Download or read book Untangling Alzheimer s written by Tam Cummings and published by . This book was released on 2013-04 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: A gerontologist explains dementia and Alzheimer's disease, from diagnosis to death in terms family and professional caregivers can understand. The stages of dementia, the history of Alzheimer's and the physiology of the disease are explained. Communication techniques, working with and tracking combative behaviors for the doctor are discussed, as well as techniques to address caregiver stress. Activities for person's with dementia are offered. The progression of the disease with an emphasis on the A's of Alzheimer's are provided, giving caregivers a clear explanation of falls, loss of speech, movement and memory. Vignettes from case histories are used to illustrate key points in the book. A detailed and compassionate explanation of the end of life is presented for caregivers.
Download or read book Untangling Dementia written by Tam Cummings and published by . This book was released on 2012-04-01 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book American Dementia written by Daniel R. George and published by JHU Press. This book was released on 2021-09-14 with total page 425 pages. Available in PDF, EPUB and Kindle. Book excerpt: Have the social safety nets, environmental protections, and policies to redress wealth and income inequality enacted after World War II contributed to declining rates of dementia today—and how do we improve brain health in the future? Winner of the American Book Fest Health: Aging/50+ by the American Book Fest, Living Now Book Award: Mature Living/Aging by the Living Now Book Awards For decades, researchers have chased a pharmaceutical cure for memory loss. But despite the fact that no disease-modifying biotech treatments have emerged, new research suggests that dementia rates have actually declined in the United States and Western Europe over the last decade. Why is this happening? And what does it mean for brain health in the future? In American Dementia, Daniel R. George, PhD, MSc, and Peter J. Whitehouse, MD, PhD, argue that the current decline of dementia may be strongly linked to mid–twentieth century policies that reduced inequality, provided widespread access to education and healthcare, and brought about cleaner air, soil, and water. They also • explain why Alzheimer's disease, an obscure clinical label until the 1970s, is the hallmark illness of our current hyper-capitalist era; • reveal how the soaring inequalities of the twenty-first century—which are sowing poverty, barriers to healthcare and education, loneliness, lack of sleep, stressful life events, environmental exposures, and climate change—are reversing the gains of the twentieth century and damaging our brains; • tackle the ageist tendencies in our culture, which disadvantage both vulnerable youth and elders; • make an evidence-based argument that policies like single-payer healthcare, a living wage, and universal access to free higher education and technical training programs will build collective resilience to dementia; • promote strategies that show how local communities can rise above the disconnection and loneliness that define our present moment and come together to care for our struggling neighbors. Ultimately, American Dementia asserts that actively remembering lessons from the twentieth century which help us become a healthier, wiser, and more compassionate society represents our most powerful intervention for preventing Alzheimer's and protecting human dignity. Exposing the inconvenient truths that confound market-based approaches to memory enhancement as well as broader social organization, the book imagines how we can act as citizens to protect our brains, build the cognitive resilience of younger generations, and rise to the moral challenge of caring for the cognitively frail.
Download or read book A Guide to Understanding Alzheimer s and Other Dementias written by Tam Cummings and published by . This book was released on 2009-06-04 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: A guide to the history of dementia and Alzheimer's including a person's perception of his/her environment, disease stages, communication changes, physiological alterations, grief and death.
Download or read book Finding the Right Words written by Cindy Weinstein and published by JHU Press. This book was released on 2021-09-07 with total page 209 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This memoir tells the story of a man's deterioration from Alzheimer disease from two perspectives. His daughter, an English professor at Caltech, describes her father's dementia, using her expertise in language and literature as a way to frame his loss of words, spatial orientation, identity, behavioral decorum, and memory. The physician, an academic neurologist at the University of California at San Francisco, explains the science behind Alzheimer disease using his expertise in neurology, articulating to a general audience how dementia assaults the brain"--
Download or read book From the Corner Office to Alzheimer s written by Michael Ellenbogen and published by Createspace Independent Publishing Platform. This book was released on 2014-07-31 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Imagine having a mysterious illness take over your mind. Over the next 10 years, you try to navigate a health care and social system that is not equipped to address what is happening to you. As you slowly lose your ability to think and remember, you have to try to hide the losses to protect you and your family financially. You encounter doctors who are at best baffled, and order a series of nonspecific, redundant, and uninformative studies. If you want to know what it is like to walk in the shoes of one person with Alzheimer's, read this book, whether you are a patient, care partner, doctor, or other health provider. It is raw and scary, as well as inspiring, given the self-disclosure. As well as describing, sometimes painfully and in harrowing detail, what we are doing wrong, it can tell us a great deal about what we need to do differently going forward.. Every individual with an illness like Alzheimer's deserves a prompt, thorough, empathic, and well-informed evaluation. Every family needs and deserves support. Every reasonable research question should be pursued. At the close of his book, Michael Ellenbogen says that, "I would like to be remembered for influencing change...and helping others." I think that he will be. Pierre N. Tariot, MD Director, Banner Alzheimer's Institute Research Professor of Psychiatry University of Arizona College of Medicine Phoenix, Arizona
Download or read book Surviving Alzheimer s written by PAULA SPENCER. SCOTT and published by . This book was released on 2018-01-11 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book recommended by dementia experts and family caregivers as the most complete, practical guide to Alzheimer's and other dementias-now updated and expanded through end-of-life care. This new edition of Surviving Alzheimer's offers the best, most current thinking on how to help a loved one with memory loss and related symptoms without sacrificing YOU. You'll learn: What's behind odd, frustrating behaviors like repetition, wandering, personality changes, bathing resistance, and aggression-and what you can do How to defuse resentment, guilt, and family friction What to say for better communication and more cooperation Special advice for spouses, out-of-town caregivers, and other specific situations 100s of confidence-raising solutions from top doctors, social workers, dementia specialists, and family caregivers All in a fast, scannable format perfect for busy or overwhelmed dementia helpers.
Download or read book Tau oligomers written by Jesus Avila and published by Frontiers E-books. This book was released on 2014-08-18 with total page 114 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurofibrillary tangles (NFTs) composed of intracellular aggregates of tau protein are a key neuropathological feature of Alzheimer’s Disease (AD) and other neurodegenerative diseases, collectively termed tauopathies. The abundance of NFTs has been reported to correlate positively with the severity of cognitive impairment in AD. However, accumulating evidences derived from studies of experimental models have identified that NFTs themselves may not be neurotoxic. Now, many of tau researchers are seeking a “toxic” form of tau protein. Moreover, it was suggested that a “toxic” tau was capable to seed aggregation of native tau protein and to propagate in a prion-like manner. However, the exact neurotoxic tau species remain unclear. Because mature tangles seem to be non-toxic component, “tau oligomers” as the candidate of “toxic” tau have been investigated for more than one decade. In this topic, we will discuss our consensus of “tau oligomers” because the term of “tau oligomers” [e.g. dimer (disulfide bond-dependent or independent), multimer (more than dimer), granular (definition by EM or AFM) and maybe small filamentous aggregates] has been used by each researchers definition. From a biochemical point of view, tau protein has several unique characteristics such as natively unfolded conformation, thermo-stability, acid-stability, and capability of post-translational modifications. Although tau protein research has been continued for a long time, we are still missing the mechanisms of NFT formation. It is unclear how the conversion is occurred from natively unfolded protein to abnormally mis-folded protein. It remains unknown how tau protein can be formed filaments [e.g. paired helical filament (PHF), straight filament and twisted filament] in cells albeit in vitro studies confirmed tau self-assembly by several inducing factors. Researchers are still debating whether tau oligomerization is primary event rather than tau phosphorylation in the tau pathogenesis. Inhibition of either tau phosphorylation or aggregation has been investigated for the prevention of tauopathies, however, it will make an irrelevant result if we don’t know an exact target of neurotoxicity. It is a time to have a consensus of definition, terminology and methodology for the identification of “tau oligomers”.
Download or read book Alzheimer s Disease written by Anne Brown Rodgers and published by . This book was released on 2008 with total page 80 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Ageing and Dementia written by Kurt Jellinger and published by Springer Science & Business Media. This book was released on 2002-08-20 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epidemiological studies, modern clinical, neuroimaging, neuropsychological, molecular biological, and genetic studies have considerably enhanced our knowledge about ageing processes of the human brain, its sequelae, diagnostic, and therapeutic possibilities and limits. In addition to Alzheimer's disease and other degenerative dementias, the impact of cerebrovascular lesions and their risk factors in the pathogenesis of cognitive disorders of the aged are increasingly acknowledged, and the recognition of mild cognitive impairment as a frequent initial stage of developing dementia is becoming an increasingly important diagnostic and therapeutic problem. The included papers were presented at the 7th International Symposium in Graz, Sept. 2001 and give a timely overview of the current and future concepts of pathogenesis, diagnosis, and treatment strategies of pathological brain ageing and dementias, early recognition of mild cognitive impairment and future possiblities of prevention of dementing processes.
Download or read book Dementia from the Inside written by Jennifer Bute and published by SPCK. This book was released on 2018-11-15 with total page 131 pages. Available in PDF, EPUB and Kindle. Book excerpt: ‘Many assume that living with dementia is one long term steady decline. Jennifer’s insightful book debunks that myth.’ – Jeremy Hughes, Chief Executive, Alzheimer's Society Jennifer Bute was a highly qualified senior doctor in a large clinical practice, whose patients included those with dementia. Then she began to notice symptoms in herself. She was finally given a diagnosis of Young Onset Dementia in 2009. After resigning as a GP, she resolved to explore what could be done to slow the progress of dementia. The aim of this practical book is to help people who are living with dementia and to give hope to those who are with them on the dementia journey. Jennifer believes that her dementia is an opportunity as well as a challenge. Her important insights are that the person ‘inside’ remains and can be reached, even when masked by the condition, and that spirituality rises as cognition becomes limited. ‘The observant physician shines through in Dr Bute's book, while her practical advice reveals the resourcefulness of an inventor. Alzheimer’s disease has surely met one of its toughest ever adversaries!’ – Peter Garrard, Professor of Neurology, University of London
Download or read book Insights into Human Neurodegeneration Lessons Learnt from Drosophila written by Mousumi Mutsuddi and published by Springer Nature. This book was released on 2019-12-05 with total page 470 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is aimed at generating an updated reservoir of scientific endeavors undertaken to unravel the complicated yet intriguing topic of neurodegeneration. Scientists from Europe, USA and India who are experts in the field of neurodegenerative diseases have contributed to this book. This book will help readers gain insight into the recent knowledge obtained from Drosophila model, in understanding the molecular mechanisms underlying neurodegenerative disorders and also unravel novel scopes for therapeutic interventions. Different methodologies available to create humanized fly models that faithfully reflects the pathogenicities associated with particular disorders have been described here. It also includes information on the exciting area of neural stem cells. A brief discussion on neurofibrillary tangles, precedes the elaborate description of lessons learnt from Drosophila about Alzheimer's, Parkinson’s, Spinomuscular Atrophy, Huntington’s diseases, RNA expansion disorders and Hereditary Spastic Paraplegia. We have concluded the book with the use of Drosophila for identifying pharmacological therapies for neurodegenerative disorders. The wide range of topics covered here will not only be relevant for beginners who are new to the concept of the extensive utility of Drosophila as a model to study human disorders; but will also be an important contribution to the scientific community, with an insight into the paradigm shift in our understanding of neurodegenerative disorders. Completed with informative tables and communicative illustrations this book will keep the readers glued and intrigued. We have comprehensively anthologized the lessons learnt on neurodegeneration from Drosophila and have thus provided an insight into the multidimensional aspects of pathogenicities of majority of the neurodegenerative disorders.
Download or read book Insights in alzheimer s disease and related dementias written by Agustin Ibanez and published by Frontiers Media SA. This book was released on 2022-12-29 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Elizabeth Is Missing written by Emma Healey and published by Harper Collins. This book was released on 2014-06-10 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: HOW DO YOU SOLVE A MYSTERY WHEN YOU CAN'T REMEMBER THE CLUES? In this darkly riveting debut novel—a sophisticated psychological mystery that is also an heartbreakingly honest meditation on memory, identity, and aging—an elderly woman descending into dementia embarks on a desperate quest to find the best friend she believes has disappeared, and her search for the truth will go back decades and have shattering consequences. Maud, an aging grandmother, is slowly losing her memory—and her grip on everyday life. Yet she refuses to forget her best friend Elizabeth, whom she is convinced is missing and in terrible danger. But no one will listen to Maud—not her frustrated daughter, Helen, not her caretakers, not the police, and especially not Elizabeth’s mercurial son, Peter. Armed with handwritten notes she leaves for herself and an overwhelming feeling that Elizabeth needs her help, Maud resolves to discover the truth and save her beloved friend. This singular obsession forms a cornerstone of Maud’s rapidly dissolving present. But the clues she discovers seem only to lead her deeper into her past, to another unsolved disappearance: her sister, Sukey, who vanished shortly after World War II. As vivid memories of a tragedy that occurred more fifty years ago come flooding back, Maud discovers new momentum in her search for her friend. Could the mystery of Sukey’s disappearance hold the key to finding Elizabeth?
Download or read book Is Aging a Disease written by Michael Allan Singer and published by . This book was released on 2019 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Each species has its own characteristic aging trajectory coded by a species-specific developmental program. This developmental program is triggered at the time of fertilization, hence aging begins at conception. Within a species there are considerable variations in the aging phenotype between individuals due to the plasticity of the developmental process and its inherent stochasticity. The evolution of a species is due to genetic changes in its underlying developmental program and when enough genetic changes have accumulated a new species emerges with its own characteristic aging phenotype. Therefore, speciation and aging are linked processes. Over the evolutionary course of the human lineage, culture has been an important driver of evolutionary change. Culture is not restricted to the human lineage but only humans have evolved cumulative culture; the transmission of modified cultural practices across generations. Early cultural innovations such as toolmaking, agriculture and dairy farming had a utilitarian function. However, over the past 100 to 150 years, there has been a significant change in the pace and nature of cultural innovations. Although many cultural innovations still have a utilitarian function, a new category of cultural innovations has emerged that have "entertainment" functions in the domains of social communication and information transfer. In addition, cultural practices by the tobacco, food and technological industries have been used to modify population behaviors, physiology and beliefs. Over the past 50 to 75 years, there has emerged so called chronic non-infectious diseases, which occurrence parallels the development of these new cultural innovations and practices. In addition, culture has now become the primary driver of human evolution. In answer to the question posed by the title of this book, aging is not a disease and diseases are cultural constructs used to define variants in the aging process.
Download or read book Unraveling Faculty Burnout written by Rebecca Pope-Ruark and published by JHU Press. This book was released on 2022-09-20 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: A timely book about assessing, coping with, and mitigating burnout in higher education. Faculty often talk about how busy, overwhelmed, and stressed they are. These qualities are seen as badges of honor in a capitalist culture that values productivity above all else. But for many women in higher education, exhaustion and stress go far deeper than end-of-the-semester malaise. Burnout, a mental health syndrome caused by chronic workplace stress, is endemic to higher education in a patriarchal, productivity-obsessed culture. In this unique book for women in higher education, Rebecca Pope-Ruark, PhD, draws from her own burnout experience, as well as collected stories of faculty in various roles and career stages, interviews with coaches and educational developers, and extensive secondary research to address and mitigate burnout. Pope-Ruark lays out four pillars of burnout resilience for faculty members: purpose, compassion, connection, and balance. Each chapter contains relatable stories, reflective opportunities and exercises, and advice from women in higher education. Blending memoir, key research, and reflection opportunities, Pope-Ruark helps faculty not only address burnout personally but also use the tools in this book to eradicate the systemic conditions that cause it in the first place. As burnout becomes more visible, we can destigmatize it by acknowledging that women are not unraveling; instead, women in higher education are reckoning with the productivity cult embedded in our institutions, recognizing how it shapes their understanding and approach to faculty work, and learning how they can remedy it for themselves, their peers, and women faculty in the future. Contributors: Lee Skallerup Bessette, Cynthia Ganote, Emily O. Gravett, Hillary Hutchinson, Tiffany D. Johnson, Bridget Lepore, Jennifer Marlow, Sharon Michler, Marie Moeller, Valerie Murrenus Pilmaier, Catherine Ross, Kristi Rudenga, Katherine Segal, Kryss Shane, Jennifer Snodgrass, Lindsay Steiner, Kristi Verbeke
Download or read book Genes Environment and Alzheimer s Disease written by Orly Lazarov and published by Academic Press. This book was released on 2016-02-25 with total page 449 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genes, Environment and Alzheimer's Disease discusses the role that activities such as exercise can play in cardiovascular health, while also highlighting the fact that the last 10 years have brought great discoveries in the strong environmental component of brain disorders, neurodegeneration, and cognitive decline. It is now clear that brain insult is an environmental risk factor for AD, while on the other hand, lifestyle components such as exercise and level of education may play a protective role, delaying the onset and/or severity of the disease. Evidence from experiments in rodent models of Alzheimer's disease contributes major insight into the molecular mechanisms by which the environment plays its role in AD. Additionally, there are diseases related to lifestyle that may lead to AD. This volume reviews new discoveries related to all these factors, serving as a translational tool for clinicians and researchers interested in genetic and environmental risk factors for the disease. - Provides the first volume to link genetic and environmental risk factors for Alzheimer's disease and dementia - Aids researchers and clinicians in understanding the basic mechanisms of Alzheimer's disease and cognitive decline - Brings the basic science and clinical perspectives together in a single volume, facilitating translational possibilities - Includes a range of molecular to behavioral components assembled into a single volume that creates an excellent resource for basic and clinical neuroscientists
