Download or read book Veterinary Clinical Trials From Concept to Completion written by Nigel Dent and published by CRC Press. This book was released on 2001-12-31 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: Conceived and edited by Nigel Dent and Ramzan Visanji, Veterinary Clinical Trials form Concept to Completion is designed for both established practitioners and novices, offering alternative ways of conducting studies and ensuring that the studies are guided by Good Clinical Practices and are in compliance with regulations. Comprehensive in scope, it provides the scientific, biological, and regulatory background invaluable to teachers, researchers, and regulatory affairs staff, as well as those directly involved in clinical trials. The book covers: Objectives of the clinical study Control of the study Conduct of the study Regulation versus compliance Factors for success International harmonization activities Roles of the investigator, the monitor, and the practicing veterinarian Setting up GCP trials with particular animal species SOPs, the generic protocol, and the study report Contract research farms and multi-site studies Auditing With contributions from experts in every area of veterinary trials, the text has been organized with everyday use in mind. The chapters can be read sequentially for a comprehensive view or individually for coverage of particular topics and issues as needed. Drawing directly from the in-the-trenches experience of the editors and chapter authors, the book is a guide to methods that ensure studies meet regulatory compliance and strategies that ensure avoidance of common pitfalls.
Download or read book Veterinary Epidemiology written by Michael Thrusfield and published by John Wiley & Sons. This book was released on 2018-04-30 with total page 901 pages. Available in PDF, EPUB and Kindle. Book excerpt: Eine umfassende Einführung zur Rolle der Epidemiologie in der Veterinärmedizin. Die vollständig überarbeitete und erweiterte Ausgabe von Veterinary Epidemiology führt den Leser in das Fachgebiet der Veterinärepidemiologie ein. Diese neue Auflage bietet auch neue Kapitel zur Konzeption von Beobachtungsstudien, Validität von epidemiologischen Studien, zu systematischen Prüfungen und zu statistischen Modellen. Die aktualisierte Auflage beginnt mit einem historischen Blick auf die Entwicklung der Veterinärmedizin. Im Anschluss wird die Fachrichtung Epidemiologie umfassend beleuchtet. Kapitel befassen sich mit den Aspekten Kausalität, Auftreten von Krankheiten, Bestimmungsfaktoren, Krankheitsmustern, Krankheitsökologie u.v.m. Veterinary Epidemiology, 4. Auflage: - Alle Kapitel wurden aktualisiert. Entstanden ist ein modernes Referenzwerk zum Thema Veterinärepidemiologie. - Enthält neue Kapitel, die für die Entwicklung des Fachgebiets maßgeblich sind. - Bietet Beispiele zu Haustieren, Nutztieren und Vögeln sowie zu Krankheiten bei Wassertieren. - Richtet den Fokus auf Prinzipien und Konzepte der Epidemiologie, der Überwachung, der Validierung und Leistungsfähigkeit diagnostischer Tests. - Begleitende Website mit Multiple-Choice-Fragen.
Download or read book Sharing Clinical Trial Data written by Institute of Medicine and published by National Academies Press. This book was released on 2015-04-20 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: Data sharing can accelerate new discoveries by avoiding duplicative trials, stimulating new ideas for research, and enabling the maximal scientific knowledge and benefits to be gained from the efforts of clinical trial participants and investigators. At the same time, sharing clinical trial data presents risks, burdens, and challenges. These include the need to protect the privacy and honor the consent of clinical trial participants; safeguard the legitimate economic interests of sponsors; and guard against invalid secondary analyses, which could undermine trust in clinical trials or otherwise harm public health. Sharing Clinical Trial Data presents activities and strategies for the responsible sharing of clinical trial data. With the goal of increasing scientific knowledge to lead to better therapies for patients, this book identifies guiding principles and makes recommendations to maximize the benefits and minimize risks. This report offers guidance on the types of clinical trial data available at different points in the process, the points in the process at which each type of data should be shared, methods for sharing data, what groups should have access to data, and future knowledge and infrastructure needs. Responsible sharing of clinical trial data will allow other investigators to replicate published findings and carry out additional analyses, strengthen the evidence base for regulatory and clinical decisions, and increase the scientific knowledge gained from investments by the funders of clinical trials. The recommendations of Sharing Clinical Trial Data will be useful both now and well into the future as improved sharing of data leads to a stronger evidence base for treatment. This book will be of interest to stakeholders across the spectrum of research-from funders, to researchers, to journals, to physicians, and ultimately, to patients.
Download or read book Learning from Disease in Pets written by Rebecca A. Krimins and published by CRC Press. This book was released on 2020-11-25 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: Learning from Disease in Pets: A ‘One Health’ Model for Discovery is the first encompassing reference guide for veterinarians, researchers and physicians on conducting studies using spontaneous models of disease in animals. The study of naturally occurring disease in (pet) animals can help model our understanding of the biology, prevention and therapy of human and animal diseases. Studies of pet dogs, for instance, can aid treatment of complex medical problems such as cancer, orthopedic, cardiopulmonary, and neuro-inflammatory diseases, and zoonotic infections. Each chapter within this novel cross-species approach is contributed by a leader, or leaders, in their field of research. Using clinical trials to learn how pets with real diseases respond to therapy can lead to breakthroughs in human medicine, as well as benefiting pets suffering from otherwise debilitating illness. Despite similarities of diseases across species, there are very few spontaneous models of disease used in research compared with models where disease is induced in healthy laboratory animals. Many medical researchers and veterinarians have a multitude of questions regarding how to use naturally occurring diseases in pets for the discovery of treatments and diagnostics: this book will demonstrate how to safely make this happen. This book encourages veterinarians to build on and disseminate existing findings for the wider benefit of pets and humans. Many pets suffering from incurable illnesses may benefit from clinical trials; the book includes a section on the imperative communication styles necessary within the research environment and with clients, a compelling discussion on the ethics of using pets in veterinary clinical research, comprehensive tables of diseases that spontaneously occur in animals and humans, the regulatory requirements necessary to move therapy from benchside research to patient bedside, as well as intricate details on how to design a robust clinical study.
Download or read book Critical Needs for Research in Veterinary Science written by National Research Council and published by National Academies Press. This book was released on 2005-10-18 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research in veterinary science is critical for the health and well-being of animals, including humans. Food safety, emerging infectious diseases, the development of new therapies, and the possibility of bioterrorism are examples of issues addressed by veterinary science that have an impact on both human and animal health. However, there is a lack of scientists engaged in veterinary research. Too few veterinarians pursue research careers, and there is a shortage of facilities and funding for conducting research. This report identifies questions and issues that veterinary research can help to address, and discusses the scientific expertise and infrastructure needed to meet the most critical research needs. The report finds that there is an urgent need to provide adequate resources for investigators, training programs, and facilities involved in veterinary research.
Download or read book Agriculture rural development and related agencies appropriations for 1986 written by United States. Congress. House. Committee on Appropriations. Subcommittee on Agriculture, Rural Development, and Related Agencies and published by . This book was released on 1986 with total page 888 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Cumulated Index Medicus written by and published by . This book was released on 1985 with total page 1106 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Withrow and MacEwen s Small Animal Clinical Oncology written by Stephen J. Withrow and published by Elsevier Health Sciences. This book was released on 2012-11-13 with total page 775 pages. Available in PDF, EPUB and Kindle. Book excerpt: With a unique focus on the most effective interventional techniques, Withrow & MacEwen's Small Animal Clinical Oncology, 5th Edition tells the full story of cancer in dogs and cats - what it is, how to diagnose it, and how to treat many of the most common cancers encountered in clinical practice. Nearly 500 color photographs, diagrams, x-rays, and gross views depict the clinical manifestations of various cancers. This edition covers the latest advances in clinical oncology, including chemotherapy, surgical oncology, and diagnostic techniques. With contributions from 65 veterinary oncology experts, this authoritative reference is a must-have for current, evidence-based therapeutic strategies on canine and feline oncology. "I really love this book. If you are interested in veterinary oncology, have a flick through this book online or at a conference when you get the chance. I hope that you agree with me that this is the definitive oncology reference source for the early 21st century and that you feel compelled to buy it. Your patients will thank you for it." Reviewed by: Gerry Polton MA VetMB MSc(Clin Onc) DipECVIM-CA(Onc) MRCVS, UK Date: July 2014 Cutting-edge information on the complications of cancer, pain management, and the latest treatment modalities prepares you to diagnose and treat pets with cancer rather than refer cases to a specialist. A consistent format for chapters on body system tumors includes coverage of incidence and risk factors, pathology, natural behavior of tumors, history and clinical signs, diagnostic techniques and workup, treatment options, and prognosis for specific malignancies. A systems approach to the diagnosis and management of cancer facilitates access to information about the many malignancies affecting small animal patients. Nearly 500 color images provide accurate depictions of specific diseases and procedures. Helpful drug formularies provide quick access to information on indications, toxicities, and recommended dosages for chemotherapeutic and analgesic drugs used in cancer treatment. Expert contributors provide in-depth coverage of the most current information in his or her respective specialty in veterinary oncology. Chemotherapy protocols are included when case studies prove clinical efficacy. Discussion of compassion and supportive care for the management of pain, nutritional needs, and grief includes methods for handling the pet's pain and nutritional complications as well as the pet owner's grief when treatment is not successful. Thoroughly UPDATED chapters cover the most recent changes in the clinical management of melanoma, mast cell tumors, tumors of the skeletal system, tumors of the endocrine system, tumors of the mammary gland, urinary cancers, nervous system cancers, lymphoma, and histiocytic diseases. NEW Clinical Trials and Developmental Therapeutics chapter discusses the various phases of clinical trials as well as current challenges and opportunities in oncology drug development. NEW! A focus on the best recommended treatment options highlights therapeutic strategies that have been vetted by veterinary oncology experts. NEW co-author Dr. Rodney L. Page adds his valuable perspective, expertise, and research experience.
Download or read book Integrative Veterinary Medicine written by Mushtaq A. Memon and published by John Wiley & Sons. This book was released on 2023-05-31 with total page 293 pages. Available in PDF, EPUB and Kindle. Book excerpt: Integrative Veterinary Medicine Practical guide integrating holistic modalities into Western veterinary practice to help with patient treatment Integrative Veterinary Medicine provides a clinically oriented, evidence-based guide to integrating complementary and conventional therapies into veterinary practice. Covering acupuncture, manual therapies, botanical and herbal medicine, integrative nutrition, and physical rehabilitation, the book draws information on these modalities together into a single resource. Rooted in evidence-based medicine, it demonstrates how to use these modalities in veterinary practice. The book begins by discussing the basic concepts of integrative veterinary medicine, then examines each modality in detail. A companion website offers video clips showing acupuncture techniques. In Integrative Veterinary Medicine, readers can expect to find detailed information on topics such as: Anatomy and physiology of acupuncture with relation to soft tissue and neurologic concepts, and traditional Chinese theory of acupuncture (Yin and Yang, Five Element Theory, and The Meridians) Veterinary manipulative therapy (neurology, biomechanics, and available evidence), and massage therapy and myofascial principles Origins and major systems of herbal therapy with selected evidence-based interventions and adverse events, herb-drug interactions, supplement evaluation, and regulation Trends in nutrition, such as raw diets, home-prepared diets, grain-free diets, owner perception, and current marketing Covering common modalities across all species in one volume, Integrative Veterinary Medicine is an essential reference for any veterinary practitioner wishing to use integrative techniques in their practices, as well as veterinary students, academics, and researchers involved in programs of study related to integrative veterinary medicine.
Download or read book Advances in Veterinary Oncology An Issue of Veterinary Clinics of North America Small Animal Practice written by Annette N. Smith and published by Elsevier Health Sciences. This book was released on 2014-09-28 with total page 217 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue focuses on new advances in oncology in treating dogs and cats. Topics include: Use of metronomic chemotherapy in veterinary cancer patients, Evidence-based integrative medicine in clinical veterinary oncology, The role of surgery in multimodality cancer therapy for small animals, Cancer screening tests for small animals, Antibiotic use in veterinary oncology patients, Tyrosine kinase inhibitors in veterinary oncology practice, Stereotactic radiosurgery/Advances in veterinary radiation therapy, Tumor vaccines in veterinary oncology practice, Chemotherapy safety in clinical veterinary oncology, Role of neutering in cancer development, and more!
Download or read book System Vaccinology written by Vijay Kumar Prajapati and published by Academic Press. This book was released on 2022-08-20 with total page 438 pages. Available in PDF, EPUB and Kindle. Book excerpt: Emergence of new and deadly infectious diseases is significantly deteriorating the human health. Development of vaccine by the scientist has become an important weapon to control the spread of infectious diseases as well as to improve the life expectancy at global level in 20th-21st Century. This book will provide the in-depth knowledge of vaccine history, and development of new strategies to design efficacious and safe vaccine molecule. This book will cover the development of system vaccinology and their applications revolutionize the vaccine discovery. This will provide a resource for the basic and clinical researcher working to human life expectancy by their vaccine experiments and clinical trials. My purpose to write this book to educate the students and researchers with modern development in the field of vaccinology and empowering the researcher with new tools and methodology for developing potential and immunogenic vaccines. This book will be helpful to solve the curiosity of science and medical background students related with vaccinology and will be helpful to devise a new vaccine molecule to control the spread of new and emerging pathogens. Systems biology is a rapidly expanding research discipline aiming to integrate multifaceted datasets generated using state-of-the-art high- throughput technologies such as arrays and next-generation sequencing. Combined with sophisticated computational analysis we are able to interrogate host responses to infections and vaccination on a systems level, thus generating important new hypotheses and discovering unknown associations between immunological parameters. - Provides in-depth knowledge of vaccine history - Covers the development of system vaccinology and their applications revolutionize the vaccine discovery - Gives insights to the development of new strategies to design efficacious and safe vaccine molecule - Provides a resource for the basic and clinical researcher working to human life expectancy by their vaccine experiments and clinical trials - Highlights the importance of differential miRNA expression, microbiome after vaccination for human health - Serves the need of students and researcher for applying computational tools and quick designing of potential molecule which may be proposed for vaccine trial - Take the decisions to perform the kind of experiments for assessment of vaccine immunogenicity - Aims to understand disease pathogenesis and host responses to infection and vaccination - Offers a seamless continuum of scientific discovery and vaccine invention
Download or read book Development and Formulation of Veterinary Dosage Forms written by Gregory E. Hardee and published by CRC Press. This book was released on 2021-04-30 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although the United States (U.S.) and the more developed nations of the remainder of the world are blessed with a variety of pharmaceuticals, feed additives, and biological products to treat, prevent, and control animal diseases, there is a healthy desire among persons involved in animal health issues to increase our animal medicine chest. The interest stems from the desire to efficiently produce food that is safe and plentiful and from the desire to have more and better government-approved products available for the prevention and treatment of diseases of dogs, cats, and horses and for an increasing variety of minor animal species. For the animal health industry, increased drug availability means broader markets, increased revenues, and an opportunity to better serve their customers. For the veterinarian, more animal health products means that he or she is better able to treat the usual and the unusual conditions, and to prevent animal disease and suffering. No doubt, we are all winners when new technology and industrial and regulatory initiatives hasten the availability of safe and effective animal health products.
Download or read book Equine Reproduction written by Angus O. McKinnon and published by John Wiley & Sons. This book was released on 2011-07-05 with total page 3333 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in a much-anticipated two-volume new edition, this gold-standard reference stands as the most comprehensive and authoritative text on equine reproduction. Serving theriogenologists, practitioners and breeders worldwide as a one-stop resource for the reproductive assessment and management of equine patients, Equine Reproduction, Second Edition provides detailed information on examination techniques, breeding procedures, pregnancy diagnosis and management, reproductive tract diseases and surgery, and foaling. A companion website offers hundreds of images from the book in color. For the Second Edition, the stallion, mare and foal sections have been thoroughly updated and revised to include the latest information on every subject. New topics include discussion of nutritional and behavioral factors in the broodmare and stallion, parentage testing, fetal sexing and the health and management of older foals, weanlings and yearlings. Additionally, this outstanding Second Edition features a new section on assisted reproductive techniques, including detailed information on artificial insemination, in-vitro fertilization, embryo transfer and technology.
Download or read book CNS Cancer written by Erwin G. Van Meir and published by Springer Science & Business Media. This book was released on 2009-08-15 with total page 1294 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancers of the central nervous system are among the most lethal of human neoplasms. They are recalcitrant to even intensive multimodality therapies that include surgery, radiotherapy, and chemotherapy. Moreover, especially in children, the consequences of these therapies can itself be devastating and involve serious cognitive and developmental disorders. It is small wonder that such cancers have come under the intense scrutiny of each of the subspecialties of clinical care and investigation as well as attracting some of the best basic research scientists. Their joint efforts are gradually peeling away the mysteries surrounding the genesis and progression of these tumors and inroads are being steadily made into understanding why they resist therapies. This makes it an especially opportune time to assemble some of the best investigators in the field to review the ‘‘state of the art’’ in the various arenas that comprise the assault on CNS tumors. The breadth of this effort by the clinical and basic neuro-oncology community is quite simply amazing. To a large extent, it evolves from the knowledge of the human genome and its regulation that has been hard won over the past two decades.
Download or read book Withrow and MacEwen s Small Animal Clinical Oncology E Book written by David M. Vail and published by Elsevier Health Sciences. This book was released on 2019-07-23 with total page 865 pages. Available in PDF, EPUB and Kindle. Book excerpt: **Selected for Doody's Core Titles® 2024 with "Essential Purchase" designation in Veterinary Medicine** Considered the definitive reference on canine and feline oncology, Withrow & MacEwen's Small Animal Clinical Oncology, 6th Edition focuses on the most effective, cutting-edge techniques. This comprehensive textbook gives you a complete understanding of cancer in dogs and cats — what it is, how to diagnose it, and how to treat many of the most common cancers encountered in clinical practice today. The thoroughly updated sixth edition includes information on the complications of cancer, pain management, and the latest treatment modalities — preparing general practitioners to diagnose and treat pets rather than referring them to a specialist. With important updates on recently approved and in-development drugs, and new co-authors adding their own unique perspectives, this user-friendly text is a must-have resource for current, evidence-based therapeutic strategies on canine and feline oncology. - Cutting-edge information on the complications of cancer, pain management, and the latest treatment modalities prepares you to diagnose and treat pets with cancer rather than refer cases to a specialist. - Each contributor is a recognized expert in his or her specialty, reflecting the most current information by highly respected experts in the field of veterinary oncology. - Full-color format provides you with accurate visual depictions of specific diseases and procedures, enhances visual appeal, and is used functionally in tables and boxes to highlight key information. - A systems approach to the diagnosis and management of cancer facilitates access to information about the many malignancies affecting small animal patients. - Discussion of compassion and supportive care for the management of pain, nutritional needs, and grief includes methods for handling the pet's pain and nutritional complications as well as the pet owner's grief when treatment is not successful. - Comprehensive references at the end of each chapter and topic ensures you can be confident the information provided is accurate and up to date. - Helpful drug formularies provide quick access to information on indications, toxicities, and recommended dosages for chemotherapeutic and analgesic drugs used in cancer treatment. - Chemotherapy protocols are included when case studies prove clinical efficacy. - Information on the best interventional techniques is quickly accessible all in one chapter. - Nearly 400 color images provide accurate depictions of specific diseases and procedures. - Focus on the most effective treatment options saves time by emphasizing proven treatment options that have been vetted by experts in the field. - NEW! Expert co-authors and contributors bring a valuable perspective with research experience. - NEW! Thoroughly UPDATED content includes important updates on recently approved and in-development veterinary cancer drugs, and critical advances in radiation delivery.
Download or read book Small Animal Clinical Pharmacology and Therapeutics written by Dawn Merton Boothe and published by Elsevier Health Sciences. This book was released on 2011-04-05 with total page 1349 pages. Available in PDF, EPUB and Kindle. Book excerpt: Confidently utilize the rapidly growing selection of pharmaceuticals used to treat small animals. Small Animal Pharmacology and Therapeutics, 2nd Edition helps you understand both the therapeutic uses of common pharmaceuticals and the pharmacology behind them, giving you all of the information you need to design and modify dosing regimens, identify factors that cause drugs to fail, and anticipate adverse drug reactions. Comprehensive approach emphasizes the use of drugs for prevention as well as treatment. Clear, consistent organization makes it easy to find the information you need when you need it. Dosage tables help you find essential pharmaceutical information at a glance. Pharmacogenetics chapter helps you understand how to use this emerging science to find the right dose for each patient, optimizing efficiency and minimizing toxicity. Routes of administration and sample pharmaceutical calculations provide fast, efficient access to comprehensive drug administration all in one inclusive resource. Multiple chapters on Antimicrobial Drugs and Antimicrobial Therapy highlight the impact of antimicrobial resistance on current practice.
Download or read book The Complete Guide To Herbal Medicines written by Charles W. Fetrow and published by Simon and Schuster. This book was released on 2000-09 with total page 720 pages. Available in PDF, EPUB and Kindle. Book excerpt: Each herbal medicine entry contains information on why people use the herb, what the research shows, common doses, side effects, interactions with drugs, important points to remember, and references to scientific studies.
