Download or read book Transarterial Chemoembolization TACE Prior to Liver Transplantation Does it Add to Surgical Risk when Considering Marginal Grafts written by Amanda Boteon and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction:TACE is established tumour control measure in patients with hepatocellular carcinoma (HCC) prior to liver transplantation (LT). Loco-regional effects of TACE may adversely affect the technical aspects of LT, and hence implications for graft selection.Methods:Retrospective cohort study involving patients with HCC that underwent TACE before LT (TACE group) between January 2011 and December 2015. The outcome of this group was compared with patients that underwent LT for HCC but without preoperative TACE (NoTACE group). Post-transplant surgical morbidity was compared according to Clavien classification.Results:59 cases included in the TACE group were compared with 123 cases in the NoTACE group. TACE group had higher prevalence of ischaemia related native collateral damage (11.86% vs 0%; p=0.002), native hepatic artery occlusion identified at surgery (5.1% vs 0%;p=0.033) and adhesions between the necrotic tumour to adjacent structures (14.75% vs. 3.15%; p=0.005). Surgical morbidity rate was significantly higher in the TACE group considering Dindo-Clavien grade 2 complications (64.4% vs 47.2%; p=0.029), however this was not found for grade u2265 3 (45,8% vs 58,5%; p=0,105). Patients in the TACE group transplanted with grafts from donors after cardiac death had 8.7% 90-day mortality and 56.5% major complication rate compared to 6.7% and 65% for the NoTACE group (p=0.719 and p=0.475; respectively).Discussion:HCC patients undergoing TACE while in the LT waiting list may lead to complications related to the procedure experienced in the laparotomy, nevertheless it has not shown repercussions on the mortality and only partial impact at morbidity, even considering the use of marginal grafts.
Download or read book Hepato Pancreato Biliary and Transplant Surgery written by Quyen D Chu and published by Beaux Books Publishing, LLC. This book was released on 2018-01-08 with total page 1352 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique textbook provides a concise and practical approach to clinical dilemmas involving the liver, pancreas, and biliary tree. Six major sections encompass (1) Hepatic, (2) Biliary, (3) Pancreas, (4) Transplantation, (5) Trauma, and (6) Innovative Technology. Each topic is written by recognized experts from an "e;experiential"e; viewpoint combined with evidence-based medicine. The book contains over 170 chapters and over 350 contributors. It is relevant to Surgical Oncologists, Hepato-Pancreato-Biliary (HPB) Surgeons, Transplant Surgeons, Traumatologists, HPB Interventionalists, General Surgeons, and trainees and students. The title of each chapter is in a form of a clinical scenario and each chapter begins with a Case Scenario and ends with Salient Points. Special debates are included in each section. There are numerous compelling images, detailed illustrations, comprehensive tables, thorough algorithms, and other adjunctive tools that enhance learning. The authors emanate from different corners of the world. The book is a valuable resource for faculty, students, surgical trainees, fellows, and all health care providers in the HPB/Trauma/Transplant/Oncology fields.
Download or read book Living Donor Liver Transplantation 2nd Edition written by Sheung Tat Fan and published by World Scientific. This book was released on 2011-03-08 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book describes in detail the technical aspects of Living Donor Liver Transplantation (LDLT), the routine practice of the world renowned Liver Transplant Team at Hong Kong's Queen Mary Hospital, and our views on various issues of the operation. The thorough review on the history and technical procedures of LDLT and discussion on various aspects of the operation and its future perspectives will serve as a unique reference for surgeons, researchers, nurses, medical students, patients and laypersons seeking information on LDLT.This latest edition offers updated operative results from our center and the latest modifications of the technique. With contributions from a leading microvascular surgeon, a critical care clinician, a psychiatrist, and two anesthetists from the same liver transplant team, the LDLT experience at Queen Mary Hospital is depicted in an even greater extent.
Download or read book Diagnostic and Interventional Radiology in Liver Transplantation written by E. Bücheler and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume on liver transplantation is unique in the range of its coverage. Following introductory chapters on surgical and radiological anatomy, separate sections are devoted to organ donors and to adult and pediatric recipients. Surgical indications and techniques, the role of radiological modalities, and the treatment of complications are all fully discussed and illustrated.
Download or read book Liver Cancers written by Tim Cross and published by Springer. This book was released on 2018-12-12 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores in detail the primary liver cancers of hepatocellular carcinoma and cholangiocarcinoma examining the pathogenesis of disease along with diagnosis and current management options together with exploration of future treatment strategies and areas of controversy. Furthermore, the book highlights management of the common secondary malignancies and touches on benign liver tumours and how to best manage these. Written in a clear and didactic style, this volume includes summaries of the key learning points and questions so that the reader can gauge their knowledge and understanding. This book is aimed to broaden the knowledge base of primary care physicians, general physicians along with specialists in hepatology, oncology and hepato-biliary surgery
Download or read book Organ Grafts written by Roy Yorke Calne and published by Hodder Education. This book was released on 1975 with total page 100 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Liver Transplantation and Hepatobiliary Surgery written by Umberto Cillo and published by Springer Nature. This book was released on 2019-08-20 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past, liver resections and liver transplantations were performed by different surgical teams, with very little interplay between the two. However, the evolution toward more complex operations called for an increasingly intense interaction between these surgical techniques: split liver and living donor liver transplantation have become popular in the transplant community, utilizing the Coinaud segmental anatomy in a very sophisticated way, while portal and arterial resection and reconstruction have become indispensable methods for treating Klatskin tumors infiltrating the hepatic hilum. This book offers a complete overview of the connections between liver transplantation and hepatobiliary surgery. It focuses on ex situ techniques for resection of tumors at the suprahepatic confluence, with or without venous reconstruction, and on total vascular exclusion of the liver with the aid of a venovenous bypass that should be a surgical option for referral centers in hepatopancreatobiliary surgery. By taking into consideration the development of minimally invasive liver surgery, it will introduce readers to a variety of new perspectives such as: vascular exclusion techniques with or without extracorporeal circulation, hemodynamic implications and lessons learned from liver transplant surgery, and technical details on pediatric transplantation and its informative role in modern biliary tract surgery.
Download or read book Liver Malignancies written by C. Bartolozzi and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive and up-to-date overview of the role of diagnostic and interventional radiology in respect of liver malignancies. Following background chapters on anatomy, epidemiology, and clinicopathologic features, each of the diagnostic imaging techniques is carefully appraised, focusing on new developments in equipment and contrast agents. The interventional therapeutic approaches to primary and secondary hepatic malignancies are then discussed in depth, as well as such special topics as liver tumors in children and hepatic transplantation. Written by leading experts from around the world, this will prove to be an indispensable source of information for both clinicians and researchers.
Download or read book Hepatocyte Transplantation written by S. Gupta and published by Springer Science & Business Media. This book was released on 2002-09-30 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years there has been an increasing need for transplantation, but the number of donor livers available has increased only slightly, despite intensive public relations activities. New concepts in the field of transplantation, for instance the transplantation of living donor organs or the splitting of organs, are urgently required, to safeguard the treatment of patients with severe liver disease. The development and clinical application of cell therapy for patients with liver disease could soon present a significant enhancement of the therapeutic options. The aim of such cell therapy is to repair or improve the biological function of the chronically and acutely damaged liver. Even though systematic trials are not available, individual case reports and small series already show promising clinical results. Present concepts of cell therapy for liver diseases based on the use of primary hepatocytes have recently been considerably extended through new data on the biology of stem cells. The adult haematopoetic stem cell as a pool for hepatocyte grafts - what would be the perspectives for the clinical application? This book is the proceedings of the Falk Symposium No. 126 on `Hepatocyte Transplantation' (Progress in Gastroenterology and Hepatology Part III) held in Hannover, Germany, October 2-3, 2001, and is a forum for basic research, but also for questions concerning clinical applications in the field of hepatocyte transplantation.
Download or read book Liver Anesthesiology and Critical Care Medicine written by Gebhard Wagener and published by Springer. This book was released on 2018-04-11 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing anesthesiology for liver surgery and especially liver transplantation is highly complex and requires profound expertise in the physiology and pathophysiology of liver disease. This new edition incorporates the latest information in the field and remains the only available book on the topic. It focuses on the practical aspect of liver anesthesiology and critical care, while providing a comprehensive and in depth summary of the knowledge in this field. Most liver transplant centers now have dedicated teams providing anesthesia care during liver transplantations. In the last years there has been a substantial increase in knowledge and improvement in techniques in anesthesiology and critical care of patients undergoing liver surgery and transplant patients. Liver Anesthesiology and Critical Care Medicine, 2nd Edition includes new chapters on chronic liver failure and hepatic cirrhosis, preoperative risk assessment, evidence in liver anesthesiology, the splanchnic and systemic circulation in liver disease and a special focus on analgesia for liver resection including regional techniques. Written for anesthesiologists and critical care physicians caring for patients undergoing liver surgery and transplantation, this book proves to be an essential companion and review book as the number of liver surgeries with higher complexity continue to increase.
Download or read book Handbook of Hepato Pancreato Biliary Surgery written by Nicholas J. Zyromski and published by Lippincott Williams & Wilkins. This book was released on 2014-09-09 with total page 697 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook provides a comprehesive but succinct overview of medical and surgical management of diseases of the liver, pancreas, and biliary tree. It includes imaging of the pancreas and hepatobiliary system as well. Open and minimally invasive surgical management techniques are covered. Coverage includes pancreatic cancer and cysts, pancreatitis, complications of panreatic surgery, ultrasound for liver disease, cirrhosis and portal hypertension, neuroendocrine and colorectal metastases to the liver, gallstones, cholesystitis, infections in biliary surgery, and more. Target markets include surgical residents, surgical nurses, beginning fellows in HPB training programs. There may also be some uptake from gastroenterologists.
Download or read book Perioperative Medicine written by Steven L. Cohn and published by Springer Science & Business Media. This book was released on 2011-06-21 with total page 557 pages. Available in PDF, EPUB and Kindle. Book excerpt: Perioperative Medicine uses a concise, highly practical, bulleted format designed to ensure rapid comprehension of key concepts and reinforce the reader's understanding of complex topics in perioperative medicine. It contains authoritative, up-to-date coverage of the most essential concepts in perioperative care from preoperative risk assessment to postoperative follow-up. The Editor and his contributors use their expert insight and experience to provide an in-depth review of comorbid conditions, patient and surgery-specific risk assessment, and common postoperative complications. This new book reviews recent developments in the field, including published guidelines, and emphasizes an evidence-based, cost-effective approach designed to ensure quality, patient safety, and optimal outcomes. It is intended for use by hospitalists, general internists and subspecialists as well as anesthesiologists, surgeons, and residents in training who are caring for patients before and after surgery.
Download or read book Radiology Fundamentals written by Harjit Singh and published by Springer Science & Business Media. This book was released on 2011-12-02 with total page 347 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radiology Fundamentals is a concise introduction to the dynamic field of radiology for medical students, non-radiology house staff, physician assistants, nurse practitioners, radiology assistants, and other allied health professionals. The goal of the book is to provide readers with general examples and brief discussions of basic radiographic principles and to serve as a curriculum guide, supplementing a radiology education and providing a solid foundation for further learning. Introductory chapters provide readers with the fundamental scientific concepts underlying the medical use of imaging modalities and technology, including ultrasound, computed tomography, magnetic resonance imaging, and nuclear medicine. The main scope of the book is to present concise chapters organized by anatomic region and radiology sub-specialty that highlight the radiologist’s role in diagnosing and treating common diseases, disorders, and conditions. Highly illustrated with images and diagrams, each chapter in Radiology Fundamentals begins with learning objectives to aid readers in recognizing important points and connecting the basic radiology concepts that run throughout the text. It is the editors’ hope that this valuable, up-to-date resource will foster and further stimulate self-directed radiology learning—the process at the heart of medical education.
Download or read book Abdominal Sepsis written by Massimo Sartelli and published by Springer. This book was released on 2018-03-20 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book examines in detail the topic of sepsis, with a focus on intra-abdominal sepsis. Particular attention is devoted to source control in the management of the infection, antimicrobial therapy and sepsis support, which represent the cornerstones of treating patients with this problem. The importance of a multidisciplinary approach is highlighted not only by the instructive and informative sections on the acute manifestations of appendicitis, cholecystitis, and cholangitis, perforations and diverticulitis, Clostridium difficile infection and the role of candida in abdominal sepsis, but also by an extensive discussion of issues including antimicrobial resistance, damage control surgery, principles of antimicrobial therapy, hemodynamic support, adjunctive therapies, and thromboprophylaxis. Abdominal sepsis is the host’s systemic inflammatory response to intra-abdominal infections. It is associated with significant morbidity and mortality rates, and represents the second most common cause of sepsis-related mortality at intensive care units. Gathering contributions by authoritative experts from all around the world, this book will allow acute care surgeons, abdominal surgeons, intensive care clinicians, and students to broaden their understanding of intra-abdominal sepsis in daily clinical practice.
Download or read book Extreme Hepatic Surgery and Other Strategies written by Eduardo de Santibañes and published by Springer. This book was released on 2017-07-26 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the diagnoses; staging and management of patients with colorectal liver metastases initially considered unresectable and portrays the different strategies to increase resectability along with their tactics and tricks. Colorectal carcinoma is the third most commonly diagnosed cancer in the world and according to recent cancer statistics around 1.23 million patients are diagnosed each year. Of these patients, approximately 50% will develop liver metastases during the course of their disease and around 15-25% are found to have stage IV disease at diagnosis. Liver resection has been recognized as the treatment of choice for these patients, offering overall 5-year survival rates of up to 50-60% and the only hope for cure. However, at diagnosis only 10-20% of these patients are possibly amenable to surgical resection with curative intent. The possibility to achieve an R0 resection is many times limited by the amount and quality of the future liver remnant (FLR), being posthepatectomy liver failure (PHLF) the most feared and severe complication after major liver resections. With the years, diverse strategies have been developed with the intention to increase resectability by increasing the future liver remnant and/or reducing tumor size, e.g. ALPPS. Along with these techniques, associated surgeries are developed including multivisceral resections, which broadens even more the resectability for patients.
Download or read book Radiopharmaceuticals for Therapy written by F. F. (Russ) Knapp and published by Springer. This book was released on 2016-01-20 with total page 357 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides detailed information on therapeutic radiopharmaceuticals and discusses emerging technologies which have potential for broad clinical implementation. Recent advances in molecular biology, radiopharmaceutical chemistry and radioisotope production have stimulated a new era for the use of radiopharmaceuticals for targeted radionuclide therapy (TRT). Emerging clinical trials include use of peptides and monoclonal antibodies radiolabeled with therapeutic radionuclides for cancer therapy. In addition, small molecules are used for the treatment of chronic diseases such as metastatic bone pain palliation and radiation synovectomy of inflammatory joints. In the interventional arena, therapy of primary and metastatic liver cancer and arterial restenosis following angioplasty of both the coronary and peripheral arteries are being explored. Reactor and accelerator production of therapeutic radioisotopes is also integrated into these discussions. The development and use of radiopharmaceutical targeting characteristics required for treatment of specific disease processes and how these are implemented for radiopharmaceutical design strategies are also described. Radiopharmaceuticals for Therapy will benefit audiences in nuclear medicine and radionuclide therapy and will thus prove an invaluable source of up-to-date information for students, radiopharmaceutical scientists and professionals working in the radiopharmacy and nuclear medicine specialties.
Download or read book Guidelines on Hepatitis B and C Testing written by World Health Organization and published by World Health Organization. This book was released on 2017 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Testing and diagnosis of hepatitis B (HBV) and C (HCV) infection is the gateway for access to both prevention and treatment services, and is a crucial component of an effective response to the hepatitis epidemic. Early identification of persons with chronic HBV or HCV infection enables them to receive the necessary care and treatment to prevent or delay progression of liver disease. Testing also provides an opportunity to link people to interventions to reduce transmission, through counselling on risk behaviors and provision of prevention commodities (such as sterile needles and syringes) and hepatitis B vaccination. These are the first WHO guidelines on testing for chronic HBV and HCV infection and complement published guidance by WHO on the prevention, care and treatment of chronic hepatitis C and hepatitis B infection. These guidelines outline the public health approach to strengthening and expanding current testing practices for HBV and HCV, and are intended for use across age groups and populations.
