Download or read book Turmeric and Curcumin for Neurodegenerative Diseases written by Magisetty Obulesu and published by Academic Press. This book was released on 2021-01-26 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: Turmeric and Curcumin for Neurodegenerative Diseases examines protective mechanisms of turmeric products and novel nanotechnological therapeutics and biomaterial design strategies to circumvent Alzheimer’s Disease, Parkinson’s, and liver diseases. With neurodegenerative and liver diseases posing a serious threat to health care systems worldwide, this book addresses how existing nanotechnology and therapeutic strategies have not been as successful in their treatment. In addition to discussing drawbacks, possible future perspectives to overcome these challenges are also examined. Chapters also focus on therapeutic efficacy and drug delivery systems, providing readers with a full summary of research in this field in one handy reference. Summarizes the therapeutic efficacy of turmeric and curcumin for neurodegenerative diseases Includes effects on Alzheimer’s, Parkinson’s and liver diseases Focuses on different types of drug delivery systems and their challenges Examines novel nanotechnological therapeutics and biomaterial design strategies

Download or read book Curcumin and Neurodegenerative Diseases written by Mahendra Rai and published by Springer. This book was released on 2024-03-09 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores the potential benefits of turmeric, and specifically curcumin, in the treatment and prevention of neurodegenerative diseases. The book covers various aspects of turmeric, including its traditional use in Ayurveda and Chinese medicine, secondary metabolites, curcuminoids, and sesquiterpenoids found in turmeric, as well as the use of nano curcumin in neurodegenerative diseases. It discusses the different ways in which turmeric can be used to treat neurodegenerative diseases, including as a therapy for brain diseases, curcumin-induced neuroprotection in cerebral ischemia, and neural stem cell therapy in combination with curcumin. It also discusses the role of nano curcumin in neurodegenerative diseases, including its potential use in the treatment of Alzheimer's disease. The book provides the scientific evidence behind the use of turmeric and its compounds in the treatment of neurodegenerative diseases, such as Alzheimer's and Parkinson's disease. Overall, this book is an invaluable resource for researchers and healthcare professionals interested in exploring the potential benefits of turmeric and curcumin in the treatment and prevention of neurodegenerative diseases.

Download or read book Curcumin for Neurological and Psychiatric Disorders written by Tahira Farooqui and published by Academic Press. This book was released on 2019-03-16 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: Curcumin for Neurological and Psychiatric Disorders: Neurochemical and Pharmacological Properties focuses on the different molecular mechanisms underlying curcumin-mediated beneficial effects in neurological diseases. The book's editors discuss the neurochemical and pharmacological properties of curcumin, followed by the effect of curcumin in neurotraumatic diseases, neurodegenerative diseases, and neuropsychiatric diseases. The book also offers a perspective on future studies on the treatment of neurological disorders. The beneficial effects of curcumin have been observed both in cultured cells and in animal models, thus paving the way for ongoing present and future human clinical trials. Curcumin produces antioxidant and anti-inflammatory effects not only by blocking oxidative stress and neuroinflammation in neurotraumatic and neurodegenerative diseases, but also by restoring cellular homeostasis and rebalancing redox equilibrium. Identifies molecular mechanisms of curcumin effects in neurological diseases Includes effects on neurotraumatic, neurodegenerative and psychiatric diseases Covers the antioxidant, anti-inflammatory and immunomodulatory effects of curcumin Examines curcumin’s potential in developing new therapeutic drugs

Download or read book Therapeutic Potentials of Curcumin for Alzheimer Disease written by Akhlaq A Farooqui and published by Springer. This book was released on 2016-03-05 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first book on the market that explores the importance of curcumin for the treatment of neurological disorders. It has been estimated that 35.6 million people globally had dementia in 2010 and the prevalence of dementia has been predicted to double every 20 years. Thus, 115.4 million people may be living with dementia in 2050. Alzheimer’s disease (AD) is the leading cause of dementia and is present in 60%–70% of people with dementia. Unless new discoveries are made in the prevention or treatment of AD, the number of cases in the US alone is estimated to increase threefold, to 13.2 million by the year 2050. Thus, it is important to focus on delaying and treating the onset of AD by curcumin may be an important step for controlling AD. Regular consumption of healthy diet containing curcumin enriched foods, moderate exercise, and regular sleep may produce beneficial effects not only on motor and cognitive functions, but also on memory deficits that occur to some extent during normal aging and to a large extent in AD. Delaying the onset and progression of AD and improving its symptoms by few years with regular consumption of curcumin may relieve some of the burden on health care systems. In service of this goal, this volume gives readers a comprehensive and cutting edge description of the importance of curcumin for the treatment of AD in cell culture and animal models in a manner that is useful not only to students and teachers but also to researchers, dietitians, nutritionists and physicians. It can be used as supplement text for a range of neuroscience and nutrition courses. Clinicians, neuroscientists, neurologists and pharmacologists will find this book useful for understanding molecular aspects of AD treatment by curcumin.

Download or read book Oxidative Stress and Neurodegenerative Disorders written by G. Ali Qureshi and published by Elsevier. This book was released on 2007-03-22 with total page 795 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oxidative stress is the result of an imbalance in pro-oxidant/antioxidant homeostasis that leads to the generation of toxic reactive oxygen species. Brain cells are continuously exposed to reactive oxygen species generated by oxidative metabolism, and in certain pathological conditions defense mechanisms against oxygen radicals may be weakened and/or overwhelmed. DNA is a potential target for oxidative damage, and genomic damage can contribute to neuropathogenesis. It is important therefore to identify tools for the quantitative analysis of DNA damage in models on neurological disorders. This book presents detailed information on various neurodegenerative disorders and their connection with oxidative stress. This information will provide clinicians with directions to treat these disorders with appropriate therapy and is also of vital importance for the drug industries for the design of new drugs for treatment of degenerative disorders. * Contains the latest information on the subject of neurodegenerative disorders* Reflects on various factors involved in degeneration and gives suggestions for how to tackle these problems

Download or read book The Benefits of Natural Products for Neurodegenerative Diseases written by M. Mohamed Essa and published by Springer. This book was released on 2016-09-20 with total page 497 pages. Available in PDF, EPUB and Kindle. Book excerpt: Focuses on the effects of natural products and their active components on brain function and neurodegenerative disease prevention. Phytochemicals such as alkaloids, terpenes, flavanoids, isoflavones, saponins etc are known to possess protective activity against many neurological diseases. The molecular mechanisms behind the curative effects rely mainly on the action of phytonutrients on distinct signaling pathways associated with protein folding and neuro-inflammation. The diverse array of bioactive nutrients present in these natural products plays a pivotal role in prevention and cure of various neurodegenerative diseases, disorders, or insults, such as Alzheimer's Disease, Parkinson's Disease, Huntington's Disease, traumatic brain injury, and other neuronal dysfunctions. However, the use of these antioxidants in the management of neurodegenerative conditions has so far been not well understood. This is a comprehensive collection addressing the effects on the brain of natural products and edible items such as reservatrol, curcumin, gingerol, fruits, vegetables, nuts, and marine products.

Download or read book Curcumin written by Daniel Loïc Pouliquen and published by . This book was released on 2014-01-01 with total page 548 pages. Available in PDF, EPUB and Kindle. Book excerpt: Examples of plant-derived pharmaceuticals that have become the focus of continuous and exponential research and development interest have, to date, been somewhat scarce. After a long period, the last two decades have been characterized by a 100-fold increase in the number of scientific articles published annually that are of relevance to the use of curcumin in biomedicine. Today, the already-wide spectrum of potential clinical applications of this natural drug and its synthetic derivatives continues to grow, including chemoprevention and the treatment of cancers, inflammatory and immune diseases, diabetes, bacterial and viral infections, parasitosis, and cardiovascular and neurodegenerative diseases. Over the last two decades, numerous findings have confirmed the safety of curcumin, both in preclinical and clinical studies. Its physicochemical properties, low bioavailability and rapid metabolism have, however, somewhat limited its potential therapeutic applications. To overcome these limitations, the last few years have seen an impressive development of research on analogs, prodrugs and nanostructured systems, a number of which are already demonstrating improved properties compared with the parent structure. In parallel, new administration routes have been explored, and additional pharmacological properties have been documented, leading in particular to promising prospects for pain management.

Download or read book Curcumin written by Daniel Loïc Pouliquen and published by Nova Science Publishers. This book was released on 2014-07-26 with total page 527 pages. Available in PDF, EPUB and Kindle. Book excerpt: Examples of plant-derived pharmaceuticals that have become the focus of continuous and exponential research and development interest have, to date, been somewhat scarce. After a long period, the last two decades have been characterized by a 100-fold increase in the number of scientific articles published annually that are of relevance to the use of curcumin in biomedicine. Today, the already-wide spectrum of potential clinical applications of this natural drug and its synthetic derivatives continues to grow, including chemoprevention and the treatment of cancers, inflammatory and immune diseases, diabetes, bacterial and viral infections, parasitosis, and cardiovascular and neurodegenerative diseases. Over the last two decades, numerous findings have confirmed the safety of curcumin, both in preclinical and clinical studies. Its physicochemical properties, low bioavailability and rapid metabolism have, however, somewhat limited its potential therapeutic applications. To overcome these limitations, the last few years have seen an impressive development of research on analogs, prodrugs and nanostructured systems, a number of which are already demonstrating improved properties compared with the parent structure. In parallel, new administration routes have been explored, and additional pharmacological properties have been documented, leading in particular to promising prospects for pain management.

Download or read book Neurotrophic Factors written by Gary R. Lewin and published by Springer Science & Business Media. This book was released on 2014-03-25 with total page 514 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides critical reviews of the role of neurotrophins and their receptors in a wide variety of diseases including neurodegenerative diseases like Huntington’s syndrome, cognitive function, psychiatric disorders such as clinical depression, Rett syndrome, motoneurone disease, spinal cord injury, pain, metabolic disease and cardiovascular disease. It also contains contributions from leaders in the field dealing with the basic biology, transcriptional and post-translational regulation of the neurotrophins and their receptors. The present book will review all recent areas of progress in the study of neurotrophins and their biological roles.

Download or read book Natural Products and Neuroprotection written by Cristina Angeloni and published by MDPI. This book was released on 2020-06-17 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurodegenerative diseases, including Alzheimer’s, Parkinson’s, Huntington’s, and amyotrophic lateral sclerosis, are the most common pathologies of the central nervous system currently without a cure. They share common molecular and cellular characteristics, including protein misfolding, mitochondrial dysfunction, glutamate toxicity, dysregulation of calcium homeostasis, oxidative stress, inflammation, and ageing, which contribute to neuronal death. Efforts to treat these diseases are often limited by their multifactorial etiology. Natural products, thanks to their multitarget activities, are considered promising alternatives for the treatment of neurodegeneration. This book deals with two different forms of natural products: extracts and isolated compounds. The study of the bioactivity of the extracts is extremely important as many studies have demonstrated the synergistic effect of the combination of different natural products. On the other hand, the investigation of the activity of specifically isolated natural products can be also important to understand their cellular and molecular mechanisms and to define the specific bioactive components in extracts or foods. This book can be considered an important contribution to knowledge of the neuroprotective effect of natural products and presents a great deal of information, related to both the benefits but also the limitations of their use in counteracting neurodegeneration.

Download or read book Neuroprotection in Alzheimer s Disease written by Illana Gozes and published by Academic Press. This book was released on 2016-12-30 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuroprotection in Alzheimer’s Disease offers a translational point-of-view from both basic and clinical standpoints, putting it on the cusp for further clinical development with its emphasis on nerve cell protection, including the accumulation of knowledge from failed clinical trials and new advances in disease management. This book brings together the latest findings, both basic, and clinical, under the same cover, making it easy for the reader to obtain a complete overview of the state-of-the-field and beyond. Alzheimer's disease is the most common form of dementia, accounting for 60 to 80 percent of dementia cases. It is a progressive brain disease that slowly destroys memory, thinking skills, and eventually, even the ability to carry out the simplest tasks. It is characterized by death of synapses coupled to death nerve cells and brain degeneration which is manifested by loss of cognitive abilities. Understanding neuroprotection in Alzheimer’s disease will pave the path to better disease management and novel therapeutics. Comprehensive reference detailing neuroprotection in Alzheimer’s Disease, with details on nerve cell protection and new advances in disease management Combines the knowledge and points-of-view of both medical doctors and basic scientists, putting the subject at the forefront for further clinical development Edited by one of the leading researchers in Alzheimer’s Disease

Download or read book Turmeric Curcumin for Alzheimer s Disease written by Sylvester John and published by . This book was released on 2019-11-22 with total page 96 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Curcuma longa plant belongs to the ginger family (Zingiberaceae) of herbs originating in Southeast Asia. This surprise spice, higher called turmeric or curcumin, performed a substantial function in Ayurvedic medicine for hundreds of years.The concept is going like this-if we will reduce beta-amyloid (Abeta) and tau accumulation inside the brain, Alzheimer's patients could be a lot higher off. There can also even be ability to reverse some of the damage in positive times.However, given that chronic infection has emerged as a trademark of Alzheimer's development, we want something which could tackle both issues immediately.Significant studies has shown that curcumin possesses strong anti-inflammatory houses which could improve continual neuroinflammation. Turmeric dietary supplements also decorate the body's antioxidant pastime, which allows reduce oxidative pressure related to amyloidosis progression.In this book, we can examine the studies surrounding curcumin's functionality to assist in the treatment and prevention of Alzheimer's ailment and dementia.Today, researchers have located an abundance of useful medicinal packages for those effective curcuminoids. From treating arthritis to improving intellectual well being, it looks as if curcumin's listing of fitness blessings is endless. But, can turmeric assist in the treatment and prevention of Alzheimer's sickness (AD) and other sorts of dementia?

Download or read book Neuroprotective Effects of Phytochemicals in Neurological Disorders written by Tahira Farooqui and published by John Wiley & Sons. This book was released on 2017-03-20 with total page 662 pages. Available in PDF, EPUB and Kindle. Book excerpt: Phytochemicals are naturally occurring bioactive compounds found in edible fruits, plants, vegetables, and herbs. Unlike vitamins and minerals, phytochemicals are not needed for the maintenance of cell viability, but they play a vital role in protecting neural cells from inflammation and oxidative stress associated with normal aging and acute and chronic age-related brain diseases. Neuroprotective Effects of Phytochemicals in Neurological Disorders explores the advances in our understanding of the potential neuroprotective benefits that these naturally occurring chemicals contain. Neuroprotective Effects of Phytochemicals in Neurological Disorders explores the role that a number of plant-based chemical compounds play in a wide variety of neurological disorders. Chapters explore the impact of phytochemicals on neurotraumatic disorders, such as stroke and spinal cord injury, alongside neurodegenerative diseases such as Alzheimer's and Parkinson's Disease, as well as neuropsychiatric disorders such as depression and schizophrenia. The chapters and sections of this book provide the reader with a big picture view of this field of research. Neuroprotective Effects of Phytochemicals in Neurological Disorders aims to present readers with a comprehensive and cutting edge look at the effects of phytochemicals on the brain and neurological disorders in a manner useful to researchers, neuroscientists, clinical nutritionists, and physicians.

Download or read book Turmeric written by P. N. Ravindran and published by CRC Press. This book was released on 2007-03-01 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt: For the last 6000 years turmeric has been used in Ayurvedic medicine to alleviate pain, balance digestion, purify body and mind, clear skin diseases, expel phlegm, and invigorate the blood. Nowadays, this plant has acquired great importance with its anti-aging, anti-cancer, anti-Altzheimer, antioxidant, and a variety of other medicinal properties.

Download or read book The Molecular Targets and Therapeutic Uses of Curcumin in Health and Disease written by Bharat B. Aggarwal and published by Springer Science & Business Media. This book was released on 2007-08-06 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt: The medicinal uses of Curcumin (also called turmeric) have been known and described for more than 5000 years. A large body of recent research suggests that curcumin is potentially useful in the treatment of inflammatory diseases, through modulation of numerous molecular targets. This is the first monograph to focus on the potential use of curcumin in the treatment of cancer, diabetes, cardiovascular diseases, arthritis, Alzheimer’s, psoriasis and more.

Download or read book Antioxidants in Food Vitamins and Supplements written by Amitava Dasgupta and published by Academic Press. This book was released on 2014-02-11 with total page 359 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antioxidants in Food, Vitamins and Supplements bridges the gap between books aimed at consumers and technical volumes written for investigators in antioxidant research. It explores the role of oxidative stress in the pathophysiology of various diseases as well as antioxidant foods, vitamins, and all antioxidant supplements, including herbal supplements. It offers healthcare professionals a rich resource of key clinical information and basic scientific explanations relevant to the development and prevention of specific diseases. The book is written at an intermediate level, and can be easily understood by readers with a college level chemistry and biology background. Covers both oxidative stress-induced diseases as well as antioxidant-rich foods (not the chemistry of antioxidants) Contains easy-to-read tables and figures for quick reference information on antioxidant foods and vitamins Includes a glycemic index and a table of ORAC values of various fruits and vegetables for clinicians to easily make recommendations to patients

Download or read book Nutrition and Traumatic Brain Injury written by Institute of Medicine and published by National Academies Press. This book was released on 2011-07-01 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt: Traumatic brain injury (TBI) accounts for up to one-third of combat-related injuries in Iraq and Afghanistan, according to some estimates. TBI is also a major problem among civilians, especially those who engage in certain sports. At the request of the Department of Defense, the IOM examined the potential role of nutrition in the treatment of and resilience against TBI.