Download or read book Tissue Engineered Vascular Grafts written by Beat H. Walpoth and published by Springer. This book was released on 2020-08-21 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cardiovascular diseases are still the leading cause of death in developed countries. Revascularization procedures such as coronary artery and peripheral bypass grafts, as well as access surgery represent a 2$ billion market yearly for the US alone. Despite intense research over many decades, no clinically suitable, shelf-ready, synthetic, vascular, small-caliber graft exists. There is therefore still a quest for such a clinical vascular prosthesis for surgical revascularization procedures and access surgery. Many approaches have been tried and are currently under investigation with promising results. These range from acellular and cell-based, stable or bio-degradable, synthetic scaffolds to biological or decellularized grafts, not forgetting self-assembly technologies for in vitro or in vivo VTE. All these approaches can be further enhanced by functionalization, e.g. with growth factors and drug elution. This updatable book aims to cover all the relevant aspects of Vascular Tissue Engineering (VTE) and novel alternatives to develop vascular grafts for clinical applications. The chapters in this book cover different aspects of manufacturing scaffolds with various polymers, mechanical characteristics, degradation rates, decellularization techniques, cell sheet assembly, 3-D printing and autologous mandril-based VTE. All the necessary in vitro tests such as biocompatibility and thrombogenicity are reviewed. Pre-clinical assessment of in vivo experimental models include patency, compliance, intimal hyperplasia, inflammatory reaction, cellular ingrowth and remodeling. Finally, early clinical trials will be periodically updated regarding results, regulatory aspects and post-marketing quality assessment. Furthermore, the reader should get an insight into various approaches, technologies and methods to better understand the complexity of blood surface and cell interactions in VTE. Translational research has yielded early human applications clearly showing the enormous need of research in the field to provide better solutions for our patients and this continuously updated book will hopefully become a reference in the field for life sciences.
Download or read book Mechanisms of Vascular Disease written by Robert Fitridge and published by University of Adelaide Press. This book was released on 2011 with total page 589 pages. Available in PDF, EPUB and Kindle. Book excerpt: New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.
Download or read book Vascular Graft Infections written by TJ Bunt and published by Wiley-Blackwell. This book was released on 1994-09-27 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vascular graft infection is a complex and challenging problem for the vascular surgeon. Despite significant advances that have been made in managing patient problems associated with graft infection during the last 25 years, the topic of vascular graft infection has been only loosely covered in various textbooks. Fortunately, this monograph fills this void of information by offering a wealth of useful, clearly organized clinical knowledge
Download or read book Vascular Reconstructions written by Jamal J. Hoballah and published by Springer Science & Business Media. This book was released on 2000-06-16 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: This must-have manual for surgical residents and vascular surgery trainees is copiously illustrated with more than 250 original line drawings. The author presents in a step-by-step fashion the techniques for all common vascular reconstructions, basics of exposure and access, as well as invaluable technical pearls and tips. The text provides the surgical trainee with the opportunity to review and practice the necessary vascular reconstructions before entering the operating room. The illustrations and clear instructions make this a manual that is referred to again and again throughout the surgical residency.
Download or read book Decellularized Extracellular Matrix written by Takashi Hoshiba and published by Royal Society of Chemistry. This book was released on 2019-12-05 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Using this book, the reader will gain a good foundation to the field complemented with a broad overview of characterisation, microfabrication and applications.
Download or read book Bioreactors for Tissue Engineering written by Julian Chaudhuri and published by Springer Science & Business Media. This book was released on 2006-01-16 with total page 373 pages. Available in PDF, EPUB and Kindle. Book excerpt: For the first time in a single volume, the design, characterisation and operation of the bioreactor system in which the tissue is grown is detailed. Bioreactors for Tissue Engineering presents an overall picture of the current state of knowledge in the engineering of bioreactors for several tissue types (bone, cartilage, vascular), addresses the issue of mechanical conditioning of the tissue, and describes the use of techniques such as MRI for monitoring tissue growth. This unique volume is dedicated to the fundamentals and application of bioreactor technology to tissue engineering products. Not only will it appeal to graduate students and experienced researchers in tissue engineering and regenerative medicine, but also to tissue engineers and culture technologists, academic and industrial chemical engineers, biochemical engineers and cell biologists who wish to understand the criteria used to design and develop novel systems for tissue growth in vitro.
Download or read book Arterial Grafting for Coronary Artery Bypass Surgery written by Guo-Wei He and published by Springer Science & Business Media. This book was released on 2006-08-25 with total page 349 pages. Available in PDF, EPUB and Kindle. Book excerpt: This updated edition examines the biological characteristics and clinical use of arterial grafts for coronary artery bypass surgery. It contains first-hand information on arterial grafts, as well as vein grafts with regard to biological characteristics, clinical use including off-pump coronary bypass grafting surgery, results, and future developments. The book is a practical guide and as a stimulus for further improvement of arterial grafting techniques.
Download or read book Vascular Tissue Engineering written by Feng Zhao and published by Humana. This book was released on 2021-10-01 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume explores the latest techniques used to study the field of tissue engineered vascular grafts (TEVGs). The chapters in this book cover a wide array of topics such as deriving vascular cells from monocytes and induced pluripotent stem cells; engineering vascular grafts using various biomaterials and stem cells, stem cell-derived, or primary vascular cells; biomaterial modification by anticoagulation molecules; vascular bioengineering technologies such as 3D bioprinting; and fabrication of TEVGs with different geometry and multiphase structures. This book also features protocols for grafting and evaluation of vascular grafts in animal models, vascular imaging in animals, and the quantification of blood vessel permeability. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and practical, Vascular Tissue Engineering: Methods and Protocols is a valuable resource for biomedical engineers, cell biologists, vascular surgeons, doctors, and nurses.
Download or read book Arteriovenous Access Surgery written by Hans Scholz and published by Springer. This book was released on 2014-11-07 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers a comprehensive overview of up-to-date knowledge on vascular access surgery. Written by a senior author with more than 30 years of experience and by expert contributors, it covers both surgical and theoretical aspects. The author shares his expertise in a hands-on approach and presents his views on the difficulties that every clinician may encounter. The various options for vascular access creation are carefully reviewed. Detailed descriptions and numerous accompanying illustrations of AV fistulas, AV prosthetic grafts, and arterio arterial grafts are provided, and a chapter is also devoted to the use of central venous catheters. Potential complications and their management are explained, and advice is offered on how to deal with special patient groups requiring extra attention. Separate chapters on fluid dynamics (drawing on the author’s own research) and vascular pathology cater for the needs of those with a particular interest in the pathophysiological principles.
Download or read book Molecular Mechanism of Congenital Heart Disease and Pulmonary Hypertension written by Toshio Nakanishi and published by Springer Nature. This book was released on 2020-02-28 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book focuses on the molecular mechanism of congenital heart disease and pulmonary hypertension, offering new insights into the development of pulmonary circulation and the ductus arteriosus. It describes in detail the molecular mechanisms involved in the development and morphogenesis of the heart, lungs and ductus arteriosus, covering a range of topics such as gene functions, growth factors, transcription factors and cellular interactions, as well as stem cell engineering technologies. The book also presents recent advances in our understanding of the molecular mechanism of lung development, pulmonary hypertension and molecular regulation of the ductus arteriosus. As such, it is an ideal resource for physicians, scientists and investigators interested in the latest findings on the origins of congenital heart disease and potential future therapies involving pulmonary circulation/hypertension and the ductus arteriosus.
Download or read book Nanotechnology in Tissue Engineering and Regenerative Medicine written by Ketul Popat and published by CRC Press. This book was released on 2010-11-22 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although nanotechnology applied to medicine has a potentially huge impact on drug delivery and tissue engineering, significant challenges need to be resolved before clinically viable nanomedicine or nanobiomedicine therapies will be available. Skillfully edited, with contributions from an expert panel of researchers, Referred to as "nanomedicine" or "nanobiomedicine," the application of nanotechnology to medicine can impact diagnosis, monitoring, and treatment of diseases, as well as the control and understanding of biological systems. Bringing together an unparalleled field of experts, this volume explores various aspects of nanotechnology and its applications in biomedical fields. The book uses an application-oriented approach to relate laboratory-based research to the development of technologies that are easily adaptable to an industry environment, focusing chiefly on drug delivery, tissue engineering, and regenerative medicine.
Download or read book Integrated Biomaterials in Tissue Engineering written by Murugan Ramalingam and published by John Wiley & Sons. This book was released on 2012-04-02 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book acts as a self-contained resource for understanding the current technological advancement of biomaterials towards tissue engineering applications. It covers impact of biomaterials at different length scales such as macro/micro/nano/ level and offers extensive discussion on cell-biomaterial interactions with illustrative examples. This resource offer a multi-disciplinary approach for the adaptability of integrated biomaterials in tissue repair and reconstruction.
Download or read book Endovascular Aortic Repair written by Gustavo S. Oderich and published by Springer. This book was released on 2017-03-16 with total page 747 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text provides a comprehensive, state-of-the art review of complex endovascular aortic techniques. It will serve as a valuable resource for vascular and cardiovascular surgeons, interventionalists, cardiologists, clinicians, bioengineers and researchers with an interest in complex aortic diseases. The book reviews imaging modalities, diagnostic work up and novel endovascular approaches. Technical aspects are provided by experts in the field, with over 600 illustrations and photographs of key steps for each type of procedure. Results of epidemiologic studies and national databases are summarized, as well as large institutional experiences. An evidence-based approach is used for recommendations regarding best therapies. Other highlights of this unique text include: A new, state-of-the-art review on fenestrated, branched and parallel stent-graft techniques from procedure planning to stent design and implantation. A text dedicated to a topic that has been increasingly recognized by vascular specialists as a priority area in aortic management. An updated overview of current designs and future developments. Special attention to technical details of the procedures with use of illustrations. Technical tips on how to get out of problems during these challenging procedures. Endovascular Aortic Repair: Current Techniques with Fenestrated, Branched and Parallel Stent-Grafts will serve as a very useful resource for physicians and researchers dealing with and interested in complex aortic diseases. It will provide a concise yet comprehensive summary of the current status of the field that will help guide patient management and stimulate investigative efforts. All chapters are written by experts in their fields and include the most up to date scientific and clinical information.
Download or read book Vascular Mechanics and Pathology written by Mano J. Thubrikar and published by Springer Science & Business Media. This book was released on 2007-01-06 with total page 515 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of the book is to bring the two disciplines - vascular mechanics and pathology - together. In addition, the book bridges the gap in our knowledge and enhances engineering applications in medicine. This cutting-edge work presents the use of veins as arterial grafts and discusses the role of vein valves in graft stenosis. The book illustrates aneurysm formation, growth, and rupture, using pressure vessel principles. This new work details the investigation of, amongst other topics, aortic dissection, showing for the first time that the aortic root mechanics plays a vital role in the development of this pathology.
Download or read book Deep Sternal Wound Infections written by Raymund E. Horch and published by Springer. This book was released on 2017-01-19 with total page 139 pages. Available in PDF, EPUB and Kindle. Book excerpt: This concise and practical handbook covers the basics of pathophysiology, diagnosis, interdisciplinary surgical management, prevention and rehabilitation of patients with deep sternal wound infections and sternal osteomyelitis. All relevant aspects and surgical procedures are explained in an easily understandable way. Additionally special approaches and preventive measures are highlighted with regard to the perioperative handling as well as the rehabilitation possibilities. Through concise texts with numerous illustrations, the book is ideal for the practice and as a supplement to further studies. This book is suitable for all specialists who are involved into the treatment and diagnosis of sternal wound infections, particularly cardio-thoracis, thoracic, plastic, vascular surgeons, cardiologists, radiologists, and rehabilitation physicians.
Download or read book Vascular Engineering written by Kazuo Tanishita and published by Springer. This book was released on 2016-03-17 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the fundamental biology and mechanics of the vasculature and examines how this knowledge has underpinned the development of new clinical modalities, including endovascular treatment and vascularization of reconstructed tissue for regenerative medicine. Vascular engineering is a multidisciplinary field integrating vascular biology, hemodynamics, biomechanics, tissue engineering, and medicine. Each chapter offers insights into the dynamics of the circulatory system and explains how the impact of related disease conditions — atherosclerosis, hypertension, myocardial ischemia, and cerebral infarction — has generated a focus on developing expertise to both maintain and treat the vascular system. As a comprehensive book in this expanding area, Vascular Engineering serves as a valuable resource for clinicians as well as academics and professionals working in biophysics, biomedical engineering, and nano and microrheology. Graduate students in these subject areas will also find this volume insightful.
Download or read book Mechanisms of Vascular Disease written by Robert Fitridge and published by Springer Nature. This book was released on 2020-07-30 with total page 739 pages. Available in PDF, EPUB and Kindle. Book excerpt: This extensively revised third edition provides a practically applicable guide to the pathophysiology, assessment and management of vascular disorders encountered in vascular surgical practice. It features detailed information on the latest developments in the pathophysiology of conditions including atherosclerosis, multi-organ failure, limb compartment syndromes and Raynaud’s phenomenon in a clear easy to digest format. Disorders such as reperfusion injuries, vasculitides, and aortic dissection are covered. Furthermore, key topics in vascular and endovascular practice such as radiation biology and radiation safety are also detailed. Each chapter contains a set of learning objectives and key references, enabling the reader to quickly identify key points. Mechanisms of Vascular Disease: A Textbook for Vascular Specialists comprehensively covers a variety of common and unusual pathophysiologies encountered in vascular surgery, and is an ideal resource for both the trainee, and practicing clinical vascular surgeon seeking an up-to-date resource on the topic.
