Download or read book Stakeholder Engagement Clinical Research Cases written by R. Edward Freeman and published by Springer. This book was released on 2017-09-18 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers a case-study approach to stakeholder theory that moves beyond theoretical analysis to the applied. As stakeholder theory has moved into the mainstream of management thinking in business ethics and a number of the management disciplines, there is an increasing need to explore the subtleties of stakeholder engagement via examples from practice. The case studies in this volume explore a number of aspects of the idea of stakeholder engagement, via the method of clinical case studies. Edited by leading scholars in the field of business ethics and stakeholder theory, this text affords a solid grounding in theory, brought to new levels of applied understanding of stakeholder engagement.

Download or read book Field Trials of Health Interventions written by Peter G. Smith and published by . This book was released on 2015 with total page 479 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is an open access title available under the terms of a CC BY-NC 4.0 International licence. It is free to read at Oxford Scholarship Online and offered as a free PDF download from OUP and selected open access locations. Before new interventions are released into disease control programmes, it is essential that they are carefully evaluated in field trials'. These may be complex and expensive undertakings, requiring the follow-up of hundreds, or thousands, of individuals, often for long periods. Descriptions of the detailed procedures and methods used in the trials that have been conducted have rarely been published. A consequence of this, individuals planning such trials have few guidelines available and little access to knowledge accumulated previously, other than their own. In this manual, practical issues in trial design and conduct are discussed fully and in sufficient detail, that Field Trials of Health Interventions may be used as a toolbox' by field investigators. It has been compiled by an international group of over 30 authors with direct experience in the design, conduct, and analysis of field trials in low and middle income countries and is based on their accumulated knowledge and experience. Available as an open access book via Oxford Medicine Online, this new edition is a comprehensive revision, incorporating the new developments that have taken place in recent years with respect to trials, including seven new chapters on subjects ranging from trial governance, and preliminary studies to pilot testing.

Download or read book Pragmatic Randomized Clinical Trials written by Cynthia J. Girman and published by Academic Press. This book was released on 2021-04-08 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pragmatic Randomized Clinical Trials Using Primary Data Collection and Electronic Health Records addresses the practical aspects and challenges of the design, implementation, and dissemination of pragmatic randomized trials, also sometimes referred to as practical or hybrid randomized trials. While less restrictive and more generalizable than traditional randomized controlled trials, such trials have specific challenges which are addressed in this book. The book contains chapters encompassing common designs along with advantages and limitations of such designs, analytic aspects in planning trials and estimating sample size, and how to use patient partners to help design and operationalize pragmatic randomized trials. Pragmatic trials conducted using primary data collection and trials embedded in electronic health records - including electronic medical records and administrative insurance claims - are addressed.This comprehensive resource is valuable not only for pharmacoepidemiologists, biostatisticians and clinical researchers, but also across the biomedical field for those who are interested in applying pragmatic randomized clinical trials in their research. - Addresses typical designs and challenges of pragmatic randomized clinical trials (pRCTs) - Encompasses analytic aspects of such trials - Discusses real cases on operational challenges in launching and conducting pRCTs in electronic health records

Download or read book Neuroscience Trials of the Future written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2016-11-07 with total page 111 pages. Available in PDF, EPUB and Kindle. Book excerpt: On March 3-4, 2016, the National Academies of Sciences, Engineering, and Medicine's Forum on Neuroscience and Nervous System Disorders held a workshop in Washington, DC, bringing together key stakeholders to discuss opportunities for improving the integrity, efficiency, and validity of clinical trials for nervous system disorders. Participants in the workshop represented a range of diverse perspectives, including individuals not normally associated with traditional clinical trials. The purpose of this workshop was to generate discussion about not only what is feasible now, but what may be possible with the implementation of cutting-edge technologies in the future.

Download or read book Public Engagement and Clinical Trials written by Institute of Medicine and published by National Academies Press. This book was released on 2012-03-17 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical trials provide essential information needed to turn basic medical research findings into patient treatments. New treatments must be studied in large numbers of humans to find out whether they are effective and to assess any harm that may arise from treatment. There is growing recognition among many stakeholders that the U.S. clinical trials enterprise is unable to keep pace with the national demand for research results. The IOM, along with the Mount Sinai School of Medicine, held a workshop June 27-28, 2011, to engage stakeholders and experts in a discussion about possible solutions to improve public engagement in clinical trials.

Download or read book Learning Through Life s Trials written by Larry Richman and published by . This book was released on 2007-11-01 with total page 32 pages. Available in PDF, EPUB and Kindle. Book excerpt: "You can choose to see a trial as a roadblock or an expressway. If you see it as a roadblock, it will obstruct your way. However, if you see it as an expressway, you can use it to learn and grow." "The gospel of Jesus Christ is the plan whereby we can become what God wants us to become. In fact, we become great people because of our trials, not in spite of them." This booklet reviews the nature, origins, and purposes of adversity and includes suggestions on how to patiently trust in the Lord and His eternal plan and how to use these trials to learn and grow stronger. You can benefit from your trials if you: Develop a relationship with God Let others help you Let God carry your burdens Trust that the Lord is in control and allow His will to be done Remember that everyone has challenges Let adversity make you a better person Live with integrity Be patient Make the best of your situation Serve others Keep a positive attitude Keep an eternal perspective

Download or read book Trial Engagement written by Barbara McMahon and published by Harlequin. This book was released on 2011-07-15 with total page 149 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fake fiancée! It was Mike Black's job to keep Candee safe until she testified in court. But his idea of protection meant hiding out with her at his brother's ranch and pretending she was his fiancée! Candee was not impressed—she was a city girl, and confinement in the country was not her idea of fun. The only compensation was living with Mike, but he knew better than to get involved with an irresistible, bubbly blonde. Past experience had taught him it could only lead to one thing: trouble!

Download or read book Digital Mental Health Research Understanding Participant Engagement and Need for User centered Assessment and Interventional Digital Tools written by Abhishek Pratap and published by Frontiers Media SA. This book was released on 2023-08-15 with total page 179 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mental health researchers are increasingly looking towards digital health tools to gather day-to-day lived experiences of people living with mental health conditions, by using apps and wearable devices complementing episodic clinical assessments. One of the key goals of collecting longitudinal real-world multimodal data (RWD) is to help build personalized computational models that may help explain the heterogeneity in clinical outcomes, mechanisms of action, and pathophysiology of mental health disorders across individuals.

Download or read book Technical Report written by and published by . This book was released on 1979 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Oncology Clinical Trials written by William Kevin Kelly, DO and published by Springer Publishing Company. This book was released on 2018-03-28 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of Oncology Clinical Trials has been thoroughly revised and updated and now contains the latest designs and methods of conducting and analyzing cancer clinical trials in the era of precision medicine with biologic agents—including trials investigating the safety and efficacy of targeted therapies, immunotherapies, and combination therapies as well as novel radiation therapy modalities. Now divided into six sections this revamped book provides the necessary background and expert guidance from the principles governing oncology clinical trials to the innovative statistical design methods permeating the field; from conducting trials in a safe and effective manner, analyzing and interpreting the data, to a forward-looking assessment and discussion of regulatory issues impacting domestic, international, and global clinical trials. Considered by many as the gold standard reference on oncology clinical trials in the field, the second edition continues to provide examples of real-life flaws and real-world examples for how to successfully design, conduct and analyze quality clinical trials and interpret them. With chapters written by oncologists, researchers, biostatisticians, clinical research administrators, and industry and FDA representatives, this volume provides a comprehensive guide in the design, conduct, monitoring, analysis, and reporting of clinical trials in oncology. NEW TO THIS EDITION: Outlines how to design clinical trials with and without biomarker testing—including genomics-based “basket” trials, and adaptive trials for all phases during treatment and quality-of-life trials Includes new chapters on immunotherapy trials, radiation therapy trials, multi-arm trials, meta-analysis and adaptive design, use of genomics, dose modifications and use of ancillary treatments in investigational studies, establishing surrogate endpoints, practical issues with correlative studies, cost-effectiveness analysis, and more Comprehensively covers all regulatory aspects in the pursuit of global oncology trials Digital access to the ebook included

Download or read book The Vaccine Book written by Barry R. Bloom and published by Academic Press. This book was released on 2016-06-23 with total page 666 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Vaccine Book, Second Edition provides comprehensive information on the current and future state of vaccines. It reveals the scientific opportunities and potential impact of vaccines, including economic and ethical challenges, problems encountered when producing vaccines, how clinical vaccine trials are designed, and how to introduce vaccines into widespread use. Although vaccines are now available for many diseases, there are still challenges ahead for major diseases, such as AIDS, tuberculosis, and malaria. This book is designed for students, researchers, public health officials, and all others interested in increasing their understanding of vaccines. It answers common questions regarding the use of vaccines in the context of a rapidly expanding anti-vaccine environment. This new edition is completely updated and revised with new and unique topics, including new vaccines, problems of declining immunization rates, trust in vaccines, the vaccine hesitancy, and the social value of vaccines for the community vs. the individual child's risk. - Provides insights into diseases that could be prevented, along with the challenges facing research scientists in the world of vaccines - Gives new ideas about future vaccines and concepts - Introduces new vaccines and concepts - Gives ideas about challenges facing public and private industrial investors in the vaccine area - Discusses the problem of declining immunization rates and vaccine hesitancy

Download or read book Broadly Engaged Team Science in Clinical and Translational Research written by Debra Lerner and published by Springer Nature. This book was released on 2022-02-27 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite the large U.S. investment in health science, and the vast and growing body of peer-reviewed research findings it has produced, a compelling body of evidence suggests that research too often has been slow, inefficient, and fallen short of desired impacts on health. A key question is how research might be changed to be more innovative, less wasteful, and more responsive to unmet health needs. One emerging response within clinical and translational science is to advance an approach that attempts to close the gap between research scientists and key stakeholders; the individuals and groups responsible for or affected by health-related decisions. Broadly engaged team science promises to support this aim by transforming the gold standard, multi-disciplinary team science, to include key stakeholders in activities across the research spectrum. These new roles and responsibilities range from generating research questions to implementing research projects, to aiding in the translation of discoveries from the laboratory to the community. A transition to broadly engaged team science reflects the idea that inclusivity and a diversity of perspectives are necessary to achieving progress in addressing complex health issues while representing a new benchmark for ethical research practice. This is one of the first collections of papers describing how clinical and translational science researchers are defining and implementing new research practices, and the successes and challenges involved. This book represents a first and critical step towards organizing knowledge of broadly engaged team science and advancing the development of evidence-based practices. Written in an accessible style, this book is intended to highlight the breadth of broadly engaged team science within one community, motivate researchers and stakeholders to build inclusive teams, bring rigor to often informal stakeholder engagement research practices and encourage people to think more broadly about the development of scientific knowledge. It includes examples of multi-disciplinary, broadly engaged team science projects, the perspectives of academic leaders about the changes needed to encourage scientists to conduct broadly engaged team science, and a resource directory.

Download or read book More Than the Tattooed Mormon Limited Second Edition Hardcover written by Al Carraway and published by Cfi. This book was released on 2018-03 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Al Fox Carraway has inspired the world with her message of conversion, redemption, and finding faith. As a blogger and award-winning public speaker, her voice has reached millions. Now you can own this second edition of her best-selling autobiograpy, featuring two brand new chapters from Al. Learn from her story what it means to truly trust in the Lord.

Download or read book Rules of Engagement written by Derek Prince and published by Baker Books. This book was released on 2012-08-01 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vital Teaching on an Imperative, Timeless Topic from Derek Prince Now updated and expanded, with several brand-new chapters and reflection questions following every chapter, this landmark text offers the most important and practical guidance Derek Prince imparted to believers in his last years: how to prepare for and take their places in the ultimate, ongoing spiritual battle. With superb biblical exposition and hands-on application, Prince explains that Christians need to be more than just disciples; they need to be warriors. He shows them how to build a warrior's character, to face testing, to fight alongside the Holy Spirit, to influence the outcomes of spiritual battles, and more. With this manual in hand, believers will learn how to fulfill their roles confidently in both day-to-day trials and in God's plan for the finale of the ages.

Download or read book Eye Movements and Visual Cognition written by Raymond M. Klein and published by MDPI. This book was released on 2020-12-29 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a volume based on the “Eye Movements and Visual Cognition” Special Issue published in the journal Vision by MDPI and edited by Raymond Klein and Simon Liversedge. The eBook comprises 19 high-quality chapters that are original and topical works by leading academic figures in the field of human vision and visual cognition. In putting together the book, we aimed to provide an informative body of work to stimulate and foster useful intellectual exchange between individuals working on basic theoretical issues as well as on more applied aspects of vision and cognitive science. From the outset, we sought papers that provide concise and astute reviews of topics within this broad field. The present volume includes reviews that are narrative (critiquing and summarizing research on a topic), tutorial (with a focus on methods and findings), empirical (e.g., meta-analytic), and theoretically synthetic. The eBook also features chapters with new empirical content that resolves an undecided issue stemming from an evaluation of the literature. Finally, where possible, we also selected papers that bridge theoretical and applied issues and provide insight into behavior and its neural substrate. All chapters were subject to peer review and went through several rounds of revision prior to acceptance.

Download or read book Ethics and adaptive platform trial design in public health emergencies written by World Health Organization and published by World Health Organization. This book was released on 2023-10-03 with total page 24 pages. Available in PDF, EPUB and Kindle. Book excerpt: Platform trials, using adaptive methodologies, have played an important role in the research response to COVID-19, and offer prospect of being widely used in future pandemic preparedness and response. As these relatively new methodologies raise a number of ethical and governance challenges, in early 2022 the Health Ethics and Governance Unit of the World Health Organization commissioned five rapid reviews, with the aim of learning from, and building on, experiences during the pandemic. These reviews covered the role and policy impact of adaptive platform trials during COVID-19 https://www.who.int/teams/health-ethics-governance/emergencies-and-outbreaks/platform-trials. The target audiences: the research community, including researchers, research funders, ministries of health and science, research ethics committee and regulators.

Download or read book Alzheimer s Disease Drug Development written by Jeffrey Cummings and published by Cambridge University Press. This book was released on 2022-03-31 with total page 575 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alzheimer's Disease (AD) is a growing global public health challenge. The development of new therapies is urgently needed, and a complex ecosystem of organizations has grown to facilitate AD drug discovery and development. Masterfully collating information on the drug development ecosystem, this book emphasizes the contributions of each aspect in the pipeline with a uniform approach to chapters, enabling readers to access relevant information quickly. Topics covered include the use of non-clinical laboratory studies, biomarker development, artificial intelligence, design and management of clinical trials, and funding and financing models. Also discussed is the critical role of advocacy fundraising for drug development. With the approval of aducanumab, the function of the ecosystem has become apparent. This is a definitive overview of how the ecosystem works in transferring an AD drug from its discovery in the laboratory through clinical trial testing to regulatory review and eventual marketing.