Download or read book Trends in Medicinal Chemistry 88 written by H. van der Goot and published by Elsevier Publishing Company. This book was released on 1989 with total page 880 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on with total page 1144 pages. Available in PDF, EPUB and Kindle. Book excerpt: First multi-year cumulation covers six years: 1965-70.
Download or read book National Library of Medicine Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on 1988 with total page 1036 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Current Catalog written by and published by . This book was released on 1989 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: First multi-year cumulation covers six years: 1965-70.
Download or read book QSAR and Drug Design New Developments and Applications written by H. Timmerman and published by Elsevier. This book was released on 1995-11-20 with total page 509 pages. Available in PDF, EPUB and Kindle. Book excerpt: Based on topics presented at the Annual Japanese (Quantitative) Structure-Activity Relationship Symposium and the Biennial China-Japan Drug Design and Development conference, the topics in this volume cover almost every procedure and subdiscipline in the SAR discipline.They are categorized in three sections. Section one includes topics illustrating newer methodologies relating to ligand-receptor, molecular graphics and receptor modelling as well as the three-dimensional (Q)SAR examples with the active analogue approach and the comparative molecular field analysis. In section 2 the hydrophobicity parameters, log P (1-octanol/water) for compound series of medicinal-chemical interest are analysed physico-organic chemically. Section 3 contains the examples based on the traditional Hansch QSAR approach.A variety of methodologies and procedures are presented in this single volume, along with their methodological philosophies.
Download or read book Perspectives in Receptor Research written by Dario Giardina and published by Elsevier. This book was released on 1996-06-07 with total page 423 pages. Available in PDF, EPUB and Kindle. Book excerpt: Perspectives in Receptor Research
Download or read book Progress in Medicinal Chemistry written by and published by Elsevier. This book was released on 1998-07-03 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: Eminent scientists at the cutting edge of pharmacology and medicinal chemistry research provide us with yet another excellent addition to this famous series. The focus on bacterial resistance mechanisms serves to highlight an important area of unmet medical need requiring the attention of medicinal chemists. Five topical subjects are reviewed: the biosynthesis, metabolism and function of Vitamin D3 and the potential application of its analogues in bone disorders and immune-related diseases; the therapeutic potential of neurokinin antagonists; opioid receptor antagonists; the mechanisms of bacterial resistance; and a survey of recent advances in cannabinoid research. This volume will deservedly take its place in clinical and industrial pharmaceutical libraries, and will prove invaluable to medicinal chemists.
Download or read book Small Peptides written by A.S. Dutta and published by Elsevier. This book was released on 2013-10-22 with total page 633 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pharmacochemistry Library, Volume 19: Small Peptides: Chemistry, Biology, and Clinical Studies focuses on the processes, reactions, properties, and characteristics of peptides, including analogues and proteases. The publication first takes a look at angiotensin II and bombesin/gastrin-releasing peptide. Topics include conformationally restricted analogues of bombesin, non-peptide antagonists of angiotensin II, receptor subtypes of angiotensin II, and bombesin/GRP antagonists and cancer. The text then elaborates on bradykinin, cholecystokinin, and enkephalin analogues. The manuscript examines luteinizing hormone releasing hormone and somatostatin. Topics include enzymic degradation of somatostatin and analogues, clinical applications of somatostatin analogues, and pharmacological and clinical studies with LHRH agonists and antagonists. The formulation of peptides and inhibitors of aspartyl proteases are also mentioned. The book is a valuable source of information for chemists, biologists, and readers interested in small peptides.
Download or read book The Chemistry and Pharmacology of Taxol and its Derivatives written by H. Timmerman and published by Elsevier. This book was released on 1995-06-16 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: Taxol®, a naturally occurring diterpenoid is one of the most exciting antitumor drugs available today. Its current indications (refractory ovarian and metastatic breast cancer) may soon be expanded since the drug is showing activity against lung and head-and-neck cancers. The book opens with a review of the naturally occurring taxoids, a chapter which is not a comprehensive list of all taxoids isolated to date, but attempts a systematic approact to describing the different classes of taxoids, with particular reference to all skeletal types and the various functionality patterns. Biosynthetic studies are also discussed, as well as some of the basic chemistry and common functionalities of taxoidic skeleton. Structural identification of taxoids, mostly by spectroscopic means; the formulation of taxanes; the metabolism and pharmacokinetics of Taxol® are also discussed, as are the chemistry of taxanes in relation to SAR studies; SAR aspects of the phenylisoserine side chain; and the mode of action of the taxanes and the mechanisms of resistance. The book is therefore written for medical chemists, in order to stimulate further research in this area and to provide the reader with the necessary background information to start a research program in the area.
Download or read book NIDA Research Monograph written by and published by . This book was released on 1976 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Current Pharmaceutical Design written by and published by . This book was released on 1995-08 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Topics in Medicinal Chemistry written by P. R. Leeming and published by . This book was released on 1988 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: This series of Medicinal Chemistry Symposia (established in 1981) aims to present and discuss recent scientific advances relevant to drug discovery. Topics covered in 1987 include neuropeptides, control of enzymatic processes, antiviral agents, avermectins and computational chemistry.
Download or read book Membranes and Barriers written by and published by . This book was released on 1995 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Drug Targeting Technology written by Hans Schreier and published by CRC Press. This book was released on 2001-08-09 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: Demonstrates how substitution of a variety of ligands can render albumin a versatile targeting tool for selective drug accumulation in various cell populations of the liver! This book discusses physical, chemical, and biological approaches to drug targeting technology, focusing on oral, dispersed system, topical, dermal, transdermal, and inh
Download or read book Advances in Drug Research written by Bernard Testa and published by Elsevier. This book was released on 2013-10-22 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Drug Research, Volume 20 focuses on the general themes of drug research and description of specific drug classes. This book is divided into four chapters. Chapter 1 discusses the extrapolation of toxicological and pharmacological data from animals to humans. The second chapter deals with the tissue binding of drugs, considering the relative ponderal importance of tissue versus blood macromolecules. The therapeutic use of plants and consumption of medicinal plants are elaborated in Chapter 3. The last chapter covers the field of histaminergic agonists and antagonists, describing breakthroughs such as H2-receptor antagonists, non-sedating H1-receptor antagonists, and H3-receptors. This publication is valuable to drug researchers and students interested in advances in drugs.
Download or read book Statistical Reference Index written by and published by . This book was released on 1988 with total page 1062 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Synthesis of Heterocycles in Contemporary Medicinal Chemistry written by Zdenko Časar and published by Springer. This book was released on 2016-07-01 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: The series Topics in Heterocyclic Chemistry presents critical reviews on present and future trends in the research of heterocyclic compounds. Overall the scope is to cover topics dealing with all areas within heterocyclic chemistry, both experimental and theoretical, of interest to the general heterocyclic chemistry community. The series consists of topic related volumes edited by renowned editors with contributions of experts in the field. All chapters from Topics in Heterocyclic Chemistry are published Online First with an individual DOI. In references, Topics in Heterocyclic Chemistry is abbreviated as Top Heterocycl Chem and cited as a journal.
