Download or read book WHO fungal priority pathogens list to guide research development and public health action written by World Health Organization and published by World Health Organization. This book was released on 2022-10-25 with total page 48 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book WHO bacterial priority pathogens list 2024 written by World Health Organization and published by World Health Organization. This book was released on 2024-05-17 with total page 72 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Implementing the global action plan on antimicrobial resistance written by World Health Organization and published by World Health Organization. This book was released on 2023-12-12 with total page 197 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book People centred approach to addressing antimicrobial resistance in human health written by World Health Organization and published by World Health Organization. This book was released on 2023-10-19 with total page 63 pages. Available in PDF, EPUB and Kindle. Book excerpt: This document outlines the concept and content of the WHO people-centred approach to addressing antimicrobial resistance (AMR) in the human health sector. The proposed approach recognizes and aims to address the challenges and health system barriers people face when accessing health services to prevent, diagnose and treat (drug-resistant) infections. It puts people and their needs at the centre of the AMR response and guides policy-makers in taking programmatic and comprehensive actions to mitigate AMR in line with a proposed package of core interventions. These interventions are based on a review of four pillars and two foundational steps that are critical to overcome barriers faced by people and health systems in addressing AMR. The four pillars are: (1) prevention of infections; (2) access to essential health services; (3) timely, accurate diagnosis; and (4) appropriate, quality-assured treatment. The pillars are supported by the two foundational steps: effective governance, awareness and education; and strategic information through surveillance and research. Building and adding on to the objectives of the Global action plan on AMR, the 13 core interventions and accompanying priority actions are designed to address AMR in a programmatic manner that puts people, their needs and equitable access to health services at the centre of the AMR response in the community, in primary care, secondary and tertiary care, and at national and/or subnational level. The development of the people-centred core package of AMR interventions was based on a review of the evidence and multidisciplinary expert opinion, complemented with feedback from a global online consultation and WHO’s strategic and technical advisory group on antimicrobial resistance. As countries develop or revise their national action plans (NAPs) on AMR, the people-centred core package of interventions can support the design and prioritization of actions in the human health sector at the different levels of implementation and integrated with broader health system strengthening and pandemic preparedness and response plans.

Download or read book What If Fungi Win written by Arturo Casadevall and published by JHU Press. This book was released on 2024-05-14 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt: Could fungal pathogens outsmart us before we find ways to combat them? Humans and fungi share nearly 50 percent of the same DNA. Because we're related, designing drugs to combat the varieties that attack us is a challenge. Meanwhile, in an ever hotter, wetter world, fungi may be finding new ways to thrive, queueing up global outbreak potentials for which no vaccine and woefully few medications exist; some fungi are already beginning to resist treatment. Among other lifeforms, bats, amphibians, and essential crops are also increasingly threatened by these pathogens. Enter fungal kingdom frontiersman Dr. Arturo Casadevall, an epidemiologist, professor, and inventor. Casadevall shares how the 1990s AIDS epidemic's fungal complications drove his medical mycology work, how COVID-19's fungal incidences underscore the continuing threat to the immunocompromised, and how he and his Johns Hopkins University laboratory team are discovering ways to counter the threats posed by these cunning, hungry combatants. What If Fungi Win? describes the beneficial roles of fungi along with their mischievous and deadly impacts and illustrates how committed experts like Casadevall are researching ways to save us and our food supplies. In addition to an overview of blights, lichens, molds, mushrooms, rusts, and smuts, readers will learn about: • how fungi proliferated following the mass dinosaur extinction • Oregon's ancient 2,384-acre Armillaria ostoyae—Earth's largest organism • the rye fungus ergot that may have fueled the Salem witch trials • mushrooms used to create vegan leather and eco-friendly packaging, as well as plastic-consuming fungi • why it's critical that funding institutions pay attention to fungal risks and aid scientists in their work.

Download or read book Therapeutic Rhodium Complexes written by Afzal Hussain and published by Springer Nature. This book was released on 2023-06-29 with total page 84 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the emergence and recent advances in the design and development of rhodium complexes as therapeutic agents. Different classes of anticancer rhodium complexes with particular emphasis on ligands containing nitrogen-oxygen donor atoms are presented. Anticancer rhodium complexes of N-heterocyclic carbenes are described, while half-sandwich, heterobimetallic, and multinuclear rhodium complexes are discussed. Therapeutic applications of rhodium complexes beyond cancer such as antibacterial agents or antiviral agents are also analyzed, among others. Their mechanism of action is overviewed in detail, and the authors thoroughly comment on the challenges and future outlooks of research in the development of rhodium metallodrugs. This title highlights the important research carried out in the development of therapeutic rhodium complexes and is of great interest to graduates and researchers working in the area of rhodium-based therapeutic drugs.

Download or read book Occupational and Environmental Safety and Health V written by Pedro M. Arezes and published by Springer Nature. This book was released on 2023-12-05 with total page 826 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book gathers cutting-edge research and best practices relating to occupational risk and safety management, healthcare, and ergonomics. It covers strategies for different industries, such as construction, chemical and healthcare. It emphasizes challenges posed by automation, discusses solutions offered by technologies, and reports on case studies carried out in different countries. Chapters are based on selected contributions to the 20th International Symposium on Occupational Safety and Hygiene (SHO 2023), held on July 20-21, 2023, in Portugal, as a hybrid event. By reporting on different perspectives, such as the ones from managers, employees, and OSH professionals, and covering timely issues, such as implications of telework, issues related to gender inequality and applications of machine learning techniques in occupational health, this book offers extensive information and a source of inspiration to OSH researchers, practitioners and organizations operating in both local and global contexts.

Download or read book Global report on neglected tropical diseases 2023 written by World Health Organization and published by World Health Organization. This book was released on 2023-01-30 with total page 82 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Global report on neglected tropical diseases 2023 provides a consolidated, up-to-date assessment of progress towards control, elimination and eradication of 20 diseases and disease groups (NTDs) globally, regionally and nationally. Progress is reported in the context of global commitments, strategies and targets set in the NTD road map 2021-2030. The document covers the first two years of implementation of the road map (2021 and 2022). The information presented is based primarily on epidemiological and programmatic data for interventions conducted in 2021 and gathered in 2022, but the report also describes a wide range of activities and accomplishments that were registered in both 2021 and 2022; comparisons are often made against 2020 and 2019 data, especially with regard to COVID-19 disruptions. It has four sections: Section 1 is an introduction. Section 2 presents the status of the global NTD response. Section 3 charts progress and developments against the three road map pillars. Section 4 sets out priority actions for 2023 and beyond to sustain implementation of the road map and its companion documents. Five annexes to the report provide information for 2021–2022 on regional progress (Annex 1), Weekly Epidemiology Record articles on NTDs (Annex 2), progress and challenges by disease (Annex 3), diagnostic target product profiles (Annex 4) and the status of commitments for donated medicines and health products (Annex 5).

Download or read book Advances in Molecular Pathology written by Gregory J. Tsongalis and published by Elsevier Health Sciences. This book was released on 2023-10-18 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Molecular Pathology reviews the year’s most important findings and updates within the field in order to provide molecular pathologists with the current clinical information they need to improve patient outcomes. A distinguished editorial board, led by Dr. Gregory Tsongalis, identifies key areas of major progress and controversy and invites preeminent specialists to contribute original articles devoted to these topics. These insightful overviews in molecular pathology inform and enhance clinical practice by bringing concepts to a clinical level and exploring their everyday impact on patient care. Provides in-depth, clinical reviews in molecular pathology, providing actionable insights for clinical practice. Presents the latest information in the field under the leadership of an experienced editorial team. Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews.

Download or read book Identifying common opportunistic infections among people with advanced HIV disease written by World Health Organization and published by World Health Organization. This book was released on 2024-01-16 with total page 28 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advanced HIV disease (defined in persons living with HIV with a CD4 cell count of 200cells/mm3 or presenting with a WHO Stage 3/4 AIDS-defining illness) poses a challenge to many countries globally and is responsible for significant mortality and morbidity among people living with HIV. In 2017, WHO recommended a package of care for the prevention and management of advanced HIV disease. The package was composed of screening tests, diagnostics, prophylaxis, rapid antiretroviral therarpy initiation and enhanced adherence counselling.brThe key screening and diagnostics tests are for the identification of tuberculosis, cryptococcal meningitis, histoplasmosis, and importantly, the assessment of CD4 cell count.brSupporting healthcare workers, national programmes as well as representatives of civil society in improving their understanding of how best to implement these interventions is critical for better uptake, thus improving outcomes for people living with HIV.brThis policy brief summarizes key information on the use of these interventions, based on existing WHO guidelines and recommendations.

Download or read book Point of Care Testing An Issue of the Clinics in Laboratory Medicine E Book written by Linoj Samuel and published by Elsevier Health Sciences. This book was released on 2023-05-15 with total page 193 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this issue of Clinics in Laboratory Medicine, guest editor Dr. Linoj Samuel brings his considerable expertise to the topic of Point of Care Testing. Top experts discuss the challenges, techniques, and data collection for point of care and at-home testing options for COVID-19, fungal pathogens, and STDs in various demographics, among other key topics. Contains 10 practice-oriented topics including point of care testing during the COVID-19 pandemic: challenges and pitfalls; will antigen testing remain relevant in point of care testing; the role of point of care testing in specific populations; lab at home: is at-home testing the new normal; point of care testing for sexually transmitted diseases; and more. Provides in-depth clinical reviews on point of care testing, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Download or read book Microbial Diversity and Resources in Tidal Flats written by Xue-Wei Xu and published by Frontiers Media SA. This book was released on 2024-06-06 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tidal flats are widely distributed worldwide, occupying at least 127,921 km2, of which 70% are located in coastal areas of Asia, and North and South America. As a confluence of terrestrial and marine ecosystems, tidal flat is dually influenced by these two ecosystems and becomes one of the most productive ecosystems. Rhythmic changes of environmental factors (e.g., salinity, temperature, dissolved oxygen, illumination intensity, ocean current, etc.) and frequent disturbances of human behaviour enhance organic matter as well as nitrogen, phosphorus, and sulfur compounds in tidal flats. Furthermore, tidal flats have various important ecosystem functions, including climate regulation, shoreline stabilization, carbon fixation, pollutant degradation, etc.

Download or read book Community Series in Recent Advances in Drosophila Cellular and Humoral Innate Immunity volume II written by Susanna Valanne and published by Frontiers Media SA. This book was released on 2024-06-26 with total page 116 pages. Available in PDF, EPUB and Kindle. Book excerpt: The fruit fly Drosophila melanogaster is an established tool to study mechanisms of innate immunity. Drosophila flies and larvae launch elegant humoral and cellular innate immune responses against bacteria, viruses, fungi and parasites. The humoral immune response is based on microbial recognition primarily by peptidoglycan recognition proteins leading to the production of antimicrobial peptides (AMPs). In the past few decades, Drosophilists have dissected how flies react to systemic bacterial and fungal infections at the molecular level and shown how these mechanisms are conserved from human to man. Fly humoral immune response is mainly mediated by two evolutionarily conserved NF-κB signaling pathways, the Toll and the Immune deficiency (Imd) pathways. The discovery of the Toll receptor as a key regulator of immune response, first in cultured Drosophila cells and then in Drosophila in vivo, formed the basis of the Toll-Like Receptor (TLR) research in humans and mammals. More recently, this field has broadened considerably, including e.g. the antimicrobial responses taking place in the gut. Another interesting aspect related to innate immunity is the antiviral immune mechanisms found in Drosophila. Best understood are the mechanisms based on RNAi, primarily against RNA virus infections. More recently, the evolutionarily conserved molecule STING has been shown to integrate responses against both viruses and bacteria.

Download or read book Advanced Physiology and Pathophysiology written by Nancy Tkacs, PhD, RN and published by Springer Publishing Company. This book was released on 2024-03-22 with total page 1049 pages. Available in PDF, EPUB and Kindle. Book excerpt: 2020 AJN Book-of-the-Year Award Winner: Advanced Practice Nursing! Concise and well-organized, this advanced physiology and pathophysiology text promotes deep understanding of key pathophysiological concepts and relates them to major disorders commonly seen in practice. It is distinguished by its stellar organization and writing that clarifies difficult-to-understand disease mechanisms. The second edition offers several new features that add to its value in preparing the student clinician to care for patients with a broad variety of disorders effectively. The second edition retains the inclusive language and conceptual organization central to the appeal and usefulness of the first edition. Coverage of new scientific advances update the original disease descriptions. With the aim of preparing students to be well-informed and confident decision makers in primary care settings, the text provides the key knowledge required to master pharmacology for prescriptive practice. Addressing both healthy organ function and disease-associated changes, it details and illustrates the cellular structure and function of each organ system and mechanisms of associated major clinical disorders. It examines the reasons patients often present with particular symptoms, the rationale for ordering specific diagnostic tests and interpretation of the results, and common management strategies that proceed from the underlying pathology. The text is replete with case presentations to illustrate concepts, over 500 images, key points at the end of each chapter to reinforce knowledge, and a glossary defining correct terminology. Comprehensive instructor resources accompany the text. New to the Second Edition: Standardized template for pediatric and gerontology content for clarity Expanded coverage of neonatal and pediatric development and vulnerabilities Methylation patterns of cell-free DNA (epigenetics) in oncology practice Expanded coverage of fluid and electrolyte balance Physiology of pregnancy, labor, and delivery Increased content on the social determinants of health Introduction of the exposome concept in human disease New content on biological and psychosocial aspects of human sexual development and variations relevant to LGBTQ+ centered care COVID-19-related concerns Key Features: Includes comprehensive lifespan considerations with key insights from specialists in pediatric and geriatric pathophysiology Integrates critical thinking questions and case studies to promote discussion and information synthesis Provides unique Bridge to Clinical Practice in each chapter to translate science to practical patient care Includes more than 500 images to illustrate complex scientific concepts Summarizes content with key points at the end of each chapter

Download or read book The Last of Us and Theology written by Peter Admirand and published by Rowman & Littlefield. This book was released on 2024-05-29 with total page 251 pages. Available in PDF, EPUB and Kindle. Book excerpt: With a catastrophic fungal pandemic, the post-apocalypse, a moral quest despite societal breakdowns, humans hunting humans or morphed into grotesque infected, The Last of Us video games and HBO series have exhilarated, frightened, and broken the hearts of millions of gamers and viewers. The Last of Us and Theology: Violence, Ethics, Redemption? is a richly diverse and probing edited volume featuring essays from academics across the world to examine theological and ethical themes from The Last of Us universe. Divided into three groupings—Violence, Ethics, and Redemption?—these chapters will especially appeal to The Last of Us fans and those interested in Theology and Pop Culture more broadly. Chapters not only grapple with theologians, ethicists, and novelists like Cormac McCarthy, Fyodor Dostoevsky, Martin Buber, and Paul Tillich; and theological issues from forgiveness and theodicy to soteriology and eschatology; but will help readers become experts on all things fireflies, clickers, Cordyceps, and Seraphites. “Save who you can save” and “Look for the Light.”

Download or read book Cryptococcus Neoformans written by Erin E. McClelland and published by Springer Nature. This book was released on 2024 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume explores the latest developments in the study of Cryptococcus neoformans and its pathology, along with discussion on newly used therapeutics. The chapters in this book cover a wide range of protocols commonly used in Cryptococcus research such as animal models, genetics techniques, virulence factor phenotyping, and microscopy. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Cryptococcus neoformans: Methods and Protocols is a valuable resource that will help researchers further enhance their understanding of this pathogenic yeast, and will aid in new discoveries and therapeutics. .

Download or read book Sustainable Health in Low and Middle Income Countries written by Fingani Mphande and published by Springer Nature. This book was released on 2023-08-04 with total page 151 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book highlights lessons from the COVID-19 pandemic and explains how these can be used to build sustainable health systems, especially in Low- and Middle-Income Countries (LMIC). It investigates the impact of outbreak response and management on health sustainability in LMIC from the perspective of SDG3: “Ensuring healthy lives and wellbeing for all at all ages”. Despite strides being made in some areas for SDG target 3.3 to fight communicable diseases, the COVID-19 pandemic has caused interruptions that will considerably affect vaccination coverage as well as the progress that was made, for example: in reducing malaria cases. Vulnerable populations who were already struggling to access their healthcare needs before the pandemic may face even greater challenges at present and in the years to come, post-pandemic. This book considers the progress on attaining the SDG3 targets, specifically: to improve early warning systems for management of national and global health risks, and the effect of pandemics - including but not limited to the COVID-19 pandemic - and emerging disease outbreaks. It explores the weaknesses and strengths in LMIC and how to strengthen capacities in these countries. The author also investigates and proposes approaches that can, or should, be implemented to ensure sustainable health systems in developing countries, including early warning systems, risk reduction, and the management of global and national health risks. This book is of great interest to public health professionals, infectious diseases experts, and epidemiologists, as well as students and researchers of public health systems and healthcare infrastructure in developing countries.