Download or read book Vascular Protection written by Gabor M. Rubanyi and published by CRC Press. This book was released on 2002-02-21 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vascular Protection explores advances in vascular biology and how they translate into innovations in drug therapy for vascular disease. It addresses recent advances in the knowledge of endothelial vasoactive factors and other biologically active molecules as well as gene therapy. Written by leading experts in their respective fields, each chapter e
Download or read book Early Vascular Aging EVA written by Pedro Guimarães Cunha and published by Elsevier. This book was released on 2024-02-29 with total page 772 pages. Available in PDF, EPUB and Kindle. Book excerpt: Early Vascular Aging (EVA): New Directions in Cardiovascular Protection, Second Edition continues to be the most comprehensive and authoritative resource on premature alterations in artery structure and function. The book presents a novel approach to the problem of cardiovascular disease, showing it in relation to great vessels disease and revealing a comprehensive approach to the problem of increased rigidity of the great vessels, its causes, and further consequences. This second edition contains completely updated content with expanded coverage of basic and translational research, systematic reviews of the most prominent literature, discussion of applicability of new evidence and more. Written by an international team of clinicians and researchers, this is a valuable resource to basic and translational scientists, clinical researchers and clinicians in the cardiovascular field interested in prevention, diagnosis and treatment of EVA. Contains all the relevant information available on the main paradigm shifts in vascular aging research, from different fields of knowledge (from basic biology to epidemiology) Reviews the most prominent evidence produced on early vascular aging (EVA), highlighting recent research advances, clinical applications, and research opportunities Formulates, in each chapter, a set of research questions that need to be addressed, challenging the vast research community to take on new directions and collaborations
Download or read book Vascular Protection written by Gabor M. Rubanyi and published by CRC Press. This book was released on 2002-02-21 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vascular Protection explores advances in vascular biology and how they translate into innovations in drug therapy for vascular disease. It addresses recent advances in the knowledge of endothelial vasoactive factors and other biologically active molecules as well as gene therapy. Written by leading experts in their respective fields, each chapter emphasizes the mechanisms and pathologic consequences of vascular disorders, highlighting the clinical ramifications of these insights and the potential for new therapeutic strategies. Vascular Protection provides critical new information for researchers and clinicians, as well as to industrial scientists in pursuit of novel therapies for cardiovascular disorders.
Download or read book Vascular Protection written by Gabor M. Rubanyi and published by CRC Press. This book was released on 2002-02-21 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vascular Protection explores advances in vascular biology and how they translate into innovations in drug therapy for vascular disease. It addresses recent advances in the knowledge of endothelial vasoactive factors and other biologically active molecules as well as gene therapy. Written by leading experts in their respective fields, each chapter e
Download or read book Vascular Protection written by Gabor Rubanyi and published by Harwood Academic Publishers. This book was released on 2001-08 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Cerebral Circulation written by Marilyn J. Cipolla and published by Biota Publishing. This book was released on 2016-07-28 with total page 82 pages. Available in PDF, EPUB and Kindle. Book excerpt: This e-book will review special features of the cerebral circulation and how they contribute to the physiology of the brain. It describes structural and functional properties of the cerebral circulation that are unique to the brain, an organ with high metabolic demands and the need for tight water and ion homeostasis. Autoregulation is pronounced in the brain, with myogenic, metabolic and neurogenic mechanisms contributing to maintain relatively constant blood flow during both increases and decreases in pressure. In addition, unlike peripheral organs where the majority of vascular resistance resides in small arteries and arterioles, large extracranial and intracranial arteries contribute significantly to vascular resistance in the brain. The prominent role of large arteries in cerebrovascular resistance helps maintain blood flow and protect downstream vessels during changes in perfusion pressure. The cerebral endothelium is also unique in that its barrier properties are in some way more like epithelium than endothelium in the periphery. The cerebral endothelium, known as the blood-brain barrier, has specialized tight junctions that do not allow ions to pass freely and has very low hydraulic conductivity and transcellular transport. This special configuration modifies Starling's forces in the brain microcirculation such that ions retained in the vascular lumen oppose water movement due to hydrostatic pressure. Tight water regulation is necessary in the brain because it has limited capacity for expansion within the skull. Increased intracranial pressure due to vasogenic edema can cause severe neurologic complications and death.
Download or read book The Endothelium written by Michel Félétou and published by Morgan & Claypool Publishers. This book was released on 2011 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: The endothelium, a monolayer of endothelial cells, constitutes the inner cellular lining of the blood vessels (arteries, veins and capillaries) and the lymphatic system, and therefore is in direct contact with the blood/lymph and the circulating cells. The endothelium is a major player in the control of blood fluidity, platelet aggregation and vascular tone, a major actor in the regulation of immunology, inflammation and angiogenesis, and an important metabolizing and an endocrine organ. Endothelial cells controls vascular tone, and thereby blood flow, by synthesizing and releasing relaxing and contracting factors such as nitric oxide, metabolites of arachidonic acid via the cyclooxygenases, lipoxygenases and cytochrome P450 pathways, various peptides (endothelin, urotensin, CNP, adrenomedullin, etc.), adenosine, purines, reactive oxygen species and so on. Additionally, endothelial ectoenzymes are required steps in the generation of vasoactive hormones such as angiotensin II. An endothelial dysfunction linked to an imbalance in the synthesis and/or the release of these various endothelial factors may explain the initiation of cardiovascular pathologies (from hypertension to atherosclerosis) or their development and perpetuation. Table of Contents: Introduction / Multiple Functions of the Endothelial Cells / Calcium Signaling in Vascular Cells and Cell-to-Cell Communications / Endothelium-Dependent Regulation of Vascular Tone / Conclusion / References
Download or read book Cutting Edge Approaches for CNS Protection and Repair Focus on Vascular and Degenerative Disorders written by Johannes Boltze and published by Frontiers Media SA. This book was released on 2021-08-19 with total page 1044 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Microcirculation in Cardiovascular Diseases written by Enrico Agabiti-Rosei and published by Springer Nature. This book was released on 2020-10-03 with total page 215 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers an extensive review of the most recent data on the pathophysiological role of structural and functional alterations in the microcirculation, particularly focusing on hypertension and diabetes. It covers several relevant and innovative aspects, including the possible mechanisms involved in the development of microvascular remodeling and rarefaction, the technical approaches available for the detection of microvascular alterations, including non-invasive evaluations, the prognostic role of changes in small resistance artery structure, the possibility of preventing or regressing such alterations with appropriate treatment, and the potential clinical advantages of such intervention. A number of innovative areas of research are considered, including the role of the immune system, inflammation and oxidative stress in the development of microvascular alterations. Lastly, it examines the availability of recent non-invasive methods for the evaluation of small resistance artery morphology in the retina, which in the near future may provide a useful tool for the stratification of cardiovascular risk and even for clinical decisions regarding drug treatment, thus providing physicians with a clinically relevant instrument for improving and optimizing the management of hypertensive and diabetic patients. The book provides valuable, clinically relevant information for specialists (cardiology, internal medicine, and endocrinology) and general practitioners, and also offers novel and stimulating data to basic and clinical researchers.
Download or read book Regulation of Tissue Oxygenation Second Edition written by Roland N. Pittman and published by Biota Publishing. This book was released on 2016-08-18 with total page 117 pages. Available in PDF, EPUB and Kindle. Book excerpt: This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere and transports it by diffusion from the air in the alveoli to the blood flowing through the pulmonary capillaries. The cardiovascular system then moves the oxygenated blood from the heart to the microcirculation of the various organs by convection, where oxygen is released from hemoglobin in the red blood cells and moves to the parenchymal cells of each tissue by diffusion. Oxygen that has diffused into cells is then utilized in the mitochondria to produce adenosine triphosphate (ATP), the energy currency of all cells. The mitochondria are able to produce ATP until the oxygen tension or PO2 on the cell surface falls to a critical level of about 4–5 mm Hg. Thus, in order to meet the energetic needs of cells, it is important to maintain a continuous supply of oxygen to the mitochondria at or above the critical PO2 . In order to accomplish this desired outcome, the cardiorespiratory system, including the blood, must be capable of regulation to ensure survival of all tissues under a wide range of circumstances. The purpose of this presentation is to provide basic information about the operation and regulation of the cardiovascular and respiratory systems, as well as the properties of the blood and parenchymal cells, so that a fundamental understanding of the regulation of tissue oxygenation is achieved.
Download or read book Vessel Health and Preservation The Right Approach for Vascular Access written by Nancy L. Moureau and published by Springer. This book was released on 2019-06-10 with total page 303 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Open access book offers updated and revised information on vessel health and preservation (VHP), a model concept first published in poster form in 2008 and in JVA in 2012, which has received a great deal of attention, especially in the US, UK and Australia. The book presents a model and a new way of thinking applied to vascular access and administration of intravenous treatment, and shows how establishing and maintaining a route of access to the bloodstream is essential for patients in acute care today. Until now, little thought has been given to an intentional process to guide selection, insertion and management of vascular access devices (VADs) and by default actions are based on crisis management when a quickly selected VAD fails. The book details how VHP establishes a framework or pathway model for each step of the patient experience, intentionally guiding, improving and eliminating risk when possible. The evidence points to the fact that reducing fragmentation, establishing a pathway, and teaching the process to all stakeholders reduces complications with intravenous therapy, improves efficiency and diminishes cost. As such this book appeals to bedside nurses, physicians and other health professionals.
Download or read book Mechanisms of Vascular Disease written by Robert Fitridge and published by University of Adelaide Press. This book was released on 2011 with total page 589 pages. Available in PDF, EPUB and Kindle. Book excerpt: New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.
Download or read book Complications in Peripheral Vascular Interventions written by Martin Schillinger and published by CRC Press. This book was released on 2007-05-31 with total page 954 pages. Available in PDF, EPUB and Kindle. Book excerpt: Increasing evidence suggests that particularly in high-risk patients, endovascular solutions offer substantial advantages compared to vascular surgical procedures. Nevertheless, growing numbers of procedures are associated with an increased incidence of complications. Knowledge of specific complications in different vessel areas will support the interventionist in preventing such adverse events and if necessary, provide considerable reassurance if such complications need to be resolved. In Complications in Peripheral Vascular Interventions, typical and atypical complications are described for all peripheral vessel areas, and methods for how to handle these events are outlined. The book is divided in two parts. Part 1 reviews general aspects on complications in peripheral interventions, and Part II covers the specific vessel areas. Each chapter on the specific vessel area includes Introduction to the frequency and kind of complications in this vessel area Factors identifying high-risk patients for these complications Complications of specific interventional steps and tools Endovascular techniques to resolve these complications Methods to avoid complications Summary Checklist for emergency equipment Offering practical tips for the interventionist in the cath lab, high-volume interventionists share their experiences by reviewing complicated cases and outlining different strategies used in real-life scenarios.
Download or read book Rutherford s Vascular Surgery E Book written by Jack L. Cronenwett and published by Elsevier Health Sciences. This book was released on 2014-03-12 with total page 3288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Published in association with the Society for Vascular Surgery, Rutherford’s Vascular Surgery presents state-of-the-art updates on all aspects of vascular health care. Extensively revised by many new authors to meet the needs of surgeons, interventionalists, and vascular medicine specialists, this medical reference book incorporates medical, endovascular and surgical treatment, as well as diagnostic techniques, decision making and fundamental vascular biology. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Master the latest developments, techniques, and approaches with thorough updates on endovascular applications, vascular access, imaging, non-operative management, and much more. View clinical and physical findings and operative techniques more vividly with a full-color layout and images. Get answers you can depend on. Rutherford's delivers the world’s most trusted information on all major areas of vascular health care, is written by international experts, and includes up-to-date bibliographies and annotated recommended references. Discover emerging techniques in rapidly advancing topics, with special emphasis on endovascular coverage, vascular imaging, angiography, CT and MRI. Explore brand new chapters on dialysis catheters, renovascular disease, and management of branches during endovascular aneurysm. Stay up-to-date with the latest coverage of endovascular procedures that reflects the changing practices and techniques in vascular surgery. Access videos at Expert Consult.
Download or read book Vascular Imaging and Intervention written by Ducksoo Kim and published by Jaypee Brothers Medical Publishers. This book was released on 2019-10-31 with total page 1972 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive guide to vascular imaging and endovascular interventions. Covers diagnosis and treatment of numerous vascular disorders. Internationally recognised author team.
Download or read book Emergent Vascular Access written by James H. Paxton and published by Springer Nature. This book was released on 2021-09-02 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on the placement of vascular access devices under emergent conditions, including the techniques and devices needed to achieve successful device deployment in even the most critically-ill patient. Up-to-date references and evidence for best practices are provided, informing both the novice and experienced healthcare provider. Each chapter is meticulously researched, including individual chapters focusing upon peripheral intravenous, intraosseous, central venous, and ultrasound-guided catheter placement. Device selection and emergent decision-making are discussed at length, including such crucial determinants as infusion flow rates, device limitations, issues with medication incompatibility, complications of line placement, and the relative indications and contraindications associated with various vascular access approaches. Emergent Vascular Access is an essential resource for any healthcare provider who places or manages vascular access devices in critically-ill patients, including emergency and ICU physicians, residents, rapid response providers, EMS paramedics, patient care technicians, medical students, and nurses.
Download or read book Vascular and Endovascular Surgery E Book written by Wesley S. Moore and published by Elsevier Health Sciences. This book was released on 2012-11-23 with total page 1282 pages. Available in PDF, EPUB and Kindle. Book excerpt: Master everything you need to know for certification, recertification, and practice with Vascular and Endovascular Surgery: A Comprehensive Review, 8th Edition. From foundational concepts to the latest developments in the field, Dr. Wesley Moore and a team of international experts prepare you to succeed, using an easy-to-read, user-friendly format and hundreds of review questions to promote efficient and effective study. Consult this title on your favorite e-reader with intuitive search tools and adjustable font sizes. Elsevier eBooks provide instant portable access to your entire library, no matter what device you're using or where you're located. Benefit from the experience of prominent specialists, each of whom provides a complete summary of a particular area of expertise. Visualize key techniques and anatomy thanks to hundreds of easy-to-follow illustrations, including line drawings, CT scans, angiograms, arteriograms, and photographs. Get up to speed with the most recent practices and techniques in vascular diagnosis, peripheral arterial disease, aortic aneurysms/aortic dissection, visceral aneurysms, lower extremities/critical limb ischemia, infra-inguinal occlusive disease, and more - with 16 brand-new chapters and expanded and updated information throughout. Refresh your knowledge with comprehensive coverage that reflects the increasingly important role of endovascular procedures. Access the entire text and illustrations online at www.expertconsult.com, as well as video clips that demonstrate Intra Cranial Lysis of MCA Embolus; Mobile Thrombus in the Carotid Artery; Selective Catheterization, Placement of Protection Filter and PTA/Stenting of the Carotid Artery; and Watermelon Seeding of the Balloon.
