Download or read book Viral and Mycoplasmal of Laboratory Rodents written by Pravin Bhatt and published by Elsevier. This book was released on 2012-12-02 with total page 861 pages. Available in PDF, EPUB and Kindle. Book excerpt: Viral and Mycoplasmal Infections of Laboratory Rodents: Effects on Biomedical Research contains the proceedings of a conference held at the National Institutes of Health on October 24-26, 1984. Organized into four parts, this book begins by elucidating the basic biology and pathogenetic mechanisms of viral and mycoplasmal infections. The presence of known and potential research complications due to these infections is also addressed. Lastly, the detection, control, and prevention of infection in rodent colonies are discussed.
Download or read book Complications of Viral and Mycoplasmal Infections in Rodents to Toxicology Research and Testing written by Chemical Industry Institute of Toxicology. Conference and published by Garland Science. This book was released on 1986 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book VIRAL AND MYCOPLASMAL INFECTIONS OF LABORATORY RODENTS EFFECTS ON BIOMEDICAL RESEARCH written by and published by . This book was released on 1986 with total page 844 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Manual of Microbiologic Monitoring of Laboratory Animals written by Kim Waggie and published by DIANE Publishing. This book was released on 1994 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: An overview of the main infectious agents and diseases of mice and rats. Indicates the methods used in testing for them. Includes 42 agents for monitoring. Also deals with microbiologic monitoring of immunodeficient animals. Includes viruses, bacteria, mycoplasmas and fungi, and parasites. Each agent's description includes classification and morphology; cultivation; strains; characteristics of infection; geographic distribution; means of spread; morbidity and mortality; control prevention; and test procedures. Extensive bibliography with each agent.
Download or read book Infectious Diseases of Mice and Rats written by National Research Council and published by National Academies Press. This book was released on 1991-02-01 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new editionâ€"a must for all researchers who use these lab animalsâ€"provides practical suggestions for breeding, keeping, and identifying pathogen-free laboratory rodents. It contains three informative sections. The first, Principles of Rodent Disease Prevention, summarizes methods for eliminating infectious agents. It offers information on pathogen terminology; pathogen status of rodents; and breeding, transporting, isolating, testing, and diagnosing rodents. The second section, Individual Disease Agents and Their Effects on Research, describes the diagnosis and control of each infectious agent, and the last section, Diagnostic Indexes: Clinical Signs, Pathology, and Research Complications, contains informative tables covering all the diseases listed in the volume, arranged to help in the diagnosis of infected animals.
Download or read book Rodents written by National Research Council and published by National Academies Press. This book was released on 1996-08-08 with total page 179 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the 15 years since the last Institute of Laboratory Animal Resources report on the general management of rodents was published, important advances in biomedical research and increased public awareness have created a new environment for animal research. Modern technology-such as insertion of functional genes from other species into mice or rats, elimination of a single selected gene or function in mice, and the re-creation of elements of the human immune system in mice-has greatly expanded the usefulness of rodents in drug development and as models of human diseases. The technologic requirements of such advanced systems have led to improved understanding and implementation of environmental requirements for the care and use of rodents in research. The intent of this report is to provide current information to laboratory animal scientists (including both animal-care technicians and veterinarians), investigators, research technicians, and administrators on general elements of rodent care and use that should be considered both for optimal design and conduct of research and to meet current standards of care and use.
Download or read book Digestive System written by Thomas Carlyle Jones and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 465 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the second edition of the third volume in the Monographs on Pathology of Laboratory Animals series. Since the first edition, new information has developed at a remarkable pace. Both editions propose standardized nomenclature that is being used internationally, gaining significant acceptance. The result is improved communications of pathologic data to regulatory agencies and in scientific publications worldwide. New information on the nature and variability of preneoplastic lesions in the liver of laboratory rodents is included in this edition. The book expands data on the accompanying changes in enzyme activity in affected liver cells. Spongiosis hepatis in the rat and its relation to spongiotic pericytoma are discussed thoroughly. Information on many other pathologic entities is brought up to date and new ones are added to this second edition, making it an even more useful and expanded reference text.
Download or read book Pathology of Laboratory Rodents and Rabbits written by Dean H. Percy and published by Wiley-Blackwell. This book was released on 2008-01-09 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pathology of Laboratory Rodents and Rabbits has become a standard text for both veterinary pathologists and veterinarians in laboratory animal medicine. Newly recognized infectious diseases continue to emerge and molecular methods for studying infectious agents are becoming widely used for the classification of these and previously known pathogens. With the ongoing development and perfection of genetic engineering techniques, the use of genetically engineered mice in the research laboratory continues to grow exponentially. This new edition features updates throughout with increased emphasis on timely topics such as infectious diseases in genetically engineered mice. Diseases covered include viral infections, bacterial infections, parasitic diseases, nutritional and metabolic disorders, behavioral disorders, aging and degenerative disorders, environment-related disease, and neoplasms. Organized by species, coverage includes mice, rats, hamsters, gerbils, guinea pigs, and rabbits. Veterinary pathologists, laboratory animal veterinarians, and students will appreciate the concise organization and easily accessible information on key diagnostic features, differential diagnoses, and significance of diseases.
Download or read book Microbial and Phenotypic Definition of Rats and Mice written by National Research Council and published by National Academies Press. This book was released on 1999-08-26 with total page 114 pages. Available in PDF, EPUB and Kindle. Book excerpt: US-Japan meetings on laboratory animal science have been held virtually every year since 1980 under the US-Japan Cooperative Program on Science and Technology. Over the years these meetings have resulted in a number of important documents including the Manual of Microbiologic of Monitoring of Laboratory Animals published in 1994 and the article Establishment and Preservation of Reference Inbred Strains of Rats for General Purposes published in 1991. In addition to these publications, these meetings have been instrumental in increasing awareness of the need for microbiologic monitoring of laboratory rodents and the need for genetic definition and monitoring of mice and rats.
Download or read book Gnotobiotics written by Trenton R Schoeb and published by Academic Press. This book was released on 2017-08-11 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gnotobiotics summarizes and analyzes the research conducted on the use of gnotobiotes, providing detailed information regarding actual facility operation and derivation of gnotobiotic animals. In response to the development of new tools for microbiota and microbiome analysis, the increasing recognition of the various roles of microbiota in health and disease, and the consequent expanding demand for gnotobiotic animals for microbiota/microbiome related research, this volume collates the research of this expanding field into one definitive resource. Reviews and defines gnotobiotic animal species Analyzes microbiota in numerous contexts Presents detailed coverage of the protocols and operation of a gnotobiotic facility
Download or read book Rodents written by Institute of Laboratory Animal Resources (U.S.). Committee on Rodents and published by Laboratory Animal Management S. This book was released on 1996-08-19 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the 15 years since the Institute of Laboratory Animal Resources issued its last report on the general management of rodents, advances in biomedical technology and increased public awareness of laboratory animal issues have created a new research environment. This book brings researchers up to date on both of these aspects of laboratory investigation and provides a comprehensive resource manual for management of laboratory rodents. It reviews relevant laws and ethical considerations, and it examines the role and responsibilities of mandatory institutional animal care and use committees. The expert panel addresses animal selection, sources of laboratory rodents, nomenclature and record keeping, management of genetically and nongenetically defined colonies, and management of animals with special needs. Investigators will find detailed guidance on housing, environment, sanitation, diet and caloric restriction, and facilities design.
Download or read book Essentials of Laboratory Animal Science Principles and Practices written by P. Nagarajan and published by Springer Nature. This book was released on 2021-07-23 with total page 797 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book comprehensively reviews the anatomy, physiology, genetics and pathology of laboratory animals as well as the principles and practices of using laboratory animals for biomedical research.It covers the design of buildings used for laboratory animals, quality control of laboratory animals, and toxicology, and discusses various animal models used for human diseases. It also highlights aspects, such as handling and restraint and administration of drugs, as well as breeding and feeding of laboratory animals, and provides guidelines for developing meaningful experiments using laboratory animals.Further, the book discusses various alternatives to animal experiments for drug and chemical testing, including their advantages over the current approaches. Lastly, it examines the potential effect of harmful pathogens on the physiology of laboratory animals and discusses the state of art in in vivo imaging techniques.The book is a useful resource for research scientists, laboratory animal veterinarians, and students of laboratory animal medicine.
Download or read book The Welfare of Laboratory Animals written by Eila Kaliste and published by Springer Science & Business Media. This book was released on 2007-04-18 with total page 351 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book examines the general principles of laboratory animal maintenance and experimental use as well as factors that have to be taken into account when good research is done with animals. In addition, it provides species specific coverage, concentrating on the species most used as laboratory animals. The book gives a comprehensive description of the welfare questions considered to be important for each species under laboratory conditions.
Download or read book Guide for the Care and Use of Laboratory Animals written by National Research Council and published by National Academies Press. This book was released on 2011-01-27 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: A respected resource for decades, the Guide for the Care and Use of Laboratory Animals has been updated by a committee of experts, taking into consideration input from the scientific and laboratory animal communities and the public at large. The Guide incorporates new scientific information on common laboratory animals, including aquatic species, and includes extensive references. It is organized around major components of animal use: Key concepts of animal care and use. The Guide sets the framework for the humane care and use of laboratory animals. Animal care and use program. The Guide discusses the concept of a broad Program of Animal Care and Use, including roles and responsibilities of the Institutional Official, Attending Veterinarian and the Institutional Animal Care and Use Committee. Animal environment, husbandry, and management. A chapter on this topic is now divided into sections on terrestrial and aquatic animals and provides recommendations for housing and environment, husbandry, behavioral and population management, and more. Veterinary care. The Guide discusses veterinary care and the responsibilities of the Attending Veterinarian. It includes recommendations on animal procurement and transportation, preventive medicine (including animal biosecurity), and clinical care and management. The Guide addresses distress and pain recognition and relief, and issues surrounding euthanasia. Physical plant. The Guide identifies design issues, providing construction guidelines for functional areas; considerations such as drainage, vibration and noise control, and environmental monitoring; and specialized facilities for animal housing and research needs. The Guide for the Care and Use of Laboratory Animals provides a framework for the judgments required in the management of animal facilities. This updated and expanded resource of proven value will be important to scientists and researchers, veterinarians, animal care personnel, facilities managers, institutional administrators, policy makers involved in research issues, and animal welfare advocates.
Download or read book Guidelines for the Humane Transportation of Research Animals written by National Research Council and published by National Academies Press. This book was released on 2006-08-14 with total page 165 pages. Available in PDF, EPUB and Kindle. Book excerpt: Arranging the transportation of animals at research facilities is often an ordeal. There is a confusing patchwork of local, national, and international regulations; a perceived lack of high-quality shipping services; a dearth of science-based good practices; and a lack of biosafety standards. It's a challenge â€"and an impediment to biomedical research. Guidelines for the Humane Transportation of Research Animals identifies the current problems encountered in the transportation of research animals and offers recommendations aimed at local and federal officials to rectify these problems. This book also includes a set of good practices based on the extensive body of literature on transportation of agricultural animals, universal concepts of physiology, and a scientific understanding of species-specific needs and differences. Good practices were developed by the committee to address thermal environment, space requirements, food and water requirements, social interaction, monitoring of transportation, emergency procedures, personnel training, and biosecurity. Guidelines for the Humane Transportation of Research Animals is an essential guide for all researchers, animal care technicians, facilities managers, administrators, and animal care and use committees at research institutions.
Download or read book Molecular Biology and Pathogenicity of Mycoplasmas written by Shmuel Razin and published by Springer Science & Business Media. This book was released on 2007-05-08 with total page 574 pages. Available in PDF, EPUB and Kindle. Book excerpt: was the result of the efforts of Robert Cleverdon. The rapidly developing discipline of molecular biology and the rapidly expanding knowledge of the PPLO were brought together at this meeting. In addition to the PPLO specialists, the conference invited Julius Marmur to compare PPLO DNA to DNA of other organisms; David Garfinkel, who was one of the first to develop computer models of metabolism; Cyrus Levinthal to talk about coding; and Henry Quastler to discuss information theory constraints on very small cells. The conference was an announcement of the role of PPLO in the fundamental understanding of molecular biology. Looking back 40-some years to the Connecticut meeting, it was a rather bold enterprise. The meeting was international and inter-disciplinary and began a series of important collaborations with influences resonating down to the present. If I may be allowed a personal remark, it was where I first met Shmuel Razin, who has been a leading figure in the emerging mycoplasma research and a good friend. This present volume is in some ways the fulfillment of the promise of that early meeting. It is an example of the collaborative work of scientists in building an understanding of fundamental aspects of biology.
Download or read book Manual of Microbiologic Monitoring of Laboratory Animals written by Kim Waggie and published by . This book was released on 1994-05 with total page 339 pages. Available in PDF, EPUB and Kindle. Book excerpt: An overview of the main infectious agents and diseases of mice and rats. Indicates the methods used in testing for them. Includes 42 agents for monitoring. Also deals with microbiologic monitoring of immunodeficient animals. Includes viruses, bacteria, mycoplasmas and fungi, and parasites. Each agent's description includes classification and morphology; cultivation; strains; characteristics of infection; geographic distribution; means of spread; morbidity and mortality; control prevention; and test procedures. Extensive bibliography with each agent.
