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Book Homologous Bone Marrow Transplantation in Dogs Receiving X Radiation Plus Urethane Or 6 mercaptopurine

Download or read book Homologous Bone Marrow Transplantation in Dogs Receiving X Radiation Plus Urethane Or 6 mercaptopurine written by L. J. Cole and published by . This book was released on 1962 with total page 44 pages. Available in PDF, EPUB and Kindle. Book excerpt: Experience has now been accumulated with homologous marrow transplantation in 13 mongrel dogs (Group 1) treated with 6-mercaptopurine (6-MP) or urethane prior to X irradiation (900 r, delivered at a dose rate of 15 r/minute). The marrow dose was 7 to 11 billion cells, given on the day following irradiation; urethane (175 or 350 mg/kg) and 6-MP (12.5 or 25 mg/kg) were administered at 3 or 4 daily intervals during the week prior to irradiation. Mean survival time (MST) in Group 1 was 23 days, with a maximum of 63 days. MST in a group of dogs (Group 2) given homologous marrow after 900 r, but not treated with the chemicals, was 10 days. The marrow showed active hematopoiesis and moderate to good cellularity in most of the Group 1 animals, although megakaryocyte activity was deficient in some. Pneumonia and pulmonary edema were found in many of the dogs, at autopsy. The use of these anti-metabolites permits the successful transplantation of homologous marrow in dogs at a dose of X radiation (900 r) which, by itself, is insufficient. Urethane and 6-mercaptopurine are additive to X radiation with respect to suppressing the homograft reaction in dogs, as well as in mice. (Author).

Book Contemporary Bone Marrow Transplantation

Download or read book Contemporary Bone Marrow Transplantation written by Mammen Chandy and published by Springer. This book was released on 2021-03-25 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bone Marrow transplantation or Hematopoietic stem cell transplantation is a life saving procedure in a number of diseases,hematological and non hematological, which fail alternative medical management or have no other treatment options. It has transformed the lives of thousands of patients and their families around the world battling with fatal or debilitating diseases.There are many unique aspects of bone marrow transplantation which makes it very different from solid organ transplants. There is an enormous amount of research going on in this field both at clinical and basic science levels.With the rapidly changing world and field of transplantation, there is a need for an authoritative and up to date resource for transplant professionals. This book titled Contemporary Bone Marrow Transplantation aims to be a reference text comprehensively covering various facets of hematopoietic stem cell transplants with latest insights about the technique and basic science behind it . The book is the product of collective effort of transplant professionals round the world, and will reflect their experience as well as the current standard of care practices in Stem cell transplantation.The book will be divided into different sections focusing on the basic science of bone marrow transplant, the technical aspects of the procedure itself and the supportive care of transplant patients.There will also be a section each on epidemiology, upcoming trends and also case studies , which will discuss real case scenarios from the experience of the authors, to illustrate the practical challenges in managing bone marrow transplant recipients.

Book Withrow and MacEwen s Small Animal Clinical Oncology

Download or read book Withrow and MacEwen s Small Animal Clinical Oncology written by Stephen J. Withrow and published by Elsevier Health Sciences. This book was released on 2012-11-13 with total page 775 pages. Available in PDF, EPUB and Kindle. Book excerpt: With a unique focus on the most effective interventional techniques, Withrow & MacEwen's Small Animal Clinical Oncology, 5th Edition tells the full story of cancer in dogs and cats - what it is, how to diagnose it, and how to treat many of the most common cancers encountered in clinical practice. Nearly 500 color photographs, diagrams, x-rays, and gross views depict the clinical manifestations of various cancers. This edition covers the latest advances in clinical oncology, including chemotherapy, surgical oncology, and diagnostic techniques. With contributions from 65 veterinary oncology experts, this authoritative reference is a must-have for current, evidence-based therapeutic strategies on canine and feline oncology. "I really love this book. If you are interested in veterinary oncology, have a flick through this book online or at a conference when you get the chance. I hope that you agree with me that this is the definitive oncology reference source for the early 21st century and that you feel compelled to buy it. Your patients will thank you for it." Reviewed by: Gerry Polton MA VetMB MSc(Clin Onc) DipECVIM-CA(Onc) MRCVS, UK Date: July 2014 Cutting-edge information on the complications of cancer, pain management, and the latest treatment modalities prepares you to diagnose and treat pets with cancer rather than refer cases to a specialist. A consistent format for chapters on body system tumors includes coverage of incidence and risk factors, pathology, natural behavior of tumors, history and clinical signs, diagnostic techniques and workup, treatment options, and prognosis for specific malignancies. A systems approach to the diagnosis and management of cancer facilitates access to information about the many malignancies affecting small animal patients. Nearly 500 color images provide accurate depictions of specific diseases and procedures. Helpful drug formularies provide quick access to information on indications, toxicities, and recommended dosages for chemotherapeutic and analgesic drugs used in cancer treatment. Expert contributors provide in-depth coverage of the most current information in his or her respective specialty in veterinary oncology. Chemotherapy protocols are included when case studies prove clinical efficacy. Discussion of compassion and supportive care for the management of pain, nutritional needs, and grief includes methods for handling the pet's pain and nutritional complications as well as the pet owner's grief when treatment is not successful. Thoroughly UPDATED chapters cover the most recent changes in the clinical management of melanoma, mast cell tumors, tumors of the skeletal system, tumors of the endocrine system, tumors of the mammary gland, urinary cancers, nervous system cancers, lymphoma, and histiocytic diseases. NEW Clinical Trials and Developmental Therapeutics chapter discusses the various phases of clinical trials as well as current challenges and opportunities in oncology drug development. NEW! A focus on the best recommended treatment options highlights therapeutic strategies that have been vetted by veterinary oncology experts. NEW co-author Dr. Rodney L. Page adds his valuable perspective, expertise, and research experience.

Book AECD

    Book Details:
  • Author :
  • Publisher :
  • Release : 1966
  • ISBN :
  • Pages : 200 pages

Download or read book AECD written by and published by . This book was released on 1966 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Index catalogue of the Library

Download or read book Index catalogue of the Library written by Library of the Surgeon-General's Office (U.S.) and published by . This book was released on 1961 with total page 908 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Technical Information Pilot

Download or read book Technical Information Pilot written by and published by . This book was released on 1949 with total page 694 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Clinical Radiation Oncology

    Book Details:
  • Author : Leonard L. Gunderson, MD, MS, FASTRO
  • Publisher : Elsevier Health Sciences
  • Release : 2015-08-26
  • ISBN : 0323240984
  • Pages : 2253 pages

Download or read book Clinical Radiation Oncology written by Leonard L. Gunderson, MD, MS, FASTRO and published by Elsevier Health Sciences. This book was released on 2015-08-26 with total page 2253 pages. Available in PDF, EPUB and Kindle. Book excerpt: Perfect for radiation oncology physicians and residents needing a multidisciplinary, treatment-focused resource, this updated edition continues to provide the latest knowledge in this consistently growing field. Not only will you broaden your understanding of the basic biology of disease processes, you'll also access updated treatment algorithms, information on techniques, and state-of-the-art modalities. The consistent and concise format provides just the right amount of information, making Clinical Radiation Oncology a welcome resource for use by the entire radiation oncology team. Content is templated and divided into three sections -- Scientific Foundations of Radiation Oncology, Techniques and Modalities, and Disease Sites - for quick access to information. Disease Sites chapters summarize the most important issues on the opening page and include a full-color format, liberal use of tables and figures, a closing section with a discussion of controversies and problems, and a treatment algorithm that reflects the treatment approach of the authors. Chapters have been edited for scientific accuracy, organization, format, and adequacy of outcome data (such as disease control, survival, and treatment tolerance). Allows you to examine the therapeutic management of specific disease sites based on single-modality and combined-modality approaches. Features an emphasis on providing workup and treatment algorithms for each major disease process, as well as the coverage of molecular biology and its relevance to individual diseases. Two new chapters provide an increased emphasis on stereotactic radiosurgery (SRS) and stereotactic body irradiation (SBRT). New Associate Editor, Dr. Andrea Ng, offers her unique perspectives to the Lymphoma and Hematologic Malignancies section. Key Points are summarized at the beginning of each disease-site chapter, mirroring the template headings and highlighting essential information and outcomes. Treatment algorithms and techniques, together with discussions of controversies and problems, reflect the treatment approaches employed by the authors. Disease Site Overviews allow each section editor to give a unique perspective on important issues, while online updates to Disease Site chapters ensure your knowledge is current. Disease Site chapters feature updated information on disease management and outcomes. Four videos accessible on Expert Consult include Intraoperative Irradiation, Prostate Brachytherapy, Penile Brachytherapy, and Ocular Melanoma. Thirty all-new anatomy drawings increase your visual understanding. Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.

Book Navy Research Task Summary

    Book Details:
  • Author : United States. Office of Naval Research
  • Publisher :
  • Release :
  • ISBN :
  • Pages : 368 pages

Download or read book Navy Research Task Summary written by United States. Office of Naval Research and published by . This book was released on with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Navy Research Task Summary  1961

Download or read book Navy Research Task Summary 1961 written by United States. Office of Naval Research and published by . This book was released on 1962 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Cumulated Index Medicus

Download or read book Cumulated Index Medicus written by and published by . This book was released on 1983 with total page 1052 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Radiation Oncology E Book

    Book Details:
  • Author : James D. Cox
  • Publisher : Elsevier Health Sciences
  • Release : 2009-10-29
  • ISBN : 0323076602
  • Pages : 1085 pages

Download or read book Radiation Oncology E Book written by James D. Cox and published by Elsevier Health Sciences. This book was released on 2009-10-29 with total page 1085 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radiation Oncology: Rationale, Technique, Results, by James D. Cox, MD and K. Kian Ang, MD, PhD, provides you with authoritative guidance on the latest methods for using radiotherapy to treat patients with cancer. Progressing from fundamental principles through specific treatment strategies for the cancers of each organ system, it also addresses the effects of radiation on normal structures and the avoidance of complications. This 9th edition covers the most recent indications and techniques in the field, including new developments in proton therapy and intensity-modulated radiotherapy (IMRT). It also features, for the first time, full-color images throughout the text to match those that you see in practice, and uses new color-coded treatment plans to make targets, structures, and doses easier to read at a glance. Evidence from randomized clinical trials is included whenever possible to validate clinical recommendations. The state-of-the-art coverage inside this trusted resource equips you to target cancer as effectively as possible while minimizing harm to healthy tissue. Stands apart as the only book in the field to cover the conceptual framework for the use of radiotherapy by describing the most effective techniques for treatment planning and delivery and presenting the results of each type of therapy. Emphasizes clinical uses of radiation therapy, providing pertinent, easy-to-understand information on state-of-the-art treatments. Includes information useful for non-radiotherapists, making it "recommended reading" for other oncology specialists. Offers a practical, uniform chapter structure to expedite reference. Guides you through the use of the newest radiation oncology techniques, including principles of proton therapy and new developments in intensity-modulated radiotherapy (IMRT). Incorporates evidence from randomized clinical trials whenever possible to validate clinical recommendations. Presents full-color images throughout to match the images that you see in practice. Extensive use of "combination" imaging presents a complete picture of how to more precisely locate and target the radiotherapy field.

Book AECD

    Book Details:
  • Author : U.S. Atomic Energy Commission
  • Publisher :
  • Release :
  • ISBN :
  • Pages : 636 pages

Download or read book AECD written by U.S. Atomic Energy Commission and published by . This book was released on with total page 636 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Response of Different Species to Total Body Irradiation

Download or read book Response of Different Species to Total Body Irradiation written by J.J. Broerse and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: J.J. Broerse, Radiobiological Institute TNO, Rijswijk, The Netherlands, and T .J. MacVittie, Armed Forces Radiobiology Research Institute, Bethesda, MD, USA. During the past decade, relatively few new studies have been initiated on the response of different species to high-dose, total-body irradia tion. For information on the LDSO/30d (the dose which produces 50 percent lethality within 30 days), one is generally referred to the older literature (e. g., Bond, Fliedner and Archambeau, 1965). Compari son of experimental data reveals considerable variations in LDSD values even after total-body irradiation with conventional X rays, ranging from 4 to 6 Gy in the monkey, 7.1 to 9 Gy in the rat and from 6.4 to 9 Gy in the mouse (see also Hall, 1978). Part of the discrepancy in the LDso values can possibly be attributed to inadequacies in the dosimetry procedures and exposure arrangements employed. As far as clinical experience is concerned, there is now an appreciable amount of information available about the effect of total body irradiation as a conditioning treatment for bone marrow transplan tation in patients suffering from leukaemia or aplastic anaemia. The results from different centres, including the incidence of complications such as radiation pneumonitis, are considerably different. This can part I y be connected with the application of different radiation sched ules: large single dose versus fractionated or protracted irradiation.

Book Current Controversies in Bone Marrow Transplantation

Download or read book Current Controversies in Bone Marrow Transplantation written by Brian J. Bolwell and published by Springer Science & Business Media. This book was released on 1999-12-02 with total page 317 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leading transplant physicians critically review and interpret twenty-one key clinical challenges in bone marrow/hematopoietic cell transplantation, and offer their best personal recommendations for treatment. Topics range from transplant strategies to complications of bone marrow transplantation, including a discussion of the indications, benefits, and the risks for a variety of leukemias, lymphomas, and solid tumors. The authors debate such contentious issues as the appropriateness of transplants in older patients, how many stem cells are sufficient for engraftment, and the pros and cons of umbilical cord blood transplantation. Up-to-date and clinically focused, Current Controversies in Bone Marrow Transplantation offers clinical oncologists, hematology/oncology fellows in training, and residents in internal medicine today's best ready reference and management guide for all their critical oncologic problems arising from the use of bone marrow/stem cell transplantation.

Book Leibel and Phillips Textbook of Radiation Oncology   E Book

Download or read book Leibel and Phillips Textbook of Radiation Oncology E Book written by Richard Hoppe and published by Elsevier Health Sciences. This book was released on 2010-09-09 with total page 1666 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stay on top of the latest scientific and therapeutic advances with the new edition of Leibel and Phillips Textbook of Radiation Oncology. Dr. Theodore L. Phillips, in collaboration with two new authors, Drs. Richard Hoppe and Mack Roach, offers a multidisciplinary look at the presentation of uniform treatment philosophies for cancer patients emphasizing the "treat for cure" philosophy. You can also explore the implementation of new imaging techniques to locate and treat tumors, new molecularly targeted therapies, and new types of treatment delivery. Supplement your reading with online access to the complete contents of the book, a downloadable image library, and more at expertconsult.com. Gather step-by-step techniques for assessing and implementing radiotherapeutic options with this comprehensive, full-color, clinically oriented text. Review the basic principles behind the selection and application of radiation as a treatment modality, including radiobiology, radiation physics, immobilization and simulation, high dose rate, and more. Use new imaging techniques to anatomically locate tumors before and during treatment. Apply multidisciplinary treatments with advice from experts in medical, surgical, and radiation oncology. Explore new treatment options such as proton therapy, which can facilitate precise tumor-targeting and reduce damage to healthy tissue and organs. Stay on the edge of technology with new chapters on IGRT, DNA damage and repair, and molecularly targeted therapies.