Download or read book Toxins and Cancer Therapy written by Adam E. Snook and published by MDPI. This book was released on 2021-03-02 with total page 104 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer has been a patient-specific and difficult-to-treat disease for decades, resulting in more deaths since 1900 than all other diseases except cardiovascular diseases. As societies around the world continue to shift towards an aging population, the social and economic burden created by cancer will only rise in the coming decades, necessitating continued improvement in our cancer therapies. Remarkably, in the late 1800s, bone surgeon William Coley serendipitously discovered that bacteria could be administered to patients as an effective (and sometimes toxic) form of cancer therapy known as "Coley's Toxins". His discoveries unknowingly led to two fields of cancer therapy that have been in development for decades and are now leading to significant improvements in therapy for cancer patients: immune-based and toxin-based therapies for cancer. Articles included here discuss the discoveries that emerged from Coley's Toxins that enable us to harness the immune system and microbial toxins to combat cancers, as oncology shifts from a field dominated by chemotherapy for most of the 20th century to biologic therapies that will dominate the 21st century.
Download or read book Toxins and Cancer Therapy written by Adam E. Snook and published by . This book was released on 2021 with total page 104 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer has been a patient-specific and difficult-to-treat disease for decades, resulting in more deaths since 1900 than all other diseases except cardiovascular diseases. As societies around the world continue to shift towards an aging population, the social and economic burden created by cancer will only rise in the coming decades, necessitating continued improvement in our cancer therapies. Remarkably, in the late 1800s, bone surgeon William Coley serendipitously discovered that bacteria could be administered to patients as an effective (and sometimes toxic) form of cancer therapy known as "Coley's Toxins". His discoveries unknowingly led to two fields of cancer therapy that have been in development for decades and are now leading to significant improvements in therapy for cancer patients: immune-based and toxin-based therapies for cancer. Articles included here discuss the discoveries that emerged from Coley's Toxins that enable us to harness the immune system and microbial toxins to combat cancers, as oncology shifts from a field dominated by chemotherapy for most of the 20th century to biologic therapies that will dominate the 21st century.
Download or read book Treatment of Bone and Soft Tissue Sarcomas written by Per-Ulf Tunn and published by Springer Science & Business Media. This book was released on 2008-12-28 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bone and soft tissue sarcomas represent only about 2% of all malignancies; however, their treatment – with the goal of curing the patient while preserving the functionality of the affected body part – can, unlike other malignancies, only be successful with therapy concepts devised by interdisciplinary teams. This volume provides an extensive up-to-date overview of the specific diagnostics and current treatment standards of these rare entities, presenting the various limb-sparing modalities for patients with bone and soft tissue sarcomas with special regard to innovative reconstructive options. The evaluation of quality of life based on validated scores and the individual methods of coping with the illness through creative artistic projects are also acknowledged and integrated in the whole concept.
Download or read book Cancer Therapy written by Ralph W. Moss and published by . This book was released on 1992 with total page 532 pages. Available in PDF, EPUB and Kindle. Book excerpt: This thorough guide is a must-read for cancer patients and their families seeking treatment options.
Download or read book Venom and Toxin as Targeted Therapy written by Hang Fai (Henry) Kwok and published by MDPI. This book was released on 2019-10-01 with total page 178 pages. Available in PDF, EPUB and Kindle. Book excerpt: Targeted therapy has developed significantly in the last one and half decades, prescribing specific medications for treatment of particular diseases, such as cancer, diabetes, and heart disease. One of the most exciting recent developments in targeted therapies was the isolation of disease-specific molecules from natural resources, such as animal venoms and plant metabolites/toxins, for use as templates for new drug motif designs. In addition, the study of venom proteins/peptides and toxins naturally targeted mammalian receptors and demonstrated high specificity and selectivity towards defined ion channels of cell membranes. Research has also focsed intensely on receptors. The focus of this Special Issue of Toxins addressed the most recent advances using animal venoms, such as frog secretions, bee/ant venoms and plant/fungi toxins, as medicinal therapy. Recent advances in venom/toxin/immunotoxins for targeted cancer therapy and immunotherapy, along with using novel disease-specific venom-based protein/peptide/toxin and currently available FDA-approved drugs for combinationtreatments will be discussed. Finally, we included an overview of select promising toad/snake venom-based peptides/toxins potentially able to address the forthcoming challenges in this field. Both research and review articles proposing novelties or overviews, respectively, were published in this Special Issue after rigorous evaluation and revision by expert peer reviewers.
Download or read book Bacterial Toxins for Cancer Therapy written by Nour-Imene Zahaf and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Immunotoxins written by Arthur E. Frankel and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 550 pages. Available in PDF, EPUB and Kindle. Book excerpt: Where do you begin to look for a recent, authoritative article on the diagnosis or management of a particular malignancy? The few general oncology textbooks are generally out of date. Single papers in specialized journals are informative but seldom comprehensive; these are more often preliminary reports on a very limited number of patients. Certain general journals frequently publish good indepth reviews of cancer topics, and published symposium lectures are often the best overviews available. Un fortunately, these reviews and supplements appear sporadically, and the reader can never be sure when a topic of special interest will be covered. Cancer Treatment and Research is a series of authoritative volumes which aim to meet this need. It is an attempt to establish a critical mass of oncology literature covering virtually all oncology topics, revised frequently to keep the coverage up-to-date, easily available on a single library shelf or by a single personal subscription. We have approached the problem in the following fashion. First, by dividing the oncology literature into specific subdivisions such as lung cancer, genitourinary cancer, pediatric oncology, etc. Second, by asking eminent authorities in each of these areas to edit a volume on the specific topic on an annual or biannual basis. Each topic and tumor type is covered in a volume appearing frequently and predictably, discussing current diagnosis, staging, markers, all forms of treatment modalities, basic biology, and more.
Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book How Tobacco Smoke Causes Disease written by United States. Public Health Service. Office of the Surgeon General and published by . This book was released on 2010 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
Download or read book Chimeric Toxins written by Haya Lorberboum-Galski and published by CRC Press. This book was released on 2002-05-30 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bacteria and plants produce powerful toxins that can cause a variety of diseases, some of which are lethal for many animal species. The mechanisms of action are common to many of these toxins and represent general pathways for the interaction of a number of biomolecules with target cells, such as binding to specific surface receptors, internalizati
Download or read book Bacterial Therapy of Cancer written by Robert Hoffman and published by Humana. This book was released on 2016-02-05 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume explores the evolution of bacterial cancer therapy and describes the modern techniques used in therapy today. The chapters in this book cover a broad range of topics such as the development of tumor-targeting Salmonella typhimurium A1-R, a microfluidic device for precise quantification of the interactions between tumor-targeting bacteria and tumor tissue, non-invasive in vivo imaging of bacteria-mediated cancer therapy using bio-luminescent bacteria, methods to achieve remote-control of therapeutic gene expression in tumor-targeting bacteria, and cell-cycle decoy of cancer cells resistant to cytotoxic drugs to drug sensitivity by S. typhimurium A1-R. This book concludes with a chapter on the future potential of bacterial therapy of cancer. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Thorough and informative, Bacterial Therapy of Cancer: Methods and Protocols is a valuable resource for anyone who is interested in cancer and bacterial therapy.
Download or read book Holland Frei Cancer Medicine written by Robert C. Bast, Jr. and published by John Wiley & Sons. This book was released on 2017-03-10 with total page 2004 pages. Available in PDF, EPUB and Kindle. Book excerpt: Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates
Download or read book Cytotoxins and Immunotoxins for Cancer Therapy written by Koji Kawakami and published by CRC Press. This book was released on 2004-11-15 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent advances in cytotoxins and immunotoxins are accelerating our understanding of cancer and leading to more effective therapeutic treatments. Although a large number of articles have been published on these cytotoxins and immunotoxins, this important information has yet to be compiled into one comprehensive resource. For the first time,
Download or read book The Gerson Therapy written by Charlotte Gerson and published by Kensington Books. This book was released on 2001 with total page 419 pages. Available in PDF, EPUB and Kindle. Book excerpt: Offers a nutritional program that utilizes the healing powers of organic fruits and vegetables to reverse the effects of cancer and other illnesses.
Download or read book Nanomaterials for Cancer Therapy written by Challa S. S. R. Kumar and published by Wiley-VCH. This book was released on 2006-07-24 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: This first comprehensive overview on nanotechnological approaches to cancer therapy brings together therapeutic oncology and nanotechnology, showing the various strategic approaches to selectively eliminating cancerous cells without damaging the surrounding healthy tissue. The strategies covered include magnetic, optical, microwave and neutron absorption techniques, nanocapsules for active agents, nanoparticles as active agents, and active and passive targeting, while also dealing with fundamental aspects of how nanoparticles cross biological barriers. A valuable single source gathering the many articles published in specialized journals often difficult to locate for members of the other disciplines involved.
Download or read book Venom and Toxin as Targeted Therapy written by Hang Fai Henry Kwok and published by . This book was released on 2019 with total page 1 pages. Available in PDF, EPUB and Kindle. Book excerpt: Targeted therapy has developed significantly in the last one and half decades, prescribing specific medications for treatment of particular diseases, such as cancer, diabetes, and heart disease. One of the most exciting recent developments in targeted therapies was the isolation of disease-specific molecules from natural resources, such as animal venoms and plant metabolites/toxins, for use as templates for new drug motif designs. In addition, the study of venom proteins/peptides and toxins naturally targeted mammalian receptors and demonstrated high specificity and selectivity towards defined ion channels of cell membranes. Research has also focsed intensely on receptors. The focus of this Special Issue of Toxins addressed the most recent advances using animal venoms, such as frog secretions, bee/ant venoms and plant/fungi toxins, as medicinal therapy. Recent advances in venom/toxin/immunotoxins for targeted cancer therapy and immunotherapy, along with using novel disease-specific venom-based protein/peptide/toxin and currently available FDA-approved drugs for combinationtreatments will be discussed. Finally, we included an overview of select promising toad/snake venom-based peptides/toxins potentially able to address the forthcoming challenges in this field. Both research and review articles proposing novelties or overviews, respectively, were published in this Special Issue after rigorous evaluation and revision by expert peer reviewers.
Download or read book Cancer Free Your Guide to Gentle Non toxic Healing Fifth Edition written by Bill Henderson and published by BookLocker.com, Inc.. This book was released on 2014-11-15 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: About the Book "If you love your stricken one, this is your Bible." said Denzel Koh of Brisbane, Australia after he healed his daughter's cancer using the information in a previous edition of this book. A cancer diagnosis always causes fear. All of us have seen relatives and friends destroyed by conventional cancer treatment. Now, thanks to books like this one and the Internet, you can quickly learn what you need to know. You can heal the cancer using natural, non-toxic substances that work. What you need is a guide to cut through the overwhelming jungle of information. This book provides that guide. The information in it has been refined over twelve years using feedback from real cancer survivors about what worked for them. Bill Henderson, one of the authors, has counseled about 4,000 cancer patients by phone and video in 64 countries. At least 3,000 of them have recovered using his information. He is not a medical professional. He is a "reporter" furnishing you with information that consists of "what he would do if he were you or your loved one." His coaching is available to you after you have read this book, if you need it. The co-author is Dr. Carlos Garcia, a formally trained M.D. who has broken out of that mold and trained himself to be a well-informed holistic physician. His Utopia Wellness clinic in Oldsmar, Florida regularly helps Stage IV cancer patients heal themselves. Bill Henderson has published 165 free newsletters on natural cancer treatment to 38,000 subscribers all over the world, starting in 1999. The information in these newsletters has now been incorporated into this, his third book. The book is up-to-date, specific and accurate. Bill and Dr. Garcia inform you of over 140 web sites and dozens of other books and newsletters you can use to expand your knowledge of natural cancer treatment. The self-treatments they recommend are harmless enough that you can start them immediately, without more research, if you like. They do not interfere with conventional cancer therapy, if that is your choice. In fact, they offset most of the side effects of that treatment. "Cancer is not a disease," says Bill. "It is a reaction to what your body has experienced. Reverse those causes and the cancer goes away. Continue what you did to reverse it and it stays away." Bill explains that there are four common characteristics of all cancers. These have been known since the 1920's: 1. Low oxygen uptake by the cells. 2. A weak immune system. 3. Toxins -- usually caused by diet and dental work. 4. Acidity -- again, usually caused by diet, as well as stress and dental work. Bill Henderson's and Dr. Garcia's recommended regimen tracks with the knowledge for which Otto Warburg, a famous German doctor and researcher, won a Nobel Prize in 1931. He described the cancer cell and stressed the need to reverse the above four characteristics of the cancer in order to heal it. None of these are addressed by conventional cancer treatment. Bill's mission to help cancer patients heal started with his experience with his former wife, Marjorie. Her ovarian cancer was treated with conventional cancer treatment from 1990 to 1994, when she died. Bill is convinced that the treatment killed her. He wants to help as many people as possible avoid her fate. Dr. Garcia's mission is to help cancer patients heal themselves starting in a controlled clinical environment and continuing at home. He has been doing this successfully for 15 years.
