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Book Transferrin and the Trophic Effect of Nerves on Vertebrate Limb Regeneration

Download or read book Transferrin and the Trophic Effect of Nerves on Vertebrate Limb Regeneration written by William Robert Kiffmeyer and published by . This book was released on 1991 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Nerves and Tissue Repair

Download or read book Nerves and Tissue Repair written by and published by . This book was released on 1994 with total page 35 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report covers studies of regenerating peripheral nerves and the effect such nerves exert on regenerative growth of the tissue innervated. The iron-transport protein transferrin is an absolute requirement for cell proliferation and is abundant in peripheral nerves. The hypothesis investigated here is that transferrin is delivered axonally and is involved in the nerve-dependent cell proliferation which characterizes repair in avascular tissues. Amphibian (axoloti) limb regeneration is a well characterized model system for nerve-dependent reparative growth and was used here in experiments testing the hypothesis. Results include demonstrations that transferrin is present in both axons and Schwann cells of peripheral nerves, that the concentration of this factor increases greatly during regeneration, that transferrin is transported distally in regenerating axons at the expected rate for last axonal transport in amphibians, and is released at the growing tips of such axons. Previous work has shown that when nerves to regenerating axolotl limbs are transected the concentration of transferrin in the distal limb tissue declines rapidly and limb regeneration stops. These results strongly support the hypothesis that neural transferrin is important in nerve-dependent growth during vertebrate limb regeneration. Studies of both transferrin binding and expression of the transferrin gene in cells of axolotl peripheral nerve indicate that both uptake and synthesis of this factor occur in the regenerating nerve. These results have important implications for understanding the trophic effect of nerves in tissue repair.

Book International Review of Cytology

Download or read book International Review of Cytology written by and published by Academic Press. This book was released on 1998-04-16 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt: International Review of Cytology presents current advances and comprehensive reviews in cell biology--both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research. Gene Expression during Amphibian Limb Regeneration The Extracellular Matrix Biochemistry of Volvox The Cell Biology of Basophils Membrane Receptors for Endocytosis in the Renal Proximal Tubule

Book Principles of Regenerative Biology

Download or read book Principles of Regenerative Biology written by Bruce M. Carlson and published by Elsevier. This book was released on 2011-10-10 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the explosion of knowledge from molecular biology and the burgeoning interest in generating or regenerating tissues or organs through various bioengineering or stem cell approaches, many scientists and students have shown a renewed interest in the phenomenon of regeneration. Because relatively few have had the luxury of being able to approach the phenomenon of regeneration from a broad biological perspective, Dr. Carlson has produced a book that outlines the fundamental principles of regeneration biology. Subject matters focus principally on regeneration in vertebrate systems, but also invertebrate regeneration. In order to manipulate regenerative processes, it is important to understand the underlying principles of regeneration. Principles of Regnerative Biology is the key introductory reference for all developmental biologists, geneticists, and tissue and stem cell researchers. Creates a general understanding of one of the most fascinating and complex phenomena in biology Discusses the ability and diversity of regeneration in various organisms Explains the history and origins of cells in regenerating systems Includes information on stem cells and its important role in regeneration

Book Regulation of Vertebrate Limb Regeneration

Download or read book Regulation of Vertebrate Limb Regeneration written by Raymond E. Sicard and published by . This book was released on 1985 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: The regenerating vertebrate limb is an excellent model for exploring a number of significant questions in developmental biology. Written by leading investigators in the field, this collection provides a comprehensive discussion of the roles played by the major regulators affecting limbregeneration and repair following trauma. Using the amphibian limb as the recognized model system, the contributors explore in detail the contributions made by biopotentials, the skin, the endocrine system, and nerves in regulating such events as dedifferentiation, the proliferation of blastemacells , and pattern formation. The modulating roles of blood cells and the immune system are re-examined, and the exciting studies on the isolation and characterization of neurotropic factors reviewed. The sometimes provocative but always informative and up-to-date discussions provided in thisvolume will be of particular interest to developmental biologists, anatomists, neuroscientists, and cell biologists.

Book Dissertation Abstracts International

Download or read book Dissertation Abstracts International written by and published by . This book was released on 1992 with total page 698 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Regenerative Biology and Medicine

Download or read book Regenerative Biology and Medicine written by David L. Stocum and published by Elsevier. This book was released on 2010-07-26 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of the book is to bring together in one place the different facets of regenerative biology and medicine while providing the reader with an overview of the basic and clinically-oriented research that is being done. Not only does the content cover a plethora tissues and systems, it also includes information about the developmental plasticity of adult stem cells and the regeneration of appendages.As part of its balanced presentation, Regenerative Biology and Medicine does address the biological/bioethical issues and challanges involved in the new and exciting field of regenerative biology and medicine. *Tissues covered include skin, hair, teeth, cornea, and central neural types*Systems presented are digestive, respiratory, urogenital, musculoskeletal, and cardiovascular*Includes amphibians as powerful research models*Discusses appendage regeneration in amphibians and mammals

Book Regenerative Biology and Medicine

Download or read book Regenerative Biology and Medicine written by David L. Stocum and published by Academic Press. This book was released on 2012-06-07 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt: Regenerative Biology and Medicine, Second Edition — Winner of a 2013 Highly Commended BMA Medical Book Award for Medicine — discusses the fundamentals of regenerative biology and medicine. It provides a comprehensive overview, which integrates old and new data into an ever-clearer global picture. The book is organized into three parts. Part I discusses the mechanisms and the basic biology of regeneration, while Part II deals with the strategies of regenerative medicine developed for restoring tissue, organ, and appendage structures. Part III reflects on the achievements of regenerative biology and medicine; future challenges; bioethical issues that need to be addressed; and the most promising developments in regenerative medicine. The book is designed for multiple audiences: undergraduate students, graduate students, medical students and postdoctoral fellows, and research investigators interested in an overall synthesis of this field. It will also appeal to investigators from fields not directly related to regenerative biology and medicine, such as chemistry, informatics, computer science, mathematics, physics, and engineering. Highly Commended 2013 BMA Medical Book Award for Medicine Includes coverage of skin, hair, teeth, cornea, and central neural tissues Provides description of regenetive medicine in digestive, respiratory, urogenital, musculoskeletal, and cardiovascular systems Includes amphibians as powerful research models with discussion of appendage regeneration in amphibians and mammals

Book Regenerative Pharmacology

    Book Details:
  • Author : George J. Christ
  • Publisher : Cambridge University Press
  • Release : 2013-04-15
  • ISBN : 1107354730
  • Pages : 361 pages

Download or read book Regenerative Pharmacology written by George J. Christ and published by Cambridge University Press. This book was released on 2013-04-15 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: Regenerative medicine is broadly defined as the repair or replacement of damaged cells, tissues and organs. It is a multidisciplinary effort in which technologies derive from the fields of cell, developmental and molecular biology; chemical and material sciences (i.e. nanotechnology); engineering; surgery; transplantation; immunology; molecular genetics; physiology; and pharmacology. As regenerative medicine technologies continue to evolve and expand across the boundaries of numerous scientific disciplines, they remain at the forefront of the translational research frontier with the potential to radically alter the treatment of a wide variety of disease and dysfunction. This book will draw attention to the critical role that pharmacological sciences will undeniably play in the advancement of these treatments. This book is invaluable for advanced students, postdoctoral fellows, researchers new to the field of regenerative medicine/tissue engineering, and experienced investigators looking for new research avenues. The first state-of-the-art book in this rapidly evolving field of research.

Book American Doctoral Dissertations

Download or read book American Doctoral Dissertations written by and published by . This book was released on 1991 with total page 724 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Limb Regeneration

    Book Details:
  • Author : Panagiotis A. Tsonis
  • Publisher : Cambridge University Press
  • Release : 1996-07-13
  • ISBN : 9780521441490
  • Pages : 264 pages

Download or read book Limb Regeneration written by Panagiotis A. Tsonis and published by Cambridge University Press. This book was released on 1996-07-13 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first book that analyses the mechanisms of limb regeneration by incorporating the information obtained from older experiments with the many new recent advances in molecular and cellular biology.

Book Cellular and Molecular Basis of Regeneration

Download or read book Cellular and Molecular Basis of Regeneration written by Patrizia Ferretti and published by . This book was released on 1998-05-29 with total page 490 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides an extensive overview of the fundamental issues of regeneration, and surveys selected models throughout phylogenesis. Eighteen contributions integrate information obtained from anatomical and experimental embryology studies with that derived from cellular and molecular approaches, and genetics. The emphasis throughout is on how information accumulating from each of the models discussed is shedding light both on the mechanisms underlying regeneration, and on whether and how this could be translated into clinical practice. Annotation copyrighted by Book News, Inc., Portland, OR

Book Recent Trends in Regeneration Research

Download or read book Recent Trends in Regeneration Research written by V. Kiortsis and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 481 pages. Available in PDF, EPUB and Kindle. Book excerpt: Regeneration, i.e. the replacement of lost body parts by new outgrowths or by remodelling existing tissues, has been studied for centuries. However, in recent years important developments took place in this field too, owing to new soph isticated techniques and to novel theoretical concepts. Advances in Molecular Genetics, Biochemistry, Cell and Neurobiology, Immunology, to mention a few of them, are the main causes of this resurgence of interest in regeneration. As a consequence, more and more meetings and pUblications are devoted, either exclusively or for a large part, to basic and applied research of regenerative processes. "Regeneration ists" scattered in laboratories allover the world and accus tomed to know each other through exchange of reprints - occa sionally an encounter in a large conference - tend now to form small groups, even societies and to institutionalize their meetings. Although the critical mass of scientists involved in regeneration research does not seem yet to be reached, for an autonomous development of this sector, regular and frequent meetings of experts appear useful, even necessary. Such a meeting was convened in Saronis, near Athens, Greece, from 19 to 23 September 1988 and sponsored by the NATO Science Committee and the University of Athens. The present volume contains the contributions to this Advanced Research Workshop on "Recent Trends in Regeneration Research". About 50 biologists from different countries, either mem bers of the Alliance or outside it (U.R.S.S., India, Egypt, Switzerland, Sweden) took part, mostly as invited speakers.

Book Immunoneurology

    Book Details:
  • Author : Michel Chofflon
  • Publisher : Springer Science & Business Media
  • Release : 2012-12-06
  • ISBN : 3642611915
  • Pages : 265 pages

Download or read book Immunoneurology written by Michel Chofflon and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 265 pages. Available in PDF, EPUB and Kindle. Book excerpt: A considerable amount of information has been gathered in the field of immunoneurology over recent years. This knowledge about modifications in the pathways of neuroimmune diseases has enabled the development of new therapies. In this volume leading experts present the state of the art in the field, covering all aspects from basic science to the development of better therapies.

Book The Journal of Neuroscience

Download or read book The Journal of Neuroscience written by and published by . This book was released on 1987-07 with total page 700 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Spinal Cord Injury  SCI  Repair Strategies

Download or read book Spinal Cord Injury SCI Repair Strategies written by Giuseppe Perale and published by Woodhead Publishing. This book was released on 2019-10-30 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: Spinal Cord Injury (SCI) Repair Strategies provides researchers the latest information on potential regenerative approaches to spinal cord injury, specifically focusing on therapeutic approaches that target regeneration, including cell therapies, controlled drug delivery systems, and biomaterials. Dr. Giuseppe Perale and Dr. Filippo Rossi lead a team of authoritative authors in academia and industry in this innovative reference on the field of regenerative medicine and tissue engineering. This book presents all the information readers need to understand the current and potential array of techniques, materials, applications and their benefits for spinal cord repair. Covers current and future repair strategies for spinal cord injury repair Focuses on key research trends, clinics, biology and engineering Provides fundamentals on regenerative engineering and tissue engineering