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Book Lung Cancer

    Book Details:
  • Author : David J. Stewart
  • Publisher : Springer Science & Business Media
  • Release : 2010-03-10
  • ISBN : 160761524X
  • Pages : 544 pages

Download or read book Lung Cancer written by David J. Stewart and published by Springer Science & Business Media. This book was released on 2010-03-10 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: Defining the Lung Cancer Problem 1 Lung cancer is the leading cause of cancer death in the world. It kills almost as many Americans as cancers of the breast, prostate, colon, rectum, pancreas, and 2 kidney combined, and accounts for 28.6% of all US cancer deaths. With an increase in the 5-year relative survival rate from 13% to only 16% in the more than 2 30 years from 1974 to the present, it will take us another 840 years to eradicate lung cancer deaths if we do not improve the current rate of progress. As discussed in this text, lung cancer prevention has received substantial att- tion. The decrease in smoking in recent decades has helped, but smoking is not the only problem. Lung cancer in people who have never smoked is currently the 5th 3 leading cause of cancer death in the United States. Several factors contribute to the lethality of lung cancer, including the rapidity of tumor growth, advanced stage at diagnosis (due to nonspecificity of early sy- toms and the uncertain efficacy of screening), early development of metastases, and resistance to therapy. Several chapters in this book discuss new molecular targets that may be potentially exploitable in the future, as well as discussing our track record to date in exploiting them.

Book Non small Cell Lung Cancer Treatment

Download or read book Non small Cell Lung Cancer Treatment written by Christian Manegold and published by . This book was released on 2010 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Non Small Cell Lung Cancer  Prevention  Management and Emerging Therapies

Download or read book Non Small Cell Lung Cancer Prevention Management and Emerging Therapies written by Rex White and published by American Medical Publishers. This book was released on 2023-09-26 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Non-small cell lung cancer refers to a disease in which the cancer cells are formed in tissues of the lung. There are three common types of non-small cell lung cancer, namely, adenocarcinoma, squamous cell carcinoma and large cell carcinoma. Smoking cigars, pipes or cigarettes is the major cause of this disease. Radiation therapy, air pollution and pulmonary fibrosis are some other causes of non-small cell lung cancer. Some common symptoms of non-small cell lung cancer are chest pain, appetite loss, unexplained weight loss, tiredness, and swelling of face or the veins in the neck. Patients can be examined by certain diagnostic tests, like chest X-rays, blood or urine tests, sputum cytology, bronchoscopy, etc. Surgery is the major treatment for non-small cell lung cancer. Some other treatments include radiofrequency ablation, chemotherapy, and targeted drug therapy. This book provides comprehensive insights into the prevention, management and emerging therapies for non-small cell lung cancer. It presents researches and studies performed by experts across the globe. This book will prove to be immensely beneficial to students and researchers studying this medical condition.

Book Treatment for Non Small Cell Lung Cancer in Distinct Patient Populations

Download or read book Treatment for Non Small Cell Lung Cancer in Distinct Patient Populations written by Junji Uchino and published by Frontiers Media SA. This book was released on 2022-02-24 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Lung Cancer

    Book Details:
  • Author : Karen L. Reckamp
  • Publisher : Springer
  • Release : 2016-08-17
  • ISBN : 3319403893
  • Pages : 322 pages

Download or read book Lung Cancer written by Karen L. Reckamp and published by Springer. This book was released on 2016-08-17 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the molecular mechanisms of lung cancer development and progression that determine therapeutic interventions in the era of genomics, when the rapid evolution in lung cancer diagnosis and treatment necessitates critical review of new results to integrate advances into practice. The text opens with background and emerging information regarding the molecular biology of lung cancer pathogenesis. Updated results regarding lung cancer prevention and screening are discussed, followed by chapters on diagnostic techniques and pathological evaluation. This leads on to a detailed presentation of treatment modalities, from surgery and radiation therapy to standard chemotherapy and targeted agents. The coverage includes resistance to therapy and the emergence of immunotherapy for lung cancer; in addition, the current evidence in respect of small cell lung cancer is summarized. The book presents insights from experts across disciplines to emphasize the importance of collaborative care. Advances in our understanding of issues in geriatric oncology and palliative care complete the comprehensive discussion of lung cancer.

Book Principles and Practice of Lung Cancer

Download or read book Principles and Practice of Lung Cancer written by Harvey I. Pass and published by Lippincott Williams & Wilkins. This book was released on 2012-02-13 with total page 1056 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thoroughly revised and updated, this Fourth Edition is the most comprehensive, current reference on lung cancer, with contributions from the world's foremost surgeons, radiation oncologists, medical oncologists, pulmonologists, and basic scientists. Coverage includes complete information on combined modality treatments for small cell and non-small cell lung cancer and on complications of treatment and management of metastases. Emphasis is also given to early detection, screening, prevention, and new imaging techniques. This edition has expanded thoracic oncology chapters including thymus, mesothelioma, and mediastinal tumors, more detailed discussion of targeted agents, and state-of-the-art information on newer techniques in radiotherapy. Other highlights include more international contributors and greater discussion of changes in lung cancer management in each region of the world. A new editor, Giorgio Scagliotti, MD from the University of Turin, has coordinated the accounts of European activities. A companion website includes the full text online and an image bank.

Book Updates in Advances in Lung Cancer

Download or read book Updates in Advances in Lung Cancer written by Joan H. Schiller and published by Karger Medical and Scientific Publishers. This book was released on 1997-01-01 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lung cancer remains a major cause of cancer deaths throughout the world. It is an extremely lethal neoplasm: 80-90% of patients who develop lung cancer will die of their disease. The purpose of this book is to update cancer specialists, pulmonary physicians, thoracic surgeons and general practitioners about the many recent advances in the treatment, prevention and biology of lung cancer. Despite the overall poor prognosis for patients, a number of new chemotherapeutic drugs and regimens have been developed which result in a clinically meaningful improvement in survival for patients with nonsmall cell lung carcinoma. Four chapters in this book are devoted to reviewing these new drugs and drug combinations (paclitaxel, docetaxel, vinorelbine, gemcitabine, topoisomerase inhibitors). Advances in the management of locally advanced nonsmall cell and small cell lung cancer are considered, including combined-modality treatments using chemotherapy, surgery, and radiation therapy. Results of recent trials involving chemoprevention agents are also reported. Finally, the latest progress in understanding the molecular biology of this disease, and how it might impact on the clinical management of lung cancer patients, is discussed.

Book Molecular Pathology of Lung Cancer

Download or read book Molecular Pathology of Lung Cancer written by Philip T. Cagle and published by Springer Science & Business Media. This book was released on 2012-06-14 with total page 217 pages. Available in PDF, EPUB and Kindle. Book excerpt: As with other books in the Molecular Pathology Library Series, Molecular Pathology of Lung Cancer bridges the gap between the molecular specialist and the clinical practitioner, including the surgical pathologist who now has a key role in decisions regarding molecular targeted therapy for lung cancer. Molecular Pathology of Lung Cancer provides the latest information and current insights into the molecular basis for lung cancer, including precursor and preinvasive lesions, molecular diagnosis, molecular targeted therapy, molecular prognosis, molecular radiology and related fields for lung cancer generally and for the specific cell types. As many fundamental concepts about lung cancer have undergone revision in only the past few years, this book will likely be the first to comprehensively cover the new molecular pathology of lung cancer. It provides a foundation in this field for pathologists, medical oncologists, radiation oncologists, thoracic surgeons, thoracic radiologists and their trainees, physician assistants, and nursing staff.

Book Lung Cancer

    Book Details:
  • Author : Jack A. Roth
  • Publisher : John Wiley & Sons
  • Release : 2014-03-26
  • ISBN : 1118468775
  • Pages : 1077 pages

Download or read book Lung Cancer written by Jack A. Roth and published by John Wiley & Sons. This book was released on 2014-03-26 with total page 1077 pages. Available in PDF, EPUB and Kindle. Book excerpt: The best and most concise single source for state-of-the-art diagnosis and treatment of lung cancer –newly revised, updated, and expanded. Lung cancer has long been the number-one cause of death from cancer every year and the third most frequently diagnosed after breast and prostate cancers. In 2010, about 15% of all cancer diagnoses and 30% of all cancer deaths were due to lung cancer. Needless to say, there is a great need for more rapid advancements in diagnosis and treatment of this devastating disease. Here is the comprehensively revised, updated, and expanded edition of the well-established, evidence-based reference book that deals with the most recent advances in lung cancer prevention, screening, diagnosis, research, and treatment for the clinician. Edited and authored by leading authorities in the field, this Fourth Edition of the highly regarded Lung Cancer is better than ever –featuring nine new chapters along with seven re-formatted ones that are nearly brand new in content and approach. It covers Smoking Prevention and Cessation; Molecular Profiling; Somatic Genome Alterations in Human Lung Cancers; Management of Multi-Focal Bronchioloalveolar Carcinoma (BAC); Primary Tracheal Tumors; Predictive Tumor Biomarkers for EGFR Inhibitors; Non-Small Cell and Small-Cell Lung Carcinoma; and more. This Fourth Edition of Lung Cancer: Provides the very latest research in the identification of biomarkers to predict a high risk for developing lung cancer – vital for implementing screening, diagnosis, and prevention strategies Presents the newest lung cancer staging system, as well as updated and cutting-edge surgical and radiation therapy techniques that make local tumor control more effective and less invasive while sparing normal tissues Discusses combined modality therapy and new chemotherapeutic agents which are yielding higher response rates and improved survival when used in the adjuvant setting or concurrent with highly sophisticated radiation or proton treatment Offers novel and emergent approaches to preventative, diagnostic, and therapeutic modalities with an emphasis on the best evidence available from the latest studies and clinical trials With almost half of the revised and updated content being brand new, Lung Cancer, Fourth Edition, is an important and vital resource for all medical professionals and students involved in the care and treatment of those struck with this catastrophic illness.

Book Epidemiology of Lung Cancer

Download or read book Epidemiology of Lung Cancer written by Jonathan M. Samet and published by CRC Press. This book was released on 1994-03-08 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing a historical perspective on the etiology of lung cancer, this comprehensive reference presents an in-depth analysis of the epidemiology of cancer of the lung-describing the current understanding of risk factors and the use of epidemiological data to design programs for the control of this leading cause of death worldwide.

Book Fast Facts  Non Small Cell Lung Cancer

Download or read book Fast Facts Non Small Cell Lung Cancer written by Mary O'Brien and published by Karger Medical and Scientific Publishers. This book was released on 2022-02-28 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite an overall decrease in tobacco use, lung cancer (80–85% of which is non-small-cell lung cancer [NSCLC]) is still the leading cause of cancer death in both men and women worldwide. Annual low-dose CT screening of high-risk individuals has the potential to detect early-stage tumors, which can usually be successfully treated with a combination of surgery, radiotherapy and chemotherapy and, in some cases, targeted therapy. However, most patients with NSCLC still present with advanced or metastatic disease. For these patients, initial therapy is guided by the tumor’s molecular characteristics and patient’s performance status. Targeted therapies have significantly improved clinical outcomes and, for some patients with no targetable genetic alterations, immunotherapy has demonstrated significant overall survival benefit. This insightful guide is designed to bring you up to speed with the latest developments and is important reading for all health professionals and medical trainees working in this fast-moving field. Table of Contents: • Prevention and screening • Diagnosis and staging • Surgery • Radiotherapy • Systemic therapy in non-metastatic NSCLC • Systemic therapy in advanced-stage/metastatic disease without a molecular driver • Personalized treatment in advanced NSCLC • Oligometastatic disease and brain metastases

Book Histological Typing of Lung and Pleural Tumours

Download or read book Histological Typing of Lung and Pleural Tumours written by W.D. Travis and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 139 pages. Available in PDF, EPUB and Kindle. Book excerpt: with contributions by Pathologists from 14 Countries

Book Lung Cancer  Standards of Care

Download or read book Lung Cancer Standards of Care written by Goetz Kloecker and published by McGraw Hill Professional. This book was released on 2021-01-08 with total page 509 pages. Available in PDF, EPUB and Kindle. Book excerpt: An essential guide to the treatment and management of lung cancer Lung cancer remains the leading cause of cancer deaths worldwide, attributed mostly to environmental and behavioral factors. However, a diagnosis of lung cancer no longer means inevitable death. The new standards of care and a greater understanding of the etiology and biology of the disease has led to breakthroughs in patient survival rates that were not seen in the past. Standards of Care: Lung Cancer provides a solid foundation in the new principles approaching this disease. Presented in an accessible, quick-to-digest format, and written by leading experts in a variety of medical fields, this authoritative guide covers all the new procedures and treatment options and the latest advances in diagnosis and treatment, including immunotherapy and oncogene inhibition, and more. This is an essential resource for both practitioners and students studying for the boards or certification. Features Covers the most current treatments Continuous online updates on guidelines, new therapies, and studies Includes checklists, case studies, learning objectives, and clinical pearls Bibliography with listings of studies and trials Serves as an ideal resource for practice and board review

Book Targeted Therapies for Lung Cancer

Download or read book Targeted Therapies for Lung Cancer written by Ravi Salgia and published by Springer. This book was released on 2019-06-26 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contextualizes translational research and provides an up to date progress report on therapies that are currently being targeted in lung cancer. It is now well established that there is tremendous heterogeneity among cancer cells both at the inter- and intra-tumoral level. Further, a growing body of work highlights the importance of targeted therapies and personalized medicine in treating cancer patients. In contrast to conventional therapies that are typically administered to the average patient regardless of the patient’s genotype, targeted therapies are tailored to patients with specific traits. Nonetheless, such genetic changes can be disease-specific and/or target specific; thus, the book addresses these issues manifested in the somatically acquired genetic changes of the targeted gene. Each chapter is written by a leading medical oncologist who specializes in thoracic oncology and is devoted to a particular target in a specific indication. Contributors provide an in-depth review of the literature covering the mechanisms underlying signaling, potential cross talk between the target and downstream signaling, and potential emergence of drug resistance.

Book Central Nervous System Metastases in Lung Cancer Patients  From Prevention to Diagnosis and Treatment

Download or read book Central Nervous System Metastases in Lung Cancer Patients From Prevention to Diagnosis and Treatment written by Lizza E.L Hendriks and published by Frontiers Media SA. This book was released on 2019-01-21 with total page 94 pages. Available in PDF, EPUB and Kindle. Book excerpt: Approximately 40% of lung cancer patients will develop central nervous system (CNS) metastases during the course of their disease. Most of these are brain metastases, but up to 10% will develop leptomeningeal metastases. Known risk factors for CNS metastases development are small cell lung cancer (SCLC), adenocarcinoma histology, epidermal growth factor receptor (EGFR) mutant or anaplastic lymphoma kinase (ALK) rearranged lung cancer, advanced nodal status, tumor stage and younger age. CNS metastases can have a negative impact on quality of life (QoL) and overall survival (OS). The proportion of lung cancer patients diagnosed with CNS metastases has increased over the years due to increased use of brain imaging as part of initial cancer staging, advances in imaging techniques and better systemic disease control. Post contrast gadolinium enhanced magnetic resonance imaging (gd-MRI) is preferred, however when this is contra-indicated a contrast enhanced computed tomography (CE-CT) is mentioned as an alternative option. When CNS metastases are diagnosed, local treatment options consist of radiotherapy (stereotactic or whole brain) and surgery. Local treatment can be complicated by symptomatic radiation necrosis for which no high level evidence based treatment exists. Moreover, differential diagnosis with metastasis progression is difficult. Systemic treatment options have expanded over the last years. Until recently, chemotherapy was the only treatment option with a poor penetration in the CNS. Angiogenesis inhibitors are promising in the treatment of primary CNS tumors as well as radiation necrosis but clinical trials of anti-angiogenic agents in NSCLC have largely excluded patients with CNS metastases. Furthermore, research has also focused on methods to prevent development of CNS disease, for example with prophylactic cranial irradiation. Recently, checkpoint inhibitors have become available for NSCLC patients, and tyrosine kinase inhibitors (TKIs) have improved prognosis significantly in those with a druggable driver mutation. Newer TKIs are often designed to have better CNS penetration compared to first-generation TKIs. Despite advances in treatment options CNS metastases remain a problem in lung cancer and cause morbidity and mortality. This Research Topic provides an extensive resource of articles describing advances in CNS metastases management in lung cancer patients, from prevention to diagnosis and treatment.

Book Lung Cancer

    Book Details:
  • Author : Frank V. Fossella
  • Publisher : Springer Science & Business Media
  • Release : 2003
  • ISBN : 0387955070
  • Pages : 327 pages

Download or read book Lung Cancer written by Frank V. Fossella and published by Springer Science & Business Media. This book was released on 2003 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lung cancer remains the leading cause of cancer-related death in men, and in women, it has surpassed even breast cancer. According to the American Cancer Society, in 2001, there will be about 169,500 new cases of lung cancer in the United States: 90,700 among men and 78,800 among women. Lung Cancer is the second installment in the M. D. Anderson Cancer Care Series, featuring the current standard approach to lung cancer care from the experts at M. D. Anderson Cancer Center. Designed for the practicing oncologist, this clinical guidebook allows for quick, authoritative access to the latest and best multimodality therapies. Topics covered in this volume include the clinical examination of patients with suspected lung cancer, thoracic imaging techniques for non-small cell and small cell lung cancer, pathology of lung cancer, treatment and management of non-small and small-cell lung cancer, including the role of guidelines and clinical pathways, molecular events in lung cancer and implications for prevention and therapy, palliation, and much more. Each of the 15 chapters ends with an up-to-date list of suggested readings, as well as "key practice points" highlighting the most important principles and practices of each chapter for at-a-glance reference. Over 50 illustrations and 40 tables round out the text. This thorough, practical volume is the essential clinical guide for oncologists, surgeons, and all physicians involved in the care of patients with lung cancer.