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Book Vitamin D   Chemical  Biochemical and Clinical Endocrinology of Calcium Metabolism

Download or read book Vitamin D Chemical Biochemical and Clinical Endocrinology of Calcium Metabolism written by A. W. Norman and published by Walter de Gruyter GmbH & Co KG. This book was released on 2020-10-26 with total page 1319 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Assay of Calcium regulating Hormones

Download or read book Assay of Calcium regulating Hormones written by Daniel Bikle and published by Springer. This book was released on 1983-10-03 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: The ability to measure accurately the hormones regulating calcium homeosta sis is the fundamental first step toward understanding the roles these hormones play in health and disease. Techniques for such measurements have only been available for the past 10 years or so and remain in a state of rapid development. Sensitive parathyroid hormone (PTH) radioimmunoassays appeared in the early 1970s, and with them came a whole new appreciation for the prevalence and implications of hyperparathyroidism, primary or secondary, in the popu lation. The calcitonin (CT) radioimmunoassay came later and achieved rapid success in the. diagnosis of a previously poorly understood cancer, medullary carcinoma of the thyroid, frequently associated with the familial multiple endo crine neoplasia type 2 syndromes (a and b). As the sensitivity of the calcitonin radioimmunoassay has improved, our understanding of the role of calcitonin in normal physiological processes has increased. The knowledge that vitamin D must be metabolized to produce its biologic effects is only 15 years old. This has had profound implications in our understanding of a variety of metabolic bone, kidney, and gastrointestinal diseases. Assays to measure the major cir culating form of vitamin D, 25-hydroxyvitamin D, were described 10 years ago. Assays for the other metabolites, in particular, 1,25-dihydroxyvitamin D, were described even more recently. As of today, we know of many vitamin D metabolites and have developed the techniques to measure most of them; how ever, many questions remain concerning their physiological role.

Book Vitamin D   Biochemical  Chemical and Clinical Aspects Related to Calcium Metabolism

Download or read book Vitamin D Biochemical Chemical and Clinical Aspects Related to Calcium Metabolism written by A. W. Norman and published by Walter de Gruyter GmbH & Co KG. This book was released on 2020-10-26 with total page 1016 pages. Available in PDF, EPUB and Kindle. Book excerpt: No detailed description available for "Vitamin D - Biochemical, Chemical and Clinical Aspects Related to Calcium Metabolism".

Book Vitamin D

    Book Details:
  • Author : A. W. Norman
  • Publisher : Walter de Gruyter
  • Release : 2011-07-11
  • ISBN : 3110846713
  • Pages : 1116 pages

Download or read book Vitamin D written by A. W. Norman and published by Walter de Gruyter. This book was released on 2011-07-11 with total page 1116 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Vitamin D

    Book Details:
  • Author : Martin Hewison
  • Publisher : Academic Press
  • Release : 2017-12-14
  • ISBN : 0128099666
  • Pages : 1182 pages

Download or read book Vitamin D written by Martin Hewison and published by Academic Press. This book was released on 2017-12-14 with total page 1182 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vitamin D: Volume One: Biochemistry, Physiology and Diagnostics, Fourth Edition, presents the latest information from international experts in endocrinology, bone biology and human physiology, taking readers through the basic research of vitamin D. This impressive reference presents a comprehensive review of the multifaceted vitamin D. Researchers from all areas will gain insight into how clinical observations and practices can feed back into the research cycle, thus allowing them to develop more targeted genomic and proteomic insights on the mechanisms of disease. - Offers a comprehensive reference, ranging from basic bone biology, to biochemistry, to the clinical diagnostic and management implications of vitamin D - Saves researchers and clinicians time in quickly accessing the very latest details on the diverse scientific and clinical aspects of Vitamin D, as opposed to searching through thousands of journal articles - Targets chemistry, metabolism and circulation, mechanisms of action, mineral and bone homeostasis, human physiology, diagnosis and management, nutrition, sunlight, genetics and vitamin D deficiency - Volume II of this collection presents a clinical focus on disorders, analogs, cancer; immunity, inflammation and disease and therapeutic applications

Book Vitamin D

    Book Details:
  • Author : Michael F. Holick
  • Publisher : Springer Science & Business Media
  • Release : 2013-03-09
  • ISBN : 1475728611
  • Pages : 456 pages

Download or read book Vitamin D written by Michael F. Holick and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Nutrition and Health series of books has as an overriding mission to provide health professionals with texts that are considered essential because each includes: a synthesis of the state of the science; timely, in-depth reviews by the leading researchers in their respective fields; extensive, up-to-date fully annotated reference lists; a detailed index; relevant tables and figures; identification of paradigm shifts and the consequences; of information between chapters, but targeted, inter-chapter refer virtually no overlap rals, suggestions of areas for future research; and balanced, data-driven answers to patient questions that are based on the totality of evidence rather than the findings of any single study. The series volumes are not the outcome of a symposium. Rather, each editor has the potential to examine a chosen area with a broad perspective, both in subject matter as well as in the choice of chapter authors. The international perspective, especially with regard to public health initiatives, is emphasized where appropriate. The editors, whose training is both research and practice oriented, have the opportunity to develop a primary objective for their book, define the scope and focus, and then invite the leading authori ties from around the world to be part of their initiative. The authors are encouraged to provide an overview of the field, discuss their own research, and relate the research de findings to potential human health consequences.

Book Vitamin D

Download or read book Vitamin D written by Anthony W. Norman and published by . This book was released on 1985 with total page 1306 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Vitamin D

    Book Details:
  • Author : Anthony Norman
  • Publisher : Elsevier
  • Release : 2012-12-02
  • ISBN : 0323141439
  • Pages : 509 pages

Download or read book Vitamin D written by Anthony Norman and published by Elsevier. This book was released on 2012-12-02 with total page 509 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vitamin D: The Calcium Homeostatic Steroid Hormone provides a continuing coordinated group of edited critiques of the dynamic state of the science and art of nutrition. The most recent basic advances will be reviewed within the broad framework of the scientific knowledge of food and nutrition, including its application to man, individually and societally. The volumes, authored singly or by invited contributors, will appeal to serious scholars concerned with pure or applied nutrition. This volume comprises 13 chapters, with the first discussing the progress of vitamin D-cholecalciferol from vitamin to steroid hormone. Succeeding chapters then discuss the biological and chemical assay of vitamin D, its metabolites, and analogs; metabolism of vitamin D; and the tissue and subcellular localization of vitamin D and its metabolites. Other chapters cover binding proteins and receptors for vitamin D and its metabolites; interrelationships between vitamin D and other hormones; intestinal effects of vitamin D; vitamin D actions in the kidney; vitamin D actions on bone; and vitamin D and its clinical relationships. This book will be of interest to practitioners in the fields of chemistry, nutrition, and medicine.

Book Vitamin D

    Book Details:
  • Author : Anthony W. Norman
  • Publisher :
  • Release : 1982
  • ISBN :
  • Pages : pages

Download or read book Vitamin D written by Anthony W. Norman and published by . This book was released on 1982 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Vitamin D

    Book Details:
  • Author : H.F. DeLuca
  • Publisher : Springer Science & Business Media
  • Release : 2012-12-06
  • ISBN : 3642813062
  • Pages : 150 pages

Download or read book Vitamin D written by H.F. DeLuca and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 150 pages. Available in PDF, EPUB and Kindle. Book excerpt: Because diseases of the bone are often less acute and less lifethreatening than dis eases of the circulatory system, gastrointestinal tract, kidney, liver, and the nervous system, they have received a disproportionately smaller amount of attention in the medical world. With the average increasing life span of man as a result of improve ments in modern medicine, espe~ially in the pediatric field, the seriousness of many metabolic bone diseases has indeed become more obvious. In addition, other improvements in medicine, such as hemodialysis for the preservation of renal failure patients, have permitted the development of other consequences of diseased kidneys, one of which is the appearance of renal osteodystrophy. Finally, the appearance of several genetic disorders in the area of metabolic bone disease has been underscored by the solution of other pediatric diseas~s of much more serious consequences. These emerging problems all suggest that much remains to be learned concerning the sys temic control of bone, both as a structural organ and as a reservoir for the important elements of calcium and phosphorus so essential for the support of life in complex multicellular organisms of which man is the most important. As will be demonstrated in the historical portion of this manuscript, the existence of the three most important humoral factors regulating bone metabolism and func tion are now known.

Book Calcium Regulating Hormones  Vitamin D Metabolites  and Cyclic AMP Assays and Their Clinical Application

Download or read book Calcium Regulating Hormones Vitamin D Metabolites and Cyclic AMP Assays and Their Clinical Application written by Heinrich Schmidt-Gayk and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Calcium metabolism is regulated by three specific hormones: parathor- mone, calciferol metabolites, and calcitonin. Cyclic AMP also plays an important part in calcium regulation, and its concentration in urine can be taken as a measure of parathyroid function. Methods for quantitative measurement of, e.g. calcium-regulating hormones and vitamin D metabolites as well as of cAMP are absolutely necessary for safe differential diagnosis of diseases of the parathyroid like hypo- and hyperparathyroidism. In this monograph all presently available methods are summarized as to whether they can already be obtained as test kits or are still being tested. Radioimmunoassays for the various peptide fragments such as 53-84, 44-68, 28-48, and 1-34 are described, as are immunochemiluminescence methods and adenylate cyclase bioassays. The same is true for the vitamin D metabolites, where the various assays for calcidiol and calcitriol such as HPLC, protein-binding assay with second antibody separation, and double antibody RIA are deA scribed. Finally, determination of calcitonin and cAMP is discussed in detail. This is a practically and clinically oriented monograph for working in the fields of internal medicine, endocrinology, and laboratory medicine.

Book Vitamin D

    Book Details:
  • Author : Martin Hewison
  • Publisher : Academic Press
  • Release : 2017-12-14
  • ISBN : 012809964X
  • Pages : 1268 pages

Download or read book Vitamin D written by Martin Hewison and published by Academic Press. This book was released on 2017-12-14 with total page 1268 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vitamin D: Volume 2: Health, Disease and Therapeutics, Fourth Edition, authoritatively covers the evidence for new roles for vitamin D, ranging from cardiovascular disease, to cancer, diabetes, inflammatory bowel disease, multiple sclerosis and renal disease. This collection represents a who's who of vitamin D research and the coverage is appropriately broad, drawing in internal medicine, orthopedics, oncology and immunology. Clinical researchers will gain a strong understanding of the molecular basis for a particular area of focus. - Offers a comprehensive reference, ranging from basic bone biology, to biochemistry, to the clinical diagnostic and management implications of vitamin D - Saves researchers and clinicians time in quickly accessing the very latest details on the diverse scientific and clinical aspects of Vitamin D, as opposed to searching through thousands of journal articles - Chapter authors include the most prominent and well-published names in the field - Targets chemistry, metabolism and circulation, mechanisms of action, mineral and bone homeostasis and vitamin D deficiency - Presents a clinical focus on disorders, analogs, cancer, immunity, inflammation, disease and therapeutic applications

Book Clinical Endocrinology of Calcium Metabolism

Download or read book Clinical Endocrinology of Calcium Metabolism written by T. John Martin and published by Marcel Dekker. This book was released on 1987 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Vitamin D in Clinical Medicine

    Book Details:
  • Author : A. Giustina
  • Publisher : Karger Medical and Scientific Publishers
  • Release : 2018-03-29
  • ISBN : 3318063398
  • Pages : 216 pages

Download or read book Vitamin D in Clinical Medicine written by A. Giustina and published by Karger Medical and Scientific Publishers. This book was released on 2018-03-29 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vitamin D deficiency is prevalent today not only among the elderly but pervasively throughout all ages of life.This is due, in part, to systemic diseases that affect vitamin D metabolism, to changes in lifestyle, such as insufficient exposure to sunlight, and to increased use of sunscreen. Apart from the obvious effects of vitamin D deficiency on skeletal metabolism, the problem is assuming even greater significance because observational and interventional studies have linked vitamin D deficiency to cardiovascular disease, cancer, and diabetes. This book addresses a variety of important issues that have emerged from this fast-moving area of clinical medicine. The topics include assays of vitamin D and its binding protein, effects on aging and associated complications, primary and secondary states of altered parathyroid hormone secretion, vitamin D in the growing years of children and adolescents, nutritional requirements, and vitamin D as it relates to systemic disorders such as diabetes mellitus. Vitamin D in Clinical Medicine aims to offer new insights, in an evidence-based way, on important issues related to vitamin D. It is written for general practitioners and internists, as well as for endocrinologists, nutritionists, pulmonologists, cardiologists, and oncologists.

Book Vitamin D

    Book Details:
  • Author : Anthony W. Norman
  • Publisher : Walter de Gruyter GmbH & Co KG
  • Release : 2020-10-12
  • ISBN : 3110882515
  • Pages : 1002 pages

Download or read book Vitamin D written by Anthony W. Norman and published by Walter de Gruyter GmbH & Co KG. This book was released on 2020-10-12 with total page 1002 pages. Available in PDF, EPUB and Kindle. Book excerpt: