Download or read book Translational Advances in Gynecologic Cancers written by Michael Birrer and published by Academic Press. This book was released on 2017-01-25 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: Translational Advances in Gynecologic Cancers straddles the bench and bed divide by highlighting important and interesting research that is translatable to the clinic. The contents of this book cover the entire spectrum, from promising laboratory based research, to clinical trial efforts. Further, new therapeutic indications based upon randomized phase III trials are also included. Clinicians will learn about lab-based science that is about to enter the clinic, along with the rationale behind translational endpoints in trials. Researchers will be able to identify and understand the clinical needs of patients with these types of tumors to improve their research focus. Provides a comprehensive description of all evolving translational gynecologic cancer research for clinicians Identifies knowledge gaps to inform the next research direction Ties together clinical research and patient needs to help both the researcher and clinician Addresses genomics, new target therapies, novel tools, and more for ovarian, endometrial, and cervical cancer

Download or read book Molecular Diagnosis and Targeting for Gynecologic Malignancy written by Seiji Isonishi and published by Springer Nature. This book was released on 2021-03-05 with total page 171 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book summarizes the important developments in the field of cancer research, specifically uterine cervical/endometrial cancer and ovarian cancer. It highlights the recent advances in gynecologic cancer, such as next generation models of genetically engineered animal models or cancer cell lines, focusing on their significance for advancing our understanding of gynecologic cancer biology, prevention and treatment, and drug response and resistance. Cancer research in the area of gynecologic tumors has undergone an enormous transformation over the past decade, with a greater understanding of tumor biology, elucidation of novel targets for therapeutic intervention, and better recognition of genetic predisposition syndromes. At the same time, the recent advances in basic cancer research have provided key insights into all aspects of gynecologic cancer biology, including developmental pathways and the impact of lineage plasticity, understanding metastatic progression, uncovering the roles of the tumor microenvironment , exploring tumor evolution, and discovering new therapeutic approaches and mechanisms of drug sensitivity and adaptive response. Molecular Diagnosis and Targeting for Gynecologic Malignancy appeals to investigators, clinicians, residents and postdocs who are curious about new research on gynecologic malignancies. It not only presents basic and translational research, but also explores the generalizability of the evidence covering the interface between basic and clinical science. Furthermore, a number of the topics offer the basis for new ideas that have the potential to advance into the gynecologic malignancies. This book provides readers with state-of-the-art information that will help improve the lives of patients with these challenging diseases.

Download or read book Gynecologic Oncology written by Robert F. Ozols and published by Springer Science & Business Media. This book was released on 2013-03-14 with total page 393 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, there have been major advances in the treatment of patients with gynecologic malignancies. Perhaps the biggest advances have been in the area of ovarian cancer. Gynecologic Oncology focuses primarily upon this malignancy. This volume discusses cytoreductive surgery; screening for ovarian cancer; chemotherapy; new chemotherapeutic drugs; the controversy regarding the role of high-dose chemotherapy in gynecologic cancers; the hereditary basis for gynecologic malignancies; molecular genetics; molecular biology and new biologic therapies. Other topics covered are the treatment of all stages of cervical cancer, including radiotherapy. In addition, a chapter on advances in the pathology of gynecologic cancers is included. The advances made in the treatment of gynecologic malignancies are due, in part, to the clinical studies performed by many of the contributors to this volume. Clinical advances have been the result of multidisciplinary approaches which involve molecular biologists, pathologists, radiation therapists, surgeons and chemotherapists. Future advances will continue to rely upon collaborative interaction among these different disciplines.

Download or read book Ovarian Cancers written by Eric Pujade-Lauraine and published by Springer. This book was released on 2016-10-17 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an overview of the latest developments in the concepts and management of ovarian cancer. The new data presented throughout opens the way to radically different therapeutic approaches. Surgery remains the core of ovarian cancer treatment, but its ultimate goal and the standard surgical procedure have evolved, giving rise to the question of how to label expert centers for debulking surgery. Neo-adjuvant chemotherapy is becoming more popular and is also a new field for testing novel drug combinations. Over recent years, ovarian cancer management has embraced molecular biology. It is now more correct to talk about cancers of the ovary rather than ovarian cancer, since it is not a unique disease but several entities with different molecular drivers. The significant advances in drugs targeting the microenvironment or the tumor cell DNA repair mechanisms are presented in detail together with exciting future perspectives. All these advances would not have been possible without collaborative groups such as the GINECO group in France and their integration in wider clinical research networks at the European (ENGOT) and international (GCIG) level.

Download or read book Gynecologic Cancer written by Loren K. Mell, MD and published by Demos Medical Publishing. This book was released on 2011-12-20 with total page 141 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radiation therapy is a major tool in the management of this family of cancers.. This issue of Radiation Medicine Rounds includes reviews of all major recent advances in treatment of gynecologic cancer. Articles also review current knowledge in the areas of biologic agents, Intensity Modulated Radiation Therapy, Image-Guided Brachytherapy, and robotic surgery in gynecologic cancer. This issue of RMR will provide the practitioner with a full current overview of the present best practices and recent research in management of this complex and challenging family of cancers.

Download or read book Gynecologic Cancer Care Innovative Progress written by Carolyn Y. Muller and published by Elsevier Health Sciences. This book was released on 2019-01-23 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: In consultation with Dr. William Rayburn, Dr. Muller has put together an issue designed to educate the reader on the rapid progress in Gynecologic Cancer Care. More than any other field in obstetrics and gynecology, gynecologic oncology has seen an explosion in integrated drug development and technology, including personalized medicine, germline and somatic testing, targeted therapeutics, biologic and immunotherapies, improved robotic technology, and a paradigm shift towards “less is more. Evolving data in quality measures including enhanced surgical recovery, integrative palliative care, and survivorship management has strengthened the need for a seemless team approach to the care of our patients. Despite the complexity and rapid discoveries leading to significant change in practice, the dedication to patients is the driver to stay up to date and participate in the research and clinical trials that lead to the cancer care advances that are substantial in this update. Expert authors have contributed articles on the following topics: Trends in Gynecologic Cancer Care in North America: Safety, Value and Quality; Cancer Screening and Prevention Highlights in Gynecologic Cancer; Germline and Somatic Tumor Testing in Gynecologic Cancer Care; Less is More: Minimally Invasive and Quality Surgical Management of Gynecologic Cancer; Ovarian Cancer: Clinical Trial Breakthroughs and Impact on Management; Endometrial Cancer: Obesity, Genetics and Targeted Trials; Cervical Cancer: A Global and Access to Care Crisis; Vulvar and Vaginal Cancer; Gestational Trophoblastic Neoplasia; Chemotherapy, Biologic and Immunotherapy Breakthroughs in Cancer Care; Palliative Care in Gynecologic Oncology; Personalized Medicine in Gynecologic Cancer: Fact or Fiction; and Survivorship Care in Gynecologic Cancer.

Download or read book Ovarian Cancers written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2016-04-25 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt: In an era of promising advances in cancer research, there are considerable and even alarming gaps in the fundamental knowledge and understanding of ovarian cancer. Researchers now know that ovarian cancer is not a single disease-several distinct subtypes exist with different origins, risk factors, genetic mutations, biological behaviors, and prognoses. However, persistent questions have impeded progress toward improving the prevention, early detection, treatment, and management of ovarian cancers. Failure to significantly improve morbidity and mortality during the past several decades is likely due to several factors, including the lack of research being performed by specific disease subtype, lack of definitive knowledge of the cell of origin and disease progression, and incomplete understanding of genetic and non-genetic risk factors. Ovarian Cancers examines the state of the science in ovarian cancer research, identifies key gaps in the evidence base and the challenges to addressing those gaps, considers opportunities for advancing ovarian cancer research, and examines avenues for translation and dissemination of new findings and communication of new information to patients and others. This study makes recommendations for public- and private-sector efforts that could facilitate progress in reducing the incidence of morbidity and mortality from ovarian cancers.

Download or read book The 21st Century Handbook of Clinical Ovarian Cancer written by Krishnansu S Tewari and published by Springer. This book was released on 2015-01-13 with total page 211 pages. Available in PDF, EPUB and Kindle. Book excerpt: A thorough review on ovarian cancer, treatment guidelines and emerging therapies available for the disease. The book was originally commissioned due to recent developments in therapies for ovarian cancer. This concise pocket book will review ovarian cancer’s epidemiology, clinical features, diagnosis and medical management. Busy healthcare professionals will benefit from this text, which will not only cover the foundation of ovarian cancer management, but discuss up-to-date national and international treatment guidelines and upcoming therapies.

Download or read book Gynecologic Cancer written by Patricia J. Eifel and published by Springer Science & Business Media. This book was released on 2006-04-19 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gynecologic cancer includes cancer of the female lower genital tract: vagina, vulva, cervix, endometrium, uterus, and ovaries. Gynecologic Cancer is the fourth volume in the M.D. Anderson Cancer Care Series, featuring the current standard approach to gynecologic cancer care from the experts at M.D. Anderson Cancer Center. Designed for the practicing oncologist, this clinical guidebook allows for quick, authoritative access to the latest and best multimodality therapies. Topics covered in this volume include primary prevention and early detection, preinvasive diseases of female lower genital tract, pathology and imaging of gynecologica malignancies, treatment of vaginal, cervical, endometrial, uterine cancers. Discussions also address fertility-sparing options for treatment of women with gynecologica cancers as well as sexuality in women with gyn malignancies. Each of the 20 chapters ends with an up-to-date list of suggested readings, as well as "key practice points" highlighting the most principles and practices of each chapter for at-a-glance reference. More than 80 illustrations complement the text. This thorough, practical volume is the essential clinical guide for the oncologists, surgeons, and all physicians involved in the care of patients with gynecologic cancer.

Download or read book Gynecologic Cancers written by Kunle Odunsi, MD and published by Demos Medical Publishing. This book was released on 2013-10-09 with total page 315 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gynecologic Cancers summarizes issues related to the treatment of gynecologic cancer including descriptions of optimal multidisciplinary care utilizing all available modalities as well as related issues such as screening and prevention, management for special populations, psychological support and emerging directions in future treatment.

Download or read book Gynaecological Malignancies written by Gwo Yaw Ho and published by BoD – Books on Demand. This book was released on 2020-06-17 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt: “Gynaecological Malignancies - Updates and Advances” aims to present a review of the significant advances in the understanding and management of gynaecological malignancies. Major areas of importance in this field will be covered, incorporating new knowledge that has arisen due to the advancements in molecular techniques and the ability to correlate these molecular changes with clinical behaviour of gynaecologic tumours. The therapeutic implications of molecular subtyping to match appropriate therapies and the appreciation of the use of up to date radiotherapy techniques will be explored.

Download or read book Endometrial Cancer written by Ivan Diaz-padilla and published by . This book was released on 2014-01-01 with total page 178 pages. Available in PDF, EPUB and Kindle. Book excerpt: Endometrial cancer is the most common gynecological malignancy in women in developed countries. Most cases are generally diagnosed at an early-stage and curable with loco-regional therapies. Metastatic and/or recurrent disease still remains a therapeutic challenge and clearly represents an unmet medical need. Substantial progress has been made over the last decade in different fields of Gynecologic Oncology that has translated into a better understanding of the biology and clinical behavior of endometrial cancer and its management. Hence, this monograph provides a current overview of endometrial cancer spanning from its clinical epidemiology to molecular cancer therapeutics. The most relevant clinical aspects such as imaging, new surgical and radiation techniques, and the role of endocrine therapy and chemotherapy in the systemic treatment of endometrial cancer will also be discussed. With the contribution of internationally well-renowned experts in the field, this book will keep the reader abreast of the most recent advances in endometrial cancer from a multi-disciplinary perspective. This monograph is highly recommended for OB/GYN residents and fellows, nurse practitioners, junior faculty and all those interested in the field of womens cancer.

Download or read book Synopsis of Key Gynecologic Oncology Trials written by Malte Renz and published by CRC Press. This book was released on 2022-12-06 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: This revised and updated new edition of a best-selling text remains a fast and convenient overview of the clinical trials in gynecologic cancer treatment, outlining the evidence base of treatment decisions in uterine, ovarian, cervical, and vulvar cancers, and gestational trophoblastic neoplasia. Residents and fellows will find this book an indispensable reference, while practitioners will welcome it as a clarification of the evidence base for treatment options. *Gives a convenient summary of trials in gynecologic oncology *Supplies an invaluable revision primer for those undertaking certification *Provides a uniquely up-to-date resource

Download or read book Diagnosis and Treatment of Rare Gynecologic Cancers written by Michael Frumovitz and published by Elsevier Health Sciences. This book was released on 2022-05-10 with total page 387 pages. Available in PDF, EPUB and Kindle. Book excerpt: Offering a one-stop guide to recognition and therapeutic decision making, Diagnosis and Treatment of Rare Gynecologic Cancers fills a gap in the medical literature on uncommon ovarian, uterine, cervical, and vulvovaginal cancers and trophoblastic diseases. This authoritative text, edited by Drs. Michael Frumovitz, Mario Leitao, and Preetha Ramalingam, has been authored by internationally recognized experts from top institutions such as MD Anderson Cancer Center and Memorial Sloan Kettering Cancer Center. Each chapter covers different cancer subtypes and has been reviewed by an oncologist and a pathologist. Provides up-to-date clinical guidance on assessment and therapeutic options for patients with rare gynecologic malignancies. Presents information in a templated, easy-to-read format. Each chapter includes an introductory clinical case followed by epidemiology of disease, pathologic assessment, basic science/molecular/translational research, work-up of newly diagnosed disease, staging, treatment of newly diagnosed disease, treatment of recurrent disease, potential therapeutic targets, and a case resolution. Includes diagnostic and treatment algorithms for each form of cancer. Contains numerous anatomical figures, radiographs, photographs, and tables for quick visual reference.

Download or read book Controversies in the Management of Gynecological Cancers written by Jonathan A. Ledermann and published by Springer Science & Business Media. This book was released on 2013-12-13 with total page 347 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a novel text that highlights the controversial areas in the management of gynecological cancers. None of the topics in this book have definitive answers; they represent the everyday decision-making facing gynecologists, oncologists, radiologists, pathologists and other health professionals treating women with these conditions. This book is not to be used as a traditional textbook; it is a text that specialists and trainees will use to help them weigh up the arguments that exist in a variety of areas in the treatment of gynecological cancers. Each chapter will have two or more authors, selected either for their opposing views or for their ability to provide an opposite view or opinion to the other. The content will be evidence-based, illustrating contrasting evidence and scientific opinion in the literature. Each chapter will close on a summary indicating the direction of research needed to address the issues being discussed.

Download or read book Gynecologic Oncology written by Ramez N. Eskander and published by Springer. This book was released on 2014-11-17 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt: During this age of advanced technology, there is an incredible amount of dynamic literature surrounding the diagnosis and treatment of gynecologic cancers. Despite this information surplus, house officers and junior faculty studying gynecologic oncology indicate a need for a reliable, easily accessible, streamlined resource for everyday use. Gynecologic Oncology: A Pocketbook is a collaborative effort that combines the perspectives of expert faculty and fellows in training in the field of gynecologic oncology. Not only is it incredibly portable, but the format in which the information is presented (bullet point, outline, tables and diagrams) allows for rapid access to valuable information and is unique amongst existing texts. This distinct pocketbook will provide the information needed to care for patients with gynecologic malignancies appropriately and will promote critical thinking throughout treatment.

Download or read book Report of the Gynecologic Cancers Progress Review Group written by National Cancer Institute (U.S.). Gynecologic Cancers Progress Review Group and published by . This book was released on 2001 with total page 104 pages. Available in PDF, EPUB and Kindle. Book excerpt: