pages. Available in PDF, EPUB and Kindle. Book excerpt: Supported with over 280 illustrations and over 160 equations, the book offers cutting-edge guidance on designing integrated circuits for wireless biosensing, body implants, biosensing interfaces, and molecular biology. You discover innovative design techniques and novel materials to help you achieve higher levels circuit and system performance.

Book Integrated Microsystems

    Book Details:
  • Author : Krzysztof Iniewski
  • Publisher : CRC Press
  • Release : 2011-10-11
  • ISBN : 1439836205
  • Pages : 762 pages

Download or read book Integrated Microsystems written by Krzysztof Iniewski and published by CRC Press. This book was released on 2011-10-11 with total page 762 pages. Available in PDF, EPUB and Kindle. Book excerpt: As rapid technological developments occur in electronics, photonics, mechanics, chemistry, and biology, the demand for portable, lightweight integrated microsystems is relentless. These devices are getting exponentially smaller, increasingly used in everything from video games, hearing aids, and pacemakers to more intricate biomedical engineering and military applications. Edited by Kris Iniewski, a revolutionary in the field of advanced semiconductor materials, Integrated Microsystems: Electronics, Photonics, and Biotechnology focuses on techniques for optimized design and fabrication of these intelligent miniaturized devices and systems. Composed of contributions from experts in academia and industry around the world, this reference covers processes compatible with CMOS integrated circuits, which combine computation, communications, sensing, and actuation capabilities. Light on math and physics, with a greater emphasis on microsystem design and configuration and electrical engineering, this book is organized in three sections—Microelectronics and Biosystems, Photonics and Imaging, and Biotechnology and MEMs. It addresses key topics, including physical and chemical sensing, imaging, smart actuation, and data fusion and management. Using tables, figures, and equations to help illustrate concepts, contributors examine and explain the potential of emerging applications for areas including biology, nanotechnology, micro-electromechanical systems (MEMS), microfluidics, and photonics.

Book Neural Microelectrodes  Design and Applications

Download or read book Neural Microelectrodes Design and Applications written by Stuart Cogan and published by . This book was released on 2019 with total page 1 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neural electrodes enable the recording and stimulation of bioelectrical activity in the nervous system. This technology provides neuroscientists with the means to probe the functionality of neural circuitry in both health and disease. In addition, neural electrodes can deliver therapeutic stimulation for the relief of debilitating symptoms associated with neurological disorders such as Parkinson's disease and may serve as the basis for the restoration of sensory perception through peripheral nerve and brain regions after disease or injury. Lastly, microscale neural electrodes recording signals associated with volitional movement in paralyzed individuals can be decoded for controlling external devices and prosthetic limbs or driving the stimulation of paralyzed muscles for functional movements. In spite of the promise of neural electrodes for a range of applications, chronic performance remains a goal for long-term basic science studies, as well as clinical applications. New perspectives and opportunities from fields including tissue biomechanics, materials science, and biological mechanisms of inflammation and neurodegeneration are critical to advances in neural electrode technology. This Special Issue will address the state-of-the-art knowledge and emerging opportunities for the development and demonstration of advanced neural electrodes.

Book Smart Sensors for Health and Environment Monitoring

Download or read book Smart Sensors for Health and Environment Monitoring written by Chong-Min Kyung and published by Springer. This book was released on 2015-07-22 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers two most important applications of smart sensors, namely bio-health sensing and environmental monitoring. The approach taken is holistic and covers the complete scope of the subject matter from the principles of the sensing mechanism, through device physics, circuit and system implementation techniques, and energy issues to wireless connectivity solutions. It is written at a level suitable mainly for post-graduate level researchers interested in practical applications. The chapters are independent but complementary to each other, and the book works within the wider perspective of essential smart sensors for the Internet of Things (IoT). This is the second of three books based on the Integrated Smart Sensors research project, which describe the development of innovative devices, circuits, and system-level enabling technologies. The aim of the project was to develop common platforms on which various devices and sensors can be loaded, and to create systems offering significant improvements in information processing speed, energy usage, and size. This book contains substantial reference lists and over 150 figures, introducing the reader to the subject in a tutorial style whilst also addressing state-of-the-art research results, allowing it to be used as a guide for starting researchers.

Book Advances in Network Electrophysiology

Download or read book Advances in Network Electrophysiology written by Makoto Taketani and published by Springer Science & Business Media. This book was released on 2006-11-22 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Network Electrophysiology: Using Multi Electrode Arrays explores methods for using electrophysiological techniques for monitoring the concurrent activity of ensembles of single neurons. It reviews the recent progress in both electronics and computational tools developed to analyze the functional operations of large ensembles of neurons using multi-electrode arrays and in vitro preparations. In addition, it gives readers a sense of the applications made possible by these technological tools. This volume is the reference for researchers, industry, graduate students, and postdoctoral fellows in all areas of neuroscience, cognitive neuroscience, pharmaceutical science, and bioengineering.

Book Inorganic Nanoparticles

Download or read book Inorganic Nanoparticles written by Claudia Altavilla and published by CRC Press. This book was released on 2017-12-19 with total page 885 pages. Available in PDF, EPUB and Kindle. Book excerpt: Among the various nanomaterials, inorganic nanoparticles are extremely important in modern technologies. They can be easily and cheaply synthesized and mass produced, and for this reason, they can also be more readily integrated into applications. Inorganic Nanoparticles: Synthesis, Applications, and Perspectives presents an overview of these special materials and explores the myriad ways in which they are used. It addresses a wide range of topics, including: Application of nanoparticles in magnetic storage media Use of metal and oxide nanoparticles to improve performance of oxide thin films as conducting media in commercial gas and vapor sensors Advances in semiconductors for light-emitting devices and other areas related to the energy sector, such as solar energy and energy storage devices (fuel cells, rechargeable batteries, etc.) The expanding role of nanosized particles in the field of catalysis, art conservation, and biomedicine The book’s contributors address the growing global interest in the application of inorganic nanoparticles in various technological sectors. Discussing advances in materials, device fabrication, and large-scale production—all of which are urgently required to reduce global energy demands—they cover innovations in areas such as solid-state lighting, detailing how it still offers higher efficiency but higher costs, compared to conventional lighting. They also address the impact of nanotechnology in the biomedical field, focusing on topics such as quantum dots for bioimaging, nanoparticle-based cancer therapy, drug delivery, antibacterial agents, and more. Fills the informational gap on the wide range of applications for inorganic nanoparticles in areas including biomedicine, electronics, storage media, conservation of cultural heritage, optics, textiles, and cosmetics Assembling work from an array of experts at the top of their respective fields, this book delivers a useful analysis of the vast scope of existing and potential applications for inorganic nanoparticles. Versatile as either a professional research resource or textbook, this effective tool elucidates fundamentals and current advances associated with design, characterization, and application development of this promising and ever-evolving device.

Book Brain Computer Interfaces

    Book Details:
  • Author : Jonathan Wolpaw
  • Publisher : Oxford University Press
  • Release : 2012-01-24
  • ISBN : 0199921482
  • Pages : 419 pages

Download or read book Brain Computer Interfaces written by Jonathan Wolpaw and published by Oxford University Press. This book was released on 2012-01-24 with total page 419 pages. Available in PDF, EPUB and Kindle. Book excerpt: A recognizable surge in the field of Brain Computer Interface (BCI) research and development has emerged in the past two decades. This book is intended to provide an introduction to and summary of essentially all major aspects of BCI research and development. Its goal is to be a comprehensive, balanced, and coordinated presentation of the field's key principles, current practice, and future prospects.

Book Neural Engineering

Download or read book Neural Engineering written by Bin He and published by Springer Science & Business Media. This book was released on 2013-01-09 with total page 801 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neural Engineering, 2nd Edition, contains reviews and discussions of contemporary and relevant topics by leading investigators in the field. It is intended to serve as a textbook at the graduate and advanced undergraduate level in a bioengineering curriculum. This principles and applications approach to neural engineering is essential reading for all academics, biomedical engineers, neuroscientists, neurophysiologists, and industry professionals wishing to take advantage of the latest and greatest in this emerging field.