Download or read book Use of Glucosamine Chondroitin and Omega 3 Fatty Acid Supplements in Relation to Inflammation and Risk of Colorectal Cancer written by Elizabeth D. Kantor and published by . This book was released on 2012 with total page 129 pages. Available in PDF, EPUB and Kindle. Book excerpt: In a prior exploratory analysis conducted within the VITamins and Lifestyle (VITAL) cohort study, we observed that use of glucosamine, chondroitin, and omega-3 polyunsaturated fatty acid (omega-3 PUFA)-containing fish oil supplements was associated with decreased risk of colorectal cancer (CRC) after 5 years of follow-up. With an additional 2 years of follow-up in the VITAL cohort, we have examined these associations in more detail among 77,719 adults aged 50-76, and have explored the biologic mechanisms by which these supplements may reduce CRC risk. Data on 220 VITAL biomarker study participants was used to test whether use of glucosamine, chondroitin, and fish oil supplements is associated with oxidative stress, DNA damage, and DNA repair capacity. Additionally, we have used data from the National Health And Nutrition Examination Survey (NHANES) to evaluate the association between use of these supplements and inflammation among 9,947 adults aged 25 and older. Persons reporting use of glucosamine+chondroitin on 4+ days/week for 3+ years had 45% lower risk of CRC than non-users [Hazard Ratio (HR): 0.55; 95% CI: 0.30-1.01; p-trend: 0.16]. This association varied by body mass index (p-interaction: 0.006), with a significant inverse association observed among the overweight/obese only. As compared to non-use, high use of fish oil supplements (4+ days/week for 3+ years) was associated 49% reduced of CRC (HR: 0.51; 95% CI: 0.26-1.00; p-trend: 0.06). The association between fish oil use and decreased risk of CRC was primarily observed among men (p-interaction: 0.02), and for cancers of the colon rather than cancers of the rectum (p-difference: 0.05). We also examined the associations between omega-3 PUFAs, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), and CRC, as well as between dark fish consumption and CRC. While total (diet+supplementary) EPA+DHA intake and dark fish consumption were not associated with CRC overall, these associations were modified by underlying genetic risk (p-interaction: 0.009 and 0.02, respectively): significant inverse associations were observed among persons of low and moderate genetic risk, while positive associations were observed among persons of high genetic risk. Glucosamine and chondroitin supplements were also observed to be associated with reduced oxidative stress, as measured by prostaglandin 2 alpha (p-trend: 0.01 and p-trend: 0.003, respectively) and reduced inflammation, as measured by high-sensitivity C-reactive protein (hsCRP). Persons reporting use of glucosamine supplements experienced 17% lower hsCRP than non-users (0.83; 95% CI: 0.74-0.93), while chondroitin users had 22% lower hsCRP than non-users (0.78; 95% CI: 0.67-0.92). However, use of glucosamine and chondroitin supplements was not associated with DNA damage, DNA repair, or 8-isoprostane, another measure of oxidative stress. Fish oil supplement use was associated with reduced hsCRP (ratio: 0.84; 95% CI: 0.71-1.00), but not with measures of oxidative stress/DNA damage. Our findings suggest that use of glucosamine, chondroitin, and fish oil supplements may be associated with a reduced risk of CRC and offer plausible biologic mechanisms to support these observed associations. CRC poses a substantial health burden in the United States, and there is great need to identify safe and effective preventives. Further research will be needed to better understand the chemopreventive potential of these supplements.
Download or read book The Health Benefits of Omega 3 Fatty Acids in Inflammatory Bowel Disease and Irritable Bowel Syndrome written by Maria Martin and published by Lulu.com. This book was released on 2012-06-16 with total page 116 pages. Available in PDF, EPUB and Kindle. Book excerpt: Omega-3 fatty acids are known to be beneficial supplements and can benefit one's health. This book is an updated thesis that was presented to Clayton College of Natural Health in 2004 and discusses the benefits of omega-3 fatty acids in inflammatory bowel disease and irritable bowel syndrome. In addtion to explaining what these substances are and how they work in the human body, actual studies are discussed that show the benefits that these fatty acids may have in cases of IBD and IBS. Anti-inflammatory properties as well as changes in serotonin signalling with the use of omega-3's are discussed as well as the dangers of taking medications for these disorders. The omega-3 fatty acids have been shown to have many benefits in inflammatory conditions and may be useful supplements in the treatment of these digestive disorders.
Download or read book Dietary Omega 3 Polyunsaturated Fatty Acids and Cancer written by Gabriella Calviello and published by Springer Science & Business Media. This book was released on 2010-01-22 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dietary Omega-3 Polyunsaturated Fatty Acids and Cancer provides all the latest information on the possible benefits of omega-3 polyunsaturated fatty acids (PUFAs) against a wide series of cancers. Several influential scientists in this field have contributed to make this book unique amongst the others published so far in this field. The chapters give detailed information about the results obtained in this field through experimental studies conducted on both animals and cultured cells, as well as through human intervention trials and epidemiological observational studies. This book represents an important tool for researchers working in nutrition and oncology, since it collects all the knowledge about omega-3 PUFAs and cancer, even the most recent, in a single publication. For the first time controversies among the different studies are also covered with great detail in this book. The book enables physicians to clearly understand on a scientific basis if their oncologic patients or patients at risk of cancer could actually benefit from a diet enriched in omega-3 PUFAs or from a dietary supplementation with these fatty acids. The book represents also a good resource for ordinary individuals as well as cancer patients to learn more about omega-3 PUFAs and understand how these dietary components may affect cancer growth.
Download or read book Value Added Ingredients and Enrichments of Beverages written by Alexandru Grumezescu and published by Academic Press. This book was released on 2019-06-22 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: Value-Added Ingredients and Enrichment of Beverages, Volume Fourteen in The Science of Beverages series, takes a multidisciplinary approach in addressing what consumers demand in natural beverages. This in-depth reference covers both natural and unnatural ingredients and explains their impact on consumer health and nutrition. Sweeteners, vitamins, oils and other natural ingredients to improve beverages are included. The book addresses some of the most common enrichments used in the industry, including those with biomedical and nutritional applications. This volume will be useful to anyone in the beverages industry who needs a better understanding of advances in the industry. - Discusses health-related benefits and risks, along with the potential harmful effects of additives and preservatives - Provides research examples of health promoting ingredients in beverages to further research and development - Presents key steps in designing formulations of enriched beverages, analysis, product development, shelf life, cost-benefit ratio and compliance with WHO regulations
Download or read book Pain in Osteoarthritis written by David T. Felson and published by John Wiley & Sons. This book was released on 2010-08-03 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: An authoritative investigation of the sources andtreatment of osteoarthritic joint pain Millions of people throughout the world suffer from osteoarthritis (OA)—a medical condition causing its sufferers excruciating pain that is often disabling. This is the first book to offer clinicians an in-depth understanding of the biological sources of osteoarthritic pain and how they can be treated. Here, a team of leading international authorities has contributed state-of-the-art information on: The Neuroscience of Articular Pain—spinal and peripheral mechanisms of joint pain; experimental models for the study of osteoarthritic pain; inflammatory mediators and nociception in arthritis; phantoms in rheumatology; and more Osteoarthritis and Pain—joint mechanisms and neuromuscular aspects of OA; bone pain and pressure in OA joints; structural correlates of OA pain; and more Treatment of Osteoarthritic Pain—general approaches to treatment; treatments targeting pain receptors; treatments targeting biomechanical abnormalities; and treatments targeting inflammation Whether you're a medical professional, researcher, student, or a generalist or specialist focusing on pain or arthritis, this is your one-stop reference for understanding and treating joint pain in osteoarthritis.
Download or read book Quality Control and Evaluation of Herbal Drugs written by Pulok K. Mukherjee and published by Elsevier. This book was released on 2019-05-30 with total page 788 pages. Available in PDF, EPUB and Kindle. Book excerpt: Quality Control and Evaluation of Herbal Drugs brings together current thinking and practices for evaluation of natural products and traditional medicines. The use of herbal medicine in therapeutics is on the rise in both developed and developing countries and this book facilitates the necessary development of quality standards for these medicines.This book elucidates on various challenges and opportunities for quality evaluation of herbal drugs with several integrated approaches including metabolomics, chemoprofiling, marker analysis, stability testing, good practices for manufacturing, clinical aspects, Ethnopharmacology and Ethnomedicine inspired drug development. Written by Prof. Pulok K Mukherjee, a leader in this field; the book highlights on various methods, techniques and approaches for evaluating the purity, quality, safety and efficacy of herbal drugs. Particular attention is paid to methods that assess these drugs' activity, the compounds responsible and their underlying mechanisms of action. The book describes the quality control parameters followed in India and other countries, including Japan, China, Bangladesh, and other Asian countries, as well as the regulatory profiles of the European Union and North America. This book will be useful in bio-prospecting of natural products and traditional medicine-inspired drug discovery and development. - Provides new information on the research and development of natural remedies - essential reading on the study and use of natural resources for preventative or healing purposes - Brings together current thinking and practices in quality control and standardization of herbal drugs highlighting several integrated approaches for metabolomics, chemo-profiling and marker analysis - Aids in developing knowledge of various techniques including macroscopy, microscopy, HPTLC, HPLC, LC-MS/MS, GC-MS etc. with the development of integrated methods for evaluation of botanicals used in traditional medicine - Assessment of herbal drugs through bio-analytical techniques, bioassay guided isolation, enzyme inhibition, pharmacological, microbiological, antiviral assays and safety related quality issues - References global organizations, such as the WHO, USFDA, CDSCO, AYUSH, TCM and others to serve as a comprehensive document for enforcement agencies, NGOs and regulatory authorities
Download or read book Clinical Case Studies for the Family Nurse Practitioner written by Leslie Neal-Boylan and published by John Wiley & Sons. This book was released on 2011-11-28 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical Case Studies for the Family Nurse Practitioner is a key resource for advanced practice nurses and graduate students seeking to test their skills in assessing, diagnosing, and managing cases in family and primary care. Composed of more than 70 cases ranging from common to unique, the book compiles years of experience from experts in the field. It is organized chronologically, presenting cases from neonatal to geriatric care in a standard approach built on the SOAP format. This includes differential diagnosis and a series of critical thinking questions ideal for self-assessment or classroom use.
Download or read book Exchange Lists for Meal Planning written by American Diabetes Association and published by . This book was released on 1995-01-01 with total page 32 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Dietary Supplements written by Melanie Johns Cupp and published by Springer Science & Business Media. This book was released on 2002-12-10 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: A treasure trove of uncommon and reliable scientific and clinical information for the toxicity and usefulness of today's leading nonherbal dietary supplements. The supplements detailed were chosen for their popularity, toxicity, and the quantity and quality of information available. Each monograph discusses the history of the compound; its chemical structure; its current and promoted uses, sources, and chemical composition; and its toxicity, pharmacokinetics, and physiological role. Also presented are case reports of adverse effects and interactions, as well as information on reproductive effects, chemical and biofluid analysis, and regulatory status. Each chapter is based on original studies published in reputable peer-reviewed journals, as well as on meta-analyses, systematic reviews, or other high-quality assessments by recognized experts.
Download or read book Dietary Supplements and Functional Foods written by Geoffrey P. Webb and published by Wiley-Blackwell. This book was released on 2006-02-20 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: The study of nutritional supplements has become increasingly important within orthodox establishments throughout the world, and as the market for these products continues to grow, so does the need for comprehensive scientifically sound information about these products, their properties and potential health effects. Geoffrey P. Webb, in this exciting and most useful new book, not only looks at the accepted uses of dietary supplements, such as the use of fish oils in the prevention of heart disease and arthritis, but also explores the wider picture, identifying common themes and principles or particular categories of supplements. Dietary Supplements and Functional Foods provides an excellent introductory text on this fascinating subject.
Download or read book Crohn s Disease and Ulcerative Colitis written by Daniel C. Baumgart and published by Springer. This book was released on 2017-03-01 with total page 671 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new edition is a unique combined resource for physicians and scientists addressing the needs of both groups. In addition to stimulating exchange and collaboration and shortening the path between discovery and application of new knowledge, the book helps clinicians understand new therapeutic concepts from their origins. The volume serves as a comprehensive guide to the current diagnostic modalities, including enhanced imaging techniques such as MRI and CT enterography, virtual colonoscopy, ultrasound, and endomicroscopy, as well as conventional and complex immunomodulatory principles. The latest edition also includes revised chapters from the previous edition, as well as new chapters reflecting current developments in the field. Written by experts in their field, Crohn’s Disease and Ulcerative Colitis: From Epidemiology and Immunobiology to a Rational Diagnostic and Therapeutic Approach, Second Edition is of great value to gastroenterologists, surgeons, internists, pediatricians and gynecologists trainees, as well as all those involved in Crohn’s disease, ulcerative colitis, and related autoimmune disorders.
Download or read book Frequently Prescribed Medications written by Michael Mancano and published by Jones & Bartlett Learning. This book was released on 2010-11-12 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: Health Sciences & Professions
Download or read book Stockley s Herbal Medicines Interactions written by Elizabeth M. Williamson and published by . This book was released on 2009 with total page 423 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains data on over 150 of the most commonly used herbal medicines, dietary supplements and nutraceuticals.
Download or read book Vitamins in Animal and Human Nutrition written by Lee Russell McDowell and published by John Wiley & Sons. This book was released on 2008-09-25 with total page 793 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vitamins in Animal and Human Nutrition contains concise, up-to-date information on vitamin nutrition for both animals and humans. The author defines these nutrients and describes their fascinating discovery, history and relationship to various diseases and deficiencies. Discussion of vitamins also includes their chemical structure, properties and antagonists; analytical procedures; metabolism; functions; requirements; sources; supplementation and toxicity. Vitamin-like substances, essential fatty acids and vitamin supplementation considerations are also examined. This book will be useful worldwide as a textbook and as an authoritative reference for research and extension specialists, feed manufacturers, teachers, students and others. It provides a well-balanced approach to both animal and clinical human nutrition and compares chemical, metabolic and functional aspects of vitamins and their practical and applied considerations. A unique feature of the book is its description of the implications of vitamin deficiencies and excesses and the conditions that might occur in human and various animal species.
Download or read book Evidence Based Approach to Vitamins and Minerals written by Jane Higdon and published by Thieme. This book was released on 2011-09-07 with total page 547 pages. Available in PDF, EPUB and Kindle. Book excerpt: The latest and most accurate, peer-reviewed information on the role of vitamins and minerals in health and disease An Evidence-Based Approach to Vitamins and Minerals: Health Benefits and Intake Recommendations is a trusted resource for the health professional who needs to interpret the explosion of studies on the role of micronutrients in health and disease and who is concerned about the proliferation of dietary supplements now available to the consumer. This evidence-based reference, now in a second edition, presents the most current scientific, epidemiological and clinical research on the role of vitamins and minerals in preventing disease and promoting optimal health. Organized by micronutrient, the book covers biological function, deficiency, recommended daily allowance, role in disease prevention and treatment, sources, safety, and interactions with other micronutrients and drugs--all endorsed by the internationally acclaimed Linus Pauling Institute at Oregon State University. Special Features: Each chapter reviewed by a recognized expert in the field, who also served on the book's Editorial Advisory Board Contains the latest intake recommendations from the Linus Pauling Institute, as well as the Food and Nutrition Board of the Institute for Medicine Provides a complete index by disease or disorder that facilitates easy location of condition-specific information found in multiple chapters Extensively referenced, with hundreds of citations from the most current experimental, clinical and epidemiological studies Includes useful appendices covering drug-nutrient interactions and nutrient-nutrient interactions, a glossary of terms, a units conversion table, and the Linus Pauling Institute "Prescription for Health," summarizing its recommendations for a healthy diet, lifestyle, and supplement use Taking the approach that micronutrients play a significant role not only in preventing deficiency disease, but in enhancing general health and averting chronic disease, this book is essential for physicians, nutritionists, and allied health professionals who need the most reliable, up-to-date information in this rapidly expanding field.
Download or read book Functional Foods and Nutraceuticals written by Rotimi E. Aluko and published by Springer Science & Business Media. This book was released on 2012-06-05 with total page 163 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Functional food or medicinal food is any fresh or processed food claimed to have a health-promoting and/or disease-preventing property beyond the basic nutritional function of supplying nutrients, although there is no consensus on an exact definition of the term. This is an emerging field in food science, in which such foods are usually accompanied by health claims for marketing purposes, such as a company's ‘cereal is a significant source of fiber. Studies have shown that an increased amount of fiber in one's diet can decrease the risk of certain types of cancer in individuals.’ Functional foods are sometimes called nutraceuticals, a portmanteau of nutrition and pharmaceutical, and can include food that has been genetically modified. The general category includes processed food made from functional food ingredients, or fortified with health-promoting additives, like "vitamin-enriched" products, and also fresh foods (e.g., vegetables) that have specific claims attached. Fermented foods with live cultures are often also considered to be functional foods with probiotic benefits."
Download or read book Innovations in Food Technology written by Pragya Mishra and published by Springer Nature. This book was released on 2020-10-12 with total page 522 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book gathers a collection of essays that describe recent innovations in food technology including food processing, packaging, food safety, and novel ingredients. By 2050, the world will face the challenge of having to feed an estimated 9 billion people. In order to meet that challenge, innovations in food research are of the utmost importance. The book is divided into four sections, each of which explores an important aspect like food processing, food microbiology, and nutritional security. Written by respected scholars in the field, the respective chapters discuss a range of new and enhanced food materials, as well as processing innovations to extend shelf life and reduce toxic effects. The book also addresses the health potential of various nutraceuticals, bio-absorption of metals and their positive impacts on living systems, as well as methods for reducing food wastage, preventing the loss of nutritive value, and preserving or enhancing palatability. Given its scope, the book will be highly interesting for food scientists, both in academia and the food industry. It will also benefit advanced graduate students and senior researchers.
