Download or read book Ultrasound and Photoacoustic Imaging to Assess Microvasculature in Tissue Engineered Constructs written by Seung Yun Nam and published by . This book was released on 2009 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Assessment of neovascular growth is essential in various applications related to tissue engineering. However, the process of vascularization from progenitor cells contributing vascular growth is not well understood. Hence, an imaging modality, which is easily applicable, reliable, and capable of quantitative assessment of vascular growth or regression in a three-dimensional environment, is required. In this study, the combined ultrasound and photoacoustic imaging method was applied to assess microvasculature in tissue engineered constructs. Hydrogels that spontaneously promote tube formation from implanted mesenchymal stem cells (MSCs) were imaged. PEGylated fibrin gels, supporting the development of capillary growth were implanted in a Lewis rat. After one week, the rat was euthanized and the gel implants were excised and positioned in water cuvettes for imaging. Ultrasound and photoacoustic images were acquired with single element 25 MHz and 48 MHz focused ultrasound transducers interfaced with a nanosecond pulsed laser source operating at 532 nm wavelength. The 3D ultrasound and photoacoustic image was reconstructed based on hundreds of 2D ultrasound images obtained by mechanically scanning the transducer. The ultrasound and photoacoustic images had good agreement with the vascular structure in the gel samples indicating that the combined ultrasound and photoacoustic imaging is capable of assessing growth of micro blood vessels.
Download or read book LED Based Photoacoustic Imaging written by Mithun Kuniyil Ajith Singh and published by Springer Nature. This book was released on 2020-04-07 with total page 393 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book highlights the use of LEDs in biomedical photoacoustic imaging. In chapters written by key opinion leaders in the field, it covers a broad range of topics, including fundamentals, principles, instrumentation, image reconstruction and data/image processing methods, preclinical and clinical applications of LED-based photoacoustic imaging. Apart from preclinical imaging studies and early clinical pilot studies using LED-based photoacoustics, the book includes a chapter exploring the opportunities and challenges of clinical translation from an industry perspective. Given its scope, the book will appeal to scientists and engineers in academia and industry, as well as medical experts interested in the clinical applications of photoacoustic imaging.
Download or read book Artificial Intelligence in Medical Imaging written by Erik R. Ranschaert and published by Springer. This book was released on 2019-01-29 with total page 373 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a thorough overview of the ongoing evolution in the application of artificial intelligence (AI) within healthcare and radiology, enabling readers to gain a deeper insight into the technological background of AI and the impacts of new and emerging technologies on medical imaging. After an introduction on game changers in radiology, such as deep learning technology, the technological evolution of AI in computing science and medical image computing is described, with explanation of basic principles and the types and subtypes of AI. Subsequent sections address the use of imaging biomarkers, the development and validation of AI applications, and various aspects and issues relating to the growing role of big data in radiology. Diverse real-life clinical applications of AI are then outlined for different body parts, demonstrating their ability to add value to daily radiology practices. The concluding section focuses on the impact of AI on radiology and the implications for radiologists, for example with respect to training. Written by radiologists and IT professionals, the book will be of high value for radiologists, medical/clinical physicists, IT specialists, and imaging informatics professionals.
Download or read book Molecular Imaging written by Brian D. Ross and published by Academic Press. This book was released on 2021-08-03 with total page 1872 pages. Available in PDF, EPUB and Kindle. Book excerpt: The detection and measurement of the dynamic regulation and interactions of cells and proteins within the living cell are critical to the understanding of cellular biology and pathophysiology. The multidisciplinary field of molecular imaging of living subjects continues to expand with dramatic advances in chemistry, molecular biology, therapeutics, engineering, medical physics and biomedical applications. Molecular Imaging: Principles and Practice, Volumes 1 and 2, Second Edition provides the first point of entry for physicians, scientists, and practitioners. This authoritative reference book provides a comprehensible overview along with in-depth presentation of molecular imaging concepts, technologies and applications making it the foremost source for both established and new investigators, collaborators, students and anyone interested in this exciting and important field. The most authoritative and comprehensive resource available in the molecular-imaging field, written by over 170 of the leading scientists from around the world who have evaluated and summarized the most important methods, principles, technologies and data Concepts illustrated with over 600 color figures and molecular-imaging examples Chapters/topics include, artificial intelligence and machine learning, use of online social media, virtual and augmented reality, optogenetics, FDA regulatory process of imaging agents and devices, emerging instrumentation, MR elastography, MR fingerprinting, operational radiation safety, multiscale imaging and uses in drug development This edition is packed with innovative science, including theranostics, light sheet fluorescence microscopy, (LSFM), mass spectrometry imaging, combining in vitro and in vivo diagnostics, Raman imaging, along with molecular and functional imaging applications Valuable applications of molecular imaging in pediatrics, oncology, autoimmune, cardiovascular and CNS diseases are also presented This resource helps integrate diverse multidisciplinary concepts associated with molecular imaging to provide readers with an improved understanding of current and future applications
Download or read book Small Animal Imaging written by Fabian Kiessling and published by Springer. This book was released on 2017-05-22 with total page 871 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook is a practical guide to the use of small animal imaging in preclinical research that will assist in the choice of imaging modality and contrast agent and in study design, experimental setup, and data evaluation. All established imaging modalities are discussed in detail, with the assistance of numerous informative illustrations. While the focus of the new edition remains on practical basics, it has been updated to encompass a variety of emerging imaging modalities, methods, and applications. Additional useful hints are also supplied on the installation of a small animal unit, study planning, animal handling, and cost-effective performance of small animal imaging. Cross-calibration methods and data postprocessing are considered in depth. This new edition of Small Animal Imaging will be an invaluable aid for researchers, students, and technicians involved in research into and applications of small animal imaging.
Download or read book Imaging in Dermatology written by Michael R. Hamblin and published by Academic Press. This book was released on 2016-07-29 with total page 562 pages. Available in PDF, EPUB and Kindle. Book excerpt: Imaging in Dermatology covers a large number of topics in dermatological imaging, the use of lasers in dermatology studies, and the implications of using these technologies in research. Written by the experts working in these exciting fields, the book explicitly addresses not only current applications of nanotechnology, but also discusses future trends of these ever-growing and rapidly changing fields, providing clinicians and researchers with a clear understanding of the advantages and challenges of laser and imaging technologies in skin medicine today, along with the cellular and molecular effects of these technologies. Outlines the fundamentals of imaging and lasers for dermatology in clinical and research settings Provides knowledge of current and future applications of dermatological imaging and lasers Coherently structured book written by the experts working in the fields covered
Download or read book Lab on Fiber Technology written by Andrea Cusano and published by Springer. This book was released on 2014-07-29 with total page 377 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on a research field that is rapidly emerging as one of the most promising ones for the global optics and photonics community: the “lab-on-fiber” technology. Inspired by the well-established "lab on-a-chip" concept, this new technology essentially envisages novel and highly functionalized devices completely integrated into a single optical fiber for both communication and sensing applications. Based on the R&D experience of some of the world's leading authorities in the fields of optics, photonics, nanotechnology, and material science, this book provides a broad and accurate description of the main developments and achievements in the lab-on-fiber technology roadmap, also highlighting the new perspectives and challenges to be faced. This book is essential for scientists interested in the cutting-edge fiber optic technology, but also for graduate students.
Download or read book Biomedical Photoacoustic Imaging written by Paul Beard and published by Wiley. This book was released on 2015-08-03 with total page 600 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the theory, implementation, and biomedical applications of photoacoustic imaging. It describes photoacoustic signal generation and image reconstruction theory in depth, as well as many potential applications in oncology, neurology, and cardiology in both clinical diagnosis and basic research. This text offers material useful to supplement existing reading lists for courses on medical ultrasound imaging and medical imaging in general, as well as courses used to train radiographers and clinical radiologists.
Download or read book Materials for Biomedical Engineering Hydrogels and Polymer based Scaffolds written by Alina-Maria Holban and published by Elsevier. This book was released on 2019-03-20 with total page 562 pages. Available in PDF, EPUB and Kindle. Book excerpt: Materials for Biomedical Engineering: Hydrogels and Polymer-Based Scaffolds discusses the use of a wide variety of hydrogels as bioactive scaffolds in regenerative medicine, including updates on innovative materials and their properties. Various types of currently investigated scaffolding materials and hydrogels are discussed, as is their future roles and applications, the main techniques for scaffold fabrication, and their characterization procedures. Readers will be able to use this book as a guide for the selection of the best materials for a specific application. Provides a valuable resource of recent scientific progress, highlighting the most well-known applications of hydrogels as bioactive scaffolds in regenerative medicine Includes novel opportunities and ideas for developing or improving technologies in biomaterials, and in related biomedical industries Features at least 50% of references from the last 2-3 years
Download or read book Nanotechnology Characterization Tools for Tissue Engineering and Medical Therapy written by Challa S.S.R. Kumar and published by Springer Nature. This book was released on 2019-11-22 with total page 467 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ninth volume of a 40 volume series on nanoscience and nanotechnology, edited by the renowned scientist Challa S.S.R. Kumar. This handbook gives a comprehensive overview about Nanotechnology Characterization Tools for Tissue Engineering and Medical Therapy. Modern applications and state-of-the-art techniques are covered and make this volume an essential reading for research scientists in academia and industry.
Download or read book Biophotonics for Medical Applications written by Igor Meglinski and published by Elsevier. This book was released on 2015-06-29 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biophotonics for Medical Applications presents information on the interface between laser optics and cell biology/medicine. The book discusses the development and application of photonic techniques that aid the diagnosis and therapeutics of biological tissues in both healthy and diseased states. Chapters cover the fundamental technologies used in biophotonics and a wide range of therapeutic and diagnostic applications. Presents information on the interface between laser optics and cell biology/medicine Discusses the development and application of photonic techniques which aid the diagnosis and therapeutics of biological tissues in both healthy and diseased states Presents the fundamental technologies used in biophotonics and a wide range of therapeutic and diagnostic applications
Download or read book Diagnostic Ultrasound Imaging Inside Out written by Thomas L. Szabo and published by Academic Press. This book was released on 2013-12-05 with total page 829 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diagnostic Ultrasound Imaging provides a unified description of the physical principles of ultrasound imaging, signal processing, systems and measurements. This comprehensive reference is a core resource for both graduate students and engineers in medical ultrasound research and design. With continuing rapid technological development of ultrasound in medical diagnosis, it is a critical subject for biomedical engineers, clinical and healthcare engineers and practitioners, medical physicists, and related professionals in the fields of signal and image processing. The book contains 17 new and updated chapters covering the fundamentals and latest advances in the area, and includes four appendices, 450 figures (60 available in color on the companion website), and almost 1,500 references. In addition to the continual influx of readers entering the field of ultrasound worldwide who need the broad grounding in the core technologies of ultrasound, this book provides those already working in these areas with clear and comprehensive expositions of these key new topics as well as introductions to state-of-the-art innovations in this field. Enables practicing engineers, students and clinical professionals to understand the essential physics and signal processing techniques behind modern imaging systems as well as introducing the latest developments that will shape medical ultrasound in the future Suitable for both newcomers and experienced readers, the practical, progressively organized applied approach is supported by hands-on MATLAB® code and worked examples that enable readers to understand the principles underlying diagnostic and therapeutic ultrasound Covers the new important developments in the use of medical ultrasound: elastography and high-intensity therapeutic ultrasound. Many new developments are comprehensively reviewed and explained, including aberration correction, acoustic measurements, acoustic radiation force imaging, alternate imaging architectures, bioeffects: diagnostic to therapeutic, Fourier transform imaging, multimode imaging, plane wave compounding, research platforms, synthetic aperture, vector Doppler, transient shear wave elastography, ultrafast imaging and Doppler, functional ultrasound and viscoelastic models
Download or read book Angiogenesis Assays written by Carolyn A. Staton and published by John Wiley & Sons. This book was released on 2007-01-11 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: Angiogenesis, the development of new blood vessels from the existing vasculature, is essential for physiological growth and over 18,000 research articles have been published describing the role of angiogenesis in over 70 different diseases, including cancer, diabetic retinopathy, rheumatoid arthritis and psoriasis. One of the most important technical challenges in such studies has been finding suitable methods for assessing the effects of regulators of eh angiogenic response. While increasing numbers of angiogenesis assays are being described both in vitro and in vivo, it is often still necessary to use a combination of assays to identify the cellular and molecular events in angiogenesis and the full range of effects of a given test protein. Although the endothelial cell - its migration, proliferation, differentiation and structural rearrangement - is central to the angiogenic process, it is not the only cell type involved. the supporting cells, the extracellular matrix and the circulating blood with its cellular and humoral components also contribute. In this book, experts in the use of a diverse range of assays outline key components of these and give a critical appraisal of their strengths and weaknesses. Examples include assays for the proliferation, migration and differentiation of endothelial cells in vitro, vessel outgrowth from organ cultures, assessment of endothelial and mural cell interactions, and such in vivo assays as the chick chorioallantoic membrane, zebrafish, corneal, chamber and tumour angiogenesis models. These are followed by a critical analysis of the biological end-points currently being used in clinical trials to assess the clinical efficacy of anti-angiogenic drugs, which leads into a discussion of the direction future studies should take. This valuable book is of interest to research scientists currently working on angiogenesis in both the academic community and in the biotechnology and pharmaceutical industries. Relevant disciplines include cell and molecular biology, oncology, cardiovascular research, biotechnology, pharmacology, pathology and physiology.
Download or read book Textbook of Stroke Medicine written by Michael Brainin and published by Cambridge University Press. This book was released on 2014-09-11 with total page 425 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fully revised throughout, the new edition of this concise textbook is aimed at doctors preparing to specialize in stroke care.
Download or read book Micro computed Tomography micro CT in Medicine and Engineering written by Kaan Orhan and published by Springer. This book was released on 2019-07-25 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on applications of micro CT, CBCT and CT in medicine and engineering, comprehensively explaining the basic principles of these techniques in detail, and describing their increasing use in the imaging field. It particularly highlights the scanning procedure, which represents the most crucial step in micro CT, and discusses in detail the reconstruction process and the artifacts related to the scanning processes, as well as the imaging software used in analysis. Written by international experts, the book illustrates the application of micro CT in different areas, such as dentistry, medicine, tissue engineering, aerospace engineering, geology, material engineering, civil engineering and additive manufacturing. Covering different areas of application, the book is of interest not only to specialists in the respective fields, but also to broader audience of professionals working in the fields of imaging and analysis, as well as to students of the different disciplines.
Download or read book Biomechanics of Tendons and Ligaments written by Johanna Buschmann and published by Woodhead Publishing. This book was released on 2017-05-10 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomechanics of Tendons and Ligaments: Tissue Reconstruction looks at the structure and function of tendons and ligaments. Biological and synthetic biomaterials for their reconstruction and regeneration are reviewed, and their biomechanical performance is discussed. Regeneration tendons and ligaments are soft connective tissues which are essential for the biomechanical function of the skeletal system. These tissues are often prone to injuries which can range from repetition and overuse, to tears and ruptures. Understanding the biomechanical properties of ligaments and tendons is essential for their repair and regeneration. Contains systematic coverage on how both healthy and injured tendons and ligaments work Includes coverage of repair and regeneration strategies for tendons and ligaments Presents an Interdisciplinary analysis on the topic
Download or read book Photoacoustic Tomography written by Minghua Xu and published by CRC PressI Llc. This book was released on 2014-09-30 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt:
