Download or read book Transcriptional Regulation of One carbon Metabolism Genes of Saccharomyces Cerevisiae written by Seung-Pyo Hong and published by . This book was released on 1999 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Molecular Mechanisms in Yeast Carbon Metabolism written by Jure Piškur and published by Springer. This book was released on 2014-05-06 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Yeast is one of the most studied laboratory organisms and represents one of the most central models to understand how any eukaryote cell works. On the other hand, yeast fermentations have for millennia provided us with a variety of biotech products, like wine, beer, vitamins, and recently also with pharmaceutically active heterologous products and biofuels. A central biochemical activity in the yeast cell is the metabolism of carbon compounds, providing energy for the whole cell, and precursors for any of the final fermentation products. A complex set of genes and regulatory pathways controls the metabolism of carbon compounds, from nutrient sensing, signal transduction, transcription regulation and post-transcriptional events. Recent advances in comparative genomics and development of post-genomic tools have provided further insights into the network of genes and enzymes, and molecular mechanisms which are responsible for a balanced metabolism of carbon compounds in the yeast cell, and which could be manipulated in the laboratory to increase the yield and quality of yeast biotech products. This book provides a dozen of most comprehensive reviews on the recent developments and achievements in the field of yeast carbon metabolism, from academic studies on gene expression to biotechnology relevant topics.
Download or read book Reconstruction and Systems Analysis of Genome scale Metabolic and Regulatory Networks in Saccharomyces Cerevisiae written by Markus Juhana Herrgard and published by . This book was released on 2004 with total page 736 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Yeast Metabolic Engineering written by Valeria Mapelli and published by Humana Press. This book was released on 2014-04-18 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Yeast Metabolic Engineering: Methods and Protocols provides the widely established basic tools used in yeast metabolic engineering, while describing in deeper detail novel and innovative methods that have valuable potential to improve metabolic engineering strategies in industrial biotechnology applications. Beginning with an extensive section on molecular tools and technology for yeast engineering, this detailed volume is not limited to methods for Saccharomyces cerevisiae, but describes tools and protocols for engineering other yeasts of biotechnological interest, such as Pichia pastoris, Hansenula polymorpha and Zygosaccharomyces bailii. Tools and technologies for the investigation and determination of yeast metabolic features are described in detail as well as metabolic models and their application for yeast metabolic engineering, while a chapter describing patenting and regulations with a special glance at yeast biotechnology closes the volume. Written in the highly successful Methods in Molecular Biology series format, most chapters include an introduction to their respective topic, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls. Comprehensive and authoritative, Yeast Metabolic Engineering: Methods and Protocols aims to familiarize researchers with the current state of these vital and increasingly useful technologies.
Download or read book Yeast Sugar Metabolism written by Friedrich K. Zimmermann and published by CRC Press. This book was released on 1997-03-10 with total page 590 pages. Available in PDF, EPUB and Kindle. Book excerpt: Yeast Sugar Metabolism looks at the biomechanics, genetics, biotechnology and applications of yeast sugar. The yeast Saccharomyces cereisiae has played a central role in the evolution of microbiology biochemistry and genetics, in addition to its use of a technical microbe for the production of alcoholic beverages and leavening of dough.
Download or read book Introduction to Epigenetics written by Renato Paro and published by Springer Nature. This book was released on 2021-03-23 with total page 215 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access textbook leads the reader from basic concepts of chromatin structure and function and RNA mechanisms to the understanding of epigenetics, imprinting, regeneration and reprogramming. The textbook treats epigenetic phenomena in animals, as well as plants. Written by four internationally known experts and senior lecturers in this field, it provides a valuable tool for Master- and PhD- students who need to comprehend the principles of epigenetics, or wish to gain a deeper knowledge in this field. After reading this book, the student will: Have an understanding of the basic toolbox of epigenetic regulation Know how genetic and epigenetic information layers are interconnected Be able to explain complex epigenetic phenomena by understanding the structures and principles of the underlying molecular mechanisms Understand how misregulated epigenetic mechanisms can lead to disease
Download or read book Regulation of One carbon Metabolism in Saccharomyces Cerevisiae written by Matthew David Woidt Piper and published by . This book was released on 2000 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Frontiers in Bioprocesssing written by Subhas K. Sikdar and published by CRC Press. This book was released on 1989-11-30 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: The goal of Frontiers in Bioprocessing is twofold. First, it provides an in-depth discussion of recent developments in bioprocessing. Second, it focuses on the critical assessment of the potential of newer processing and separation techniques, including the concepts of overall process integration. This book intends to stimulate interactions among participants from various disciplinary backgrounds. It includes such topics as fermentation research, process control and measurement technology, and separation and purification in downstream processing. Those who will find this publication particularly of interest are bioengineers, biotechnologists, microbiologists, chemical engineers, as well as those studying these fields.
Download or read book Coordinate Regulation of Glycolytic Gene Expression in Saccharomyces Cerevisiae written by Chang Seo Park and published by . This book was released on 1994 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Gene Function Analysis written by Michael F. Ochs and published by Humana. This book was released on 2016-08-24 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The determination of protein function has been a major goal of molecular biology since the founding of the discipline. However, as we learn more about gene function, we discover that the context within which a gene is expressed controls the specific function of that gene. It has become critical to establish the background in which gene function is determined and to perform experiments in multiple applicable backgrounds. In Gene Function Analysis, Second Edition, a number of computational and experimental techniques are presented for identifying not only the function of an individual gene, but also the partners that work with that gene. The theme of data integration runs strongly through the computational techniques, with many focusing on gathering data from different sources and different biomolecular types. Experimental techniques have evolved to determine function in specific tissues and at specific times during development. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Gene Function Analysis, Second Edition seeks to serve both professionals and novices with a growing understanding of the complexity of gene function.
Download or read book Mechanisms of Gene Regulation written by Carsten Carlberg and published by Springer. This book was released on 2016-06-06 with total page 219 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook aims to describe the fascinating area of eukaryotic gene regulation for graduate students in all areas of the biomedical sciences. Gene expression is essential in shaping the various phenotypes of cells and tissues and as such, regulation of gene expression is a fundamental aspect of nearly all processes in physiology, both in healthy and in diseased states. This pivotal role for the regulation of gene expression makes this textbook essential reading for students of all the biomedical sciences, in order to be better prepared for their specialized disciplines. A complete understanding of transcription factors and the processes that alter their activity is a major goal of modern life science research. The availability of the whole human genome sequence (and that of other eukaryotic genomes) and the consequent development of next-generation sequencing technologies have significantly changed nearly all areas of the biological sciences. For example, the genome-wide location of histone modifications and transcription factor binding sites, such as provided by the ENCODE consortium, has greatly improved our understanding of gene regulation. Therefore, the focus of this book is the description of the post-genome understanding of gene regulation. The purpose of this book is to provide, in a condensed form, an overview on the present understanding of the mechanisms of gene regulation. The authors are not aiming to compete with comprehensive treatises, but rather focus on the essentials. Therefore, the authors have favored a high figure-to-text ratio following the rule stating that “a picture tells more than thousand words”. The content of the book is based on the lecture course, which is given by Prof. Carlberg since 2001 at the University of Eastern Finland in Kuopio. The book is subdivided into 4 sections and 13 chapters. Following the Introduction there are three sections, which take a view on gene regulation from the perspective of transcription factors, chromatin and non-coding RNA, respectively. Besides its value as a textbook, Mechanisms of Gene Regulation will be a useful reference for individuals working in biomedical laboratories.
Download or read book Molecular Characterization and Transcriptional Regulation of GCV3 the Saccharomyces Cerevisiae Gene Encoding the H protein of the Glycine Cleavage System written by Nagarajan Lakshmanan and published by . This book was released on 1997 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: YAL044, a gene on the left arm of Saccharomyces cerevisiae chromosome one, is shown to code for the H-protein subunit of the multienzyme glycine cleavage system. The gene designation has therefore been changed from YAL044 to GCV3 to reflect its role in the glycine cleavage system. GCV3 encodes a 177 amino acid residue protein with a putative mitochondrial targeting sequence at its amino terminus. Targeted gene replacement shows that GCV3 is not essential for growth on minimal media. It is, however, essential for growth when glycine serves as the sole nitrogen source. Studies of GCV3 expression revealed that it is highly regulated. Supplement with glycine, the glycine cleavage system's substrate, induced expression at least 30-fold. In contrast, addition of the C1-metabolic end products repressed expression about 10-fold. The regulation of glycine cleavage system activity reflects the availability of glycine and the cellular demand for its metabolic products. In addition the glycine cleavage system has been shown to be important for the growth and viability of organisms ranging from microorganisms such as E. coli and S. cerevisiae to humans. Although, this system is important and its activity highly regulated little was known about the transcriptional regulatory mechanisms that control its activity. To address this I have examined the transcriptional regulation of the S. cerevisiae GCV3 gene. The results presented here show that at least six different transcriptional activators control GCV3 expression. These include: an as yet unidentified activator that is partially responsible for its induction by glycine; Gcn4p the transcriptional activator that mediates general amino acid control; Gln3p which is involved in the activation of nitrogen regulated genes; Gcr1p, a transcription factor important for the expression of glycolytic genes; Bas1p/Bas2p which cooperatively mediates the glycine-dependent expression; and an as yet unidentified factor that represses expression regardless of the growth condition. Additional evidence suggests that Rap1p, Nil1p, Acr1p, Ure2p, and Da180p also regulate GCV3 regulation.
Download or read book Yeasts written by Alexandre Guilliermond and published by Merchant Books. This book was released on 2006-08-01 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Gene Regulation in Saccharomyces Cerevisiae written by Laura Balarezo Cisneros and published by . This book was released on 2020 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Yeast Stress Responses written by Stefan Hohmann and published by Springer Science & Business Media. This book was released on 2007-10-23 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt: Every cell has developed mechanisms to respond to changes in its environment and to adapt its growth and metabolism to unfavorable conditions. The unicellular eukaryote yeast has long proven as a particularly useful model system for the analysis of cellular stress responses, and the completion of the yeast genome sequence has only added to its power This volume comprehensively reviews both the basic features of the yeast genral stress response and the specific adapations to different stress types (nutrient depletion, osmotic and heat shock as well as salt and oxidative stress). It includes the latest findings in the field and discusses the implications for the analysis of stress response mechanisms in higher eukaryotes as well.
Download or read book Non conventional Yeasts from Basic Research to Application written by Andriy Sibirny and published by Springer. This book was released on 2019-08-12 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume scopes several aspects of non-conventional yeast research prepared by the leading specialists in the field. An introduction on taxonomy and systematics enhances the reader’s knowledge on yeasts beyond established ones such as Saccharomyces cerevisiae. Biotechnological approaches that involve fungal utilization of unusual substrates, production of biofuels and useful chemicals as citric acid, glutathione or erythritol are discussed. Further, strategies for metabolic engineering based on knowledge on regulation of gene expression as well as sensing and signaling pathways are presented. The book targets researchers and advanced students working in Microbiology, Microbial Biotechnology and Biochemistry.
Download or read book Transcriptional Regulation of Oxygen responsive Genes in Saccharomyces Cerevisiae written by Johanna Josephina Maria ter Linde and published by . This book was released on 2003 with total page 131 pages. Available in PDF, EPUB and Kindle. Book excerpt:
