Download or read book Math on Trial written by Leila Schneps and published by Basic Books. This book was released on 2013-03-12 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the wrong hands, math can be deadly. Even the simplest numbers can become powerful forces when manipulated by politicians or the media, but in the case of the law, your liberty -- and your life -- can depend on the right calculation. In Math on Trial, mathematicians Leila Schneps and Coralie Colmez describe ten trials spanning from the nineteenth century to today, in which mathematical arguments were used -- and disastrously misused -- as evidence. They tell the stories of Sally Clark, who was accused of murdering her children by a doctor with a faulty sense of calculation; of nineteenth-century tycoon Hetty Green, whose dispute over her aunt's will became a signal case in the forensic use of mathematics; and of the case of Amanda Knox, in which a judge's misunderstanding of probability led him to discount critical evidence -- which might have kept her in jail. Offering a fresh angle on cases from the nineteenth-century Dreyfus affair to the murder trial of Dutch nurse Lucia de Berk, Schneps and Colmez show how the improper application of mathematical concepts can mean the difference between walking free and life in prison. A colorful narrative of mathematical abuse, Math on Trial blends courtroom drama, history, and math to show that legal expertise isn't't always enough to prove a person innocent.
Download or read book Resources in Education written by and published by . This book was released on 1995-12 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Clinical Trials written by Steven Piantadosi and published by John Wiley & Sons. This book was released on 2017-10-06 with total page 1064 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents elements of clinical trial methods that are essential in planning, designing, conducting, analyzing, and interpreting clinical trials with the goal of improving the evidence derived from these important studies This Third Edition builds on the text’s reputation as a straightforward, detailed, and authoritative presentation of quantitative methods for clinical trials. Readers will encounter the principles of design for various types of clinical trials, and are then skillfully guided through the complete process of planning the experiment, assembling a study cohort, assessing data, and reporting results. Throughout the process, the author alerts readers to problems that may arise during the course of the trial and provides common sense solutions. All stages of therapeutic development are discussed in detail, and the methods are not restricted to a single clinical application area. The authors bases current revisions and updates on his own experience, classroom instruction, and feedback from teachers and medical and statistical professionals involved in clinical trials. The Third Edition greatly expands its coverage, ranging from statistical principles to new and provocative topics, including alternative medicine and ethics, middle development, comparative studies, and adaptive designs. At the same time, it offers more pragmatic advice for issues such as selecting outcomes, sample size, analysis, reporting, and handling allegations of misconduct. Readers familiar with the First and Second Editions will discover revamped exercise sets; an updated and extensive reference section; new material on endpoints and the developmental pipeline, among others; and revisions of numerous sections. In addition, this book: • Features accessible and broad coverage of statistical design methods—the crucial building blocks of clinical trials and medical research -- now complete with new chapters on overall development, middle development, comparative studies, and adaptive designs • Teaches readers to design clinical trials that produce valid qualitative results backed by rigorous statistical methods • Contains an introduction and summary in each chapter to reinforce key points • Includes discussion questions to stimulate critical thinking and help readers understand how they can apply their newfound knowledge • Provides extensive references to direct readers to the most recent literature, and there are numerous new or revised exercises throughout the book Clinical Trials: A Methodologic Perspective, Third Edition is a textbook accessible to advanced undergraduate students in the quantitative sciences, graduate students in public health and the life sciences, physicians training in clinical research methods, and biostatisticians and epidemiologists. This book is accompanied by downloadable files available below under the DOWNLOADS tab. These files include: MATHEMATICA program – A set of downloadable files that tracks the chapters, containing code pertaining to each. SAS PROGRAMS and DATA FILES used in the book. The following software programs, included in the downloadables, were developed by the author, Steven Piantadosi, M.D., Ph.D: RANDOMIZATION – This program generates treatment assignments for a clinical trial using blocked stratified randomization. CRM – Implements the continual reassessment methods for dose finding clinical trials. OPTIMAL – Calculates two-stage optimal phase II designs using the Simon method. POWER – This is a power and sample size program for clinical trials. Executables for installing these programs can also be found at https://risccweb.csmc.edu/biostats/. Steven Piantadosi, MD, PhD, is the Phase One Foundation Distinguished Chair and Director of the Samuel Oschin Cancer Institute, and Professor of Medicine at Cedars-Sinai Medical Center in Los Angeles, California. Dr. Piantadosi is one of the world’s leading experts in the design and analysis of clinical trials for cancer research. He has taught clinical trials methods extensively in formal courses and short venues. He has advised numerous academic programs and collaborations nationally regarding clinical trial design and conduct, and has served on external advisory boards for the National Institutes of Health and other prominent cancer programs and centers. The author of more than 260 peer-reviewed scientific articles, Dr. Piantadosi has published extensively on research results, clinical applications, and trial methodology. While his papers have contributed to many areas of oncology, he has also collaborated on diverse studies outside oncology including lung disease and degenerative neurological disease.
Download or read book Cybersecurity and Applied Mathematics written by Leigh Metcalf and published by Syngress. This book was released on 2016-06-07 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cybersecurity and Applied Mathematics explores the mathematical concepts necessary for effective cybersecurity research and practice, taking an applied approach for practitioners and students entering the field. This book covers methods of statistical exploratory data analysis and visualization as a type of model for driving decisions, also discussing key topics, such as graph theory, topological complexes, and persistent homology. Defending the Internet is a complex effort, but applying the right techniques from mathematics can make this task more manageable. This book is essential reading for creating useful and replicable methods for analyzing data. - Describes mathematical tools for solving cybersecurity problems, enabling analysts to pick the most optimal tool for the task at hand - Contains numerous cybersecurity examples and exercises using real world data - Written by mathematicians and statisticians with hands-on practitioner experience
Download or read book Methods and Applications of Statistics in Clinical Trials Volume 1 written by Narayanaswamy Balakrishnan and published by John Wiley & Sons. This book was released on 2014-03-05 with total page 937 pages. Available in PDF, EPUB and Kindle. Book excerpt: A complete guide to the key statistical concepts essential for the design and construction of clinical trials As the newest major resource in the field of medical research, Methods and Applications of Statistics in Clinical Trials, Volume 1: Concepts, Principles, Trials, and Designs presents a timely and authoritative reviewof the central statistical concepts used to build clinical trials that obtain the best results. The referenceunveils modern approaches vital to understanding, creating, and evaluating data obtained throughoutthe various stages of clinical trial design and analysis. Accessible and comprehensive, the first volume in a two-part set includes newly-written articles as well as established literature from the Wiley Encyclopedia of Clinical Trials. Illustrating a variety of statistical concepts and principles such as longitudinal data, missing data, covariates, biased-coin randomization, repeated measurements, and simple randomization, the book also provides in-depth coverage of the various trial designs found within phase I-IV trials. Methods and Applications of Statistics in Clinical Trials, Volume 1: Concepts, Principles, Trials, and Designs also features: Detailed chapters on the type of trial designs, such as adaptive, crossover, group-randomized, multicenter, non-inferiority, non-randomized, open-labeled, preference, prevention, and superiority trials Over 100 contributions from leading academics, researchers, and practitioners An exploration of ongoing, cutting-edge clinical trials on early cancer and heart disease, mother-to-child human immunodeficiency virus transmission trials, and the AIDS Clinical Trials Group Methods and Applications of Statistics in Clinical Trials, Volume 1: Concepts, Principles, Trials, and Designs is an excellent reference for researchers, practitioners, and students in the fields of clinicaltrials, pharmaceutics, biostatistics, medical research design, biology, biomedicine, epidemiology,and public health.
Download or read book Applied Mathematics by Example Exercises written by and published by Bookboon. This book was released on with total page 121 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Monthly Catalog of United States Government Publications written by and published by . This book was released on 1992 with total page 978 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Numerical Analysis A Graduate Course written by David E. Stewart and published by Springer Nature. This book was released on 2022-12-01 with total page 645 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book aims to introduce graduate students to the many applications of numerical computation, explaining in detail both how and why the included methods work in practice. The text addresses numerical analysis as a middle ground between practice and theory, addressing both the abstract mathematical analysis and applied computation and programming models instrumental to the field. While the text uses pseudocode, Matlab and Julia codes are available online for students to use, and to demonstrate implementation techniques. The textbook also emphasizes multivariate problems alongside single-variable problems and deals with topics in randomness, including stochastic differential equations and randomized algorithms, and topics in optimization and approximation relevant to machine learning. Ultimately, it seeks to clarify issues in numerical analysis in the context of applications, and presenting accessible methods to students in mathematics and data science.
Download or read book Monthly Catalogue United States Public Documents written by and published by . This book was released on 1992 with total page 982 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book IJER Vol 9 N2 written by International Journal of Educational Reform and published by Rowman & Littlefield. This book was released on 2000-04-01 with total page 89 pages. Available in PDF, EPUB and Kindle. Book excerpt: The mission of the International Journal of Educational Reform (IJER) is to keep readers up-to-date with worldwide developments in education reform by providing scholarly information and practical analysis from recognized international authorities. As the only peer-reviewed scholarly publication that combines authors’ voices without regard for the political affiliations perspectives, or research methodologies, IJER provides readers with a balanced view of all sides of the political and educational mainstream. To this end, IJER includes, but is not limited to, inquiry based and opinion pieces on developments in such areas as policy, administration, curriculum, instruction, law, and research. IJER should thus be of interest to professional educators with decision-making roles and policymakers at all levels turn since it provides a broad-based conversation between and among policymakers, practitioners, and academicians about reform goals, objectives, and methods for success throughout the world. Readers can call on IJER to learn from an international group of reform implementers by discovering what they can do that has actually worked. IJER can also help readers to understand the pitfalls of current reforms in order to avoid making similar mistakes. Finally, it is the mission of IJER to help readers to learn about key issues in school reform from movers and shakers who help to study and shape the power base directing educational reform in the U.S. and the world.
Download or read book Mathematical Modeling of the Learning Curve written by Charles I. Abramson and published by Walter de Gruyter GmbH & Co KG. This book was released on 2024-06-17 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: The application of mathematical models in the analysis of learning data has a rich tradition in experimental psychology. Such modeling is not only of scientific interest from psychophysiological point of view but very important from clinical point of view because memory impairment is a common symptom that is frequently diagnosed in elder people, persons after traumatic brain injury, patients with type 2 diabetes mellitus, Parkinson disease, multiple sclerosis, and other neurological and psychiatric diseases. Mild memory impairment might be one of the most important symptoms of a future Alzheimer's disease. Thus, early diagnosis of initial signs of memory impairment is of importance. The book offers the reader hands on practical experience using a mathematical model dveloped by the senior authors. Classroom tested experiments are provided which requires the reader to use the model under various conditions such as learning and memory in both humans and animals. Following an introduction to mathematical models, the book contains 13 experiments. These experiments include those related to animal learning in such organisms as snails, bees, and rats. A variety of human experiments are also presented including those related to short and long term memory, maze learning, classical salivary conditioning, evaluation of sound on memory, and the influence of dietary supplements on memory. We close the section on experiments with and analysis of machine learning curves. Appendices are provided on how to build apparatus and how to install the software.
Download or read book Applied Finite Mathematics written by and published by . This book was released on 2008 with total page 413 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Planning Pharmaceutical Clinical Trials written by William M. Wooding and published by Wiley-Interscience. This book was released on 1994 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt: Imparts a working understanding of the statistical principles and procedures essential to conducting successful clinical studies. Features a detailed catalog of experimental designs most commonly used in clinical work. Includes two chapters on elementary applied statistics and one on sample size estimation (the number of patients required).
Download or read book Applying social science written by Byrne, David and published by Policy Press. This book was released on 2011-02-16 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: In complex contemporary societies social science has become increasingly interwoven into the whole fabric of governance. At the same time there is an increasing recognition that attempts to understand the social world which seek to mimic the linear approaches of the conventional 'hard sciences' are mostly useless given the complex systems character of society in all its aspects. This book draws on a synthesis of critical realism and complexity theory to examine how social science is applied now and how it might be applied in the future in relation to social transformation in a time of crisis. A central argument is that there is no such thing as a 'pure' science of the social and that a recognition of the inevitability of application imposes obligations on social scientists wherever they work which challenge the passivity of most in the face of inequality and injustice.
Download or read book Austrian Economics Money and Finance written by Thomas Mayer and published by Routledge. This book was released on 2017-11-10 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: The financial crisis has exposed severe shortcomings in mainstream monetary economics and modern finance. It is surprising that these shortcomings have not led to a wider debate about the need to overhaul these theories. Instead, mainstream economists have closed ranks to defend existing theories and public authorities have expanded their interference in markets. This book investigates the problems associated with mainstream monetary economics and finance, and proposes alternatives based on the Austrian school of economics. This school emanated from the work of the nineteenth-century Austrian economist Carl Menger and was developed further by Eugen von Böhm-Bawerk, Ludwig von Mises, and Friedrich August von Hayek. In monetary economics, the Austrian school regards the creation of money by banks through credit extension as a key source of economic instability. From this follows the need for a comprehensive reform of our present monetary system. In a new monetary order, money could be issued by both public and private institutions, and there would be no need for fractional reserve banking. Instead of creating money, banks would intermediate it. In finance, the Austrian school rejects the notion of rational expectations and measurable risk. Individuals use their subjective knowledge to gather and evaluate information, and they act in a world of radical uncertainty. Hence, markets are not "efficient" nor can portfolios be built on the basis of known probability distributions of asset prices as described in the modern finance literature. This book explores the need for a new theoretical foundation for asset pricing and investment management that will give practitioners more useful orientation.
Download or read book Method for Optimizing the Tool and Process Design for Bevel Gear Plunging Processes written by Julia Mazak and published by Apprimus Wissenschaftsverlag. This book was released on 2021-06-17 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: For manufacturing bevel gears, a special tool system consisting of cutterhead and removable blades produces multi-flank chips which are of complex, three-dimensional geometry. The objective of this thesis was to optimize the manufacturing process for continuous and discontinuous plunging for bevel gear cutting regarding tool life based on tool angles and process parameters. For this purpose, a wear model was developed that is based on the elastic deformation of the workpiece.
Download or read book Applied Groundwater Modeling written by Mary P. Anderson and published by Academic Press. This book was released on 2015-08-13 with total page 632 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second edition is extensively revised throughout with expanded discussion of modeling fundamentals and coverage of advances in model calibration and uncertainty analysis that are revolutionizing the science of groundwater modeling. The text is intended for undergraduate and graduate level courses in applied groundwater modeling and as a comprehensive reference for environmental consultants and scientists/engineers in industry and governmental agencies. - Explains how to formulate a conceptual model of a groundwater system and translate it into a numerical model - Demonstrates how modeling concepts, including boundary conditions, are implemented in two groundwater flow codes-- MODFLOW (for finite differences) and FEFLOW (for finite elements) - Discusses particle tracking methods and codes for flowpath analysis and advective transport of contaminants - Summarizes parameter estimation and uncertainty analysis approaches using the code PEST to illustrate how concepts are implemented - Discusses modeling ethics and preparation of the modeling report - Includes Boxes that amplify and supplement topics covered in the text - Each chapter presents lists of common modeling errors and problem sets that illustrate concepts