Download or read book Advances in Breast Cancer Management 2nd edition written by William J. Gradishar and published by Springer Science & Business Media. This book was released on 2000-08-31 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: The optimal management of breast cancer patients relies on the expertise of a team of medical specialists including radiologists, surgeons, radiation therapists and medical oncologists. Much of the progress in breast cancer management made over the last several years reflects the translation of observations made in the laboratory to the clinic. Critically evaluating the impact of new treatment approaches relies on a commitment to well-designed clinical trials. In this volume, Advances in Breast Cancer Management, a renowned group of breast cancer experts have been asked to provide their perspective on management issues that directly effect patients on a day-to-day basis. Dr. Melody Cobleigh discusses the consequences of estrogen deprivation and the ways of ameliorating secondary symptoms and the potential long-term morbidity. Drs. Haigh and Guiliano review the sentinel lymph node biopsy technique including results from their extensive experience. Dr. Abram Recht places into perspective the potential benefit of post-mastectomy radiotherapy and reviews recent trials that address this issue. Dr. Dennis Slamon takes from us from the laboratory to the clinic in explaining the development of Herceptin as a paradigm for therapy targeted to specific molecular characteristics of breast cancer tumor cells. Drs. Nieto, Shpall, Crump and Pritchard offer different perspectives on the future of high-dose chemotherapy with stem cell transplantation as a treatment for breast cancer patients. Drs.

Download or read book AJCC Cancer Staging Manual written by Frederick L, Greene and published by Springer Science & Business Media. This book was released on 2013-11-21 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: The American Joint Committee on Cancer's Cancer Staging Manual is used by physicians throughout the world to diagnose cancer and determine the extent to which cancer has progressed. All of the TNM staging information included in this Sixth Edition is uniform between the AJCC (American Joint Committee on Cancer) and the UICC (International Union Against Cancer). In addition to the information found in the Handbook, the Manual provides standardized data forms for each anatomic site, which can be utilized as permanent patient records, enabling clinicians and cancer research scientists to maintain consistency in evaluating the efficacy of diagnosis and treatment. The CD-ROM packaged with each Manual contains printable copies of each of the book’s 45 Staging Forms.

Download or read book Her 2 written by Robert Bazell and published by Random House. This book was released on 2011-04-27 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: Two years after she underwent a mastectomy and chemotherapy, Barbara Bradfield's aggressive breast cancer had recurred and spread to her lungs. The outlook was grim. Then she took part in Genentech's clinical trials for a new drug. Five years later she remains cancer-free. Her-2 is the biography of Herceptin, the drug that provoked dramatic responses in Barbara Bradfield and other women in the trials and that offers promise for hundreds of thousands of breast cancer patients. Unlike chemotherapy or radiation, Herceptin has no disabling side effects. It works by inactivating Her-2/neu--a protein that makes cancer cells grow especially quickly-- produced by a gene found in 25 to 30 percent of all breast tumors. Herceptin caused some patients' cancers to disappear completely; in others, it slowed the progression of the disease and gave the women months or years they wouldn't otherwise have had. Herceptin is the first treatment targeted at a gene defect that gives rise to cancer. It marks the beginning of a new era of treatment for all kinds of cancers. Robert Bazell presents a riveting account of how Herceptin was born. Her-2 is a story of dramatic discoveries and strong personalities, showing the combination of scientific investigation, money, politics, ego, corporate decisions, patient activism, and luck involved in moving this groundbreaking drug from the lab to a patient's bedside. Bazell's deft portraits introduce us to the remarkable people instrumental in Herceptin's history, including Dr. Dennis Slamon, the driven UCLA oncologist who played the primary role in developing the treatment; Lily Tartikoff, wife of television executive Brandon Tartikoff, who tapped into Hollywood money and glamour to help fund Slamon's research; and Marti Nelson, who inspired the activists who lobbied for a "compassionate use" program that would allow women outside the clinical trials to have access to the limited supplies of Herceptin prior to FDA approval of the drug. And throughout there are the stories of the heroic women with advanced breast cancer who volunteered for the trials, risking what time they had left on an unproven treatment. Meticulously researched, written with clarity and compassion, Her-2 is masterly reporting on cutting-edge science.

Download or read book Adjuvant Therapy for Breast Cancer written by Monica Castiglione and published by Springer Science & Business Media. This book was released on 2009-07-11 with total page 483 pages. Available in PDF, EPUB and Kindle. Book excerpt: Adjuvant treatment is administered prior to or as follow up to surgical procedures for breast cancer. Proven success in using medical therapies allowing for breast conserving procedures or reducing risk of occurrence. Although there has been much progress towards a cure, including the introduction of new targeted therapies, metastasizing cancer remains highly incurable.

Download or read book Targeted Therapies in Breast Cancer written by Gw Sledge and published by Clinical Pub. This book was released on 2012-06 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new volume updates the reader on selected areas of targeted therapy in breast cancer, with special emphasis on chemoprevention strategies, drug resistance, biomarkers, combination chemotherapy, angiogenesis inhibition and pharmacogenomics in the context of clinical efficacy. This selected review of targeted therapies will guide the reader on effective treatment as part of an integrated programme of patient management.

Download or read book Preoperative Neoadjuvant Chemotherapy written by Joseph Ragaz and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite recent advances in adjuvant therapies of cancer, the regi mens of postoperative adjuvant chemotherapy treatment which are presently available fail to cure the majority of cancer patients. Pre operative (neoadjuvant) chemotherapy represents a new approach in drug scheduling, based on sound theoretical, pharmacokinetic, and experimental principles. The preoperative timing of chemotherapy before definitive sur gery is not a minor change in the therapy of cancer. To be successful, large numbers of practitioners and their patients must participate. Substantial alterations of many aspects of the present management of cancer will have to follow. Therefore, before such therapy can be fully and routinely implemented, results of the novel treatment and its rationale have to be carefully evaluated. In preoperative treatment, other features will likely gain impor tance. For the first time, clinicians have a chance to follow the in vivo response of the tumor exposed to preoperative chemotherapy. The subsequent histological assessment of the tumor sample may likely become an important prognostic guide, permitting more re fined individual approaches to the planning of postoperative adju vant treatment. The value of such a treatment strategy can already be appreciated in the clinical setting, as seen from the therapy of osteosarcoma. Furthermore, preoperative chemotherapy might render previously inoperable tumors operable and hence resectable with a curative intention. The preoperative reduction of tumor bulk may also effectively decrease the need for more radical operations, permitting a more uniform adoption of conservative surgery.

Download or read book Accelerated Partial Breast Irradiation written by David E. Wazer and published by Springer Science & Business Media. This book was released on 2009-08-11 with total page 447 pages. Available in PDF, EPUB and Kindle. Book excerpt: Accelerated partial breast irradiation (APBI) is being rapidly introduced into the clinical management of early breast cancer. APBI, in fact, encompasses a number of different techniques and approaches that include brachytherapy, intraoperative, and external beam techniques. There is currently no single source that describes these techniques and their clinical implementation. This text is a concise handbook designed to assist the clinician in the implementation of APBI. This includes a review of the principles that underlie APBI, a practical and detailed description of each technique for APBI, a review of current clinical results of APBI, and a review of the incidence and management of treatment related complications.

Download or read book The Tumor written by John Grisham and published by Focused Ultrasound Foundation. This book was released on 2015-03 with total page 71 pages. Available in PDF, EPUB and Kindle. Book excerpt: John Grisham says THE TUMOR is the most important book he has ever written. In this short book, he provides readers with a fictional account of how a real, new medical technology could revolutionize the future of medicine by curing with sound. THE TUMOR follows the present day experience of the fictional patient Paul, an otherwise healthy 35-year-old father who is diagnosed with a malignant brain tumor. Grisham takes readers through a detailed account of Paul’s treatment and his family’s experience that doesn’t end as we would hope. Grisham then explores an alternate future, where Paul is diagnosed with the same brain tumor at the same age, but in the year 2025, when a treatment called focused ultrasound is able to extend his life expectancy. Focused ultrasound has the potential to treat not just brain tumors, but many other disorders, including Parkinson’s, Alzheimer’s, hypertension, and prostate, breast and pancreatic cancer. For more information or to order a free hardcopy of the book, please visit The Focused Ultrasound Foundation’s website www.fusfoundation.org. Here you will find a video of Grisham on the TEDx stage with the Foundation’s chairman and a Parkinson’s patient who brings the audience to its feet sharing her incredible story of a focused ultrasound “miracle.” Readers will get a taste of the narrative they expect from Grisham, but this short book will also educate and inspire people to be hopeful about the future of medical innovation.

Download or read book Central Nervous System Metastases written by Manmeet Ahluwalia and published by Springer Nature. This book was released on 2019-11-05 with total page 411 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of brain metastases, from the molecular biology aspects to therapeutic management and perspectives. Due to the increasing incidence of these tumors and the urgent need to effectively control brain metastatic diseases in these patients, new therapeutic strategies have emerged in recent years. The volume discusses all these innovative approaches combined with new surgical techniques (fluorescence, functional mapping, integrated navigation), novel radiation therapy techniques (stereotactic radiosurgery) and new systemic treatment approaches such as targeted- and immunotherapy. These combination strategies represent a new therapeutic model in brain metastatic patients in which each medical practitioner (neurosurgeon, neurologist, medical oncologist, radiation oncologist) plays a pivotal role in defining the optimal treatment in a multidisciplinary approach. Written by recognized experts in the field, this book is a valuable tool for neurosurgeons, neuro-oncologists, neuroradiologists, medical oncologists, radiation oncologists, cognitive therapists, basic scientists and students working in the area of brain tumors.

Download or read book CURRENT Procedures Surgery written by Rebecca Minter and published by McGraw Hill Professional. This book was released on 2010-05-28 with total page 399 pages. Available in PDF, EPUB and Kindle. Book excerpt: Learn to perform more than 50 of the most common surgical procedures with this step-by-step, superbly illustrated guide! CURRENT Procedures Surgery is a unique combination atlas and text that details everything that you must know to perform more than 50 key surgical procedures. It covers the full spectrum of general surgery in an ultra-convenient, at-a-glance format, with more than 400 beautifully rendered illustrations to guide you every step of the way. An easy to follow template for each procedure includes: Indications, Contraindications, Informed Consent, Equipment, Patient Preparation, Patient Positioning, Procedure, Postoperative Care, Potential Complications, Pearls and Tips, References. Features: More than 400 illustrations created specifically for this book along with clear, concise text show you how to perform essential surgical procedures Coverage includes procedures for the breast, gastrointestinal tract, diaphragm, pancreas, liver, thyroid, parathyroid, adrenal, arteries and veins, and more Templated presentation facilitates rapid review Author's pearls and tips included for each procedure A must-have resource for anyone starting their surgical residency

Download or read book Diseases of the Breast written by Jay R. Harris and published by Lippincott Williams & Wilkins. This book was released on 2012-03-28 with total page 3432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Completely revised and updated, and now in full color throughout, the Fourth Edition of this definitive reference is a must for all clinicians who treat breast diseases. Leading experts summarize the current knowledge of breast diseases, including their clinical features, management, underlying biologies, and epidemiologies. In addition to complete coverage of malignant breast diseases, benign diseases are discussed in relation to subsequent breast cancer development. The book reviews all major clinical trials and summarizes the information they provide on early detection and management of breast cancer. Close attention is also given to the increasing importance of molecular biology and genetics in this field. This edition features more than thirty new contributors, fourteen new or completely rewritten chapters, and more clinically oriented chapters. A companion Website will offer the fully searchable text and an image bank. Also included with this edition is the Anatomical Chart Company's Breast Anatomy and Disorders Pocket Guide. This durable, portable folding pocket guide provides a visual and textual overview of breast anatomy, disorders, and breast self-examination. With a write-on, wipe-off laminated surface, this guide is perfect for the on-the-go practitioner to show patients, caregivers, and families.

Download or read book Harrison s Manual of Oncology written by Bruce A. Chabner and published by McGraw Hill Professional. This book was released on 2007-12-02 with total page 648 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lange Q&A: Mammography Examination is a comprehensive study guide for the ARRT’s Mammography Examination. The book summarizes the mammography curriculum in a clear and concise format and includes review Q&A plus two complete practice exams. With this book, radiographic technicians get the practice they need to pass the registry examination with flying colors.

Download or read book Breast Cancer written by Adnan Aydiner and published by Springer. This book was released on 2018-11-08 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a practical guide to the management of patients with breast malignancies. It serves as a quick reference book that gives the most up-to-date routine practical management strategies of breast cancer. Written and edited by leading experts, this handbook focuses on the application of conventional and novel treatment strategies to the care of patients with malignant breast disease and all stages of breast cancer. The chapters provide evidence-based treatment strategies for all patient subsets. Surgical, radiation, and medical treatment options are all discussed for each stage of breast cancer. It also includes the definitions of statistical terminologies and their usage in clinical practice and research. This is a comprehensive yet concise resource for residents, fellows, and early-career practitioners.

Download or read book WHO Classification of Tumours of the Breast written by Sunil R. Lakhani and published by World Health Organization. This book was released on 2012 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: WHO Classification of Tumours of the Breast is the fourth volume of the WHO series on histological and genetic typing of human tumours. This authoritative, concise reference book provides an international standard for oncologists and pathologists and will serve as an indispensable guide for use in the design of studies monitoring response to therapy and clinical outcome. Diagnostic criteria, pathological features, and associated genetic alterations are described in a strictly disease-oriented manner. Sections on all recognized neoplasms and their variants include new ICD-O codes, epidemiology, clinical features, macroscopy, pathology, genetics, and prognosis and predictive factors. The book, prepared by 90 authors from 24 countries, contains more than 340 colour photographs, tables and figures, and more than 1600 references.

Download or read book Sabiston Textbook of Surgery written by Courtney M. Townsend and published by W B Saunders Company. This book was released on 2001 with total page 1750 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 16th Edition of this classic text provides surgeons with the most comprehensive information available in this field. This exhaustive revision includes more than 1,500 illustrations and 1,800 of the most recent references available in surgery. Included are: advances in cardiothoracic surgery, neurosurgery, plastic and maxillofacial surgery, pediatric surgery, hand surgery, orthopedics, gynecology, and urology, as well as the historical and developmental aspects of surgical practice and the anatomical, pathological, physiological, biochemical and molecular basis of several disorders.

Download or read book Treatment of Malignant Breast Tumors written by Pierre Denoix and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 169 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the chief concerns of the medical staff of the Institut Gustave-Roussy is to find the right indications for treating every cancer site, and particularly cancer of the breast. The best treatment is the one which offers the patient the best chance of recovery, yet is at the same time the simplest and least mutilating [36]. It is our policy at the Institut, rather than to lay down a series of therapeutic measures which are applied systematically to all patients, to be selective, that is, to determine the best treatment for each individual patient. We make extensive use of prognostic factors, not merely for retrospective assessment when the treatment is completed, but very early on-during treatment or even before it is begun; thus, the treatment may be changed as a result, or simplified from the outset, when it is thought the outcome will be equally satisfactory. Our appreciation of the prognostic value of this or that clinical or biological factor is still far from complete, and we are continuing our studies in this direction.

Download or read book Management of Benign and Malignant Breast Disease An Issue of Obstetrics and Gynecology Clinics E Book written by Patrice M Weiss and published by Elsevier Health Sciences. This book was released on 2022-02-24 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this issue of Obstetrics and Gynecology Clinics, guest editors Patrice Weiss and Jessica F. Partin bring their considerable expertise to the topic of Management of Benign and Malignant Breast Disease. - Provides in-depth reviews on the latest in Management of Benign and Malignant Breast Disease. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field; Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews.