Download or read book Translational Approaches to Autism Spectrum Disorder written by Maria de los Angeles Robinson-Agramonte and published by Springer. This book was released on 2015-06-10 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses and synthesizes recent basic, translational, and clinical research with the goal of understanding the mechanisms behind autism spectrum disorder (ASD) and how they lead to altered brain function and behavior. Bringing clarity to these mechanisms will lead to more effective therapies for the various heterogeneous pathologies that comprise ASD. Currently there are few, if any, proven therapies for the majority of the disorders. Among the topic addressed are neural plasticity, neuroimmunology, neuroinflammation, neuroimaging, and appropriate animal and genetic models.
Download or read book Neurochemistry in Autism Spectrum Disorder written by Alice Marie Sybille Durieux and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Translational and Clinical Research in Autism Spectrum Disorders written by Paul Spencer and published by American Medical Publishers. This book was released on 2023-09-26 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Autism spectrum disorder (ASD) is a neurodevelopmental disorder that affects how a person perceives and interacts with others, leading to problems in social interaction and communication. Limited and repetitive patterns of conduct are also part of the disorder. While autism is a lifelong disease, the extent to which these challenges limit a person's capacity to function varies from person to person. The term 'spectrum disorders' signifies the wide variety of symptoms and severity associated with autism. Genetic factors are primarily the reason for the disorder's occurrence. ASD appears early in childhood and is related to social, scholastic, and occupational challenges. Autism signs appear as early as the first year of life. Some of the complications linked with the disease include difficulties in school and successful learning, work issues, inability to live independently, social isolation, and family stress. This book is a collection of translational and clinical researches on autism. The readers would gain knowledge that would broaden their perspective about autism spectrum disorders.
Download or read book Behavior Analysis written by Henry S. Roane and published by Guilford Publications. This book was released on 2024-01-26 with total page 594 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Throughout this text, many of the research paradigms and methodologies across experimental analysis of behavior (EAB) and applied behavior analysis (ABA) are presented within the "bench-to-bedside" approach of translational research described by the National Institutes of Health. The first few chapters of the text introduce underlying core tenets of behaviorism as well as core characteristics and methods that define the field of behavior analysis. The next several chapters of the book introduce the reader to some of the foundational principles of behavior analysis, with coverage from both the EAB and ABA perspectives. The final chapters of the book cover topics for which there has been ample basic, applied, and translational research conducted. The text concludes with a chapter on ethics, which includes content related to ethical issues in research, ethical issues in clinical practice, and the ethical use of nonhuman animals and special populations in research"--
Download or read book The Neuroscience of Autism Spectrum Disorders written by Joseph D. Buxbaum and published by Academic Press. This book was released on 2012-10-25 with total page 494 pages. Available in PDF, EPUB and Kindle. Book excerpt: Autism is no longer considered a rare disease, and the Center for Disease Control now estimates that upwards of 730,000 children in the US struggle with this isolating brain disorder. New research is leading to greater understanding of and ability to treat the disorder at an earlier age. It is hoped that further genetic and imaging studies will lead to biologically based diagnostic techniques that could help speed detection and allow early, more effective intervention. Edited by two leaders in the field, this volume offers a current survey and synthesis of the most important findings of the neuroscience behind autism of the past 20 years. With chapters authored by experts in each topic, the volume explores etiology, neuropathology, imaging, and pathways/models. Offering a broad background of ASDs with a unique focus on neurobiology, the volume offers more than the others on the market with a strictly clinical focus or a single authored perspective that fails to offer expert, comprehensive coverage. Researchers and graduate students alike with an interest in developmental disorders and autism will benefit, as will autism specialists across psychology and medicine looking to expand their expertise. Uniquely explores ASDs from a neurobiological angle, looking to uncover the molecular/cellular basis rather than to merely catalog the commonly used behavioral interventions Comprehensive coverage synthesizes widely dispersed research, serving as one-stop shopping for neurodevelopmental disorder researchers and autism specialists Edited work with chapters authored by leaders in the field around the globe - the broadest, most expert coverage available
Download or read book Translational Anatomy and Cell Biology of Autism Spectrum Disorder written by Michael J. Schmeisser and published by Springer. This book was released on 2017-05-25 with total page 211 pages. Available in PDF, EPUB and Kindle. Book excerpt: Autism spectrum disorder (ASD) affects approximately 1 % of the human population and is characterized by a core symptomatology including deficits in social interaction and repetitive patterns of behaviour plus various co-morbidities. Although a lot of progress has been made to uncover underlying causes and mechanisms throughout the last decade, we are still at the very beginning to understand this enormously complex neurodevelopmental condition. This special volume is focused on translational anatomy and cell biology of ASD. International experts from the field including several members of the EU-AIMS initiative launched by the European Union to develop novel treatments for ASD have contributed chapters on several topics covering all crucial aspects of translational ASD research with a special emphasis on ASD model systems including stem cells and animals. Primary objective is to clarify how anatomical and cell biological phenotypes of ASD will help to translate basic mechanisms to clinical practice and to efficiently treat affected individuals in the near future.
Download or read book Research Approaches to Supporting Students on the Autism Spectrum in Inclusive Schools written by Suzanne Carrington and published by Routledge. This book was released on 2021-05-18 with total page 141 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book will support researchers in the field of education disability by outlining inclusive research approaches and their challenges, outcomes, and impact. Each chapter reports on school/university-based research supporting inclusion for young people on the autism spectrum. This research has been developed in Australian schools with students, families, teachers, and specialists. The intent of this approach is to mobilise new knowledge to the benefit of all students, including students on the autism spectrum, their families, teachers, and school communities. This book showcases how research can be more inclusive with a move to collaborative, participatory, and co-produced research that will impact on young people, families, and educators. The authors highlight the complex challenges and the positive outcomes of conducting research in inclusive ways and provide detailed practical strategies for researchers. Inclusive education is socially, emotionally, and academically beneficial for all students and positively impacts on respectful attitudes to difference. This book provides a groundbreaking approach to research that by design is inclusive and therefore provides an invaluable opportunity for building the foundations of an inclusive society for all. This book will be invaluable to researchers, educators, and professional learning in schools.
Download or read book A Time for Metabolism and Hormones written by Paolo Sassone-Corsi and published by Springer. This book was released on 2016-04-04 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent years have seen spectacular advances in the field of circadian biology. These have attracted the interest of researchers in many fields, including endocrinology, neurosciences, cancer, and behavior. By integrating a circadian view within the fields of endocrinology and metabolism, researchers will be able to reveal many, yet-unsuspected aspects of how organisms cope with changes in the environment and subsequent control of homeostasis. This field is opening new avenues in our understanding of metabolism and endocrinology. A panel of the most distinguished investigators in the field gathered together to discuss the present state and the future of the field. The editors trust that this volume will be of use to those colleagues who will be picking up the challenge to unravel how the circadian clock can be targeted for the future development of specific pharmacological strategies toward a number of pathologies.
Download or read book Autistic Spectrum Disorders in Children written by Vidya Bhushan Gupta and published by CRC Press. This book was released on 2004-03-19 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: Impeccably researched and written by a nationally known team of specialists from neurodevelopmental pediatrics, psychology, epidemiology, education, occupational therapy, and speech therapy backgrounds, Autistic Spectrum Disorders in Children presents a multidisciplinary profile of autism and pervasive developmental disorders in children. Tracing the history of autism and tracking the latest research on its causation and neurological basis, this volume offers both traditional medical and complementary and alternative medicine approaches-as well as reliable methods for assessing treatment efficacy.
Download or read book Pharmacological Modulation of Excitation Inhibition Balance in Autism Spectrum Disorders written by Laura Ann Ajram and published by . This book was released on 2018 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: However, riluzole had no measurable effect on glutamate nor GABA efflux in either wild type, or Neurexinl a knock out rats. Overall, I have, for the first time, identified that E-1 balance at both the intracellular and functional level may be shifted in adult men with ASD, and that the brain in ASD is pharmacologically different to that of controls. This has implications for future drug discovery in ASD and the results of this thesis could be translated forwards to enhance future clinical trial design. Further to this, I found the Neurexinl a knock out rat to have a comparable baseline biology to the human condition, which may support its use in future studies of back-translate these findings. Such work will be necessary to further understand EI pharmacology in ASD, and further validate E-I balance as a tractable therapeutic treatment target for this increasingly prevalent condition.
Download or read book Translational Neuroscience written by James Elmer Barrett and published by Cambridge University Press. This book was released on 2012-06-28 with total page 379 pages. Available in PDF, EPUB and Kindle. Book excerpt: Translational neuroscience is at the heart of clinical advancement in the fields of psychiatry, neurology and neurodevelopmental disorders. Written and edited by leading scientists and clinicians, this is a comprehensive and authoritative analysis of this emerging strategy for developing more effective treatments for brain disorders. Introductory chapters bring together perspectives from both academia and industry, while subsequent sections focus on disease groups, including bipolar disorder and depression, attention deficit hyperactivity disorder, substance abuse, autism, Alzheimer's disease, pain, epilepsy, Parkinson's disease and multiple sclerosis. Each section includes topical introductory and summary chapters, providing an overview and synthesis of the field. Translational Neuroscience: Applications in Psychiatry, Neurology, and Neurodevelopmental Disorders is an important text for clinicians, scientists and students in academic settings, government agencies and industry, as well as those working in the fields of public health and the behavioural sciences.
Download or read book Autism written by and published by Academic Press. This book was released on 2020-07-23 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: Autism, Volume 173 in the Progress in Molecular Biology and Translational Science series, provides the most topical, informative and exciting monographs available on a wide variety of research topics. Chapters in this new release include updates on atypical brain development in autism spectrum disorder, predicting early diagnosis of autism spectrum disorder using neural and behavioral measures, the roles of the endocannabinoid system in autism spectrum disorder, the neurobiology of sensory processing in autism spectrum disorder, the effects of oxytocin administration on individuals with ASD, resting-state abnormalities of posterior cingulate in autism spectrum disorder, and more. Includes comprehensive coverage of molecular biology Presents ample use of tables, diagrams, schemata and color figures to enhance the reader's ability to rapidly grasp the information provided Contains contributions from renowned experts in the field
Download or read book Autism Service Delivery written by Florence D. DiGennaro Reed and published by Springer. This book was released on 2015-09-09 with total page 495 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume examines ways in which service delivery to individuals with autism can be improved from both ends of the basic-applied research spectrum. It introduces the concept of translational scholarship and examines real-world value in developing relevant interventions. Each area of coverage reviews current findings on autism from basic research and, then, discusses the latest applied research literature to create a roadmap for researchers, clinicians, and scientist-practitioners to develop new, effective strategies as children, adolescents, and adults with autism continue to learn and grow. Featured coverage includes: Why practice needs science and how science informs practice. The social learning disorder of stimulus salience in autism. Assessment and treatment of problem behaviors associated with transitions. Understanding persistence and improving treatment through behavioral momentum theory. The behavioral economics of reinforcer value. Increasing tolerance for delay with children and adults with autism. Autism Service Delivery is an essential resource for researchers, clinicians and scientist-practitioners, and graduate students in the fields of developmental psychology, behavioral therapy, social work, clinical child and school psychology, occupational therapy, and speech pathology.
Download or read book Oxytocin Vasopressin and Related Peptides in the Regulation of Behavior written by Elena Choleris and published by Cambridge University Press. This book was released on 2013-04-11 with total page 409 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comparative overview of the effects of neuropeptides on behavior, examining parallel findings in both humans and non-human animals.
Download or read book Textbook of Autism Spectrum Disorders Second Edition written by Eric Hollander, M.D. and published by American Psychiatric Pub. This book was released on 2022-03-15 with total page 744 pages. Available in PDF, EPUB and Kindle. Book excerpt: More than 40 years after the official recognition of infantile autism in DSM-III, advances continue to be made in our understanding of the possible causes, assessment and evaluation, and treatment of autism spectrum disorder (ASD). With contributions by dozens of experts in the field, this second edition of the Textbook of Autism Spectrum Disorders has been updated to reflect the latest research in ASD. Unrivaled in its thoroughness, this volume discusses issues of assessment and evaluation; examines the etiology of ASD and its recognized associations with other medical conditions; analyzes standard and experimental treatments; and delves into social policy issues pertinent to individuals with ASD and those who treat them. With summary points in each chapter and copious lists of recommended readings, this is an indispensable resource for psychiatrists, psychologists, neurologists, social workers, speech therapists, educators, and all others in the continuum of care.
Download or read book Translational Neuroimaging written by Robert A. McArthur and published by Academic Press. This book was released on 2012-10-26 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers methodical issues in human and animal neuroimaging translational research as well as detailed applied examples of the use of neuroimaging in neuropsychiatric disorders and the development of drugs for their treatment. Offering an accompanying website with illustrations and text available for further knowledge and presentations, Translational Neuroimaging: Tools for CNS Drug Discovery, Development and Treatment appeals to non-clinical and clinical neuroscientists working in and studying neuropsychiatric disorders and their treatment as well as providing the novice researcher or researcher outside of his/her expertise the opportunity to understand the background of translational research and the use of imaging in this field. Provides a background to translational research and the use of brain imaging in neuropsychiatric disorders.
Download or read book Clinical Handbook of Behavioral Sleep Treatment in Children on the Autism Spectrum written by Laurie K McLay and published by Springer Nature. This book was released on 2022-10-28 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook provides an overview of the nature, prevalence, and causes of sleep problems in children with autism spectrum disorder (ASD) and examines the process of using functional behavior assessment (FBA) to treat sleep disorders. It describes several evidence-based treatments and explores how these align with the outcomes of the FBA process, including case illustrations of the assessment and treatment process. The handbook discusses the application of FBA in family contexts, including: The effects on children and families of successful interventions with sleep. How to conduct FBA with clinically complex families. Including the child in the intervention. The evidence of efficacy of other treatment approaches. The handbook addresses sleep problems that are highly prevalent among children and young people with ASD, including sleep onset delay, frequent and prolonged night waking, and unwanted co-sleeping. It explores the profound secondary effects that sleep problems may have on children’s daytime functioning as well as child and parent health and wellbeing. The handbook discusses the causes of sleep problems in individuals with ASD, which may be multifaceted and complex and include physiological, environmental, cognitive etiologies yet almost always have a behavioral or learned component. It examines how FBA can be used to characterize challenging behaviors and identify the antecedents (e.g., environmental context) and consequences that affect such behaviors. The volume details the process of using FBA to assess and treat sleep problems in children with ASD. Clinical Handbook of Behavioural Sleep Treatment in Autism is a must-have resource for clinicians, therapists, and other practitioners as well as researchers and graduate students in clinical child and school psychology, behavioral therapy, social work, public health, developmental psychology, pediatrics, family studies, and child and adolescent psychiatry.
