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Book Traitement des   motions et   tudes des liens entre la m  moire et les   motions dans la maladie d Alzheimer

Download or read book Traitement des motions et tudes des liens entre la m moire et les motions dans la maladie d Alzheimer written by Virginie Jacqueline Goutte and published by . This book was released on 2011 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: L’objectif de ce travail était 1) d’étudier le traitement des émotions dans différentes modalités sensorielles (visuelle et auditive) dans la maladie d’Alzheimer (MA), et 2) d’examiner les liens entre la mémoire et les émotions chez les patients MA. Dans une première expérience, nous avons exploré le traitement des émotions faciales et auditives. Nos résultats ont permis de mettre en évidence des déficits différents selon la modalité : les patients présentaient des difficultés pour identifier les émotions de colère, de peur, de dégoût et de tristesse sur des visages, alors que pour la modalité auditive, seule la joie était moins bien reconnue. Dans une deuxième expérience, nous avons utilisé une tâche d’amorçage d’identification perceptive de mots positifs, négatifs et neutres. Nous avons tout d’abord observé un effet d’amorçage perceptif préservé dans la MA. Par ailleurs, l’amplitude relative d’amorçage était plus importante pour les mots négatifs chez tous les sujets, ce qui suggère la présence d’un biais de positivité, préservé également dans la MA. Enfin, les mots connotés émotionnellement étaient mieux reconnus que les neutres par tous les sujets. L’expérience 3 consistait en une tâche d’amorçage subliminal avec effet de simple exposition pour des visages non familiers. Nous avons utilisé des paires amorces-cibles présentées soit deux fois, soit six fois, avec des amorces gaies, tristes ou neutres, et les cibles toujours neutres. Pour la tâche de préférence, les résultats ont montré qu’après 2 expositions, les participants préféraient les cibles aux distracteurs, lorsqu’elles avaient été associées à des amorces négatives. Par contre, après 6 expositions, les visages-cibles qui avaient été associés à visages-amorces positifs étaient préférés par tous les sujets. Ce travail de thèse a permis de mettre en évidence une perturbation du traitement des émotions faciales et auditives dans la MA. Cependant, un effet du matériel émotionnel sur la mémoire explicite et implicite a été mis en évidence chez les patients.

Book Effets des   motions sur la m  moire dans la maladie d Alzheimer et dans le viellissement normal

Download or read book Effets des motions sur la m moire dans la maladie d Alzheimer et dans le viellissement normal written by Alina-Alexandra Sava and published by . This book was released on 2015 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: L'effet des émotions sur la mémoire (EEM) est un effet largement documenté dans la littérature, en ce qui concerne les participants sains jeunes et âgés. Cette mise en évidence de meilleures performances mnésiques à partir de stimuli émotionnels par rapport à des stimuli neutres semblerait reposer sur l'existence de relations étroites entre les régions cérébrales primordiales dans les processus mnésiques et émotionnels ; soit respectivement l'hippocampe et l'amygdale. Ces deux structures étant parmi les premières touchées au cours de la maladie d'Alzheimer (MA), leur altération pourrait sous-tendre la défaillance de l'EEM chez ces patients. Toutefois, les résultats des études ayant exploré l'EEM chez les patients MA sont assez contradictoires. Cette divergence entre les résultats concernerait notamment les études ayant exploré l'EEM avec des intervalles courts entre l'encodage et la récupération. L'objectif de cette thèse est ainsi d'étudier les facteurs susceptibles d'être responsables de ces résultats hétérogènes. L'analyse de la littérature a suggéré que l'un de ces facteurs pourrait être lié aux conditions très variables d'encodage utilisées dans différentes recherches. Ainsi, notre première étude comportementale a apporté des arguments robustes quant à la dépendance de l'EEM, et en particulier de l'effet de positivité en mémoire, de l'intentionnalité et de la quantité de ressources cognitives allouées à l'encodage ; mais ceci chez les participants âgés sains seulement. En effet, dans cette première étude, l'EEM n'a pas être observé dans le groupe de patients MA étudié. L'analyse détaillée de ces résultats a soulevé diverses interrogations, chacune d'entre elles faisant l'objet d'une nouvelle étude expérimentale. Ainsi, dans les études suivantes, l'influence de quatre facteurs pouvant influer sur l'EEM dans la MA fut au centre de nos recherches; soit respectivement le degré d'atrophie des régions médio-temporales, la profondeur du traitement, la disponibilité des ressources attentionnelles pendant l'encodage, et la familiarité ressentie envers les stimuli. L'ensemble des résultats de ces quatre dernières études convergerait vers l'idée que l'EEM, et notamment l'effet de positivité en mémoire, serait préservé chez les patients MA quand certaines conditions sont remplies. Ainsi, cet effet semble relativement préservé chez les patients MA ne présentant pas de degrés d'atrophie des régions amygdaliennes et hippocampiques trop importants. Par ailleurs, comme chez les participants âgés sains, l'effet de positivité en mémoire semblerait se manifester chez les patients MA en dehors et au-delà du sentiment de familiarité ressenti envers les stimuli positifs, notamment lors de l'utilisation de tâches d'encodage permettant le traitement profond des stimuli, et lors de tâches de mémoire de travail simples. De même, les stimuli émotionnels négatifs très intenses sembleraient moduler les stratégies de réponse employées par les patients MA dans les tâches de reconnaissance, mais aussi les performances mnésiques de ces patients dans des tâches de mémoire de travail.

Book Permanent Present Tense

Download or read book Permanent Present Tense written by Suzanne Corkin and published by Basic Books. This book was released on 2013-05-14 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1953, 27-year-old Henry Gustave Molaison underwent an experimental "psychosurgical" procedure -- a targeted lobotomy -- in an effort to alleviate his debilitating epilepsy. The outcome was unexpected -- when Henry awoke, he could no longer form new memories, and for the rest of his life would be trapped in the moment. But Henry's tragedy would prove a gift to humanity. As renowned neuroscientist Suzanne Corkin explains in Permanent Present Tense, she and her colleagues brought to light the sharp contrast between Henry's crippling memory impairment and his preserved intellect. This new insight that the capacity for remembering is housed in a specific brain area revolutionized the science of memory. The case of Henry -- known only by his initials H. M. until his death in 2008 -- stands as one of the most consequential and widely referenced in the spiraling field of neuroscience. Corkin and her collaborators worked closely with Henry for nearly fifty years, and in Permanent Present Tense she tells the incredible story of the life and legacy of this intelligent, quiet, and remarkably good-humored man. Henry never remembered Corkin from one meeting to the next and had only a dim conception of the importance of the work they were doing together, yet he was consistently happy to see her and always willing to participate in her research. His case afforded untold advances in the study of memory, including the discovery that even profound amnesia spares some kinds of learning, and that different memory processes are localized to separate circuits in the human brain. Henry taught us that learning can occur without conscious awareness, that short-term and long-term memory are distinct capacities, and that the effects of aging-related disease are detectable in an already damaged brain. Undergirded by rich details about the functions of the human brain, Permanent Present Tense pulls back the curtain on the man whose misfortune propelled a half-century of exciting research. With great clarity, sensitivity, and grace, Corkin brings readers to the cutting edge of neuroscience in this deeply felt elegy for her patient and friend.

Book The Making of Modern Psychiatry

Download or read book The Making of Modern Psychiatry written by Ronald Chase and published by Logos Verlag Berlin GmbH. This book was released on 2018 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of psychiatry changed dramatically in the latter half of the nineteenth century, largely by embracing science. The transformation was most evident in Germany, where many psychiatrists began to work concurrently in the clinic and the laboratory. Some researchers sought to discover brain correlates of mental illness, while others looked to experimental psychology for insights into mental dynamics. Featured here, are the lives and works of Emil Kraepelin - often considered the founder of modern scientific psychiatry, his teacher Bernhard Gudden, and his anatomist colleague Franz Nissl. The book describes scientific findings together with the methods used; it explains why diagnoses were then (and are still now) so difficult to make; it also explores mind-brain controversies. The Making of Modern Psychiatry will inform and delight mental health professionals as well as all persons curious about the origins of modern psychiatry. ``Ronald Chase has provided fascinating information about the 19th century scientists' thinking on behavioral disorders: how to identify them, how to treat them, how to understand them ... He is a terrific writer and has compiled very interesting stories that bring to life the thinking of the time and the condition of serious mental illnesses in their first stages of understanding ... The author weaves the work of the 20th to 21st centuries nicely into his story ... gives optimism for a brain-based understanding in the future.'' Carol Tamminga, M.D. Professor and Chair, Department of Psychiatry, University of Texas Southwestern Medical Center

Book Rehabilitation of the Spine

Download or read book Rehabilitation of the Spine written by Craig Liebenson and published by Lippincott Williams & Wilkins. This book was released on 2007 with total page 992 pages. Available in PDF, EPUB and Kindle. Book excerpt: The foremost authorities from chiropractics, orthopaedics and physical therapy present a practical overview of spinal rehabilitation. This clinical resource presents the most current and significant spinal rehab information, showing how to apply simple and inexpensive rehabilitation in the office. The updated Second Edition includes clinical/regional protocols and chapters on diagnostic triage, acute care, functional assessment, recovery care, outcomes, and biopsychosocial aspects. A bonus DVD offers demonstrations of key therapies and procedures.

Book Severe Dementia

    Book Details:
  • Author : Alistair Burns
  • Publisher : John Wiley & Sons
  • Release : 2006-05-12
  • ISBN : 047001055X
  • Pages : 260 pages

Download or read book Severe Dementia written by Alistair Burns and published by John Wiley & Sons. This book was released on 2006-05-12 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: The later stages of dementia are as important, if not more so, as the earlier stages, since they harbour unique characteristics and events, which profoundly affect the lives of patients and their carers. Severe dementia has not had a high profile in the clinical literature as until recently prognosis was poor and there were few beneficial interventions. With the recent licensing of memantine, clinicians finally have a drug option that will delay disease progression. Severe Dementia is the first book to focus exclusively on severe dementia. It addresses both the clinical features of the disease and the social aspects of care. Introductory chapters on the differential diagnosis, neurochemistry and molecular pathology of severe dementia set the scene for the clinical discussion. Detailed clinical chapters on cognitive function, depression, physical effects, staging and function follow. All therapeutic interventions are then discussed, including memantine, anticholinesterases, neuroleptics and non-pharmacological treatment. The final chapters review the social and economic aspects of dementia care, including family involvement, person-centered care, palliative care, ethics and health economics. Written and edited by experts in geriatric psychiatry and geriatrics, Severe Dementia is of value to all clinicians involved in the management of this complex and vulnerable group of patients. It is also of interest to general practitioners and carers in nursing homes.

Book The Person with Alzheimer s Disease

Download or read book The Person with Alzheimer s Disease written by Phyllis Braudy Harris and published by JHU Press. This book was released on 2002-06-06 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first book to provide a comprehensive look at what it's like to have dementia and the subjective experience of living with progressive memory loss. Few families are untouched by Alzheimer's disease or a related dementia. Moving accounts of what it is like to care for someone with this disease have already been published, as well as how-to books that offer caregivers advice and information on coping. But this book is the first to provide a comprehensive report of what it is like to have dementia oneself—the subjective experience of living with progressive memory loss. Each chapter discusses a different aspect of having dementia, from the initial assessment and diagnosis through placement in a nursing home. The discussions are grounded in qualitative research and case studies, which convey the variable and personal nature of the experience. They seek to help clinicians, researchers, students, and caregivers (both professionals and family members) understand the experience of dementia, and thereby to promote better caregiving through a person-centered approach. Contributors: Kathleen Kahn-Denis, Judson Retirement Community; Casey Durkin, a psychotherapist in Cleveland, Ohio; Jane Gilliard, Dementia Voice, UK; Phyllis Braudy Harris, John Carroll University; John Keady, University of Wales, UK; John Killick, University of Stirling, UK; Rebecca G. Logsdon, University of Washington; Charlie Murphy, University of Stirling, UK; Alison Phinney, University of British Columbia, Canada; Steven R. Sabat, Georgetown University; Dorothy Seman, Alzheimer's Family Care Center, Chicago; Lisa Snyder, University of California, San Diego; Jane Stansell, Alzheimer's Family Care Center, Chicago; Gloria Sterin, Shaker Heights, Ohio; Jon C. Stuckey, Messiah College; Robyn Yale, Consultant to the Alzheimer's Association, San Francisco; Rosalie Young, Wayne State University School of Medicine.

Book Memory in Literature

Download or read book Memory in Literature written by S. Nalbantian and published by Springer. This book was released on 2002-11-15 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the first to discover and probe in depth memory phenomena captured in literary works. Using literature as a laboratory for the workings of the mind, this comparative study of writers from Jean-Jacques Rousseau to Octavio Paz, including Proust, Breton, Woolf and Faulkner, uncovers valuable material for the classification of the memory process. Nalbantian's daring interdisciplinary work, involving literature, science, and art, forges a new model for dialogue between the disciplines.

Book Beans  Roots and Leaves

Download or read book Beans Roots and Leaves written by Paul Bernard Foley and published by Tectum Verlag DE. This book was released on 2003 with total page 932 pages. Available in PDF, EPUB and Kindle. Book excerpt: Parkinsonism of various types has long been a debilitating and cruel affliction for significant numbers of people, and even today the cure remains elusive. The present volume explores the colorful and sometimes alarming history of the attempts to provide at least some relief from the symptoms of this disorder, commencing with interesting reports from ancient India and medieval Europe and continuing until the present time. Especial attention is devoted to L-DOPA therapy, still the leading pharmacological approach to the disorder more than forty years after its first application, and its place in the development of neurochemistry. But the employment of solanaceous plant alkaloid-based therapies, which dominated antiparkinsonian therapy until the mid-20th century, and the broad range of other approaches which found varying degrees of popularity, including those stimulated by the encephalitis epidemic which appeared in Europe during the First World War, are also discussed. The author concludes that antiparkinsonian therapy was never 'irrational', but was rather always determined by prevailing medical, pharmacological and scientific paradigms, so that its history is inextricably linked with experimental and clinical developments in these fields.

Book Pathologies of Speech and Language

Download or read book Pathologies of Speech and Language written by Ben Maassen and published by . This book was released on 1999-06-02 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: Speech and language pathologies, and to improve clinical tools for assessment rehabilitation and treatment.

Book Biosocialities  Genetics and the Social Sciences

Download or read book Biosocialities Genetics and the Social Sciences written by Sahra Gibbon and published by Routledge. This book was released on 2007-07-20 with total page 387 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biosocialities, Genetics and the Social Sciences explores the social, cultural and economic transformations that result from innovations in genomic knowledge and technology. This pioneering collection uses Paul Rabinow’s concept of biosociality to chart the shifts in social relations and ideas about nature, biology and identity brought about by developments in biomedicine. Based on new empirical research, it contains chapters on genomic research into embryonic stem cell therapy, breast cancer, autism, Parkinson’s and IVF treatment, as well as on the expectations and education surrounding genomic research. It covers four main themes: novel modes of identity and identification, such as genetic citizenship the role of institutions, ranging from disease advocacy organizations and voluntary organizations to the state the production of biological knowledge, novel life-forms, and technologies the generation of wealth and commercial interests in biology. Including an afterword by Paul Rabinow and case studies on the UK, US, Canada, Germany, India and Israel, this book is key reading for students and researchers of the new genetics and the social sciences – particularly medical sociologists, medical anthropologists and those involved with science and technology studies.

Book The Neuroscience of Hallucinations

Download or read book The Neuroscience of Hallucinations written by Renaud Jardri and published by Springer Science & Business Media. This book was released on 2012-09-25 with total page 567 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hallucinatory phenomena have held the fascination of science since the dawn of medicine, and the popular imagination from the beginning of recorded history. Their study has become a critical aspect of our knowledge of the brain, making significant strides in recent years with advances in neuroimaging, and has established common ground among what normally are regarded as disparate fields. The Neuroscience of Hallucinations synthesizes the most up-to-date findings on these intriguing auditory, visual, olfactory, gustatory, and somatosensory experiences, from their molecular origins to their cognitive expression. In recognition of the wide audience for this information among the neuroscientific, medical, and psychology communities, its editors bring a mature evidence base to highly subjective experience. This knowledge is presented in comprehensive detail as leading researchers across the disciplines ground readers in the basics, offer current cognitive, neurobiological, and computational models of hallucinations, analyze the latest neuroimaging technologies, and discuss emerging interventions, including neuromodulation therapies, new antipsychotic drugs, and integrative programs. Among the topics covered: Hallucinations in the healthy individual. A pathophysiology of transdiagnostic hallucinations including computational and connectivity modeling. Molecular mechanisms of hallucinogenic drugs. Structural and functional variations in the hallucinatory brain in schizophrenia. The neurodevelopment of hallucinations. Innovations in brain stimulation techniques and imaging-guided therapy. Psychiatrists, neurologists, neuropsychologists, cognitive neuroscientists, clinical psychologists, and pharmacologists will welcome The Neuroscience of Hallucinations as a vital guide to the current state and promising future of their shared field.

Book Medical Image Computing and Computer Assisted Intervention    MICCAI 2012

Download or read book Medical Image Computing and Computer Assisted Intervention MICCAI 2012 written by Nicholas Ayache and published by Springer. This book was released on 2012-08-28 with total page 645 pages. Available in PDF, EPUB and Kindle. Book excerpt: The three-volume set LNCS 7510, 7511, and 7512 constitutes the refereed proceedings of the 15th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2012, held in Nice, France, in October 2012. Based on rigorous peer reviews, the program committee carefully selected 252 revised papers from 781 submissions for presentation in three volumes. The third volume includes 79 papers organized in topical sections on diffusion imaging: from acquisition to tractography; image acquisition, segmentation and recognition; image registration; neuroimage analysis; analysis of microscopic and optical images; image segmentation; diffusion weighted imaging; computer-aided diagnosis and planning; and microscopic image analysis.

Book Wine

    Book Details:
  • Author : Merton Sandler
  • Publisher : CRC Press
  • Release : 2002-12-19
  • ISBN : 0203361385
  • Pages : 674 pages

Download or read book Wine written by Merton Sandler and published by CRC Press. This book was released on 2002-12-19 with total page 674 pages. Available in PDF, EPUB and Kindle. Book excerpt: Interest in wine science has grown enormously over the last two decades as the health benefits of moderate wine consumption have become firmly established in preventing heart disease, stroke, cancer and dementia. The growth of molecular biology has allowed proper investigation of grapevine identity and lineage and led to improvements in the winemak

Book Cognitive Screening Instruments

Download or read book Cognitive Screening Instruments written by A. J. Larner and published by Springer. This book was released on 2016-11-30 with total page 351 pages. Available in PDF, EPUB and Kindle. Book excerpt: This revised and updated second edition provides a practical and structured overview of some of the most commonly used and easily available cognitive screening instruments applicable in the outpatient clinic and bedside setting. It now includes additional chapters on AD8 and also methodological aspects of systematic cognitive screening instrument assessment from the Cochrane Dementia and Cognitive Improvement Group. Expert authors from around the world equip the reader with clear instructions on the usage of each screening instrument, its strengths and weaknesses, and the time required for administration. Rules on scoring are also provided, such as how to correct for variations in the patient’s age or education, and suggested cut-off scores. Cognitive Screening Instruments: A Practical Approach, Second Edition is aimed at both clinicians and professionals in disciplines allied to medicine who are called upon to assess patients with possible cognitive disorders, including neurologists, old age psychiatrists, neuropsychologists, primary care physicians, dementia support workers, and members of memory assessment teams.

Book Relational Mental Health

    Book Details:
  • Author : J. Guimón
  • Publisher : Springer Science & Business Media
  • Release : 2004
  • ISBN : 0306478579
  • Pages : 406 pages

Download or read book Relational Mental Health written by J. Guimón and published by Springer Science & Business Media. This book was released on 2004 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: Relational Mental Health contains current evidence-based diagnosis and therapeutic interventions for people with mental disorders. Students and professionals alike will find the mental health field addressed as a whole in a coherent and understandable way. Readers are offered a unified presentation of psychological and sociological approaches to diagnosis and treatment.