Download or read book Toxicological Profile for 4 4 methylenebis 2 Chloroaniline MBOCA written by and published by . This book was released on 1994 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Toxicological Profile for 4 4 Methylenebis 2 Chloroaniline MBOCA written by and published by . This book was released on 2001-02 with total page 129 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides information about 4, 4'-Methylenebis (2-Chloroaniline) (MBOCA) & the human health effects of exposure. This chemical has been found in many sites identified by the EPA for long-term Federal cleanup activities. The report includes a Public Health Statement which explains the toxicologic properties of MBOCA in a nontechnical, Q&A format, & a review of the general health effects observed following exposure; a description of health effects; how the chemical can affect children; & information on its chemical & physical properties, production, use & disposal, potential for human exposure, analytical methods, & regulations & advisories.
Download or read book Eighth Annual Report on Carcinogens written by Barry Leonard and published by DIANE Publishing. This book was released on 1999-11 with total page 279 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discusses individual substances, mixtures of chemicals, or exposure circumstances associated with technological processes which are known to be human carcinogens or which may reasonably be anticipated to be human carcinogens. Also contains information relating to estimated exposures and exposure standards or guidelines. Chapters: delisted substances; profiles for agents, substances, mixtures or exposure circumstances known to be human carcinogens, or reasonably anticipated to be human carcinogens; list of manufacturing processes, occupations, and exposure circumstances classified; and listing/delisting procedures.
Download or read book Annual Report on Carcinogens written by and published by . This book was released on 1998 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Report on Carcinogens written by and published by . This book was released on 1998 with total page 648 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Integrated Safety and Risk Assessment for Medical Devices and Combination Products written by Shayne C. Gad and published by Springer Nature. This book was released on 2020-02-24 with total page 490 pages. Available in PDF, EPUB and Kindle. Book excerpt: While the safety assessment (“biocompatibility”) of medical devices has been focused on issues of local tissue tolerance (irritation, sensitization, cytotoxicity) and selected quantal effects (genotoxicity and acute lethality) since first being regulated in the late 1950s, this has changed as devices assumed a much more important role in healthcare and became more complex in both composition and in their design and operation. Add to this that devices now frequently serve as delivery systems for drugs, and that drugs may be combined with devices to improve device performance, and the problems of ensuring patient safety with devices has become significantly more complex. A part of this, requirements for ensuring safety (once based on use of previously acceptable materials – largely polymers and metals) have come to requiring determining which chemical entities are potentially released from a device into patients (and how much is released). Then an appropriate and relevant (yet also conservative) risk assessment must be performed for each identified chemical structure. The challenges inherent in meeting the current requirements are multifold, and this text seeks to identify, understand, and solve all of them. • Identify and verify the most appropriate available data. • As in most cases such data is for a different route of exposure, transform it for use in assessing exposure by the route of interest. • As the duration (and rate) of exposure to moieties released from a device are most frequently different (longer) than what available data speaks to, transformation across tissue is required. • As innate and adaptive immune responses are a central part of device/patient interaction, assessing potential risks on this basis are required. • Incorporating assessments for special populations such as neonates. • Use of (Q)SAR (Quantitative Structure Activity Relationships) modeling in assessments. • Performance and presentation of integrative assessments covering all potential biologic risks. Appendices will contain summarized available biocompatibility data for commonly used device materials (polymers and metals) and safety assessments on the frequently seen moieties in extractions from devices.
Download or read book Report on Carcinogens 12th Ed written by Nat. Toxicology Program (NTP) (NIH) and published by DIANE Publishing. This book was released on 2011-10-08 with total page 507 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Report on Carcinogens (RoC) is a congressionally mandated, science-based, public health document that identifies and discusses agents, substances, mixtures, or exposure circumstances (hereinafter referred to as "substances") that may pose a hazard to human health by virtue of their carcinogenicity. For each listed substance, the report contains a substance profile which provides information on (1) the listing status, (2) cancer studies in humans and animals, (3) studies of genotoxicity (ability to damage genes) and biologic mechanisms, (4) the potential for human exposure to these substances, and (5) Federalregulations to limit exposures. Eight substances have been added to this 12th ed. of the report, which now includes 240 listings. The industrial chemical formaldehyde and a botanical known as aristolochic acids are listed as known human carcinogens. Six other substances captafol, cobalt-tungsten carbide (in powder or hard metal form), certain inhalable glass wool fibers, o-nitrotoluene, riddelliine, and styrene are added as substances that are reasonably anticipated to be human carcinogens. Figures. This is a print on demand report.
Download or read book Fact Sheets on Hazardous Substances written by and published by . This book was released on 1993 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book ATSDR fact Sheets written by and published by . This book was released on 1995 with total page 84 pages. Available in PDF, EPUB and Kindle. Book excerpt: The fact sheet series presents summaries and answers questions about hazardous substances and their health effects.
Download or read book IARC Monographs on the Evaluation of Carcinogenic Risks to Humans written by and published by . This book was released on 1988 with total page 644 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book A Review of Human Carcinogens F Chemical Agents and Related Occupations written by International Agency for Research on Cancer and published by International Agency for Research on Cancer. This book was released on 2012-09-24 with total page 636 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume 100 compiles information on tumor sites and mechanisms of carcinogenesis. About half of the agents classified in Group 1 were last reviewed more than 20 years ago, before mechanistic studies became prominent in evaluations of carcinogenicity. In addition, more recent epidemiological studies and animal cancer bioassays have demonstrated that many cancer hazards reported in earlier studies were later observed in other organs or through different exposure scenarios. Much can be learned by updating the assessments of agents that are known to cause cancer in humans. Accordingly, IARC has selected A Review of Human Carcinogensto be the topic for Volume 100. It is hoped that this volume, by compiling the knowledge accumulated through several decades of cancer research, will stimulate cancer prevention activities worldwide, and will be a valued resource for future research to identify other agents suspected of causing cancer in humans. Volume 100 was developed by six separate Working Groups: Pharmaceuticals; Biological agents; Metals, particles, and fibres; Radiation; Personal habits and household exposures; Chemical agents and related occupations. Because the scope of Volume 100 is so broad, its Monographs are focused on key information. Each Monograph presents a description of a carcinogenic agent and how people are exposed, critical overviews of the epidemiological studies and animal cancer bioassays, and a concise review of the agent's toxicokinetics, plausible mechanisms of carcinogenesis, and potentially susceptible populations, and life-stages. Details of the design and results of individual epidemiological studies and animal cancer bioassays are summarized in tables. Short tables that highlight key results are printed in Volume 100, and more extensive tables that include all studies appear on the Monographs programe website (http://monographs.iarc.fr/). For a few well-established associations (for example, tobacco smoke and human lung cancer), it was impractical to include all studies, even in the website tables. In those instances, the rationale for inclusion or exclusion of sets of studies is given.
Download or read book Government Reports Announcements Index written by and published by . This book was released on 1995 with total page 768 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Hazardous Chemicals Desk Reference written by Richard J. Lewis, Sr. and published by John Wiley & Sons. This book was released on 2008-06-13 with total page 1974 pages. Available in PDF, EPUB and Kindle. Book excerpt: Offers a "safety profile" of 5000 of the most important hazardous chemicals. Features unique Chemical Safety Profiles that provide a quick overview of the hazards, synonyms, and physical properties of a variety of chemicals. Details government agency standards and recommendations on the handling of each chemical. Includes three cross-indices to permit rapid location of a material by its Chemical Abstract Service (CAS) number, a synonym for the material, or the DOT Guide Number. Features new chemical entries unavailable in previous versions.
Download or read book Poisoning Toxicology Compendium written by and published by . This book was released on 1998 with total page 1480 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Food Additives Handbook written by Richard J. Lewis and published by Springer Science & Business Media. This book was released on 1989 with total page 644 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Each additive is covered in a separate, alphabetically listed entry." Entries give CAS number, properties, synonyms, use in foods, and safety profile.
Download or read book Safety and Health at Work ILO CIS Bulletin written by and published by . This book was released on 1998 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Poisoning and Toxicology Compendium written by Jerrold B. Leikin and published by Lexi-Comp. This book was released on 1998 with total page 1550 pages. Available in PDF, EPUB and Kindle. Book excerpt:
