Download or read book Annual Reports in Medicinal Chemistry written by and published by Academic Press. This book was released on 1985-09-11 with total page 367 pages. Available in PDF, EPUB and Kindle. Book excerpt: Annual Reports in Medicinal Chemistry

Download or read book Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on with total page 1144 pages. Available in PDF, EPUB and Kindle. Book excerpt: First multi-year cumulation covers six years: 1965-70.

Download or read book National Library of Medicine Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on 1993 with total page 690 pages. Available in PDF, EPUB and Kindle. Book excerpt: First multi-year cumulation covers six years: 1965-70.

Download or read book Muscarinic Receptor Subtypes in the GI Tract written by G. Lux and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 95 pages. Available in PDF, EPUB and Kindle. Book excerpt: The differentiation between the muscarinic and the nicotinic ef fects of acetylcholine led to the subdivision of the cholinergic ner vous system into two categories. Further studies showed that stimu lating and inhibiting muscarinic effects could be demonstrated in different organs. For instance, gastric secretion and gastrointestinal motility are stimulated, while heart rate and the vascular muscula ture are inhibited. For decades, it could not be determined whether the various ef fects were mediated by different subgroups of muscarinic receptors, but eventually, with the availability of agonists and antagonists to muscarinic receptors, and using various techniques, the existence of at least two such subgroups could be ascertained . . Mt receptors are defined by their high affinity for the antagonist pirenzipine in comparison to M2 receptors. This subdivision of muscarinic receptors has since been proved beyond doubt by experi ments in vivo and in vitro, by receptor binding studies, by histoauto radiography, and by electrophysiological studies. However, these different classes of muscarinic receptors have not been found to relate to different types of effects; instead both excit atory and inhibitory effects appear to be linked to each class. For ex ample, excitation of gut motility and inhibition of cardiac contrac tile activities both appear to be mediated by M2 receptors, while ex citation of some nerves in sympathetic ganglia and inhibition of some myenteric nerves may be mediated by M receptors.

Download or read book 8th European Medical and Biological Engineering Conference written by Tomaz Jarm and published by Springer Nature. This book was released on 2020-11-29 with total page 1198 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book aims at informing on new trends, challenges and solutions, in the multidisciplinary field of biomedical engineering. It covers traditional biomedical engineering topics, as well as innovative applications such as artificial intelligence in health care, tissue engineering , neurotechnology and wearable devices. Further topics include mobile health and electroporation-based technologies, as well as new treatments in medicine. Gathering the proceedings of the 8th European Medical and Biological Engineering Conference (EMBEC 2020), held on November 29 - December 3, 2020, in Portorož, Slovenia, this book bridges fundamental and clinically-oriented research, emphasizing the role of education, translational research and commercialization of new ideas in biomedical engineering. It aims at inspiring and fostering communication and collaboration between engineers, physicists, biologists, physicians and other professionals dealing with cutting-edge themes in and advanced technologies serving the broad field of biomedical engineering.

Download or read book The Muscarinic Receptors written by Joan Heller Brown and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 485 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research on muscarinic receptors is advancing at an extraordinary rate. Ten years ago, the existence of muscarinic receptor sub types was a logical assumption with only scattered experimen tal support. The discovery that pirenzepine recognized apparent heterogeneity in muscarinic binding sites infused new life into the problem of subclassifying muscarinic receptors. Simultaneous advances in molecular biology created a frenzy to clone cell sur face receptors. The muscarinic receptor succumbed surprisingly quickly, revealing its structure and that of at least four closely related gene products within a year. Our hope of obtaining clear evidence for muscarinic receptor subtypes was answered with a vengeance. Now a family of muscarinic receptors sits before us, asking to be understood. The bounty is as attractive to those who have not previously studied muscarinic receptors as to those who have dedicated their research careers to this subject. The goal of this book is to ensure that the new generation of research will profit from the wisdom of the past. The tools of molecular biology are well suited to the tasks of characteriz ing the pharmacology, function, and regulation of the distinct muscarinic receptor subtypes. However, efficient and intelligent use of these tools is not possible, unless one understands the properties of the receptor, the molecular mechanisms by which it couples to effectors, and the ways that it is regulated.

Download or read book Advances in Drug Research written by Bernard Testa and published by Elsevier. This book was released on 2013-10-22 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Drug Research, Volume 20 focuses on the general themes of drug research and description of specific drug classes. This book is divided into four chapters. Chapter 1 discusses the extrapolation of toxicological and pharmacological data from animals to humans. The second chapter deals with the tissue binding of drugs, considering the relative ponderal importance of tissue versus blood macromolecules. The therapeutic use of plants and consumption of medicinal plants are elaborated in Chapter 3. The last chapter covers the field of histaminergic agonists and antagonists, describing breakthroughs such as H2-receptor antagonists, non-sedating H1-receptor antagonists, and H3-receptors. This publication is valuable to drug researchers and students interested in advances in drugs.

Download or read book Progress in Medicinal Chemistry written by and published by Elsevier. This book was released on 1985-01-01 with total page 303 pages. Available in PDF, EPUB and Kindle. Book excerpt: Progress in Medicinal Chemistry

Download or read book Proceedings of 8th Edition of International Conference on Clinical Medical CASE REPORTS 2018 written by EuroScicon and published by EuroScicon. This book was released on 2018-05-22 with total page 76 pages. Available in PDF, EPUB and Kindle. Book excerpt: May 28-29, 2018 | London, Uk Key Topics : Dentistry Case Reports, Pediatrics Case Reports, Cardiology Case Reports, Neurology And Neuroscience Case Reports, Human Pathology Case Reports, Oncology Case Reports, Drug Interactions Case Reports, Public And Mental Health Case Reports, Obstetrics & Gynecology Case Reports, Surgery Case Reports, Medical Genetics Case Reports, Clinical Microbiology And Infectious Diseases Case Reports, Anesthesiology Case Reports, Medicine Case Reports, Gastroenterology Case Reports, Proctology/Colorectal Surgery Case Reports, Radiology Case Reports, Case Reports In Endocrinology And Diabetes, Case Reports In Opthalmology, Case Reports In Clinical Autopsy, Miscellaneous Case Reports, Special Session : 3D-Printing In Medicine, Case Reports In Alternative And Traditional Medicine

Download or read book Proceedings of 8th Edition of International Conference on Chemistry Science and Technology 2018 written by EuroScicon and published by EuroScicon. This book was released on 2018-06-01 with total page 70 pages. Available in PDF, EPUB and Kindle. Book excerpt: June 14-15, 2018 London, UK Key Topics : Chemistry Of Compounds, Organic Chemistry And Inorganic Chemistry, Physical And Theoretical Chemistry, Heterocyclic Chemistry, Electrochemistry, Electrolysis And Corrosion, Geochemistry, Nuclear Chemistry/Radiochemistry, Biochemistry, Pharmaceutical/Medicinal Chemistry, Polymer Chemistry, Forensic Chemistry, Environmental Chemistry, Bio Based Chemistry, Analytical Chemistry, Multi-Scale And/Or Multi-Disciplinary Approach To Process-Product Innovation, Sustainable Process-Product Development Through Green Chemistry, ,

Download or read book Progress in Drug Research Fortschritte der Arzneimittelforschung Progr s des recherches pharmaceutiques written by George deStevens and published by Birkhäuser. This book was released on 2013-11-11 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: Contents: V. Zingel, C. Leschke and W. Schunack: Developments in research on histamine (H1) receptor agonists / P.D. Hoeprich: Antifungal chemotherapy / G. de Stevens: The diversity of heterocyclic compounds and their biological activities / R.M. Schultz: Newer antifolate compounds in cancer therapy / P.K. Mehrotra, S. Batra and A.P. Bhadun: Non-steroidal agents for regulation of the menstrual cycle / A.K. Saxena and M. Saxena: Developments in anti-convulsant drugs

Download or read book Proceedings of 8th European Immunology Conference 2017 written by ConferenceSeries and published by ConferenceSeries. This book was released on with total page 123 pages. Available in PDF, EPUB and Kindle. Book excerpt: June 29-July 01, 2017 Madrid, Spain Key Topics : Clinical and Cellular Immunology, Inflammatory/Autoimmune Diseases, T-Cells and B-Cells, Cancer and Tumor Immunobiology, Vaccines and Vaccination, Immunotherapy, Neuro Immunology, Infectious Diseases and Immune System, Reproductive Immunology, Immunodeficiences, Costimmulatory pathways in multiple sclerosis, Autoimmunity and Therapathies, Diagnostic Immunology, Clinical Immunology, Microbial, Parasitic, and Fungal Immunology, Allergy and Therapathies, Technological Innovations in Immunology, Antigen Processing, Hematopoiesis and Immune System Development, Immune Response Regulation, Molecular Mechanisms, Innate Immune Responses, Transplantation Immunology, Viral Immunology, Immunoinformatics and Systems Immunology, Cellular Adhesion, Immunopathology, Mucosal and Regional Immunology,

Download or read book Information Bulletin written by International Union of Pure and Applied Chemistry and published by . This book was released on 1977 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Histamine Receptor written by J. C. Schwartz and published by . This book was released on 1992-01-24 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synthesizes the latest information and research involving the pharmacochemistry, biochemical properties and neurobiological function of histamine receptors. Contains over 50 illustrations.

Download or read book Histamine and Histamine Antagonists written by Börje Uvnäs and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 782 pages. Available in PDF, EPUB and Kindle. Book excerpt: Together with the two previous volumes of the Handbook of Experimental Pharmacology on histamine and antihistamines the present publication yields a picture of a still rapidly developing field of research. New techniques and new experimental approaches have brought us new knowledge and deeper insight into the biomedical significance of histamine, even if many questions remain to be answered about the functional and medical implications of this old biogenic amine. The present volume covers the progress in histamine research during the past two decades. A significant chapter concerns techniques for histamine determination. As the result of a consensus meeting in Munich in December 1988, a panel of eminent specialists arrived at common recommendations as to the usefulness of the available histamine assays for the most common experimental biomedical conditions. The heterogeneity of mast cells, with great differences in their reactivity to various stimuli, has become apparent, not only among species but also among the tissues of a species. New informa tion is presented about the mechanism of exocytosis. The old questions about the role of histamine in the mechanism of gastric secretion and in cardio vascular and respiratory functions have been studied with new techniques, and the role of HI and H2 receptors discussed. New observations have been made on the occurrence and possible functions of histaminergic neurons and histamine receptors in CNS where a new type of receptor, the H , seems to 3 be widely represented.

Download or read book NIDA Research Monograph written by and published by . This book was released on 1976 with total page 764 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Comprehensive Medicinal Chemistry written by Corwin Hansch and published by . This book was released on 1990 with total page 1310 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug design is a multi-disciplinary activity involving chemists, biologists, bochemists, mpharmacologists and many others. the chemist's role is central in inventing new compounds which exert a beneficial effect. However, once a lead for a new active drug has been established, its effective delivery has to be demonstrated and extensive toxikological studies undertaken to demonstrate its safety before cinical trials can commence. The metabolic fate of the drug has to be revealed and detailed distribution studies carried out in order to satisfy the regulatory authorities before the new compound can be marketed. Comprehensive Medicinal Chemistry describes all these aspects of the design of a drug whilst centering on the chemical mechanism whereby such agents act. Volume 2 deals with enzymes and other molecular targets.